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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Helicobacter pylori-Associated Intestinal Diseases and Beyond submission deadline 25 Feb 2026 | 1 articles | Viewed by 923 | Submission Open
Keywords: IBD; Hp; stomach; celiac disease; diverticulosis; diverticulitis
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Hospital-Acquired Infections: Evolving Threats and Epidemiological Insights
edited by
submission deadline 25 Feb 2026 | 1 articles | Viewed by 725 | Submission Open
Keywords: hospital-acquired infections; healthcare-associated infections; antimicrobial resistance; multidrug-resistant organisms (MDRO); infection prevention and control; outbreak investigation; patient safety; healthcare epidemiology
(This special issue belongs to the Section Infectious Diseases)
Clinical Advances of Retinal and Vitreous Diseases: Current Status and Prospect
edited by Lorenzo De Angelis, Francesco Barca and Stanislao Rizzo
submission deadline 25 Feb 2026 | 1 articles | Viewed by 428 | Submission Open
Keywords: vitreoretinal surgery; retinal multimodal imaging; gene therapy; retinal diseases; age-related macular degeneration; vascular retinal disease; imaging technologies in ophthalmology
(This special issue belongs to the Section Ophthalmology)
Evidence-Based Physiotherapy: Prospects and Challenges
edited by Roman Nowobilski and
submission deadline 25 Feb 2026 | Viewed by 231 | Submission Open
Keywords: evidence-based practice; physiotherapy; critique; certainty of evidence; clinical practice guidelines; implementa-tion; clinical settings; clinical practice; clinical processing
(This special issue belongs to the Section Clinical Rehabilitation)
Advancing Clinical Medicine Through Artificial Intelligence (AI) and Digital Technology: 2nd Edition submission deadline 25 Feb 2026 | Viewed by 227 | Submission Open
Keywords: artificial intelligence; clinical medicine; medical imaging; precision medicine; clinical decision support systems; patient care; healthcare practices; early disease detection; patient outcomes
(This special issue belongs to the Section Intensive Care)
Clinical Research Progress in Diabetes and Cardiovascular Diseases
edited by
submission deadline 25 Feb 2026 | Viewed by 147 | Submission Open
Keywords: diabetes; cardiovascular diseases; risk factor; vascular function; diagnosis; treatment
(This special issue belongs to the Section Cardiovascular Medicine)
Application of Echocardiography in Clinical Practice
edited by
submission deadline 25 Feb 2026 | Viewed by 144 | Submission Open
Keywords: echocardiography; three-dimensional imaging; mechanical imaging; strain; artificial intelligence; interventional echocardiography; POCUS; hand-held echocardiography; cancer therapy and cardiotoxicity
(This special issue belongs to the Section Cardiovascular Medicine)
Plastic and Reconstructive Surgery: Clinical Advances and Future Opportunities
edited by Rami S Kantar
submission deadline 25 Feb 2026 | Viewed by 122 | Submission Open
Keywords: plastic surgery; reconstructive surgery; cleft lips; palates; post-traumatic reconstruction; facial transplantation; craniofacial surgery; cleft surgery
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
Current Advances and Future Perspectives of Sepsis and Septic Shock
edited by Filippo Mearelli and Gianni Biolo
submission deadline 25 Feb 2026 | Viewed by 110 | Submission Open
Keywords: sepsis; epidemiology; biomarkers; diagnosis; predictive models; prognostication
(This special issue belongs to the Section Emergency Medicine)
Allergic and Eosinophilic Diseases: Diagnosis, Treatment and Management (Second Edition)
edited by Aikaterini Detoraki
submission deadline 25 Feb 2026 | Viewed by 109 | Submission Open
Keywords: allergy; eosinophilic diseases; immunology; clinical immunology; asthma; diagnosis; treatment; management
(This special issue belongs to the Section Immunology & Rheumatology)
Segmentectomy and Lobectomy in Early-Stage Lung Cancer Management
edited by Yujin Kudo
submission deadline 25 Feb 2026 | Viewed by 106 | Submission Open
