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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advanced Diagnostic and Therapeutic Strategies for Sarcoidosis submission deadline 20 Jan 2026 | 2 articles | Viewed by 2742 | Submission Open
Keywords: sarcoidosis; cardiac sarcoidosis; pulmonary fibrosis; magnetic resonance imaging; FDG-PET/CT; echocardiography; neurosarcoidosis; differential diagnosis; hypercalcaemia; IGRA; sarcoidosis-associated pulmonary hypertension; fatigue; corticosteroids; metotrexat; infliximab; antifibrotic treatment; lung transplantation; artificial intelligence; broncho-alveolar lavage; cytokines
(This special issue belongs to the Section Respiratory Medicine)
Advances in Tuberculosis: Comprehensive Insights and Management Strategies
edited by Aliaksandr Skrahin
submission deadline 20 Jan 2026 | 2 articles | Viewed by 2556 | Submission Open
Keywords: pulmonary and extra-pulmonary tuberculosis (TB); TB epidemiology; TB screening; TB prevention; TB diagnostics; TB treatment; TB co-infections (e.g.; HIV; Hepatitis B and C); TB co-morbidities (e.g.; diabetes); host and Mycobacteria genetic; molecular mechanisms and genotype/phenotype correlations
(This special issue belongs to the Section Infectious Diseases)
Insights and Innovations in Sports Cardiology submission deadline 20 Jan 2026 | 3 articles | Viewed by 2476 | Submission Open
Keywords: sports cardiology; athlete heart; cardiovascular screening; arrhythmias; sudden cardiac death; cardiac rehabilitation; exercise prescription; mobile health; preventive cardiology; personalized medicine; pediatric fitness
(This special issue belongs to the Section Sports Medicine)
Glaucoma Surgery: Current Challenges and Future Perspectives submission deadline 20 Jan 2026 | 3 articles | Viewed by 1994 | Submission Open
Keywords: glaucoma; filtration surgery; trabeculectomy; MIGS; scarring; anti-metabolites; wound healing; anti-fibrotics
(This special issue belongs to the Section Ophthalmology)
Endometriosis: Diagnosis and Treatment submission deadline 20 Jan 2026 | 2 articles | Viewed by 1921 | Submission Open
Keywords: endometriosis; diagnosis; video laparoscopy with and without robotic assistance; chronic pelvic pain; fertility preservation; minimally invasive surgery; biomarkers; artificial intelligence in endometriosis; adenomyosis; and adenomyoma care; multidisciplinary care; personalized medicine
(This special issue belongs to the Section Obstetrics & Gynecology)
Acute Myocardial Infarction: Diagnosis, Treatment, and Rehabilitation
edited by
submission deadline 20 Jan 2026 | 1 articles | Viewed by 1810 | Submission Open
Keywords: acute myocardial infarction; coronary angioplasty; acute heart failure; cardiogenic shock; rehabilitation programs
(This special issue belongs to the Section Cardiovascular Medicine)
Neuro-Cardiology: An Obligation for Combined Care of Stress and Heart Diseases
edited by Mario J. Garcia and
submission deadline 20 Jan 2026 | 1 articles | Viewed by 1217 | Submission Open
Keywords: neuro-cardiology; cardiovascular; segmental remodeling; stressors; hypertension; triple S
(This special issue belongs to the Section Cardiology)
Advancements in the Treatment of Myeloproliferative Neoplasms and Myelodysplastic Syndromes
edited by Ivan Krečak, Marko Skelin and Zinaida Perić
submission deadline 20 Jan 2026 | 2 articles | Viewed by 1094 | Submission Open
Keywords: myeloproliferative neoplasms; myelodysplastic syndromes; treatment; risk stratification; prognosis
(This special issue belongs to the Section Hematology)
Cardiac Arrest Research: Neuroprognostication and Improving Outcomes
edited by and Jin-hong Min
submission deadline 20 Jan 2026 | 1 articles | Viewed by 1054 | Submission Open
Keywords: cardiac arrest; prognosis; hypothermia; induced; resuscitation; magnetic resonance imaging; electroencephalography; blood pressure; hypoxia-ischemia; brain; extracorporeal membrane oxygenation
(This special issue belongs to the Section Cardiovascular Medicine)
Idiopathic Pulmonary Fibrosis (IPF): Current Perspectives and Future Directions
edited by Vito D’Agnano
