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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Cardiovascular Risks in Autoimmune and Inflammatory Diseases

edited by

Elena Rezus

and

Ciprian Rezus

submission deadline 20 Apr 2026 | 6 articles | Viewed by 7649 | Submission Open

Keywords: autoimmune diseases; inflammation; cardiovascular risk; atherosclerosis; biological therapy; immunomodulatory therapy; lipid metabolism; cardiovascular risk factors; thrombosis; endothelial dysfunction

(This special issue belongs to the Section Immunology & Rheumatology)

Advances in Anesthesia and Intensive Care During Perioperative Period

edited by

Philipp Simon

submission deadline 20 Apr 2026 | 3 articles | Viewed by 7164 | Submission Open

Keywords: general anesthesia; intensive care medicine; post intensive care syndrome; perioperative management; fast track; pain management; complications; postoperative outcome; digitalization; big data; AI; closed-loop systems; machine learning; clinical decision support; telemedicine

(This special issue belongs to the Section Intensive Care)

Advances in Clinical Anesthesia and Analgesia: Novel Approaches for Optimal Patient Safety and Comfort

edited by Cesare Gregoretti and Giuliano Lo Bianco

submission deadline 20 Apr 2026 | 8 articles | Viewed by 6839 | Submission Open

Keywords: pain management; pain medicine; anesthesia; analgesia; anesthesiology

(This special issue belongs to the Section Anesthesiology)

Autoimmune Skin Diseases: Innovations, Challenges, and Opportunities

edited by Shany Sherman

submission deadline 20 Apr 2026 | 4 articles | Viewed by 6104 | Submission Open

Keywords: healthcare utilization; inflammatory skin diseases; photodermatoses; collagen vascular disease; immunobullous disorders; graft-versus-host disease

(This special issue belongs to the Section Dermatology)

Immunotherapy of Hematological Malignancies: The State of the Art

edited by

Anca Colita

and

Romeo Gabriel Mihaila

submission deadline 20 Apr 2026 | 1 articles | Viewed by 4849 | Submission Open

Keywords: antibody-drug conjugates; bispecific antibodies; chimeric antigen receptor-engineered natural killer cell; chimeric antigen receptor T-cells; cytokine release syndrome; immune checkpoint in-hibitors; immunosuppression; immunotherapy; monoclonal antibodies; neurotoxicities

(This special issue belongs to the Section Hematology)

Emerging Diagnostic and Treatment Approaches for Gynecological Cancers

edited by Marco D'Indinosante

submission deadline 20 Apr 2026 | 3 articles | Viewed by 4519 | Submission Open

Keywords: gynecologic oncology; surgical gynecology; biomarkers; endometrial carcinoma; ovarian carcinoma; cervical carcinoma

(This special issue belongs to the Section Obstetrics & Gynecology)

Clinical Care and Rehabilitation for Neuromuscular Diseases

edited by

Hans-Jürgen Gdynia

submission deadline 20 Apr 2026 | 5 articles | Viewed by 4460 | Submission Open

Keywords: neuromuscular diseases; myopathy; neuropathy; motor neuron disease; amyotrophic lateral sclerosis; diseases of neuromuscular junction; neurorehabilitation; rehabilitation; clinical care; neuroscience

(This special issue belongs to the Section Clinical Rehabilitation)

Cardiogenic Shock and Cardiac Arrest: Updates, Challenges and Opportunities

edited by

Torben K. Becker

submission deadline 20 Apr 2026 | 4 articles | Viewed by 4384 | Submission Open

Keywords: cardiac arrest; extracorporeal membrane oxygenation; extracorporeal CPR; cardiopulmonary resuscitation; cardiogenic shock; resuscitation; prognostication

(This special issue belongs to the Section Cardiology)

Spine Surgery: Current Practice and Future Directions

edited by Claudio Bernucci and Francesco Costa

submission deadline 20 Apr 2026 | 2 articles | Viewed by 4228 | Submission Open

Keywords: degenerative; spinal trauma; spine tumors; neurosurgery; spine surgery; spinal deformity; scoliosis; robotics surgery; spinal cord injury; clinical practices; regenerative therapies

(This special issue belongs to the Section Clinical Neurology)

Imaging in Diagnosis and Treatment of Musculoskeletal Disorders

edited by Francesco Porta and

Florentin Ananu Vreju

submission deadline 20 Apr 2026 | 1 articles | Viewed by 3828 | Submission Open

Keywords: ultrasound; ultrasound-guided injections; imaging-guided procedures

(This special issue belongs to the Section Nuclear Medicine & Radiology)

