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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Diagnosis and Treatment for Hearing Loss: Expert Views

edited by

Robert A. Saadi

and John L. Dornhoffer

submission deadline 25 Sep 2026 | 2 articles | Viewed by 2859 | Submission Open

Keywords: hearing loss; cochlear implants; hearing aid technology; regenerative medicine; diagnostic audiology

(This special issue belongs to the Section Otolaryngology)

Current Advances and Future Perspectives of Sepsis and Septic Shock

edited by Filippo Mearelli and Gianni Biolo

submission deadline 25 Sep 2026 | 2 articles | Viewed by 2489 | Submission Open

Keywords: sepsis; epidemiology; biomarkers; diagnosis; predictive models; prognostication

(This special issue belongs to the Section Emergency Medicine)

Latest Advances in Ocular Surface Diseases

edited by Barbara Burgos-Blasco

submission deadline 25 Sep 2026 | 2 articles | Viewed by 2083 | Submission Open

Keywords: cornea; keratitis; ocular surface disease; dry eye; corneal ulcer; keratoplasty; conjunctival disease

(This special issue belongs to the Section Ophthalmology)

Deep Vein Thrombosis and Pulmonary Embolism: Current Clinical Treatment and Management

edited by Windsor Ting

submission deadline 25 Sep 2026 | 1 articles | Viewed by 1963 | Submission Open

Keywords: deep vein thrombosis; pulmonary embolus; vein stenosis. iliac vein stenosis; May-Thurner syndrome; thoracic outlet syndrome; renal vein stenosis; nutcracker syndrome

(This special issue belongs to the Section Vascular Medicine)

Latest Advances in Minimally Invasive Spine Surgery

edited by Fabian Sommer and

Roger Härtl

submission deadline 25 Sep 2026 | 2 articles | Viewed by 1912 | Submission Open

Keywords: minimally invasive spine surgery (MISS); advances in spine surgery; future directions of MISS; navigation and orientation; intramedullary/extramedullary tumor resections; emerging technologies in MISS (robotics, augmented reality, artificial intelligence, etc.); degenerative spine; patient safety in MISS

(This special issue belongs to the Section Clinical Neurology)

Idiopathic Thrombocytopenic Purpura (ITP) and Thrombotic Thrombocytopenic Purpura (TTP): Pathophysiology, Clinical Practice and Future Developments

edited by María Eva Mingot Castellano

submission deadline 25 Sep 2026 | 2 articles | Viewed by 1629 | Submission Open

Keywords: ITP; TTP; thrombocytopenia; autoimmune; bleeding; thrombosis; caplacizumab; steroids; plasma exchange; infections; thrombopoetin; thrombopoetin analogs; immunosuppressive; immunomodulation; quality of life; fatigue

(This special issue belongs to the Section Hematology)

Corneal Surgery: From Innovation to Clinical Practice

edited by Joanna Wasielica-Poslednik

submission deadline 25 Sep 2026 | 1 articles | Viewed by 1526 | Submission Open

Keywords: keratoplasty; penetrating keratoplasty; DMEK; eye banking; corneal surgery

(This special issue belongs to the Section Ophthalmology)

Emergency Surgery: Recent Advances and Practical Strategies

edited by Avi Benov

submission deadline 25 Sep 2026 | 2 articles | Viewed by 1396 | Submission Open

Keywords: emergency surgery; acute care surgery; trauma; prehospital care; early decision-making; clinical outcomes; risk stratification; real-world evidence; registries

(This special issue belongs to the Section Emergency Medicine)

Tendon and Ligament Injury and Current Strategies for Tendon and Ligament Regeneration

edited by Andrej Čretnik, Bore Bakota and Dejan Blažević

submission deadline 25 Sep 2026 | 1 articles | Viewed by 1133 | Submission Open

Keywords: tendons; ligaments; injuries; tendinopathies; minimally invasive surgery; functional treatment; tissue engineering; novelties

(This special issue belongs to the Section Orthopedics)

Clinical Advances in General and Regional Anesthesia

edited by Luciano Frassanito

submission deadline 25 Sep 2026 | 1 articles | Viewed by 1095 | Submission Open

Keywords: oncoanesthesia; perinatal anesthesia; ventilatory support; hemodynamic monitoring; regional anesthesia

(This special issue belongs to the Section Anesthesiology)