submission deadline 20 Jan 2026 | 1 articles | Viewed by 999 | Submission Open
Keywords: pulmonary fibrosis; IPF; ILD; antifibrotics; EMT; respiratory physiology; metabolism
(This special issue belongs to the Section Respiratory Medicine)
New Perspectives in Chronic Kidney Disease, Transplantation and Immune System
edited by and Dimitrios A. Tsakiris
submission deadline 20 Jan 2026 | 1 articles | Viewed by 918 | Submission Open
Keywords: kidney transplantation; HLA; matching at the epitope level; DSAs; complement; kidney disease epigenetics; diabetic nephropathy; hemostasis; graft rejection; B and T cell immunophenotyping; end stage renal disease
(This special issue belongs to the Section Nephrology & Urology)
Cardiac and Pulmonary Involvements in High-Risk Neonatal Cohorts: Short- and Long-Term Issues
edited by Arvind Sehgal
submission deadline 20 Jan 2026 | 1 articles | Viewed by 916 | Submission Open
Keywords: fetal growth restriction; lung disease; cardiac maladaptation; placenta; public health; neurodevelopment; long term; adulthood; Barker’ s hypothesis; newborn; vascular
(This special issue belongs to the Section Clinical Pediatrics)
Artificial Intelligence (AI) in Dental Clinical Practice
edited by and Keiichiro Watanabe
submission deadline 20 Jan 2026 | 1 articles | Viewed by 900 | Submission Open
Keywords: artificial intelligence; dental diagnostics; machine learning; deep learning; digital dentistry; clinical decision support; diagnostic automation; data transparency; evidence-based dentistry
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Current Practice and Future Perspectives on Laryngeal Surgery submission deadline 20 Jan 2026 | 1 articles | Viewed by 866 | Submission Open
Keywords: laryngeal disorders; laryngeal surgery; microsurgery; endoscopic surgery; open surgery; laser surgery
(This special issue belongs to the Section Otolaryngology)
Aortic Valve Disease: Current Evolution and Future Opportunities
edited by Gianluigi Perri
submission deadline 20 Jan 2026 | 1 articles | Viewed by 796 | Submission Open
Keywords: aortic valve disease; aortic valve repair; Ross procedure; aortic valve replacement; diagnosis of aortic valve disease
(This special issue belongs to the Section Cardiology)
Rehabilitation and Treatment of Post-COVID-19 Condition submission deadline 20 Jan 2026 | 1 articles | Viewed by 787 | Submission Open
Keywords: post-COVID-19 condition; myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS); comorbidities; interdisciplinary; multimodal; digital medicine; rehabilitation; treatment; health-related quality of life; disability; return to work
(This special issue belongs to the Section Clinical Rehabilitation)
Multiple Myeloma: Therapeutic and Management Strategies
edited by Terri Parker
submission deadline 20 Jan 2026 | 1 articles | Viewed by 769 | Submission Open
Keywords: multiple myeloma; frontline treatment; monoclonal antibodies; sequencing of treatment; immunotherapy; CAR T; Bi-specific T cell engagers; toxicity management
(This special issue belongs to the Section Hematology)
Obesity-Related Metabolic and Cardiovascular Disorders
edited by and Federica Vinciguerra
submission deadline 20 Jan 2026 | 1 articles | Viewed by 698 | Submission Open
Keywords: obesity; type 2 diabetes mellitus; insulin resistance; metabolic syndrome; cardiovascular disease; lipid disorder; adipose tissue dysfunction; visceral adiposity; cardiometabolic risk; endothelial dysfunction; health disparities; gut microbiota; bariatric surgery; precision medicine
(This special issue belongs to the Section Cardiovascular Medicine)
Clinical Advances in Prenatal Diagnosis and Fetal Therapy
edited by
submission deadline 20 Jan 2026 | 1 articles | Viewed by 676 | Submission Open
Keywords: prenatal diagnosis; fetal therapy; genetic screening; non-invasive testing; fetal surgery; imaging technologies; high-risk pregnancies; in utero treatments; stem cell therapies; clinical innovations
(This special issue belongs to the Section Obstetrics & Gynecology)
Shaping Modern Gastroenterology: Bridging Advancements in Digestive Endoscopy and Clinical Research
edited by Manuele Furnari and Stefano Kayali
