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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Cardiac Arrest: Strategies, Innovations, and Improvements in Outcomes
edited by
submission deadline 15 Jun 2026 | Viewed by 991 | Submission Open
Keywords: cardiac arrest; cardiopulmonary resuscitation; post-cardiac arrest syndrome; neurological outcomes
(This special issue belongs to the Section Cardiology)
New Clinical Advances in Pediatric Asthma
edited by
submission deadline 15 Jun 2026 | 1 articles | Viewed by 949 | Submission Open
Keywords: pediatric asthma; clinical management; treatment advances; diagnostic advances; biologic therapy; inhaled steroids; control of asthma; exacerbation prevention; quality of life
(This special issue belongs to the Section Clinical Pediatrics)
Transjugular Intrahepatic Portosystemic Shunt: Challenges and Perspectives—2nd Edition
edited by , Stefania Gioia and
submission deadline 15 Jun 2026 | 1 articles | Viewed by 691 | Submission Open
Keywords: hepatic encephalopathy; spontaneous portal-systemic shunts; transjugular intrahepatic portosystemic shunt; cirrhosis; portal hypertension; sarcopenia; myosteatosis; gastrointestinal bleeding; ascites; non cirrhotic portal hypertension
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Dental Implantology: Clinical Updates and Perspectives—2nd Edition
edited by
submission deadline 15 Jun 2026 | 1 articles | Viewed by 672 | Submission Open
Keywords: dental implantology; reconstructive surgery; biomaterials; tissue engineering; regenerative medicine; digital dentis-try; periimplantitis; peri-implant soft tissues
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Congenital Heart Diseases: Epidemiology, Treatment and Lifelong Support
edited by Sebastian Freilinger, , and Oliver Dewald
submission deadline 15 Jun 2026 | 1 articles | Viewed by 610 | Submission Open
Keywords: congenital heart disease (CHD); adults with CHD; epidemiology; comorbidities; intervention; surgical treatment; psychological aspects; quality of life (QoL); risk factors; rehabilitation; health promotion; prevention; health literacy; physical activity; lifelong support
(This special issue belongs to the Section Cardiology)
Interventional Cardiology: Recent Developments and Future Challenges
edited by and George Kassimis
submission deadline 15 Jun 2026 | Viewed by 324 | Submission Open
Keywords: percutaneous coronary intervention (PCI); drug-eluting stents (DES); high risk percutaneous coronary intervention (CHIP); chronic total occlusions (CTO); intravascular imaging (IVUS; OCT); coronary physiology (FFR; iFR); antiplatelet therapy; complex coronary interventions; mechanical circulatory support (MCS)
(This special issue belongs to the Section Cardiology)
Clinical Advances in Cancer Imaging submission deadline 15 Jun 2026 | Viewed by 247 | Submission Open
Keywords: pelvic oncology; cancer imaging; CT; MRI; tumor staging; treatment response; morphological criteria; gynecologic cancer; bladder cancer; rectal cancer; artificial intelligence; radiomics; texture analysis; image biomarkers; clinical imaging
(This special issue belongs to the Section Oncology)
New Advances of Infectious Disease Epidemiology submission deadline 15 Jun 2026 | Viewed by 121 | Submission Open
Keywords: infectious disease epidemiology; genomic sequencing; computational modeling; collaborative surveillance; digital epidemiology; one health; pandemic intelligence; public health data integration; emerging pathogens; epidemiologic insights
(This special issue belongs to the Section Epidemiology & Public Health)
Traumatic Brain Injury: Clinical Diagnosis and Management
edited by Alessio Caccioppola
submission deadline 15 Jun 2026 | Viewed by 107 | Submission Open
Keywords: glasgow coma scale; intracranial pressure monitoring; traumatic brain injury; diffuse axonal injury; post-traumatic epilepsy; decompressive craniectomy; neuromonitoring
(This special issue belongs to the Section Brain Injury)
Clinical Advancements in Foot and Ankle Surgery: 2nd Edition
