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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Disease Modifying Activity in Psoriasis and Atopic Dermatitis submission deadline 20 Feb 2026 | Viewed by 285 | Submission Open
Keywords: atopic dermatitis; biologics; psoriasis; disease-modifying treatment; small molecules; type 2 inflammation
(This special issue belongs to the Section Dermatology)
Novel Insights for Imaging and Therapy in Maternal and Fetal Medicine
edited by Xin Kang
submission deadline 20 Feb 2026 | Viewed by 254 | Submission Open
Keywords: prenatal imaging; prenatal diagnosis; fetal virtual autopsy; preeclampsia; macrosomia; preterm birth; pelvic floor
(This special issue belongs to the Section Obstetrics & Gynecology)
Endocrine Disorders in Children: 2nd Edition submission deadline 20 Feb 2026 | Viewed by 163 | Submission Open
Keywords: endocrinology; pediatrics; hormones; genetics; growth; nutrition; development  ; adolescence  ; prevention
(This special issue belongs to the Section Clinical Pediatrics)
Minimally Invasive Surgery for Gastrointestinal Disorder submission deadline 20 Feb 2026 | Viewed by 156 | Submission Open
Keywords: minimally invasive surgery; gastrointestinal disorder; laparoscopy; robotic surgery; colorectal surgery; gastric surgery; endoscopic technique; oncological outcomes; surgical innovation
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Hypercholesterolemia: Update on Treatment Approaches and Outcomes
edited by and Lucia Barbieri
submission deadline 20 Feb 2026 | Viewed by 147 | Submission Open
Keywords: hypercholesterolemia; dyslipidemia; atherosclerosis; cardiovascular risk; LDL; HDL; lipoprotein(a)
(This special issue belongs to the Section Cardiovascular Medicine)
Advances in the Diagnosis and Management of Atherosclerosis submission deadline 20 Feb 2026 | Viewed by 143 | Submission Open
Keywords: atherosclerosis; cardiovascular disease; coronary artery disease; endothelial function; acute coronary syndromes
(This special issue belongs to the Section Cardiology)
Maxillofacial Surgery in the Modern Era: Surgical Advances and Clinical Innovation submission deadline 20 Feb 2026 | Viewed by 143 | Submission Open
Keywords: maxillofacial surgery; oral surgery; craniofacial surgery; plastic surgery; bone
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
Advances and Innovations in Radiology: From Contrast-Enhanced Mammography to Artificial Intelligence and Beyond
edited by
submission deadline 20 Feb 2026 | Viewed by 142 | Submission Open
Keywords: contrast-enhanced mammography (CEM); artificial intelligence; radiomics; diagnostic imaging innovations; inter-ventional radiology
(This special issue belongs to the Section Nuclear Medicine & Radiology)
Recent Advances and Future Perspectives on Spinal Surgeries
edited by
submission deadline 20 Feb 2026 | Viewed by 135 | Submission Open
Keywords: minimally invasive spine procedures; robotic-assisted spine surgery; image-guided navigation; spinal implants and biomaterials; artificial intelligence in spinal care; regenerative spine therapies; clinical outcomes in spine surgery; future trends in spinal interventions
(This special issue belongs to the Section Orthopedics)
Progress and Innovation in the Clinical Management of Psychosis
edited by
submission deadline 20 Feb 2026 | Viewed by 134 | Submission Open
Keywords: psychosis; schizophrenia; clinical interventions; neurobiological mechanisms; early intervention
(This special issue belongs to the Section Mental Health)
Myocarditis and Pericarditis: Clinical Advances and Current Challenges submission deadline 20 Feb 2026 | Viewed by 127 | Submission Open
Keywords: pericarditis; myocarditis; pericardial effusion; cardiac tamponade; interleukin-1 inhibitors; pericardium