submission deadline 20 Jan 2026 | 1 articles | Viewed by 582 | Submission Open
Keywords: digestive endoscopy; gastrointestinal disorders; endoscopic ultrasound (EUS); endoscopic retrograde cholangiopancreatography (ERCP); therapeutic endoscopy; artificial intelligence; pancreatic and biliary diseases; small bowel pathology; early neoplastic lesions; inflammatory bowel diseases (IBDs); translational gastroenterology; endoscopic submucosal dissection (ESD); per-oral endoscopic myotomy (POEM); endoscopic imaging; gastrointestinal pathophysiology
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Cardiopulmonary Resuscitation in the Emergency Care Unit
edited by , Felipe Fernández-Méndez, and
submission deadline 20 Jan 2026 | 1 articles | Viewed by 549 | Submission Open
Keywords: cardiopulmonary resuscitation; advanced life support; new technologies; special circumstances; emergency care unit
(This special issue belongs to the Section Emergency Medicine)
Current Status and Future of Urological Surgery
edited by , Davide De Marchi and
submission deadline 20 Jan 2026 | 1 articles | Viewed by 499 | Submission Open
Keywords: urological surgery; robotic-assisted surgery; minimally invasive surgery; artificial intelligence; augmented reality; surgical navigation; endourology; laparoscopic urology; reconstructive urology; functional urology; bph treatment; urinary incontinence; prostate cancer surgery; bladder cancer surgery; surgical innovation; digital surgery
(This special issue belongs to the Section Nephrology & Urology)
Clinical Comparisons of Nonpharmaceutical and Pharmaceutical Analgesia
edited by and
submission deadline 20 Jan 2026 | Viewed by 389 | Submission Open
Keywords: acute pain; chronic pain; postoperative pain; non-pharmaceutical; pharmaceutical; analgesia; clinical
(This special issue belongs to the Section Anesthesiology)
Recent Advances and Future Perspectives of Subarachnoid Hemorrhage
edited by Alexandros Doukas and Athanasios K. Petridis
submission deadline 20 Jan 2026 | 1 articles | Viewed by 364 | Submission Open
Keywords: subarachnoid hemorrhage; neuromonitoring; neurocritical care; neurointerventions; neurointensive care
(This special issue belongs to the Section Clinical Neurology)
Beyond the Kidney: Managing Chronic Kidney Disease in the Era of Cardio-Metabolic-Kidney Syndrome submission deadline 20 Jan 2026 | Viewed by 347 | Submission Open
Keywords: chronic kidney disease; disease-modifying therapy; physical exercise; cardio-metabolic-kidney syndrome; SGLT2 in-hibitors; MRA; renal nutrition; innovative therapies; low protein diet
(This special issue belongs to the Section Nephrology & Urology)
Clinical Updates and Current Challenges in Obstetrical Anesthesia
edited by Michael Froelich
submission deadline 20 Jan 2026 | Viewed by 323 | Submission Open
Keywords: obstetrical anesthesia; clinical innovation; practice guidelines; neuraxial techniques; enhanced recovery; risk stratification; maternal safety; multimodal analgesia; health systems innovation; global and low-resource care
(This special issue belongs to the Section Obstetrics & Gynecology)
Metabolic Dysregulation Across the Spectrum from Anorexia Nervosa to Obesity
edited by Andriana C. Kaliora
submission deadline 20 Jan 2026 | Viewed by 278 | Submission Open
Keywords: metabolic dysregulation; anorexia nervosa; obesity; environmental factors in metabolic health; gut microbiota and metabolism; hormonal regulation of appetite; inflammation and metabolic disorders; dietary influence on metabolism
(This special issue belongs to the Section Endocrinology & Metabolism)
Cardiometabolic Insights into Metabolic Dysfunction: From Mechanisms to Therapeutic Strategies
edited by Alessandro Andreis, and
submission deadline 20 Jan 2026 | 1 articles | Viewed by 269 | Submission Open
Keywords: cardiovascular complications; pharmacological; interventional strategies; cardiology; endocrinology; hepatology
(This special issue belongs to the Section Cardiology)
Innovations and Evolution of Extracorporeal Organ Support in Critical Care
edited by , and Antonella Tosi
submission deadline 20 Jan 2026 | Viewed by 265 | Submission Open
