Interventional Cardiology: Recent Developments and Future Challenges

Dear Colleagues,

Since the first balloon angioplasty by Andreas Grüntzig in 1977, interventional cardiology has undergone remarkable evolution, becoming a cornerstone in the management of coronary artery disease. Over the decades, advancements such as bare-metal (BMS) and drug-eluting stents (DES), intravascular imaging, and physiology-guided interventions have dramatically improved procedural outcomes and patient prognosis.

This Special Issue focuses on contemporary advances and future directions in percutaneous coronary intervention (PCI) and related non-structural interventional procedures. Topics of interest include the evolution of DES platforms, drug-coated balloons (DCBs), and novel atherectomy devices for calcified and fibrotic lesions. Emerging techniques such as physiology-guided PCI (FFR, iFR), intravascular imaging (IVUS, OCT), and hybrid revascularization strategies are redefining precision treatment. Special attention will be given to high-risk PCI, including left main interventions, bifurcation stenting, and chronic total occlusion (CTO) management. Additionally, the role of pharmacological advancements in antiplatelet and anticoagulation therapy, as well as bleeding avoidance strategies, will be explored.

We invite the submission of original research articles, systematic reviews, meta-analyses, clinical studies, technical innovations, and expert perspectives. Submissions should contribute to advancing the science, technology, and clinical practice of interventional cardiology, fostering ongoing innovation in a rapidly evolving field.

Dr. Andreas Mitsis
Dr. George Kassimis
Guest Editors

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