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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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State-of-the-Art Research on Thoracic Surgery

edited by

Russell Seth Martins

submission deadline 20 Nov 2025 | 1 articles | Viewed by 1121 | Submission Open

Keywords: 3D imaging; surgical process optimization; robotic surgery; immunotherapy and targeted therapy; novel cancer detection methods; personalized treatment

(This special issue belongs to the Section General Surgery)

Targeted Diagnosis and Treatment of Shoulder and Elbow Disease: 2nd Edition

edited by

Teresa Paolucci

and

Massimiliano Mangone

submission deadline 20 Nov 2025 | 1 articles | Viewed by 1050 | Submission Open

Keywords: anterolateral deltoid split; joint pain; axillary nerve injury; rotator cuff injuries; shoulder arthroplasty; shoulder impingement syndrome; proximal humeral fracture; rehabilitation; exercise; physiotherapy; rehabilitative relapses

(This special issue belongs to the Section Orthopedics)

Research Progress in Pediatric Endocrinology

edited by

Federico Baronio

submission deadline 20 Nov 2025 | 1 articles | Viewed by 1024 | Submission Open

Keywords: pediatric endocrinology; rare endocrine disorders; precision medicine; congenital adrenal hyperplasia (CAH); short stature genetics; severe childhood obesity; glp-1 receptor agonists; endocrine disruptors; artificial intelligence (AI) in endocrinology; newborn screening

(This special issue belongs to the Section Clinical Pediatrics)

Acute Ischemic Stroke Management Strategies

edited by

Marta Iacobucci

submission deadline 20 Nov 2025 | 1 articles | Viewed by 981 | Submission Open

Keywords: mechanical thrombectomy; leptomeningeal collateral circulation; neuroprotection; reperfusion injury; ischemic penumbra

(This special issue belongs to the Section Clinical Neurology)

Skin Wound Healing: Clinical Updates and Perspectives

edited by

András Bánvölgyi

and

Norbert Kiss

submission deadline 20 Nov 2025 | 1 articles | Viewed by 793 | Submission Open

Keywords: dermatology; wound care; diagnosis; biomaterials; negative pressure wound therapy

(This special issue belongs to the Section Dermatology)

Clinical Insights in Maternal–Fetal Medicine

edited by Moti Gulersen

submission deadline 20 Nov 2025 | 1 articles | Viewed by 786 | Submission Open

Keywords: preterm birth; antenatal corticosteroids; preeclampsia; ultrasound; fetal growth; congenital anomalies; infection; maternal morbidity; diabetes; multiple gestation

(This special issue belongs to the Section Obstetrics & Gynecology)

Diagnosis and Treatment of Ocular Surface Diseases

edited by

Stuti Misra

and

Sònia Travé-Huarte

submission deadline 20 Nov 2025 | 1 articles | Viewed by 749 | Submission Open

Keywords: dry eye disease; ocular surface; anterior segment imaging; biomarkers; artificial intelligence; diagnostic tools; novel therapeutic agents; anterior eye care

(This special issue belongs to the Section Ophthalmology)

Low Back Pain: Clinical Treatment and Management

edited by

Raffaello Pellegrino

and

Angelo Di Iorio

submission deadline 20 Nov 2025 | 1 articles | Viewed by 743 | Submission Open

Keywords: exercise; rehabilitation; weight loss; telerehabilitation; pain; physical therapy; treatment; conservative treatment; intervertebral disk displacement; low back pain; sciatica

(This special issue belongs to the Section Clinical Neurology)

Clinical Procedures for Diagnosis and Treatment of Cardiovascular Diseases

edited by Ahmad Jabri, Mohammad Alqarqaz, Qais Radaideh and Ahmad Al-Abdouh

submission deadline 20 Nov 2025 | 1 articles | Viewed by 538 | Submission Open

Keywords: cardiovascular disease; diagnostic imaging; minimally invasive procedures; precision medicine; artificial intelligence; interventional cardiology; surgical innovations; patient outcomes; preventive cardiology

(This special issue belongs to the Section Cardiovascular Medicine)

Challenges and Future Trends in Bariatric Surgery

edited by Maurizio L. de Luca and Amanda Belluzzi

submission deadline 20 Nov 2025 | Viewed by 405 | Submission Open

Keywords: metabolic and bariatric surgery; SADI-S; LSG; RYGB; SASI; OAGB; complications after MBS; long-term outcomes; malnutrition

(This special issue belongs to the Section General Surgery)