Keywords: critical care; extracorporeal organ support; critical care nephrology; cardiology; ARDS; sepsis; blood purification; liver support
(This special issue belongs to the Section Intensive Care)
Innovations in Infertility Treatment and Assisted Reproductive Technologies (ARTs)
edited by Diana Alecsandru
submission deadline 20 Jan 2026 | Viewed by 243 | Submission Open
Keywords: infertility; assisted reproductive technology (ARTs); fertility preservation; in vitro fertilization (IVF); reproductive endocrinology
(This special issue belongs to the Section Obstetrics & Gynecology)
Bronchoscopy and Interventional Pulmonology
edited by Bryan S. Benn and
submission deadline 20 Jan 2026 | Viewed by 239 | Submission Open
Keywords: navigation-guided bronchoscopy; Robotic-guided bronchoscopy; 3D imaging integration; lung nodule/peripheral pulmonary lesion marking; transbronchial lung cryobiopsy and interstitial lung disease; malignant and benign central airway obstruction and stenosis; airway stents; pleuroscopic procedures; bronchoscopic lung volume reduction
(This special issue belongs to the Section Respiratory Medicine)
Haemophilia: Current Treatment and Clinical Outcomes, Challenges and Opportunities: 2nd Edition
edited by
submission deadline 20 Jan 2026 | Viewed by 231 | Submission Open
Keywords: haemophilia A and B; FVIII EHL; FIX EHL; prophylaxis; emicizumab; health-related quality of life; population pharmacokinetics
(This special issue belongs to the Section Hematology)
From Dual Diagnosis to Dual Disorder(s): Bridging Comorbidity and Integrated Clinical Understanding submission deadline 20 Jan 2026 | Viewed by 210 | Submission Open
Keywords: dual diagnosis; dual disorder; psychiatric comorbidity; addiction; integrated care; self-medication; substance use; mental illness; treatment models
(This special issue belongs to the Section Mental Health)
Clinical Application of Echocardiography in Heart Disease: 2nd Edition
edited by
submission deadline 20 Jan 2026 | Viewed by 170 | Submission Open
Keywords: transthoracic echocardiography; transesophageal echocardiography; stress echocardiography; valve disease; coronary artery disease; myocardial disease; pericardial disease; aortic disease; congenital heart disease
(This special issue belongs to the Section Cardiology)
New Insights in Trauma and Emergency Surgery
edited by Kai Oliver Jensen and Valentin Neuhaus
submission deadline 20 Jan 2026 | Viewed by 161 | Submission Open
Keywords: trauma and emergency surgery; multiple trauma; orthopedic trauma; surgery; concepts in trauma
(This special issue belongs to the Section Emergency Medicine)
Preventive Strategies and Novel Treatments for Rheumatoid Arthritis
edited by
submission deadline 20 Jan 2026 | Viewed by 161 | Submission Open
Keywords: rheumatoid arthritis; antibodies; biologics; JAK; environment; susceptibility; therapeutic strategies
(This special issue belongs to the Section Immunology & Rheumatology)
Emerging Trends in Multiple Myeloma
edited by
submission deadline 20 Jan 2026 | Viewed by 157 | Submission Open
Keywords: multiple myeloma; personalized medicine; high-risk disease; cellular therapies; refractory disease
(This special issue belongs to the Section Hematology)
Recent Management of Hip Fractures
edited by
submission deadline 20 Jan 2026 | Viewed by 155 | Submission Open
Keywords: hip fracture; internal fixation; hemiarthroplasty; arthroplasty and fixation; osteoporosis management; fracture prevention; multidisciplinary care; surgical treatment; rehabilitation strategies
(This special issue belongs to the Section Orthopedics)
Therapeutic Strategies for Obesity and Diabetes in Cardiovascular Disease Patients
edited by Davide D'Andrea
submission deadline 20 Jan 2026 | Viewed by 152 | Submission Open
Keywords: obesity; diabetes; cardiovascular complications; diabetes management; pharmacological treatment; bariatric surgery; regular monitoring
(This special issue belongs to the Section Cardiovascular Medicine)
Advances in Chronic Pain Research and Therapy
edited by Elena Makovac
submission deadline 20 Jan 2026 | Viewed by 151 | Submission Open