Keywords: lung cancer; segmentectomy; lobectomy; thoracic surgery; early-stage NSCLC; oncologic outcomes; pulmonary function; surgical planning
(This special issue belongs to the Section Respiratory Medicine)
Spinal Surgery: Recent Advances and Future Perspectives submission deadline 25 Feb 2026 | Viewed by 103 | Submission Open
Keywords: spine surgery; diagnostic technology; AI; images; biomarkers; genetics; robotic surgery; minimum invasive surgery; pain control; VR
(This special issue belongs to the Section Orthopedics)
Clinical Updates of Diagnosis and Treatment in Chronic Kidney Disease (CKD)
edited by , Carmen Mora-Fernández and
submission deadline 25 Feb 2026 | Viewed by 102 | Submission Open
Keywords: CKD; CKD progression; biomarkers; disease-modifying treatments; diabetic kidney disease; cardiorenal disease; glomerunephritis; genetic kidney diseases
(This special issue belongs to the Section Nephrology & Urology)
Clinical Update on the Diagnosis and Treatment of Heart Failure
edited by Giulia Nardi and Alessio Mattesini
submission deadline 26 Feb 2026 | 5 articles | Viewed by 11986 | Submission Open
Keywords: ejection fraction; acute heart failure; multidisciplinary management; right heart failure; left ventricle remodeling systems; HF percutaneous treatment; pharmacotherapy; HF prevention; cardiomyopathies
(This special issue belongs to the Section Cardiovascular Medicine)
Advances in Arrhythmia Diagnosis and Management
edited by Zoltán Csanádi
submission deadline 26 Feb 2026 | 7 articles | Viewed by 7986 | Submission Open
Keywords: catheter ablation; atrial fibrillation; ventricular tachycardia; conduction system pacing; cardiac resynchronization; sudden cardiac death
(This special issue belongs to the Section Cardiology)
Pancreatic Cancer: Novel Strategies of Diagnosis and Treatment submission deadline 26 Feb 2026 | 2 articles | Viewed by 2326 | Submission Open
Keywords: pancreatic cancer; chronic pancreatitis; pancreatic intraepithelial neoplasia; gastroenterology; clinical innovative diagnostic; clinical treatment strategies
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Orthodontics: State of the Art and Perspectives submission deadline 27 Feb 2026 | 9 articles | Viewed by 11917 | Submission Open
Keywords: orthodontics; digital orthodontics; intraoral scanners; facial scanners; treatment planning; interdisciplinary treatment; orthodontic implants
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Unraveling Myopia: Current Science, Clinical Impact, and Future Horizons
edited by Neeraj K Singh and Pablo De Gracia
submission deadline 27 Feb 2026 | 2 articles | Viewed by 1220 | Submission Open
Keywords: accommodation; contact lenses; ophthalmic lenses; myopia progression; epidemiology; myopia control interventions; pharmaceutical treatments; environmental and behavioral risk factors; imaging innovations in myopia
(This special issue belongs to the Section Ophthalmology)
Harnessing Photobiomodulation Light for Therapeutic or Prevention of Human Diseases
edited by
submission deadline 28 Feb 2026 | 6 articles | Viewed by 24088 | Submission Open
Keywords: neurorehabilitation; supportive care for cancer; reproductive health; dental and oral diseases; viral and bacterial diseases; wound care; dermatology; sports rehabilitation; bone and musculoskeletal diseases; PBM mechanism; ophthalmology; stem cells and regenerative medicine; pain and addiction management; PBM-tissue interaction
Advances in Child Neurology submission deadline 28 Feb 2026 | 6 articles | Viewed by 16340 | Submission Open
Keywords: pediatric neurological disorders; pediatric sleep disorders; pediatric epilepsy; autoimmune encephalitis; pediatric acute-onset neuropsychiatric syndrome (PANS); pediatric headaches; RASopathies; neurogenetic disorders; developmental coordination disorder (DCD); pedaitric neurological rehabilitation; AI application for diagnosis and therapeutic management of pediatric neurological diseases
(This special issue belongs to the Section Clinical Pediatrics)
Headache Disorders: New Advances in Management and Treatment Strategies: 2nd Edition submission deadline 28 Feb 2026 | 1 articles | Viewed by 1894 | Submission Open