Clinical Therapeutic and Management Strategies of Epilepsy—Social and Neuropsychological Aspects

edited by

Hideaki Kanemura

submission deadline 20 Nov 2025 | Viewed by 326 | Submission Open

Keywords: quality of life (QOL); cognition; behavior; stigma; seizure severity; interictal epileptiform discharge (IED); social

(This special issue belongs to the Section Clinical Neurology)

New Therapies for Diabetic Foot Ulcer Management

edited by

Irene Sanz-Corbalan

and

Raúl J. Molines Barroso

submission deadline 20 Nov 2025 | Viewed by 273 | Submission Open

Keywords: diabetic foot disease; diabetic foot ulcers; wound healing; biomarkers; telemedicine; artificial intelligence; preven-tive strategies; advanced therapies; amputation prevention; diabetes complications; novel treatments

(This special issue belongs to the Section Endocrinology & Metabolism)

Minimally Invasive Techniques in Digestive Pathologies

edited by

Octavian Andronic

submission deadline 20 Nov 2025 | Viewed by 218 | Submission Open

Keywords: minimally invasive surgery; laparoscopic techniques; robotic surgery; endoscopic interventions; hybrid surgical approaches; digestive oncology; AI in surgery; surgical innovation; gastrointestinal disorders

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Cardiac MRI: Current Techniques and Future Directions

edited by

Édouard Gerbaud

submission deadline 20 Nov 2025 | Viewed by 197 | Submission Open

Keywords: cardiac magnetic resonance imaging; technology; sequences; applications; acute coronary syndrome; intravascular imaging; CT-scanner

(This special issue belongs to the Section Cardiology)

Clinical Research in Management of Corneal Diseases

edited by Massimo Busin and Angeli Christy Yu

submission deadline 20 Nov 2025 | Viewed by 172 | Submission Open

Keywords: corneal surgery; corneal transplant; lamellar keratoplasty; deep anterior lamellar keratoplasty; descemet membrane endothelial keratoplasty; descemet stripping automated endothelial keratoplasty; corneal neurotization

(This special issue belongs to the Section Ophthalmology)

Diagnosis and Treatment of Scoliosis and Spinal Deformity

edited by Anna Rienmueller and Kenny Yat Hong Kwan

submission deadline 20 Nov 2025 | Viewed by 161 | Submission Open

Keywords: scoliosis; spinal deformity; adolescent idiopathic scoliosis (AIS); early onset scoliosis (EOS); neuromuscular scoliosis; adult spinal deformity (ASD); operative treatment; spinal fusion; neuromonitoring in scoliosis and deformity surgery; perioperative risk factors; conservative treatment; bracing therapy; physiotherapy scoliosis-specific exercises (PSSE) and Schroth therapy; spinal biomechanics; scoliosis imaging; low-dose radiation imaging; artificial intelligence in scoliosis; 3D modelling in spinal deformity including surgical planning; predictive modelling in scoliosis progression; biomechanics of spinal curvature; growth modulation; patient-reported outcomes in scoliosis treatment

(This special issue belongs to the Section Orthopedics)

High-Risk Neuroblastoma and Rhabdoid Tumors: New Clinical Insights and Challenges (Second Edition)

edited by

Rupert Handgretinger

and Johannes Hubertus Schulte

submission deadline 20 Nov 2025 | Viewed by 138 | Submission Open

Keywords: neuroblastoma; rhabdoid tumor; autologous stem cell transplantation; allogeneic stem cell transplantation immunotherapy; anti-GD2 antibody; targeted therapy; CAR T-cells

(This special issue belongs to the Section Oncology)

Effect of Long-Term Insomnia on Mental Health—2nd Edition

edited by

Aleksandra Rogowska

submission deadline 21 Nov 2025 | 1 articles | Viewed by 5435 | Submission Open

Keywords: anxiety; alcohol and substance use disorders; behavioral addiction; burnout; cognitive dysfunction; depression; eating disorders; gaming addiction; problematic internet/social media use; insomnia; long-term insomnia; mood disorders; post-traumatic stress disorder; stress

(This special issue belongs to the Section Mental Health)

Research Advances in Coagulation Disorders

edited by Alberto Maino

submission deadline 21 Nov 2025 | Viewed by 156 | Submission Open

Keywords: coagulation; bleeding disorders; thrombosis; hemophilia; clotting disorders; hematology

(This special issue belongs to the Section Hematology)

Clinical Features and Management of Psychosis

edited by

Maria Margariti

George Konstantakopoulos

and Michael Hadjulis

submission deadline 23 Nov 2025 | 4 articles | Viewed by 6609 | Submission Open

Keywords: psychosis; clinical features of psychosis; diagnosis of psychosis; schizophrenia; psychotic depression; affective disorder with psychotic features; psychosis in substance use disorders; psychosis in neurological disorders; psychosis in medical conditions; management of psychosis; treatment of psychosis