Coronary Intervention: Current Strategies and Future Directions

edited by

Jong-Hwa Ahn

submission deadline 25 Sep 2026 | 2 articles | Viewed by 1049 | Submission Open

Keywords: coronary intervention; percutaneous coronary intervention; complex PCI; intravascular imaging; coronary physiology; antiplatelet therapy; cardiovascular outcomes

(This special issue belongs to the Section Cardiovascular Medicine)

Gastrointestinal Surgery and Pain Management: Contemporary Advances and Clinical Insights

edited by

Dimitrios Giannis

submission deadline 25 Sep 2026 | 1 articles | Viewed by 716 | Submission Open

Keywords: gastrointestinal surgery; postoperative pain; chronic pain; acute pain; perioperative care; pain management; multimodal analgesia; enhanced recovery

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Ocular Microcirculation and Clinical Outcomes in Ophthalmic Diseases

edited by Robert Rejdak and

Małgorzata Latalska

submission deadline 25 Sep 2026 | 1 articles | Viewed by 660 | Submission Open

Keywords: ocular microcirculation; clinical outcomes; diabetic retinopathy; glaucoma; optic nerve diseases; ocular blood flow; ophthalmic diseases; retinal disorders; imaging techniques; hemodynamics

(This special issue belongs to the Section Ophthalmology)

Myeloid-Derived Suppressor and Innate Immune Cells in Hematologic, Malignant and Chronic Diseases

edited by

Helen A. Papadaki

submission deadline 25 Sep 2026 | Viewed by 470 | Submission Open

Keywords: myeloid-derived suppressor cells (MDSCs); macrophages; monocytes; eosinophils; neutrophils; malignancy; cancer; autoimmunity; infection; chronic inflammation; therapeutic target; biomarker; precision medicine; molecular pathways; bone marrow microenvironment

(This special issue belongs to the Section Hematology)

Advances in the Diagnosis and Management of Sarcoidosis

edited by

Carlos Feijoo-Massó

, Pilar Brito-Zerón and Miriam Akasbi Montalvo

submission deadline 25 Sep 2026 | Viewed by 363 | Submission Open

Keywords: sarcoidosis; diagnosis; biomarkers; imaging; immunopathogenesis; biologic therapy; prognosis; interstitial lung disease

(This special issue belongs to the Section Immunology & Rheumatology)

From Heart to Brain: Interdisciplinary Perspectives on Cerebral Infarction

edited by

Laurent Suissa

and Jean-Claude Deharo

submission deadline 25 Sep 2026 | Viewed by 361 | Submission Open

Keywords: ischemic stroke; cardioembolic stroke; atrial fibrillation; heart–brain axis; neurocardiology; post-stroke cardiac dysfunction; stroke prevention; cerebral infarction; cardiac monitoring in stroke; secondary stroke prevention

(This special issue belongs to the Section Clinical Neurology)

Robotic Urologic Surgery: Applications and Prospects

edited by

Guglielmo Mantica

submission deadline 25 Sep 2026 | Viewed by 296 | Submission Open

Keywords: urology; robotic surgery; RAPN; RARP; robotic procedures

(This special issue belongs to the Section General Surgery)

Current Treatment on Urinary Tract Infection

edited by

Biagio Barone

submission deadline 25 Sep 2026 | Viewed by 275 | Submission Open

Keywords: urinary tract infections (UTIs); antibiotic resistance; probiotics and alternative therapies; diagnostic advancements; urinary infection management

(This special issue belongs to the Section Nephrology & Urology)

Innovative Approaches to the Epidemiology, Diagnosis, and Treatment of Systemic Sclerosis

edited by

Antonio-Javier Chamorro

submission deadline 25 Sep 2026 | Viewed by 274 | Submission Open

Keywords: systemic sclerosis; scleroderma; epidemiology; biomarkers; personalized therapy; therapeutic strategies

(This special issue belongs to the Section Clinical Neurology)

Challenges and Clinical Surveillance in Cerebral Aneurysm Management

edited by Joseph Antonios

submission deadline 25 Sep 2026 | Viewed by 238 | Submission Open

Keywords: intracranial aneurysm; cerebral aneurysm surveillance; risk stratification; aneurysm progression; vascular inflammation

(This special issue belongs to the Section Clinical Neurology)