News in the Pathogenesis, Diagnosis and Treatment of Systemic Sclerosis

edited by Mayka Freire and Bernardo Sopeña

submission deadline 20 Apr 2026 | 4 articles | Viewed by 3786 | Submission Open

Keywords: systemic sclerosis; scleroderma; capillaroscopy; autoantibodies; pathogenesis

(This special issue belongs to the Section Immunology & Rheumatology)

Clinical Management of Pediatric Heart Diseases

edited by

Michele Lioncino

submission deadline 20 Apr 2026 | 5 articles | Viewed by 3770 | Submission Open

Keywords: pediatric heart diseases; children; pediatric cardiology; congenital heart disease; clinical management; congenital heart surgery; outcome

(This special issue belongs to the Section Clinical Pediatrics)

Targeted Medicine in Postoperative Pain Management

edited by

Martina Rekatsina

and Eleni Moka

submission deadline 20 Apr 2026 | 2 articles | Viewed by 3578 | Submission Open

Keywords: precision medicine; postoperative analgesia; pain control; drug delivery systems; surgical pain management; personalized interventions

(This special issue belongs to the Section Anesthesiology)

Chronic Disease Management and Rehabilitation in Older Adults

edited by

Justyna Mazurek

submission deadline 20 Apr 2026 | 3 articles | Viewed by 3570 | Submission Open

Keywords: chronic disease; older adults; geriatric rehabilitation; holistic physiotherapy; physical activity; health outcomes; elderly people; geriatric care; health promotion

(This special issue belongs to the Section Geriatric Medicine)

Prostatectomy: Clinical Updates and Perspectives

edited by Antonio Nacchia

submission deadline 20 Apr 2026 | 2 articles | Viewed by 3048 | Submission Open

Keywords: single port; prostatectomy; robotics; RARP; prostate cancer

(This special issue belongs to the Section Nephrology & Urology)

Application of Echocardiography in the Diagnosis and Management of Cardiac Diseases

edited by

Calin Pop

and

Antoniu Petris

submission deadline 20 Apr 2026 | 3 articles | Viewed by 3006 | Submission Open

Keywords: echocardiography; cardiac diseases; 3D echo; stress; myocardial strain; intracardiac; subclinical cardiac disease

(This special issue belongs to the Section Cardiology)

Clinical Advances in Skin Cancer: A Closer Look at Non-Melanoma Types

edited by Andrea Paradisi

submission deadline 20 Apr 2026 | 3 articles | Viewed by 2938 | Submission Open

Keywords: basal cell carcinoma; squamous cell carcinoma; actinic keratosis; diagnosis; treatment; non-melanoma skin cancer (NMSC)

(This special issue belongs to the Section Dermatology)

Neuropathic Pain: From Prevention to Diagnosis and Management

edited by Enrico Martin

submission deadline 20 Apr 2026 | 1 articles | Viewed by 2869 | Submission Open

Keywords: neuropathic pain; clinical research; TMR; RPNI; preclinical studies; QoL; PROMS; translational medicine; pain mechanisms

(This special issue belongs to the Section Clinical Neurology)

Current Updates and Advances in Hemodialysis

edited by Edita Žiginskienė

submission deadline 20 Apr 2026 | 4 articles | Viewed by 2752 | Submission Open

Keywords: kidney replacement therapy; hemodialysis; hemodiafiltration; vascular access; dialysis membranes; dialysis complications; dialysis adequacy; outcomes

(This special issue belongs to the Section Nephrology & Urology)

Clinical Management of Frailty

edited by

Alejandro Alvarez-Bustos

, Walter Sepulveda-Loyola and

Isabel Rodríguez-Sánchez

submission deadline 20 Apr 2026 | 5 articles | Viewed by 2629 | Submission Open

Keywords: frailty; comprehensive geriatric assessment; assessment; monitoring; functional decline; physical performance; ex-ercise interventions; nutritional strategies; interventions; adverse outcomes

(This special issue belongs to the Section Geriatric Medicine)

Advances in the Management of Oral Lichen Planus: A Comprehensive Clinical Perspective

edited by Zuzanna Ślebioda and

Elzbieta Paszynska

submission deadline 20 Apr 2026 | 2 articles | Viewed by 2618 | Submission Open

Keywords: oral lichen planus; treatment; topical treatment; systemic treatment; oral mucosa; oral pathology; immunosuppressive therapy