Keywords: headache; migraine; cluster headache; tension-type headache; post-traumatic headache; calcitonin gene-related peptide; monoclonal antibodies; preventive therapy; acute treatment; pathophysiology; neuromodulation; pain management; drug development; gepants; ditan
(This special issue belongs to the Section Clinical Neurology)
Clinical Updates in Cardiovascular Computed Tomography (CT)
edited by
submission deadline 28 Feb 2026 | 1 articles | Viewed by 1111 | Submission Open
Keywords: cardiovascular CT; coronary CTA; plaque imaging; artificial intelligence; low-dose imaging; structural heart disease; cardiac imaging; high-risk plaque; atherosclerosis; coronary artery disease; valve calcification; thrombus detection
(This special issue belongs to the Section Cardiovascular Medicine)
Tumor Microenvironment—Current Status and Therapeutic Targets
edited by
submission deadline 28 Feb 2026 | 1 articles | Viewed by 1081 | Submission Open
Keywords: tumor microenvironment (TME); cancer immunology; immune checkpoint inhibitors; cancer biology; targeted therapies
(This special issue belongs to the Section Oncology)
New Insights into Head and Neck Surgery—2nd Edition submission deadline 28 Feb 2026 | 1 articles | Viewed by 923 | Submission Open
Keywords: otorhinolaryngology; head and neck surgery; ear surgery; sinonasal surgery; skull base surgery; salivary gland surgery; thyroid gland surgery; head and neck cancer surgery
(This special issue belongs to the Section General Surgery)
Neuromuscular Diseases and Musculoskeletal Disorders
edited by
submission deadline 28 Feb 2026 | 1 articles | Viewed by 751 | Submission Open
Keywords: neuromuscular diseases; osteoporosis; fractures; muscle weakness; muscle intolerance; shoulder dysfunction; myopathy; physiotherapy; rehabilitation
(This special issue belongs to the Section Clinical Neurology)
Clinical Therapeutic Advances of Mitral Regurgitation
edited by Angelo Squeri
submission deadline 28 Feb 2026 | 2 articles | Viewed by 714 | Submission Open
Keywords: mitral regurgitation; mitral valve prolapse; cardiovascular interventions; heart surgery; echocardiography; mag-netic resonance imaging; computed tomography
(This special issue belongs to the Section Cardiovascular Medicine)
Towards a New Paradigm: Opioid-Free and Opioid-Sparing Strategies in Modern Anesthesia submission deadline 28 Feb 2026 | 2 articles | Viewed by 603 | Submission Open
Keywords: opioid-free anesthesia; opioid-sparing strategies; multimodal analgesia; regional anesthesia; non-opioid analgesics; enhanced recovery after surgery (ERAS); perioperative pain management; postoperative analgesia; anesthesia innovation; chronic pain prevention; patient-centered anesthesia; clinical outcomes in anesthesia
(This special issue belongs to the Section Anesthesiology)
Current Trends in Urogynecology: 3rd Edition
edited by
submission deadline 28 Feb 2026 | Viewed by 326 | Submission Open
Keywords: urogynecological surgery (uterovaginal prolapse; urinary incontinence; fistulas); OAB; pharmacology; physiotherapy; LUTS
(This special issue belongs to the Section Obstetrics & Gynecology)
New Advances and Clinical Outcomes of Pediatric Endocrinology
edited by
submission deadline 28 Feb 2026 | Viewed by 319 | Submission Open
Keywords: congenital hypothyroidism; rare bone diseases; growth hormone deficiency; endocrine sequelae of cancer treatments; disorders of sex development; central diabetes insipidus; gender dysphoria
(This special issue belongs to the Section Clinical Pediatrics)
Epidemiology Associated Risks and Intervention Strategies of Childhood Obesity
edited by , and Eduardo Guzmán-Muñoz
submission deadline 28 Feb 2026 | Viewed by 280 | Submission Open
Keywords: childhood obesity; overweight; eating disorders; nutritional programs; psychological interventions; physical activity exercise; sport; physical well-being; mental well-being; quality of life
(This special issue belongs to the Section Clinical Pediatrics)
Hysterectomy Surgery—Recent Developments and Emerging Trends
edited by , and Dimitrios Zacharakis
submission deadline 28 Feb 2026 | Viewed by 187 | Submission Open