Diagnosis, Treatment and Prognosis of Benign Prostatic Hyperplasia and Prostate Cancer

edited by Christian Wetterauer

submission deadline 25 Sep 2026 | Viewed by 230 | Submission Open

Keywords: benign prostatic hyperplasia; prostate cancer; urology; urological oncology; oncological outcomes; risk stratification; benign prostatic obstruction; minimally invasive techniques; artificial intelligence

(This special issue belongs to the Section Nephrology & Urology)

Lifelong Care in Congenital Heart Disease

edited by

Cristina Ciuca

submission deadline 25 Sep 2026 | Viewed by 223 | Submission Open

Keywords: fetal echocardiography; pediatric cardiology; adults with congenital heart disease (ACHD); transition of care; cardio-obstetrics; heart failure; pregnancy; advanced imaging; echocardiography; cardiovascular risk prevention

(This special issue belongs to the Section Cardiovascular Medicine)

Mitral Valve Stenosis or Aortic Valve Stenosis: Progress from Diagnosis to Treatment

edited by Francesco Melillo

submission deadline 28 Sep 2026 | 3 articles | Viewed by 7920 | Submission Open

Keywords: aortic stenosis; mitral stenosis; TAVI

(This special issue belongs to the Section Cardiology)

Management of Female Pelvic Floor Disorders and Incontinence

edited by Luis López Fando

submission deadline 28 Sep 2026 | 3 articles | Viewed by 2508 | Submission Open

Keywords: pelvic floor disorders; urinary incontinence; pelvic organ prolapse; reconstructive urology; voiding dysfunction; multidisciplinary care; surgical techniques; urodynamics; patient-centered outcomes; digital learning in urology

(This special issue belongs to the Section Nephrology & Urology)

Current Challenges in Oral Surgery and Pathology

edited by

Christian Bacci

submission deadline 28 Sep 2026 | 2 articles | Viewed by 2152 | Submission Open

Keywords: oral medicine; oral pathology; oral surgery; ONJ; MRONJ; BRONJ; laser

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Recent Clinical Perspective in Kidney Transplantation

edited by Nikolina Bašić-Jukić

submission deadline 29 Sep 2026 | 7 articles | Viewed by 6325 | Submission Open

Keywords: kidney transplantation; outcomes; desensitization; xenotransplantation; transplant nephropathology; multiorgan transplantations; post-transplant complications; inequities in transplantation

(This special issue belongs to the Section Nephrology & Urology)

Glaucoma: Diagnosis and Management Insights

edited by

Stamatios Lampsas

and Efthymios Karmiris

submission deadline 29 Sep 2026 | 3 articles | Viewed by 2586 | Submission Open

Keywords: glaucoma; risk factors; progression; novel biomarkers; diagnosis; management

(This special issue belongs to the Section Ophthalmology)

New Insights into Cardiovascular Radiology

edited by Amalia Lupi and

Riccardo Cau

submission deadline 29 Sep 2026 | 3 articles | Viewed by 1826 | Submission Open

Keywords: CMR; tissue characterization; 4Dflow; CCTA; photon counting CT; plaque characterization

(This special issue belongs to the Section Nuclear Medicine & Radiology)

New Advances in Musculoskeletal Physiotherapy: Exercise, Manual Therapy and Invasive Physiotherapy

edited by

Marcos José Navarro-Santana

and Ignacio Cancela-Cilleruelo

submission deadline 30 Sep 2026 | 6 articles | Viewed by 22260 | Submission Open

Keywords: musculoskeletal disorders; exercise therapy; manual therapy; invasive physical therapy; rehabilitation

(This special issue belongs to the Section Orthopedics)

Catheter Ablation of Cardiac Arrhythmias: Current Updates and Perspectives: 2nd Edition

edited by

Shaojie Chen

submission deadline 30 Sep 2026 | 3 articles | Viewed by 7423 | Submission Open

Keywords: ablation; arrhythmia; electrophysiology; atrial fibrillation; atrial flutter; atrial tachycardia; mapping; supraventricular tachycardia; ventricular arrhythmia

(This special issue belongs to the Section Cardiology)

Clinical Updates on Dyslipidemia

edited by

Nathan Wong

submission deadline 30 Sep 2026 | 4 articles | Viewed by 5295 | Submission Open

Keywords: dyslipidemia; cardiovascular disease; prevention; treatment; risk factors

(This special issue belongs to the Section Cardiovascular Medicine)