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Oral Cancer: Clinical Updates and Perspectives

edited by

Jutta Ries

Mayte Buchbender

and

Ulrike Simone Speth

submission deadline 20 Apr 2026 | 1 articles | Viewed by 2344 | Submission Open

Keywords: oral cancer; oral surgery; dental implant; tooth extraction; oral health; early detection; biomarkers; targeted therapy; immunotherapy

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Implant Dentistry: New Challenges and Complication Management

edited by Jordi Gargallo

submission deadline 20 Apr 2026 | 2 articles | Viewed by 2237 | Submission Open

Keywords: navigation surgery; accuracy; computer-aided surgery; computer-assisted; three-dimensional imaging; fixed implant prostheses; zirconia; CAD/CAM; patient satisfaction; peri-implantitis; quality of life; retreatment; tooth loss; connective tissue; keratinized tissue; soft tissue management; bone regeneration; bone grafting; immediate implant placement; immediate implant loading

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Preoperative Optimization in Cardiac Surgery

edited by

Jason M. Ali

submission deadline 20 Apr 2026 | 2 articles | Viewed by 2173 | Submission Open

Keywords: preoperative optimization; cardiac surgery; risk assessment; comorbid conditions; multidisciplinary collaboration; perioperative risks; cardiovascular evaluation

(This special issue belongs to the Section Cardiology)

Respiratory Medicine in the Oldest-Old

edited by

Takae Ebihara

submission deadline 20 Apr 2026 | 2 articles | Viewed by 2092 | Submission Open

Keywords: oldest-old; respiratory system with aging; pneumonia; epidemiology; COPD; interstitial lung disease; bronchial asthma; lung cancer; mycobacterial or fungal infections; peri-/post-operative status; respiratory frailty; social problems and end of life

(This special issue belongs to the Section Respiratory Medicine)

Novel Insights into Clinical Diagnosis and Management of Degenerative Cervical Myelopathy

edited by

Carlo Brembilla

, Francesco Costa and Filippo Maria Polli

submission deadline 20 Apr 2026 | 2 articles | Viewed by 1873 | Submission Open

Keywords: degenerative cervical myelopathy (DCM); cervical spondylotic myelopathy (CSM); cervical spinal stenosis; cervical cord compression; MRI of the cervical spine; cervical spine surgery; physical therapy; rehabilitation; ossification of the posterior longitudinal ligament (OPLL); cervical deformity (e.g.; kyphosis and lordosis); patient-reported out-comes; surgical outcome prediction

(This special issue belongs to the Section Clinical Neurology)

Current Challenges and Innovations in Spine Deformity: Biomechanics, Imaging and AI-Driven Analysis

edited by Dong-Ho Kang

submission deadline 20 Apr 2026 | 2 articles | Viewed by 1630 | Submission Open

Keywords: spinal deformity; cervical deformity; biomechanics; postural alignment; sagittal imbalance; medical imaging; radiographic analysis; artificial intelligence; machine learning; deep learning; phenotyping; computer-assisted diagnosis; predictive modeling; surgical planning

(This special issue belongs to the Section Orthopedics)

Clinical Insights in Maternal–Fetal Medicine

edited by Moti Gulersen

submission deadline 20 Apr 2026 | 2 articles | Viewed by 1526 | Submission Open

Keywords: preterm birth; antenatal corticosteroids; preeclampsia; ultrasound; fetal growth; congenital anomalies; infection; maternal morbidity; diabetes; multiple gestation

(This special issue belongs to the Section Obstetrics & Gynecology)

Total Joint Arthroplasty: Clinical Advances and Innovations in Surgical Techniques and Rehabilitation

edited by

Mattia Loppini

, Marco Minelli and Federico Della Rocca

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1511 | Submission Open

Keywords: total joint arthroplasty; hip replacement; knee arthroplasty; robotic-assisted surgery; minimally invasive techniques; implant design; postoperative rehabilitation; periprosthetic joint infection; surgical innovation

(This special issue belongs to the Section Orthopedics)

Novel Technologies to Assist Emergency Medical Care

edited by

Sangsoo Han

and Young Soon Cho

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1502 | Submission Open

Keywords: emergency medical services; artificial intelligence in emergency medicine; telemedicine and remote patient monitoring; wearable health technologies; point-of-care diagnostics; automated decision support systems; robotics in emergency medicine; pre-hospital care innovations

(This special issue belongs to the Section Emergency Medicine)