Keywords: hysterectomy; minimally invasive hysterectomy; robotic surgery; vaginal hysterectomy; surgical innovation; perioperative care
(This special issue belongs to the Section Obstetrics & Gynecology)
Current and Emerging Treatment Options in Chronic Liver Diseases
edited by Chandana B. Herath and Michael Praktiknjo
submission deadline 28 Feb 2026 | Viewed by 181 | Submission Open
Keywords: liver disease; liver fibrosis; liver cirrhosis; portal hypertension; liver cancer; therapies; immunological therapies for liver cancer; diabetic liver; type 2 diabetes and obesity; spontaneous bacterial peritonitis
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Emerging Therapies: Clinical Trials and Insights in Psoriasis
edited by and Elżbieta Krajewska-Kułak
submission deadline 28 Feb 2026 | 1 articles | Viewed by 114 | Submission Open
Keywords: psoriasis; clinical trials; biomarkers; psychodermatology; treatment; modern therapy; individualized therapy
(This special issue belongs to the Section Dermatology)
Inflammatory Bowel Disease: Clinical Pathogenesis and Management Strategies
edited by
submission deadline 28 Feb 2026 | Viewed by 69 | Submission Open
Keywords: epithelial barrier dysfunction; intestinal microbiota dysbiosis; minimally invasive surgery in IBDs; disease monitoring; perianal disease treatment; surgical complications in IBD; prehabilitation; stoma formation and management; timing of surgery in IBDs; risk stratification for IBD surgery; patient-reported outcomes post-surgery
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Recent Advances in Prevention, Management, and Rehabilitation of Head and Neck Injuries
edited by , Pier Enrico Gallenga and
submission deadline 5 Mar 2026 | 2 articles | Viewed by 2470 | Submission Open
Keywords: neck injuries; whiplash injuries; head injuries; concussion; neck pain; cervicalgia; post-concussive syndrome; post-concussive symptoms; vision disorders; hearing disorders; emergency care; emergency therapies; physical medicine and rehabilitation; musculoskeletal rehabilitation; sports medicine
(This special issue belongs to the Section Sports Medicine)
Sleep and Circadian Rhythms in Patients with Physical and Mental Disorders submission deadline 10 Mar 2026 | 5 articles | Viewed by 12260 | Submission Open
Keywords: sleep; circadian rhythms; insomnia; depression; physical health; mental health; circadian medicine; chronotype; chronotherapy; melatonin
(This special issue belongs to the Section Mental Health)
Clinical Advancements in Kidney Transplantation
edited by Louise Benning
submission deadline 10 Mar 2026 | 6 articles | Viewed by 10001 | Submission Open
Keywords: kidney transplantation; immunosuppression; immune monitoring; biomarkers; rejection; machine perfusion; graft survival
(This special issue belongs to the Section Nephrology & Urology)
New Insights in the Endovascular Treatment of Aortic Type A Dissection
edited by
submission deadline 10 Mar 2026 | 2 articles | Viewed by 4619 | Submission Open
Keywords: aortic dissection; endovascular treatment; type A dissection; thoracic aorta; stent graft; minimally invasive surgery; hybrid procedures; complications; long-term outcomes; patient selection
(This special issue belongs to the Section Cardiology)
Clinical Diagnosis and Management of Corneal Diseases
edited by , and Panagiota Ntonti
submission deadline 10 Mar 2026 | 1 articles | Viewed by 592 | Submission Open
Keywords: corneal imaging; corneal disease diagnosis; corneal therapeutics; regenerative corneal treatments; artificial intelligence in corneal diagnostics; corneal cross-linking; lamellar keratoplasty
(This special issue belongs to the Section Ophthalmology)
Bladder Cancer: Clinical Diagnosis and Treatment
edited by Răzvan Bardan and Bogdan Petrut
submission deadline 10 Mar 2026 | Viewed by 150 | Submission Open
Keywords: bladder cancer; non-muscle invasive bladder cancer (NMIBC); muscle-invasive bladder cancer (MIBC); urinary biomarkers; immunotherapy; risk stratification; surgical treatment; AI in urology; personalized medicine
(This special issue belongs to the Section Nephrology & Urology)