(This special issue belongs to the Section Cardiovascular Medicine)
Innovations and Challenges in the Burden and Rehabilitation of Musculoskeletal Disorders submission deadline 20 Feb 2026 | Viewed by 127 | Submission Open
Keywords: musculoskeletal diseases; rehabilitation; physical therapy modalities; telemedicine; mobile applications; health information technology; patient-centered care; quality of life; health care innovation
(This special issue belongs to the Section Clinical Rehabilitation)
Rheumatoid Arthritis: Insights into Appropriate Diagnosis, Treatment and Management
edited by
submission deadline 20 Feb 2026 | Viewed by 117 | Submission Open
Keywords: rheumatoid arthritis; precision medicine; difficult-to-treat rheumatoid arthritis; late-onset rheumatoid arthritis; ageing society; comorbidities
(This special issue belongs to the Section Immunology & Rheumatology)
Clinical Updates on Acromegaly
edited by , Jowita Halupczok-Żyła, Aleksandra Gilis-Januszewska and Przemysław Witek
submission deadline 20 Feb 2026 | Viewed by 115 | Submission Open
Keywords: acromegaly; GH; IGH-1; growth hormone-secreting pituitary adenoma; pituitary adenoma
(This special issue belongs to the Section Endocrinology & Metabolism)
Metastatic Colorectal Cancer Beyond Second-Line Treatment
edited by Jacopo Giuliani
submission deadline 20 Feb 2026 | Viewed by 109 | Submission Open
Keywords: metastatic colorectal cancer; subsequent lines; chemotherapy; targeted agents; radiotherapy; local therapy
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Advances in Posttraumatic Stress Disorder (PTSD): Clinical Update
edited by An-Fu Hsiao and
submission deadline 20 Feb 2026 | Viewed by 109 | Submission Open
Keywords: PTSD; stellate ganglion block; transcranial magnetic stimulations; neurobiology; trauma disorders; mind– body medicine; psychophysiology
(This special issue belongs to the Section Mental Health)
New Insights in Cognitive Aging and Mild Cognitive Impairment submission deadline 20 Feb 2026 | Viewed by 107 | Submission Open
Keywords: cognitive aging; mild cognitive impairment; normative aging; neuropsychological assessment; diagnosis; gerontology; prevention; intervention; multidisciplinary approach; measurement
(This special issue belongs to the Section Geriatric Medicine)
Diagnosis and Treatment of Cardiovascular Diseases in the Elderly submission deadline 20 Feb 2026 | Viewed by 101 | Submission Open
Keywords: cardiovascular diseases; elderly population; diagnosis and management; age-related pathophysiology; frailty and cognitive impairment
(This special issue belongs to the Section Geriatric Medicine)
Clinical Advances in Meningioma Surgery
edited by
submission deadline 20 Feb 2026 | Viewed by 96 | Submission Open
Keywords: meningioma; cranial neurosurgery; brain tumors; skull base surgery; endoscopic neurosurgery; intraoperative techniques; surgical outcomes; minimally invasive neurosurgery; perioperative management; clinical meningioma research
(This special issue belongs to the Section Clinical Neurology)
Endoscopic Imaging for the Diagnosis and Treatment of Gastrointestinal Diseases
edited by Mariana Jinga and
submission deadline 20 Feb 2026 | Viewed by 94 | Submission Open
Keywords: endoscopy; endoscopic ultrasound; endoscopic retrograde cholangiopancreatography; artificial intelligence; diagnosis; therapy; decision making; endobiopsy
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Advances in the Personalized Management of Chronic Obstructive Pulmonary Disease (COPD)
edited by and Georgios Hillas
submission deadline 20 Feb 2026 | Viewed by 93 | Submission Open
Keywords: artificial intelligence; biologics; biomarkers; diagnostics; oscillometry; COPD pharmacotherapy; imaging
