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Cesarean Section Versus Vaginal Delivery

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Obstetrics & Gynecology".

Deadline for manuscript submissions: 10 April 2026

Special Issue Editors


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Guest Editor
Department of Obstetrics and Gynecology, ‘Grigore T. Popa’ University of Medicine and Pharmacy, 700115 Iasi, Romania
Interests: pregnancy; obstetrics and gynecology; placenta accreta spectrum; cesarean section; childbirth (obstetrical ultrasound and fetal and placental IRM; infections during pregnancy); IUGR; cesarean scar pathology
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
1. Department of Obstetrics and Gynecology, University of Alberta, Edmonton, AB T6G 2R3, Canada
2. Department of Neuroscience, University of Lethbridge, Lethbridge, AB T1K 3M4, Canada
Interests: obesity in pregnancy; gestational diabetes; nutrition in pregnancy; gestational weight gain; pregnancy outcomes
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Department of Obstetrics and Gynecology, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania
Interests: gynecology; 4D ultrasound; fetal medicine; colposcopy
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Although the processes of labor and birth have existed since the emergence of animal and then human species, recent years have brought significant technical advancements aimed at ensuring safer deliveries.

With respect to vaginal birth, new labor induction methods have been developed to reduce the rate of cesarean sections. Cervical ripening techniques have diversified, ranging from the Foley catheter and Cook balloon to prostaglandin administration and laminaria insertion, each with its own advantages and limitations.

Ultrasound has become an increasingly valuable tool, both in assessing cervical readiness through elastography (offering a more objective alternative to the Bishop score) and in evaluating labor progression. Dynamic parameters such as the angle of progression, head–perineum distance, and fetal position can help estimate the likelihood of successful vaginal delivery or the need for cesarean section.

Ultrasound can also detect intrapartum trauma and assess uterine scar quality, contributing to the risk stratification of uterine rupture and guiding the decision against TOLAC (Trial of Labor After Cesarean). Furthermore, it plays a role in identifying placental adhesion abnormalities, with MRI serving as a second-line investigation when needed.

These objective evaluations, which replace traditional clinical assessments with quantifiable parameters, may lay the groundwork for AI-assisted labor monitoring.

Indications for cesarean delivery have evolved as well. Some are now applied excessively, often due to medicolegal concerns. Thus, malpractice related to labor and delivery management is also a relevant theme for this Special Issue.

Neonatal outcomes following vaginal births—either spontaneous or assisted—versus cesarean delivery merit further investigation, as do the criteria for labor induction and cesarean indication in specific clinical scenarios such as previous uterine surgery, fetal growth restriction, abnormal presentations, placenta accreta spectrum, and vasa previa.

Cesarean birth has also been shown to alter fetal and neonatal microbiota when compared to vaginal delivery, with medium- and long-term health consequences that are still not fully understood.

Psychological changes induced by childbirth and their subsequent effects over time represent another important topic worthy of further exploration.

Submissions of original research, comprehensive reviews, and related works on these topics are welcomed for inclusion in this Special Issue.

Dr. Demetra Gabriela Socolov
Dr. Angela Vinturache
Prof. Dr. Liana Ples
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • cesarean section
  • vaginal delivery
  • birth outcomes
  • birth complications
  • delivery mode
  • labor process
  • obstetric care
  • trial of labor after cesarean (TOLAC)
  • intrapartum care
  • obstetric decision-making

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Published Papers

This special issue is now open for submission.
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