Current Trends and Future Challenges in Heart Failure
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Cardiology".
Deadline for manuscript submissions: 20 January 2026 | Viewed by 14
Special Issue Editors
Interests: heart failure; cardiomyopathies; cardiovascular organoids; causal inference machine learning in heart failure; myocardial regeneration
Special Issue Information
Dear Colleagues,
Heart failure (HF) remains a prominent cause of morbidity, mortality, and healthcare resource utilization globally. Its prevalence continues to escalate due to an aging population and the increasing incidence of comorbidities such as hypertension, diabetes, obesity, and chronic kidney disease. Despite significant advancements in diagnostic tools and the expansion of guideline-directed medical therapy, including novel therapies such as Angiotensin Receptor–Neprilysin Inhibitors (ARNIs) and Sodium-Glucose Cotransporter-2 (SGLT2) inhibitors, heart failure persists as a substantial clinical and public health challenge.
This Special Issue, titled "Current Trends and Future Challenges in Heart Failure," intends to furnish a comprehensive overview of the evolving landscape of HF. Topics slated for inclusion in this issue encompass emerging pharmacologic and advanced device-based therapies, the diagnosis and treatment of cardiac amyloidosis, inflammation-targeted therapies, precision-driven strategies such as biomarker-guided care, wearable biosensors, remote hemodynamic monitoring in HF management, and the integration of digital health with artificial intelligence.
Particular emphasis will be placed on enduring gaps in care, which include multidisciplinary approaches, the management of HF with preserved ejection fraction, cardiorenal syndrome, frailty, exercise rehabilitation, and disparities in access to therapies.
We invite original research articles and state-of-the-art reviews to promote interdisciplinary collaboration and enhance patient-centered care. By addressing current evidence and identifying priorities for future investigations, this issue aims to inform both clinical practice and research innovation in the management of HF.
Dr. Oren Caspi
Dr. Robert Zukermann
Guest Editors
Manuscript Submission Information
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Keywords
- heart failure
- guideline-directed therapy
- digital health
- biomarkers
- multidisciplinary care
- artificial intelligence
- cardiorenal syndrome
- remote hemodynamic monitoring
- cardiac amyloidosis
- exercise rehabilitation
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