(This special issue belongs to the Section Respiratory Medicine)
Optimizing Rehabilitation in Kidney Disease
edited by Henry H. L. Wu and Rajkumar Chinnadurai
submission deadline 20 Feb 2026 | Viewed by 92 | Submission Open
Keywords: chronic kidney disease; renal rehabilitation; exercise intervention; nutrition; multidisciplinary; frailty; physical conditioning
(This special issue belongs to the Section Clinical Rehabilitation)
Bleeding and Thrombotic Complications in Patients with Premalignant Hematologic Conditions: Diagnostic and Therapeutic Challenges
edited by Vasiliki Gkalea and Despina Fotiou
submission deadline 20 Feb 2026 | Viewed by 91 | Submission Open
Keywords: bleeding; thrombosis; hematologic malignancies; premalignant hematologic conditions; clonal hematopoiesis of indeterminate potential (CHIP); clonal cytopenias of undetermined significance (CCUS); monoclonal gammopathy of undetermined significance (MGUS); monoclonal B-cell lymphocytosis (MBL); monoclonal gammopathy of thrombotic significance (MGTS); VITT-like MGTS
(This special issue belongs to the Section Hematology)
New Insights into Management of Chronic Rhinosinusitis submission deadline 20 Feb 2026 | Viewed by 79 | Submission Open
Keywords: chronic rhinosinusitis; management; surgery; minimally invasive surgery; surgical oncology; cancer surgery; skull base surgery; hoarseness; laryngeal neoplasms; laryngoscopy; general surgery; X-ray computed tomography
(This special issue belongs to the Section Otolaryngology)
Clinical Advances in Sepsis and Septic Shock
edited by and Lorenzo Ghiadoni
submission deadline 20 Feb 2026 | Viewed by 77 | Submission Open
Keywords: sepsis-induced coagulopathy; endothelial dysfunction in sepsis; fluid balance in sepsis
(This special issue belongs to the Section Emergency Medicine)
Recent Advances in Gynecologic Surgery
edited by Adam Ostrzenski
submission deadline 20 Feb 2026 | Viewed by 66 | Submission Open
Keywords: gynecologic surgery; pelvic reconstruction surgery; female stress urinary incontinence surgery; cosmetic gynecology surgery; surgical meshes slings; native tissue
(This special issue belongs to the Section Obstetrics & Gynecology)
Clinical Advances in Head and Neck Cancer Diagnostics and Treatment
edited by and Alice L. Tang
submission deadline 20 Feb 2026 | Viewed by 64 | Submission Open
Keywords: head and neck; reconstruction; free flap; surgical margin; biomarker; human papillomavirus (HPV); extranodal extension; immunotherapy; virtual surgical planning
(This special issue belongs to the Section Otolaryngology)
Mental Disorders, Cognitive Impairment and Dementia Among Older Adults submission deadline 21 Feb 2026 | 3 articles | Viewed by 3773 | Submission Open
Keywords: mental disorders; cognitive decline; dementia; older adults; mental health; exercise; physical function
(This special issue belongs to the Section Geriatric Medicine)
Advances in Plastic and Reconstructive and Aesthetic Surgery of Face, Breast and Body
edited by
submission deadline 24 Feb 2026 | 3 articles | Viewed by 4806 | Submission Open
Keywords: reconstructive surgery; academic plastic surgery; research; social media in plastic surgery; breast surgery
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
Current and Emerging Treatment Options for Aortic Aneurysms
edited by Spyros Ioannis Papadoulas and
submission deadline 24 Feb 2026 | Viewed by 130 | Submission Open
Keywords: thoracic aortic aneurysms; abdominal aortic aneurysm; vascular surgery; cardiac surgery; treatment
(This special issue belongs to the Section Vascular Medicine)
Acute Respiratory Failure: Innovations and Clinical Insights
edited by
submission deadline 25 Feb 2026 | 3 articles | Viewed by 20146 | Submission Open