(This special issue belongs to the Section Mental Health)

Clinical Management of Type 1 Diabetes

edited by Carmen Quirós

submission deadline 25 Nov 2025 | 6 articles | Viewed by 27717 | Submission Open

Keywords: type 1 diabetes; continuous glucose monitoring; hybrid closed loop; hypoglycemia; physical activity; new onset type 1 diabetes; pre-stage 3 type 1 diabetes; smart insulin pens

(This special issue belongs to the Section Endocrinology & Metabolism)

The “Orthogeriatric Fracture Syndrome”—Issues and Perspectives

edited by

Johannes Dominik Bastian

submission deadline 25 Nov 2025 | 17 articles | Viewed by 25625 | Submission Open

Keywords: geriatric trauma; fragility fracture; orthogeriatric; co-management; assessment; integrated care; osteoporosis; sarcopenia; frailty; gait disturbance; fall; rehabilitation; prehabilitation; prevention; ehealth; digitalization

(This special issue belongs to the Section Orthopedics)

Perinatal Mental Health Management

edited by

Sigita Lesinskienë

submission deadline 25 Nov 2025 | 5 articles | Viewed by 17709 | Submission Open

Keywords: perinatal mental health; child mental health; problem behavior; cognitive development therapy; hyperactivity

(This special issue belongs to the Section Mental Health)

Neurovascular Diseases: Clinical Advances and Challenges

edited by

Roberto Colasanti

, Silky Chotai, Alessandro Di Rienzo and Joham Choque-Velasquez

submission deadline 25 Nov 2025 | 10 articles | Viewed by 16275 | Submission Open

Keywords: neurovascular diseases; ischemic stroke; hemorrhagic stroke; aneurysms; vascular malformations; diagnostic imaging; minimally invasive approaches; surgical techniques; endovascular interventions; treatment algorithms

(This special issue belongs to the Section Clinical Neurology)

Clinical Pharmacology: Adverse Drug Reactions

edited by

Andrej Belančić

and Ivana Mudnić

submission deadline 25 Nov 2025 | 5 articles | Viewed by 14194 | Submission Open

Keywords: pharmacology; adverse drug reactions; drug interactions; pharmacovigilance; drug safety

(This special issue belongs to the Section Pharmacology)

Glomerulonephritis: Current Diagnosis, Treatment and Future Options

edited by Ana I. Ávila and

Montserrat M. Díaz-Encarnación

submission deadline 25 Nov 2025 | 3 articles | Viewed by 11869 | Submission Open

Keywords: glomerulonephritis; diagnosis; management; drug therapies; treatment

(This special issue belongs to the Section Nephrology & Urology)

Ventilation in Critical Care Medicine: 2nd Edition

edited by Gianluca Zani

submission deadline 25 Nov 2025 | 1 articles | Viewed by 11352 | Submission Open

Keywords: invasive ventilation; non-invasive ventilation; acute respiratory failure; best PEEP; respiratory weaning; respiratory mechanics; ventilation and perfusion; personalized ventilation

(This special issue belongs to the Section Intensive Care)

Challenges in Diagnosis and Treatment of Gynecological Malignancies in Young Adults

edited by

Oraianthi Fiste

, Dimitrios Haidopoulos and

Michalis Liontos

submission deadline 25 Nov 2025 | 4 articles | Viewed by 9818 | Submission Open

Keywords: gynecological cancers; young adults; young women; fertility; personalized care

(This special issue belongs to the Section Obstetrics & Gynecology)

Gynecological Cancers—Surgical Management, Prognosis, and Quality of Life: 2nd Edition

edited by

Valentina Elisabetta Bounous

submission deadline 25 Nov 2025 | 5 articles | Viewed by 7907 | Submission Open

Keywords: gynecological cancers; endometrial cancer; ovarian cancer; cervical cancer; vulvar cancer; vaginal cancer; breast cancer; surgery; radiotherapy; systemic treatment; quality of life

(This special issue belongs to the Section Obstetrics & Gynecology)

Recent Advances in Spine Tumor Diagnosis and Treatment

edited by Jae Hwan Cho

submission deadline 25 Nov 2025 | 8 articles | Viewed by 7719 | Submission Open

Keywords: spine tumor; spinal metastasis; pathologic fracture; cord compression; separation surgery; radiotherapy; interdisciplinary collaboration; surgeon’ s role; medical oncologist; radiologic oncologist; psychological aspects; pain management; innovative approaches; patient outcomes; diagnostic advancements

