Novel Biomarkers and Treatment Strategies for Gastrointestinal Malignancies: From the Bench to the Bedside
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Oncology".
Deadline for manuscript submissions: 26 November 2026 | Viewed by 97
Special Issue Editor
2. Darent Valley Hospital, Dartford, UK
3. Post-Graduation Programme in Medicine, Universidade Nove de Julho (UNINOVE), São Paulo, Brazil
Interests: medical oncology; immunotherapy; biomarkers; Gastrointestinal (GI) malignancies; GI oncology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Gastrointestinal (GI) malignancies—encompassing colorectal, gastric, esophageal, hepatic, and pancreatic cancers—account for a substantial proportion of global cancer-related mortality. Despite significant surgical advances and the implementation of multimodal therapies, a large subset of patients still face poor prognoses due to late-stage diagnosis and primary or acquired therapeutic resistance. To overcome these clinical hurdles, the seamless integration of translational research is paramount.
This Special Issue aims to highlight the latest breakthroughs in GI oncology, bridging the critical gap between laboratory discoveries and clinical implementation. We invite researchers and clinicians to submit original articles and comprehensive reviews that explore the dynamic interplay between fundamental molecular biology and clinical application. Key areas of interest include the discovery, validation, and clinical utility of novel genomic, transcriptomic, and liquid biopsy biomarkers for early detection and disease monitoring, with a special emphasis on exosomes and extracellular vesicles. Furthermore, we welcome the submission of cutting-edge research on innovative treatment paradigms, particularly the evolving role of immunotherapy, targeted molecular interventions, new drug development, and exosome-based nanotherapeutics.
By assembling high-impact translational research, we seek to accelerate the journey of scientific discoveries from bench to bedside, ultimately driving the future of precision medicine and improving survival outcomes for patients with GI malignancies.
Prof. Dr. Ramon Andrade de Mello
Guest Editor
Manuscript Submission Information
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Keywords
- gastrointestinal (GI) malignancies
- medical oncology
- immunotherapy
- biomarkers
- target therapies
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