Keywords: ARF; mechanical ventilation; VILI; PSILI; NIV; HFNO; weaning; EIT; lung US
(This special issue belongs to the Section Intensive Care)
Interventional Pulmonology: Advances and Future Directions
edited by Martina Ferioli and Piero Candoli
submission deadline 25 Feb 2026 | 6 articles | Viewed by 10787 | Submission Open
Keywords: interventional pulmonology; lung nodule; lung cancer; diagnosis; bronchoscopy; rigid bronchoscopy; airway stent; airway stenosis; mediastinal staging
(This special issue belongs to the Section Respiratory Medicine)
(Recent Advances) Treating Psychiatry Disorders in Children and Adolescents: From Theory to Practice: 2nd Edition submission deadline 25 Feb 2026 | 5 articles | Viewed by 9067 | Submission Open
Keywords: intervention program; youth psychopathology; internalizing disorders; externalizing disorders; psychiatric disorders
(This special issue belongs to the Section Mental Health)
Advancing Pediatric Sports Medicine: Insights and Innovations
edited by Brian C. Lau
submission deadline 25 Feb 2026 | 4 articles | Viewed by 7011 | Submission Open
Keywords: sport surgery; patellar instability; early sport specialization; triplane fractures; pediatric sports medicine; orthopedic surgery; access to care; arthroscopic
(This special issue belongs to the Section Orthopedics)
Knee Arthroplasty Surgery: Management and Future Opportunities: 2nd Edition submission deadline 25 Feb 2026 | 5 articles | Viewed by 6813 | Submission Open
Keywords: knee; knee replacement; knee arthroplasty; knee alignment technique; robotic knee arthroplasty
(This special issue belongs to the Section Orthopedics)
New Advances in Total Knee Arthroplasty
edited by
submission deadline 25 Feb 2026 | 4 articles | Viewed by 6201 | Submission Open
Keywords: artificial intelligence; bone tumors; knee joint; knee pain; knee replacement; knee surgery; orthopedic surgery; osteoarthritis; prognostic markers; radiological evaluation
(This special issue belongs to the Section Orthopedics)
Interventional and Surgical Treatment of Acute and Chronic Pancreatitis
edited by Chirag Desai
submission deadline 25 Feb 2026 | 5 articles | Viewed by 6175 | Submission Open
Keywords: pancreatitis treatment; endoscopic treatment; pancreatic surgery; Whipple; distal pancreatectomy; islet cell auto trans-plant; total pancreatectomy; TPIAT; laparoscopic treatment of pancreatitis; robotic surgery for pancreatitis
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
New Advances in Keratoplasty
edited by Cristina Bovone
submission deadline 25 Feb 2026 | 3 articles | Viewed by 5670 | Submission Open
Keywords: lamellar keratoplasty; descemet stripping endothelial keratoplasty (DSAEK); descemet membrane endothelial keratoplasty (DMEK); deep anterior lamellar keratoplasty (DALK); keratoconus; corneal dystrophies; bullous keratopathy; anterior segment OCT
(This special issue belongs to the Section Ophthalmology)
Acute Coronary Syndromes: From Diagnosis to Treatment
edited by and Christos Eftychiou
submission deadline 25 Feb 2026 | 2 articles | Viewed by 5321 | Submission Open
Keywords: acute coronary syndrome; diagnosis; biomarkers; interventional cardiology; imaging; pharmacotherapy; patient management; health systems; special populations; clinical trials
(This special issue belongs to the Section Cardiology)
Advances in the Management of Cardiac Amyloidosis and Hypertrophic Cardiomyopathy
edited by Ahmed Abuzaid
submission deadline 25 Feb 2026 | 3 articles | Viewed by 4510 | Submission Open
Keywords: cardiac amyloidosis; hypertrophic cardiomyopathy; left ventricular hypertrophy; non-invasive cardiac imaging; heart failure; clinical manifestations
(This special issue belongs to the Section Cardiology)
