Obstructive Sleep Apnea: Advances and Challenges in Diagnosis, Phenotyping, and Clinical Impact
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Respiratory Medicine".
Deadline for manuscript submissions: 10 December 2026 | Viewed by 111
Special Issue Editors
Interests: sleep breathing disorders; non-invasive mechanical ventilation; critical care ultrasound; severe reactive airway disease management
Interests: sleep medicine; parasomnias; sleep disorders; sleep education; tele-sleep medicine; neurological sleep disorders
Interests: sleep medicine; obstructive sleep apnea; sleep-disordered breathing; pulmonary medicine; critical care; respiratory physiology; cardiopulmonary interactions
Special Issue Information
Dear Colleagues,
Obstructive sleep apnea (OSA) is a highly prevalent and underdiagnosed sleep-related breathing disorder with far‑reaching implications for cardiovascular, metabolic, and neuropsychiatric health. Growing evidence links OSA to hypertension, coronary artery disease, heart failure, diabetes, mood disorders, and cognitive impairment, underscoring its importance as a major public health concern worldwide. Despite advances in awareness and treatment, significant challenges remain in the accurate diagnosis, phenotyping, and risk stratification of affected individuals across diverse clinical and population settings.
This Special Issue aims to present and disseminate recent advances related to the diagnosis, phenotyping, and clinical impact of obstructive sleep apnea, while also highlighting the challenges that remain. We consider contributions that address mechanistic insights, epidemiology, innovative diagnostic approaches, clinical management strategies, and the multisystem consequences of OSA. In particular, this Special Issue welcomes original research and state-of-the-art reviews examining contemporary diagnostic and screening strategies for OSA, including their performance characteristics, limitations, and appropriate clinical applications.
Submissions providing critical evaluations of established and emerging diagnostic tools such as laboratory-based polysomnography, home sleep apnea testing, and simplified screening modalities are encouraged, especially when contextualized within real‑world practice, resource‑constrained environments, or specific patient populations. By integrating methodological rigor with clinical relevance, this Special Issue seeks to highlight opportunities to improve diagnostic accuracy, personalize care, and ultimately reduce the burden of untreated OSA.
We invite basic, translational, and clinical investigations as well as narrative reviews that collectively advance understanding and management of obstructive sleep apnea.
Dr. Muhammad A. Rishi
Dr. Muna Irfan
Dr. Andrew Namen
Guest Editors
Manuscript Submission Information
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Keywords
- obstructive sleep apnea
- sleep diagnostics
- screening tools
- pulse oximetry
- polysomnography
- home sleep apnea testing
- diagnostic accuracy
- phenotyping
- cardiometabolic comorbidity
- neuropsychiatric outcomes
- sleep -disordered breathing
- real-world implementation
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