(This special issue belongs to the Section Clinical Neurology)

Weaning from Non-Invasive Mechanical Ventilation Approaches (NIV-NHF): Insights on How, When and Where

edited by

Antonio Matías Esquìnas

submission deadline 25 Nov 2025 | 2 articles | Viewed by 7696 | Submission Open

Keywords: non-invasive positive pressure ventilation (NIPPV); nasal high flow oxygen; respiratory failure; intensive care units; pneumology wards; non-invasive mechanical ventilation approaches (NIV nasal high flow)

(This special issue belongs to the Section Intensive Care)

Endometriosis: Clinical Challenges and Prognosis

edited by

Francisco Artacho-Cordon

submission deadline 25 Nov 2025 | 4 articles | Viewed by 7274 | Submission Open

Keywords: endometriosis; therapy; rehabilitation; psychology; diagnostics; ultrasound imaging; metabolomics; prognosis

(This special issue belongs to the Section Obstetrics & Gynecology)

Chronic Lung Conditions: Integrative Approaches to Long-Term Care

edited by

Antigona Carmen Trofor

submission deadline 25 Nov 2025 | 4 articles | Viewed by 7178 | Submission Open

Keywords: chronic lung conditions: chronic non-infectious lung disease and post-respiratory infectious syndromes; including TB sequelae; TB MDR; post-COVID-19; and bronchiectasis; long-term care; integrative approach; multidisciplinary; multimorbidity; outcomes

(This special issue belongs to the Section Respiratory Medicine)

Cystic Fibrosis: Novel Strategies of Diagnosis and Treatments

edited by

Michal Gur

and

Lea Bentur

submission deadline 25 Nov 2025 | 6 articles | Viewed by 7066 | Submission Open

Keywords: cystic fibrosis; CFTR modulators; stop mutations; gene therapy; mRNA therapy; novel therapies; rare pathogens

(This special issue belongs to the Section Respiratory Medicine)

A Multi-Faceted Approach to Urinary Incontinence and Other Pelvic Floor Dysfunction—from Prevention to Therapy

edited by

Agnieszka Mazur-Bialy

submission deadline 25 Nov 2025 | 3 articles | Viewed by 6840 | Submission Open

Keywords: urinary incontinence; pelvic floor dysfunction; urinary and fecal incontinence; pelvic organs prolapse; pelvic pain; pelvic floor disorders

(This special issue belongs to the Section Nephrology & Urology)

Cardiothoracic Surgery and Enhanced Recovery: Recent Advances and Perspectives

edited by Edris A.F. Mahtab

submission deadline 25 Nov 2025 | 3 articles | Viewed by 6455 | Submission Open

Keywords: coronary artery bypass surgery; valve repair/replacement; minimally invasive cardiac procedures; aortic dissection repair; thoracic aortic aneurysm surgery; lung transplantation; ventricular assist devices; esophagectomy; lung surgery; heart transplantation; use of XR and AI in Enhanced recovery

(This special issue belongs to the Section General Surgery)

Clinical Diagnosis and Management of Vestibular Disorders

edited by

Sinisa Maslovara

, Mario Habek and

Andro Košec

submission deadline 25 Nov 2025 | 6 articles | Viewed by 6366 | Submission Open

Keywords: vertigo; dizziness; epidemiology; genetics; diagnostics; management

(This special issue belongs to the Section Otolaryngology)

Clinical Utility of Optical Coherence Tomography in Ophthalmology: 2nd Edition

edited by

Jose Ignacio Fernandez-Vigo

submission deadline 25 Nov 2025 | 4 articles | Viewed by 5837 | Submission Open

Keywords: optical coherence tomography; ophthalmology; intraoperative OCT; en face OCT; wide-field OCT; retinal diseases; glaucoma; cornea; strabismus; cataract

(This special issue belongs to the Section Ophthalmology)

Advances in Dry Eye Disease Treatment: 2nd Edition

edited by

Piera Versura

and

Murat Dogru

submission deadline 25 Nov 2025 | 3 articles | Viewed by 5619 | Submission Open

Keywords: dry eye disease; meibomian gland; tear substitutes; corticosteroids; cyclosporin; antibiotics; non-steroid anti-inflammatory drugs; biological tear substitutes; nutrients; pulsed light

(This special issue belongs to the Section Ophthalmology)