New Insights into Cardiorenal Metabolic Syndrome
edited by
submission deadline 25 Feb 2026 | 3 articles | Viewed by 4311 | Submission Open
Keywords: cardiorenal medicine; diabetes; chronic renal failure; heart failure; cardiorenal syndrome; nephrocardiology
(This special issue belongs to the Section Cardiovascular Medicine)
Alzheimer’s Disease and Related Disorders: Recent Advances in Prevention, Diagnosis and Therapy submission deadline 25 Feb 2026 | 2 articles | Viewed by 3101 | Submission Open
Keywords: cognition; prodromal; Alzheimer’ s; Alzheimer; dementia; mild cognitive impairment; mild decline in cognition; disease-modifying; amyloid; tau; neuroinflammation; biomarkers; neuroimaging; PET; PET/CT; PET/MRI
(This special issue belongs to the Section Clinical Neurology)
Recent Advances in Reconstructive Oral and Maxillofacial Surgery submission deadline 25 Feb 2026 | 2 articles | Viewed by 2890 | Submission Open
Keywords: oral surgery; maxillofacial surgery; new technologies; free flap; reconstructive surgery; artificial intelligence
(This special issue belongs to the Section General Surgery)
Clinical Aspects and Outcomes in Contemporary Colorectal Surgery
edited by
submission deadline 25 Feb 2026 | 3 articles | Viewed by 2704 | Submission Open
Keywords: colorectal surgery; colorectal cancer; Crohn’ s disease; ulcerative colitis; coloproctology; minimally invasive surgery
(This special issue belongs to the Section General Surgery)
Obesity Surgery—State of the Art
edited by Anna Casajoana
submission deadline 25 Feb 2026 | 2 articles | Viewed by 2697 | Submission Open
Keywords: obesity; bariatric surgery; metabolic surgery; diabetes mellitus type 2; GLP-1
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
Clinical Research in Palliative Care
edited by Cosimo Chelazzi
submission deadline 25 Feb 2026 | 2 articles | Viewed by 2429 | Submission Open
Keywords: cancer palliative care; total pain; advanced care planning; spiritual care; financial toxicity; cancer-related pain
(This special issue belongs to the Section Clinical Rehabilitation)
Updates in the Orthopedic Management of Foot Disorders: 2nd Edition
edited by and
submission deadline 25 Feb 2026 | 2 articles | Viewed by 2252 | Submission Open
Keywords: foot pathologies; diabetic feet; forefoot deformities; oncology surgery; foot tumors; minimally invasive surgery; percutaneous surgery; foot joint arthroscopy; stress fractures
(This special issue belongs to the Section Orthopedics)
Innovations in Advanced Echocardiography
edited by Rebecca T. Hahn and Alexandros Papachristidis
submission deadline 25 Feb 2026 | 1 articles | Viewed by 1328 | Submission Open
Keywords: advanced echocardiography; ultrafast ultrasound; contrast echocardiography; subharmonic aided pressure estima-tion; artificial intelligence; 3D echocardiography
(This special issue belongs to the Section Cardiology)
Non-Small-Cell Lung Cancer: Screening, Diagnosis and Treatment Options in the AI and Omics Era
edited by Miljana Tanić
submission deadline 25 Feb 2026 | 2 articles | Viewed by 1193 | Submission Open
Keywords: lung cancer; NSCLC; radiomics; digital pathology; electronic health records; tumor profiling; AI; machine learning; deep learning; liquid biopsy; early detection; diagnosis; prognosis; therapy; biomarkers; management
(This special issue belongs to the Section Respiratory Medicine)
Recent Advances in Clinical Pharmacology Based on Pharmacokinetics
edited by , and
submission deadline 25 Feb 2026 | Viewed by 948 | Submission Open
Keywords: PK/PD modeling; dose optimization; clinical decision-making tools; therapeutic drug monitoring; personalized medicine
(This special issue belongs to the Section Pharmacology)
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