Clinical Advances in Minimally Invasive Gynecologic Surgery
edited by
submission deadline 10 Mar 2026 | Viewed by 87 | Submission Open
Keywords: minimally invasive gynecological surgery; MIGS; laparoscopy; robotics; natural orifice transluminal endoscopic surgery; endometriosis; endometrial cancer; vaginal hysterectomy; leiomyomas; fibroids; vNOTES
(This special issue belongs to the Section Obstetrics & Gynecology)
Current Trends and Future Challenges in Coronary Artery Disease
edited by Federica Agnello
submission deadline 10 Mar 2026 | Viewed by 80 | Submission Open
Keywords: coronary artery disease; cardiovascular prevention; coronary computed tomography angiography (CCTA); CT-derived fractional flow reserve (FFR-CT); intracoronary imaging; residual risk; functional assessment; artificial intelligence in cardiology; percutaneous coronary intervention
(This special issue belongs to the Section Cardiology)
Neurological Injury After Cardiac Arrest: Mechanisms, Prognostication, and Emerging Therapies
edited by and Nikos Gorgoraptis
submission deadline 10 Mar 2026 | Viewed by 79 | Submission Open
Keywords: cardiac arrest; hypoxic– ischaemic brain injury; neuroprognostication; neuroprotection; biomarkers; targeted tem-perature management; multimodal monitoring; neurorehabilitation
(This special issue belongs to the Section Emergency Medicine)
Latest Advances and Prospects in Valvular Heart Diseases
edited by Konstantinos M. Lampropoulos
submission deadline 10 Mar 2026 | Viewed by 65 | Submission Open
Keywords: valvular heart disease (VHD); diagnostic advances; minimally invasive surgery; transcatheter valve interventions; valve repair techniques; patient management strategies
(This special issue belongs to the Section Cardiology)
Prevention, Diagnosis, and Clinical Treatment of Corneal Diseases
edited by Rossella Anna Maria Colabelli-Gisoldi and Fabio Scarinci
submission deadline 10 Mar 2026 | Viewed by 57 | Submission Open
Keywords: dry eye disease; cornea transplant; stem cell therapy; corneal imaging; cornea disease; deep anterior lamellar keratoplasty; descemet stripping automated endothelial keratoplasty; descemet membrane endothelial keratoplasty; keratoconus; eye bank
(This special issue belongs to the Section Ophthalmology)
Rehabilitation and Management of Stroke
edited by Thomas Platz
submission deadline 15 Mar 2026 | 6 articles | Viewed by 17294 | Submission Open
Keywords: stroke; rehabilitation; evidence; implementation; neurology; neurorehabilitation
(This special issue belongs to the Section Clinical Rehabilitation)
Targeted Diagnosis and Treatment of Coronary Artery Disease: 2nd Edition
edited by
submission deadline 15 Mar 2026 | 2 articles | Viewed by 4653 | Submission Open
Keywords: coronary artery disease; myocardial revascularization; percutaneous coronary intervention; cardiac surgery; coronary artery bypass graft; intravascular ultrasound; fractional flow reserve; instantaneous wave-free ratio; angiogenesis
(This special issue belongs to the Section Cardiology)
Updates on Brain Tumors: Diagnosis and Treatment
edited by Jigisha P. Thakkar and
submission deadline 15 Mar 2026 | 1 articles | Viewed by 4531 | Submission Open
Keywords: primary brain tumors; glioblastoma; IDH mutant glioma; meningioma; brain metastases; leptomeningeal disease
(This special issue belongs to the Section Clinical Neurology)
Clinical Applications of Endoscopic Technology in Gastroenterology
edited by
submission deadline 15 Mar 2026 | 1 articles | Viewed by 1883 | Submission Open
Keywords: gastroscopy; colonoscopy; sedation; polyps; early detection; endoscopic submucosal dissection; mucosal resection; artificial intelligence in endoscopy
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Robot-Assisted Surgery: Current Trends and Future Perspectives submission deadline 15 Mar 2026 | 1 articles | Viewed by 1393 | Submission Open
Keywords: robot-assisted surgery; surgical robotics; artificial intelligence in surgery; augmented reality; surgical ergonomics; minimally invasive surgery; haptic feedback
(This special issue belongs to the Section General Surgery)
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