Keywords: chronic pain; pain perception; brain-body interactions; therapeutic effectiveness; integrated approach
(This special issue belongs to the Section Clinical Rehabilitation)
Current Trends and Future Challenges in Heart Failure
edited by Oren Caspi and
submission deadline 20 Jan 2026 | Viewed by 147 | Submission Open
Keywords: heart failure; guideline-directed therapy; digital health; biomarkers; multidisciplinary care; artificial intelligence; cardiorenal syndrome; remote hemodynamic monitoring; cardiac amyloidosis; exercise rehabilitation
(This special issue belongs to the Section Cardiology)
Lung Transplantation: Current Challenges and New Perspectives
edited by Reinaldo E. Rampolla and Pedro A. Catarino
submission deadline 20 Jan 2026 | Viewed by 136 | Submission Open
Keywords: lung transplantation; interstitial lung diseases; pulmonary hypertension; chronic obstructive pulmonary disease; bronchiectasis; extra corporeal membrane oxygenation; robotic lung transplantation
(This special issue belongs to the Section Respiratory Medicine)
Clinical Update on Aortic Valve Disease Treatments
edited by
submission deadline 20 Jan 2026 | Viewed by 131 | Submission Open
Keywords: aortic valve disease; minimally invasive surgery; transcatheter procedures; echocardiography; diagnosis; therapy; innovation
(This special issue belongs to the Section Cardiology)
Regional Anesthesia in Pain Management
edited by Jaime L. Baratta
submission deadline 20 Jan 2026 | 1 articles | Viewed by 126 | Submission Open
Keywords: acute pain; perioperative medicine; general anesthesiology; regional anesthesia; orthopedic anesthesia; multimodal analgesia
(This special issue belongs to the Section Anesthesiology)
Clinical Advances, Opportunities, and Challenges in Digestive Diseases of the Foregut
edited by Valentin Mocanu and
submission deadline 20 Jan 2026 | Viewed by 125 | Submission Open
Keywords: obesity; achalasia; reflux; malrotation; therapeutic endoscopy
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Clinical Advances in Urologic Oncology: 2nd Edition
edited by Saum Ghodoussipour
submission deadline 20 Jan 2026 | Viewed by 117 | Submission Open
Keywords: bladder cancer; kidney cancer; prostate cancer; testis cancer; penile cancer; minimally invasive; cancer treatment
(This special issue belongs to the Section Nephrology & Urology)
Pulmonary Disease and Comorbidities, Clinical and Epidemiological Studies: From Neonates to Adults
edited by
submission deadline 20 Jan 2026 | Viewed by 114 | Submission Open
Keywords: pulmonary disorders; comorbidity; neonatal lung disease; pediatric pulmonology; adult respiratory disease; chronic respiratory conditions; clinical epidemiology; pulmonary function testing; diagnostic imaging; lung biomarkers; risk factors
(This special issue belongs to the Section Respiratory Medicine)
New Clinical Perception of Cardiac Rehabilitation
edited by and Mario Pacileo
submission deadline 20 Jan 2026 | Viewed by 114 | Submission Open
Keywords: cardiac rehabilitation; digital health; exercise therapy; cardiovascular prevention; chronic disease management; psychosocial support; personalized medicine
(This special issue belongs to the Section Clinical Rehabilitation)
Surgical Management of Vascular Diseases: Challenges and Innovations in the 21st Century
edited by Reinhardt T. Grundmann
submission deadline 20 Jan 2026 | Viewed by 105 | Submission Open
Keywords: abdominal aortic aneurysm; carotid stenosis; peripheral vascular disease; endovascular therapy; open surgery; vascular disease and cancer outcomes; clinical trial; meta-analysis; surgical innovation
(This special issue belongs to the Section Cardiovascular Medicine)
The Association Between Cancer and Cardiovascular Diseases: Insights After a Quarter of the Century
edited by Tomer Ziv-Baran and Elena Izkhakov
submission deadline 20 Jan 2026 | Viewed by 103 | Submission Open
Keywords: cancer survivors; cardiovascular disease; cardio-oncology; chemotherapy; radiation therapy; immunotherapy; multidisciplinary approach
(This special issue belongs to the Section Epidemiology & Public Health)
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