New Insights into Acne Vulgaris Treatment and Management Strategies

edited by Jo Linda Maria Sinagra

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1415 | Submission Open

Keywords: acne; hormonal treatments; isotretinoin; laser therapy; antibiotic

(This special issue belongs to the Section Dermatology)

Clinical Update on Thoracic Trauma

edited by

Duilio Divisi

submission deadline 20 Apr 2026 | 3 articles | Viewed by 1341 | Submission Open

Keywords: flail chest; isolated sternal fractures; manubrio-sternal dislocation; pneumothorax; hemothorax; thoracic aortic injury; heart and pulmonary vessels lesion; intercostal artery injury; diaphragm rupture; thoracoabdominal hernia; chylothorax; esophageal perforation

(This special issue belongs to the Section Respiratory Medicine)

Acute Myeloid Leukemia: Latest Advances in Diagnostics, Therapeutic Strategies and Clinical Management: 2nd Edition

edited by Michael D. Diamantidis

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1209 | Submission Open

Keywords: ELN; ICC and WHO 2022 AML classifications; molecular AML diagnostics; AML biology; measurable residual disease (MRD); novel targeted AML therapies; AML immunotherapies; hematopoietic stem cell transplantation (HSCT)

(This special issue belongs to the Section Hematology)

Orofacial Pain: Innovations in Treatment Modalities and Patient Care

edited by

Takahiko Nagamine

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1174 | Submission Open

Keywords: orofacial pain; treatment; patient care; oral dysfunction; chronic pain; burning mouth syndrome; temporomandibular joint pain: oral cenesthopathy; atypical odontalgia; phantom bite syndrome

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Pediatric Dentistry: Real-World Clinical Insights

edited by

Ruth M. Santamaría

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1142 | Submission Open

Keywords: pediatric dentistry; minimally invasive dentistry; new technologies; biomaterials; innovative management approaches; caries management; pulp management; dental trauma; molar incisor hypomineralization; public health services research; epidemiological research; translational research

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Advances in Maternal Fetal Medicine

edited by

Georgios Eleftheriou

and Anna Franca Cavaliere

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1065 | Submission Open

Keywords: drugs use during pregnancy; fetal treatment; pregnancy complications; infectious diseases; neonatal poor adaptation syndrome

(This special issue belongs to the Section Obstetrics & Gynecology)

Recent Advances in Endocrine Surgery—2nd Edition

edited by

Gregorio Scerrino

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1012 | Submission Open

Keywords: endocrine surgery; thyroid; thyroid cancer; parathyroid; parathyroidectomy; adrenal glands; disorders of hepatobiliary and gastrointestinal tract

(This special issue belongs to the Section General Surgery)

Ischemic and Hemorrhagic Complications of Uncommon Cerebrovascular Diseases: Cutting-Edge Clinical Research, Reviews, and Expert Opinions

edited by Mariel G. Kozberg and Alexis T. Roy

submission deadline 20 Apr 2026 | 1 articles | Viewed by 984 | Submission Open

Keywords: cerebrovascular disease; ischemic stroke; hemorrhagic stroke; genetics; vasculopathy; headache; superficial siderosis; vascular malformations

(This special issue belongs to the Section Clinical Neurology)

Clinical Updates in Imaging of Musculoskeletal Diseases

edited by

Federico Zaottini

and

Riccardo Picasso

submission deadline 20 Apr 2026 | 2 articles | Viewed by 983 | Submission Open

Keywords: musculoskeletal imaging; ultrasound; magnetic resonance; sport imaging; rheumatology; nerve imaging

(This special issue belongs to the Section Nuclear Medicine & Radiology)

Optimizing Outcomes in Emergency Medicine and Cardiopulmonary Resuscitation

edited by

Andreas S. Papazoglou

and

Dimitrios V. Moysidis

submission deadline 20 Apr 2026 | 1 articles | Viewed by 939 | Submission Open

Keywords: emergency medicine; cardiopulmonary resuscitation; prehospital care; outcome prediction; post-pesuscitation care; advanced life support; emergency response systems; medical ethics; simulation in medicine

(This special issue belongs to the Section Emergency Medicine)

Carotid Artery Disease (CAD) and Its Complications: A Comprehensive Update

edited by Yacob G. Tedla

submission deadline 20 Apr 2026 | 1 articles | Viewed by 899 | Submission Open

Keywords: carotid artery disease; ischemic stroke; vascular dementia; transient ischemic attack; vascular imaging; carotid endarterectomy; carotid stent placement; risk stratification