Artificial Intelligence in Women’s Health and Medicine: Improving Clinical Practice, Diagnosis, Treatment Management and Patient Experiences

edited by

Shivaram Poigai Arunachalam

and Nasibeh Zanjirani Farahani

submission deadline 30 Sep 2026 | 1 articles | Viewed by 4293 | Submission Open

Keywords: women’s health; artificial intelligence; machine learning; personalized medicine; reproductive health; health equity; social determinants of health; mental health; cancer; cardiovascular disease

(This special issue belongs to the Section Epidemiology & Public Health)

Clinical Advances in Hepatology

edited by

Dimitrios S. Karagiannakis

and

Theodoros Androutsakos

submission deadline 30 Sep 2026 | 3 articles | Viewed by 4287 | Submission Open

Keywords: cirrhosis; portal hypertension; non-invasive tests; viral hepatitis; MASLD; HCC

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Modern Oral Surgery and Periodontology: Technological Advances, Innovation, and Clinical Applications

edited by Rafał Wiench and

Wojciech Niemczyk

submission deadline 30 Sep 2026 | 2 articles | Viewed by 1484 | Submission Open

Keywords: oral surgery; periodontology; periodontal regeneration; implant dentistry; peri-implant diseases, guided surgery; biomaterials; platelet concentrates (PRF, PRP); bone regeneration

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Targeted Management of Orofacial Pain: From Pharmacology to Temporomandibular Joint Surgery

edited by

Matteo Val

Luca Guarda-Nardini

and Giulia Ottaviani

submission deadline 30 Sep 2026 | 2 articles | Viewed by 1395 | Submission Open

Keywords: orofacial pain; chronic orofacial pain; neuropathic pain; pharmacological management; temporomandibular joint disorders; degenerative TMJ disease; conservative treatment; surgical management

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Burnout and Anxiety in Clinical and Occupational Contexts: Mental Health, Work-Related Stress, and Vulnerable Populations

edited by

Patricia Catalá

and

Cecilia Peñacoba-Puente

submission deadline 30 Sep 2026 | 1 articles | Viewed by 985 | Submission Open

Keywords: mental health; burnout; anxiety; occupational stress; women’s mental health; perinatal mental health; healthcare professionals; work-related stress; psychosocial factors; clinical interventions

(This special issue belongs to the Section Mental Health)

Interplay of Motility, Microbiota, and Function: New Insights into GI Disorders, IBS, and SIBO

edited by Tsachi Tsadok Perets

submission deadline 30 Sep 2026 | 1 articles | Viewed by 903 | Submission Open

Keywords: gastrointestinal motility; irritable bowel syndrome (IBS); small intestinal bacterial overgrowth (SIBO); gut microbiota; functional gastrointestinal disorders

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Updates and Advances in Aplastic Anemia and Other Bone Marrow Failures

edited by

Alicia Rovo

, Beatrice Drexler and Olaia Naveiras

submission deadline 30 Sep 2026 | Viewed by 481 | Submission Open

Keywords: aplastic anemia; severe aplastic anemia (SAA); bone marrow failures; paroxysmal nocturnal hemoglobinuria (PNH); inherited bone marrow failures

(This special issue belongs to the Section Hematology)

Acute Care Surgery: The Evolution of a Modern Specialty

edited by Mayur Narayan

submission deadline 30 Sep 2026 | Viewed by 373 | Submission Open

Keywords: acute care surgery; emergency surgery; health equity; global surgery; trauma care; surgical workforce; surgical in-novation; decision-making

(This special issue belongs to the Section Emergency Medicine)

Innovative Treatments and Management of Diabetes in Pregnancy

edited by Verónica Perea

submission deadline 30 Sep 2026 | Viewed by 269 | Submission Open

Keywords: diabetes in pregnancy; gestational diabetes mellitus; type 1 diabetes; continuous glucose monitoring; automated insulin delivery; innovative therapies; digital health

(This special issue belongs to the Section Endocrinology & Metabolism)

Update and Emerging Trends in Urological Surgery

edited by Yasmin Abu-Ghanem

submission deadline 30 Sep 2026 | Viewed by 254 | Submission Open

Keywords: urology; urological surgery; precision medicine; biomarkers; minimally invasive surgery; multidisciplinary care

(This special issue belongs to the Section Nephrology & Urology)