New Perspectives in Lumbar Spine Surgery: Treatment and Management

edited by

Giuseppe La Rocca

submission deadline 25 Nov 2025 | 4 articles | Viewed by 5205 | Submission Open

Keywords: lumbar surgery; spine surgery; minimally invasive techniques; advanced imaging; surgical innovations; patient outcomes; evidence-based practices; postoperative care; rehabilitation strategies; surgical management

(This special issue belongs to the Section Orthopedics)

Advanced Techniques for the Treatment of Complex Coronary Artery Disease: 2nd Edition

edited by Simone Calcagno

submission deadline 25 Nov 2025 | 3 articles | Viewed by 4991 | Submission Open

Keywords: coronary calcified lesion; IVUS; OCT; intravascular lithotripsy; bifurcation coronary lesions; left main; chronic total occlusions; multivessel disease; STEMI; NSTEMI

(This special issue belongs to the Section Cardiovascular Medicine)

Research and Applications in Clinical Pharmacy Based on Pharmacokinetics and Pharmacogenetics

edited by

Marta Miarons

submission deadline 25 Nov 2025 | 3 articles | Viewed by 4797 | Submission Open

Keywords: pharmacokinetics; clinical pharmacy; personalized medicine; drug therapy management; therapeutic drug monitoring

(This special issue belongs to the Section Pharmacology)

Novel Insights into the Diagnosis and Management of Inflammatory Bowel Disease (IBD)

edited by

Alina Ioana Tantau

submission deadline 25 Nov 2025 | 4 articles | Viewed by 3408 | Submission Open

Keywords: inflammatory bowel disease; non-invasive biomarkers; abdominal ultrasonography; colonoscopy; biologic therapy; small molecules; mucosal healing; brain-gut axis; dysbiosis; colorectal dysplasia

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Assessing Strategies and Challenges in Heart Failure: An Update

edited by

Shiro Hoshida

submission deadline 25 Nov 2025 | 2 articles | Viewed by 3208 | Submission Open

Keywords: cardiac MR; coronary microvascular dysfunction; diagnosis; endothelial function; heart failure; myocardial metabolism; prognosis

(This special issue belongs to the Section Cardiology)

Recent Developments and Emerging Trends in Aortic Surgery

edited by Daniele Linardi

submission deadline 25 Nov 2025 | 4 articles | Viewed by 3079 | Submission Open

Keywords: aortic aneurysm; aortic dissection; endovascular repair; minimally invasive approaches; thoracic aorta; abdominal aorta; aortic valve-sparing surgery; aortic stent grafts

(This special issue belongs to the Section Vascular Medicine)

Recent Advances in Intracranial Aneurysm Treatment

edited by Victor Volovici

submission deadline 25 Nov 2025 | 2 articles | Viewed by 3076 | Submission Open

Keywords: intracranial aneurysm; cerebrovascular disease; microneurosurgery; endovascular treatment; subarachnoid hemorrhage

(This special issue belongs to the Section Clinical Neurology)

Thoracic Surgery: Recent Developments and Future Challenges

edited by

Marco Andolfi

and Lucio Cagini

submission deadline 25 Nov 2025 | 1 articles | Viewed by 2685 | Submission Open

Keywords: VATS; RATS; ERAS; sublobar resection; minimally invasive thoracic surgery; target therapy; nodule localization

(This special issue belongs to the Section Respiratory Medicine)

Recent Developments and Emerging Trends of Echocardiography in Cardiac Disease

edited by Petri Gudmundsson

submission deadline 25 Nov 2025 | 2 articles | Viewed by 2480 | Submission Open

Keywords: echocardiography development; artificial intelligence (AI) integration; real-time 3D and 4D imaging; portable and handheld devices; contrast-enhanced imaging; tissue characterization; integration with other modalities; quantitative analysis; tele-echocardiography

(This special issue belongs to the Section Cardiology)

Vascular Surgery: Current Advances and Future Directions

edited by Giovanni Coppi

submission deadline 25 Nov 2025 | 2 articles | Viewed by 2382 | Submission Open

Keywords: stroke; carotid artery stenosis; carotid artery stenting; carotid endarterectomy; occlusion

(This special issue belongs to the Section General Surgery)

Clinical Highlights in Uveal Melanoma

edited by Tomasz Chorągiewicz and

Joanna Dolar-Szczasny

submission deadline 25 Nov 2025 | 1 articles | Viewed by 1897 | Submission Open

Keywords: choroidal melanoma; uveal melanoma; radiotherapy; enucleation; brachytherapy

(This special issue belongs to the Section Ophthalmology)

Displaying special issue 51-100 on page 2 of 30.

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