edited by
submission deadline 15 Jun 2026 | Viewed by 100 | Submission Open
Keywords: flat foot; hindfoot motion; diabetic foot; hallux valgus; foot infection; foot trauma
(This special issue belongs to the Section Orthopedics)
Current Challenges and Opportunities in Assisted Reproductive Technologies
edited by Andrea Milostić-Srb and
submission deadline 15 Jun 2026 | Viewed by 95 | Submission Open
Keywords: artificial reproductive technologies; ART; mental health effect on ART; IVF; AI in reproductive medicine
(This special issue belongs to the Section Obstetrics & Gynecology)
Aortic Surgery: State of the Art and Future Directions submission deadline 15 Jun 2026 | Viewed by 76 | Submission Open
Keywords: aortic surgery; aortic aneurysm; aortic dissection; aortic arch; biomaterials; endovascular approach; FET; TEVAR
(This special issue belongs to the Section Cardiovascular Medicine)
Novel Diagnostic and Therapeutic Perspectives in Systemic Sclerosis
edited by Mislav Radić
submission deadline 15 Jun 2026 | Viewed by 59 | Submission Open
Keywords: systemic sclerosis; biomarkers; diagnosis; treatment; diagnostic imaging technique; early detection
(This special issue belongs to the Section Immunology & Rheumatology)
Clinical Diagnosis and Management of Erectile Dysfunction
edited by Maurizio De Rocco Ponce and
submission deadline 15 Jun 2026 | Viewed by 57 | Submission Open
Keywords: erectile dysfunction; clinical management; cardiovascular disease; penile prosthesis; personalized medicine; hipogonadism
(This special issue belongs to the Section Reproductive Medicine & Andrology)
New Advances in Stereotactic Radiosurgery
edited by Shafak S. Aluwini
submission deadline 18 Jun 2026 | 2 articles | Viewed by 1429 | Submission Open
Keywords: stereotactic radiosurgery; clinical outcomes; brachytherapy; IMRT; brain metastases; arteriovenous malformations; functional disorders; radiosurgery
(This special issue belongs to the Section Oncology)
Gynecologic Oncology: Current Therapies and New Frontiers
edited by Laura Paleari and Mariangela Rutigliani
submission deadline 19 Jun 2026 | Viewed by 95 | Submission Open
Keywords: ovarian cancers; gynecological cancer; drug delivery; AI; screening; new therapies
(This special issue belongs to the Section Obstetrics & Gynecology)
Gynecologic and Obstetric Pathologies: From Birth to Menopause (Third Edition) submission deadline 20 Jun 2026 | 6 articles | Viewed by 21599 | Submission Open
Keywords: obstetrics; gynecology; pathology; pediatric and adolescent gynecology; menopause; urinary disorders; infertility; gynecologic oncology; maternal– fetal medicine; incontinence; menstruation; reproduction; polycystic ovarian syndrome; endometriosis; dysmenorrhea; assisted reproduction; IVF; laparoscopy; hysteroscopy; gynecologic robotic surgery; high-risk pregnancy
(This special issue belongs to the Section Obstetrics & Gynecology)
Advances in Trauma Care and Emergency Medicine submission deadline 20 Jun 2026 | 3 articles | Viewed by 13690 | Submission Open
Keywords: trauma; trauma care; emergency medicine; pre-hospital; emergency room; intensive care unit
(This special issue belongs to the Section Emergency Medicine)
Clinical Advances in Metabolic Dysfunction-Associated Steatotic Liver Disease
edited by Hirsh D. Trivedi
submission deadline 20 Jun 2026 | 5 articles | Viewed by 10347 | Submission Open
Keywords: metabolic dysfunction-associated steatotic liver disease; MASLD; non-alcoholic fatty liver disease; NAFLD; liver disease; liver fibrosis; metabolic syndrome
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Latest Advances in Orthodontics
edited by
submission deadline 20 Jun 2026 | 3 articles | Viewed by 7146 | Submission Open
Keywords: digital treatment planning; clear aligners; skeletal anchorage; OSAS; artificial intelligence
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Advancements in Gait Rehabilitation: Innovative Approaches and Clinical Insights submission deadline 20 Jun 2026 | 4 articles | Viewed by 6082 | Submission Open