(This special issue belongs to the Section Vascular Medicine)

Clinical Updates in Pediatric Radiology

edited by

Meriam Koob

and

Farnaz Delavari

submission deadline 20 Apr 2026 | Viewed by 804 | Submission Open

Keywords: pediatric radiology; advances in pediatric imaging; pediatric neuroimaging; artificial in-telligence in pediatric imaging; radiomics and machine learning; low-field MRI techniques; magnetic resonance imaging in pediatrics; computed tomography in pediatrics; radiation dose optimization; patient-centred imaging protocols

(This special issue belongs to the Section Clinical Pediatrics)

Clinical Advances in Minimally Invasive Spinal Treatment: 2nd Edition

edited by

Akihiko Hiyama

Haruki Funao

and

Masayuki Ishihara

submission deadline 20 Apr 2026 | 1 articles | Viewed by 704 | Submission Open

Keywords: robotic-assisted spine surgery; artificial intelligence (AI); machine learning (ML); cement-augmented pedicle screws; cement leakage risk stratification; osteoporosis pharmacotherapy; surgical navigation systems; image-guided spine surgery; predictive analytics in spine care; spine technology innovation

(This special issue belongs to the Section Orthopedics)

Intrarenal Surgery for Kidney Stones and Other Kidney Diseases

edited by Razvan Multescu

submission deadline 20 Apr 2026 | 1 articles | Viewed by 704 | Submission Open

Keywords: intrarenal surgery; flexible ureteroscopy; percutaneous nephrolithotomy (PCNL); Mini-PCNL; thulium laser; ureteral access sheaths; flexible and navigable suction (FANS); upper urinary tract urothelial tumors

(This special issue belongs to the Section Nephrology & Urology)

Cardiac MRI: Current Techniques and Future Directions

edited by

Édouard Gerbaud

submission deadline 20 Apr 2026 | 1 articles | Viewed by 688 | Submission Open

Keywords: cardiac magnetic resonance imaging; technology; sequences; applications; acute coronary syndrome; intravascular imaging; CT-scanner

(This special issue belongs to the Section Cardiology)

New Advances and Clinical Outcomes of Endocrinology

edited by Stefana Catalina Bilha and

Cristina Preda

submission deadline 20 Apr 2026 | 1 articles | Viewed by 605 | Submission Open

Keywords: endocrinology; obesity; metabolic and bone disease; chronic conditions

(This special issue belongs to the Section Endocrinology & Metabolism)

Innate Immunity in Overdrive: Novel Insights into Autoinflammatory Syndromes

edited by Alessandro Conforti

submission deadline 20 Apr 2026 | 1 articles | Viewed by 491 | Submission Open

Keywords: autoinflammatory diseases; innate immunity; inflammasome; cytokines; Interleukin-1; monogenic syndromes; polygenic autoinflammatory disorders; adult-onset Still’ s disease; Behç et’ s disease; targeted therapy; disease registries; real-world evidence; VEXAS syndrome; UBA1 mutations; precision medicine; biomarkers; outcome assessment

(This special issue belongs to the Section Immunology & Rheumatology)

Peritoneal Dialysis and Hemodialysis: Early and Late Outcomes

edited by

Keren Cohen-Hagai

and

David Pereg

submission deadline 20 Apr 2026 | 1 articles | Viewed by 479 | Submission Open

Keywords: peritoneal dialysis; dialysis; hemodialysis; chronic kidney disease; end-stage renal disease

(This special issue belongs to the Section Nephrology & Urology)

Skin Cancer: Prevention, Diagnosis, Quality of Life and Treatment Outcomes

edited by Athanassios A. Kyrgidis and

Aimilios Lallas

submission deadline 20 Apr 2026 | 1 articles | Viewed by 419 | Submission Open

Keywords: skin cancer; melanoma; squamous cell carcinoma; basal cell carcinoma; clinical biomarkers; dermoscopy; quality of life

(This special issue belongs to the Section Dermatology)

New Advances in Orthopedic Knee Joint Preserving and Reconstructive Surgery

edited by

Dong Jin Ryu

and

Sung-Sahn Lee

submission deadline 20 Apr 2026 | 1 articles | Viewed by 404 | Submission Open

Keywords: cartilage regeneration; patient-specific instrumentation; knee robotic surgery; patient-specific surgical device; future orthopedics

(This special issue belongs to the Section Orthopedics)

Displaying special issue 751-800 on page 16 of 31.

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