Current Concepts in Shoulder Arthroplasty—Degenerative Pathology, Scapular Morphology, Posture and Kinematics, Realignment Procedures, Fracture Reconstruction, and Outcome Measurement

edited by

Stefan Bauer

Allan W. Wang

and

William G. Blakeney

submission deadline 1 Oct 2026 | 3 articles | Viewed by 1877 | Submission Open

Keywords: reverse total shoulder arthroplasty; cuff tear arthropathy; osteoarthritis; proximal humeral fracture sequelae; revision; long-term outcome; implant design; biomechanics

(This special issue belongs to the Section Orthopedics)

Clinical Perspectives in Emerging Infectious Diseases

edited by

Steven Van Lelyveld

submission deadline 4 Oct 2026 | Viewed by 259 | Submission Open

Keywords: emerging infectious diseases; one health; arbovirus disease; avian influenza; hemorrhagic fever; coronavirus diseases; Nipah virus

(This special issue belongs to the Section Infectious Diseases)

Diagnosis and Treatment of Obstetrics and Gynecology Cancers

edited by

Gaspare Cucinella

submission deadline 5 Oct 2026 | 4 articles | Viewed by 12533 | Submission Open

Keywords: gynecological cancers; endometrial cancer; ovarian cancer; cervical cancer; vulvar cancer; vaginal cancer; breast cancer; surgery; radio-therapy; systemic treatment; immunotherapy; sentinel lymph node biopsy; minimally invasive surgery; fertility preservation; gestational trophoblastic disease

(This special issue belongs to the Section Obstetrics & Gynecology)

New Insights into Pediatric Otolaryngology: From Diagnosis to Minimally Invasive Therapies

edited by

Mariaconsiglia Santantonio

and

Luisa Bellussi

submission deadline 5 Oct 2026 | 3 articles | Viewed by 2541 | Submission Open

Keywords: pediatric otolaryngology; minimally invasive; early diagnosis; olfactory disorders; pediatric rhinology; pediatric airway; pediatric ENT; pediatric sleep disorders; pediatric diagnosis

(This special issue belongs to the Section Clinical Pediatrics)

Thoracic Radiochemoimmunotherapy for Non-Small Cell Lung Cancer (NSCLC): Evolving Techniques and Clinical Applications

edited by

Franz Zehentmayr

submission deadline 5 Oct 2026 | 1 articles | Viewed by 1344 | Submission Open

Keywords: radiotherapy; radiology; oncology; non-small cell lung cancer; real-world data; immunotherapy; radiation dose escalation

(This special issue belongs to the Section Oncology)

Current Progress and Future Directions in Orthodontics and Periodontology

edited by

Ligia Vaida

and

Ionut Luchian

submission deadline 5 Oct 2026 | Viewed by 372 | Submission Open

Keywords: orthodontics; periodontology; interdisciplinary treatment; orthodontic tooth movement; periodontal phenotype; digital dentistry; regenerative therapy; clinical outcomes; treatment planning; future perspectives of interdisciplinarity

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Neuropathic Pain: From Prevention to Diagnosis and Management

edited by Enrico Martin

submission deadline 10 Oct 2026 | 2 articles | Viewed by 5814 | Submission Open

Keywords: neuropathic pain; clinical research; TMR; RPNI; preclinical studies; QoL; PROMS; translational medicine; pain mechanisms

(This special issue belongs to the Section Clinical Neurology)

New Insights into Clinical Application of Embolization Techniques

edited by

Bedros Taslakian

and Yan Epelboym

submission deadline 10 Oct 2026 | 3 articles | Viewed by 4270 | Submission Open

Keywords: embolization; interventional radiology; musculoskeletal embolization; uterine artery embolization; prostate artery embolization; vascular malformations; catheter-directed therapy

(This special issue belongs to the Section Vascular Medicine)

Current Trends and Future Challenges in Coronary Artery Disease

edited by Federica Agnello

submission deadline 10 Oct 2026 | 2 articles | Viewed by 1737 | Submission Open

Keywords: coronary artery disease; cardiovascular prevention; coronary computed tomography angiography (CCTA); CT-derived fractional flow reserve (FFR-CT); intracoronary imaging; residual risk; functional assessment; artificial intelligence in cardiology; percutaneous coronary intervention

(This special issue belongs to the Section Cardiology)

Displaying special issue 151-200 on page 4 of 30.

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