Keywords: sarcopenia; swallowing therapy; physical therapy; early mobilization; early rehabilitation; robot-assisted gait training; neurorehabilitation; wearable sensors
(This special issue belongs to the Section Clinical Rehabilitation)
Evidence-Based Diagnosis and Clinical Management of Low Back Pain submission deadline 20 Jun 2026 | 3 articles | Viewed by 5525 | Submission Open
Keywords: low back pain; classification systems; risk stratification; health services research; management strategies; timing and sequencing; prognosis; predictor; clinical decision making; primary care
(This special issue belongs to the Section Clinical Rehabilitation)
AI in Maternal Fetal Medicine and Perinatal Management
edited by Ariel Many
submission deadline 20 Jun 2026 | 2 articles | Viewed by 5515 | Submission Open
Keywords: maternal fetal medicine; high-risk pregnancy; perinatal management; artificial intelligence (AI) in obstetrics; fetal growth abnormalities; preterm labor prediction
(This special issue belongs to the Section Obstetrics & Gynecology)
Clinical Advances in Trauma and Orthopaedic Surgery
edited by Valerio Pace and Pierluigi Antinolfi
submission deadline 20 Jun 2026 | 3 articles | Viewed by 5512 | Submission Open
Keywords: orthopaedic surgery; hand/wrist surgery; tendon injury; ligament injury; artificial intelligence (AI); robotic surgery; orthopaedic injections; nerve injury
(This special issue belongs to the Section Orthopedics)
Maternal–Fetal Medicine: Current Status, Challenges, and Future Directions
edited by Jessian Munoz
submission deadline 20 Jun 2026 | 5 articles | Viewed by 4641 | Submission Open
Keywords: maternal– fetal medicine; preterm delivery; preterm birth management; newborn; obstetrics; high-risk pregnancy; perinatal outcome; placenta accreta; fetal surgery
(This special issue belongs to the Section Obstetrics & Gynecology)
Advancements in Femtosecond Laser Applications
edited by Luca Schwarzenbacher, Eva Stifter and Philipp Roberts
submission deadline 20 Jun 2026 | 4 articles | Viewed by 4411 | Submission Open
Keywords: femtosecond laser; cataract surgery; DSAEK; DALK; femto-CAIRS; congenital cataract
(This special issue belongs to the Section Ophthalmology)
Advances in Clinical Approaches to Breast Cancer Diagnosis and Treatment
edited by
submission deadline 20 Jun 2026 | 2 articles | Viewed by 4229 | Submission Open
Keywords: breast cancer; diagnosis; precision medicine; molecular profiling; targeted therapy; breast-conserving surgery; minimally invasive techniques; artificial intelligence; personalized medicine; radiation therapy
(This special issue belongs to the Section Oncology)
Antithrombotic Therapies for Acute Coronary Syndrome and Atrial Fibrillation submission deadline 20 Jun 2026 | 2 articles | Viewed by 3480 | Submission Open
Keywords: atrial fibrillation; acute coronary syndrome; antiplatelet agents; anticoagulants; thrombolysis; direct coagulation factor inhibitors; medical laboratory technology
(This special issue belongs to the Section Cardiology)
Ultrasound-Guided Biopsy of Gynecologic Tumors: Technique and Clinical Application
edited by and Alexandros Daponte
submission deadline 20 Jun 2026 | 1 articles | Viewed by 3472 | Submission Open
Keywords: ultrasound-guided biopsy; gynecologic tumors; ovarian cancer; biopsy technique; precision diagnosis; endometrial lesions
(This special issue belongs to the Section Obstetrics & Gynecology)
Updates on the Clinical Applications of Dental Restorative Materials
edited by
submission deadline 20 Jun 2026 | 1 articles | Viewed by 3377 | Submission Open
Keywords: restorative dentistry; restorations; adhesive dentistry; resin composites; ceramics; aesthetics; dental materials; direct restorations; indirect restorations; conservative dentistry; prosthetic dentistry; partial restorations; total restorations
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Innovations in the Clinical Management of Retinal Diseases: Emerging Therapies and Visual Rehabilitation submission deadline 20 Jun 2026 | 3 articles | Viewed by 3021 | Submission Open
Keywords: retinal diseases; macular degeneration; maculopathies; diabetic retinopathy; retinal vascular occlusions; retinitis pigmentosa
(This special issue belongs to the Section Ophthalmology)
Genitourinary Cancers: Clinical Advances and Practice Updates
edited by David Benjamin and Arash Rezazadeh Kalebasty
submission deadline 20 Jun 2026 | 3 articles | Viewed by 2920 | Submission Open
Keywords: rare tumors; genitourinary cancers; urachal cancer; penile cancer; testicular cancer; variant histology
(This special issue belongs to the Section Nephrology & Urology)
Advances in Diagnosis and Treatment of Urological Cancers
edited by Davide Campobasso, and
submission deadline 20 Jun 2026 | 2 articles | Viewed by 2702 | Submission Open
Keywords: prostate cancer; kidney cancer; urothelial carcinoma; testis cancer; mini-invasive surgery; precision surgery; target therapy; immunotherapy; nuclear medicine; artificial intelligence; augmented reality; biomarkers; prognostic factors and models; focal therapy; radiotherapy; imaging; genetics
(This special issue belongs to the Section Nephrology & Urology)
State-of-the-Art in Cardiac Surgery: Progress, Challenges and Opportunities
edited by Tomasz Plonek and Sleiman Sebastian Aboul-Hassan
submission deadline 20 Jun 2026 | 3 articles | Viewed by 2502 | Submission Open
Keywords: aorta ascendens; minimally invasive surgery; aortic arch surgery; off pump coronary surgery; arterial grafts
(This special issue belongs to the Section Cardiology)
Novel Aspects of Endocrine Care: From Patient-Centred Management of Endocrine Diseases to Guidelines Standards submission deadline 20 Jun 2026 | 2 articles | Viewed by 2449 | Submission Open
Keywords: endocrine tumour; hormone; biomarker; neuroendocrine tumour; thyroidectomy; parathyroidectomy; bone; ad-renal gland; osteoporosis; pituitary gland; autoimmune; antibody; clinical study; computed tomography
(This special issue belongs to the Section Endocrinology & Metabolism)
New Insights in Maxillofacial Surgery
edited by
submission deadline 20 Jun 2026 | 1 articles | Viewed by 2222 | Submission Open
Keywords: maxillofacial surgery; surgical techniques; imaging technologies; biomaterials; regenerative medicine
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Recent Advances in Transcatheter Aortic Valve Replacement: Second Edition
edited by and Maciej Dąbrowski
submission deadline 20 Jun 2026 | 3 articles | Viewed by 2078 | Submission Open
Keywords: aortic stenosis; transcatheter; bioprosthesis; TAVI; transcatheter aortic valve replacement
(This special issue belongs to the Section Cardiovascular Medicine)
Autoimmune Diseases and Multisystem Inflammation: Pathophysiology and Therapeutic Strategies
edited by
submission deadline 20 Jun 2026 | 1 articles | Viewed by 1631 | Submission Open
Keywords: autoimmune diseases; cardiovascular diseases; cutaneous diseases; gastrointestinal diseases; pulmonary diseases; renal diseases; systemic manifestation; rheumatoid arthritis; systemic lupus erythematosus; vasculitis
(This special issue belongs to the Section Immunology & Rheumatology)
Current Challenges and Perspectives in Liver Transplantation
edited by Bogdan Dorobanţu, and Waldo Concepcion
submission deadline 20 Jun 2026 | 1 articles | Viewed by 1475 | Submission Open
Keywords: liver transplantation; liver surgery; liver cirrhosis; liver disease; alcoholic and non-alcoholic steatohepatitis; cholangiocarcinoma; hepatocellular carcinoma; auxiliary liver transplantation
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Innovations in Psychosis and Schizophrenia: New Findings and Implications
edited by
submission deadline 20 Jun 2026 | 2 articles | Viewed by 1403 | Submission Open
Keywords: schizophrenia; psychosis; psychopathology; neurobiology; assessment; pharmacological treatment; psychosocial interventions
(This special issue belongs to the Section Mental Health)
Current Perspectives and Innovations in Urogynecology
edited by Stavros Athanasiou
submission deadline 20 Jun 2026 | 2 articles | Viewed by 1320 | Submission Open
Keywords: urogynecology; pelvic organ prolapse; urinary incontinence; overactive bladder; pelvic floor surgery; reconstructive surgery; minimally invasive surgery; pelvic floor disorders; innovative surgical techniques; quality of life
(This special issue belongs to the Section Obstetrics & Gynecology)
Therapies for Heart Failure: Clinical Updates and Perspectives
edited by Cristina Tudoran, Stela Iurciuc and Dragos Cozma
submission deadline 20 Jun 2026 | 2 articles | Viewed by 1317 | Submission Open
Keywords: mechanisms of heart failure; new therapies for heart failure; chronic and acute heart failure; new approaches to managing heart failure patients; special populations; clinical outcome
(This special issue belongs to the Section Cardiology)
New Perspectives in Maternal–Fetal Medicine
edited by Catalina de Paco-Matallana
submission deadline 20 Jun 2026 | 1 articles | Viewed by 1219 | Submission Open
Keywords: maternal– fetal medicine; prenatal diagnostics; fetal therapy; precision medicine; neonatal outcomes; maternal health
(This special issue belongs to the Section Obstetrics & Gynecology)
Clinical Advances in the Pharmacotherapy of Diabetes
edited by Jonathan Watanabe, and
submission deadline 20 Jun 2026 | 1 articles | Viewed by 1003 | Submission Open
Keywords: diabetes; microvascular complications; macrovascular complications; diabetes technology; pharmacoepidemiology; care delivery; novel therapies
(This special issue belongs to the Section Pharmacology)
Cardiovascular Imaging: Diagnosis and Therapeutic Guidance in Clinical Practice
edited by
submission deadline 20 Jun 2026 | 1 articles | Viewed by 995 | Submission Open
Keywords: cardiovascular magnetic resonance; cardiac imaging; T1 and T2 mapping; myocardial tissue characterization; late gadolinium enhancement; ischemic heart disease; cardiomyopathies; valvular heart disease; therapeutic guidance; precision medicine; mitral valve prolapse
(This special issue belongs to the Section Cardiology)
New Clinical Advances in Breast Reconstruction
edited by
submission deadline 20 Jun 2026 | 2 articles | Viewed by 872 | Submission Open
Keywords: breast reconstruction; autologous (flap) reconstruction; implant-based reconstruction; microsurgery and perforator flaps; robotic surgery/endoscopic surgery; fat grafting (lipofilling); patient-reported outcomes; reconstructive surgical innovation
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
Parkinson's Disease: Recent Advances in Diagnosis and Treatment submission deadline 20 Jun 2026 | 1 articles | Viewed by 801 | Submission Open
Keywords: Parkinson’ s disease; disease-modifying therapies; artificial intelligence; microbiome; alpha-synuclein; neuroimaging
(This special issue belongs to the Section Clinical Neurology)
Stroke in Patients with Atrial Fibrillation: Risk, Manifestation and Prevention submission deadline 20 Jun 2026 | 1 articles | Viewed by 642 | Submission Open
Keywords: anticoagulant treatment; atrial fibrillation; arrhythmia; personalized medicine; stroke
(This special issue belongs to the Section Cardiology)
The New Era of Urological Surgery: Technology-Enhanced Clinical Outcomes submission deadline 20 Jun 2026 | Viewed by 587 | Submission Open
Keywords: urology; surgery; robotic surgery; artificial intelligence; urological cancer
(This special issue belongs to the Section Nephrology & Urology)
Advances in Cardiovascular Rehabilitation: The Central Role of Exercise in Prevention and Care
edited by Massimo Pistono
submission deadline 20 Jun 2026 | 2 articles | Viewed by 546 | Submission Open
Keywords: cardiac rehabilitation; secondary prevention; physical exercise; cardiovascular health; aerobic exercise; cardio-oncology rehabilitation
(This special issue belongs to the Section Cardiovascular Medicine)
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