Current Trends and Future Challenges in Heart Failure
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Cardiology".
Deadline for manuscript submissions: closed (20 January 2026) | Viewed by 822
Special Issue Editors
Interests: heart failure; cardiomyopathies; cardiovascular organoids; causal inference machine learning in heart failure; myocardial regeneration
Interests: acute and chronic heart failure; cardiomupahies; acute coronary syndrom; cardiac comorbidies; tachyarrhithmias
Special Issue Information
Dear Colleagues,
Heart failure (HF) remains a prominent cause of morbidity, mortality, and healthcare resource utilization globally. Its prevalence continues to escalate due to an aging population and the increasing incidence of comorbidities such as hypertension, diabetes, obesity, and chronic kidney disease. Despite significant advancements in diagnostic tools and the expansion of guideline-directed medical therapy, including novel therapies such as Angiotensin Receptor–Neprilysin Inhibitors (ARNIs) and Sodium-Glucose Cotransporter-2 (SGLT2) inhibitors, heart failure persists as a substantial clinical and public health challenge.
This Special Issue, titled "Current Trends and Future Challenges in Heart Failure," intends to furnish a comprehensive overview of the evolving landscape of HF. Topics slated for inclusion in this issue encompass emerging pharmacologic and advanced device-based therapies, the diagnosis and treatment of cardiac amyloidosis, inflammation-targeted therapies, precision-driven strategies such as biomarker-guided care, wearable biosensors, remote hemodynamic monitoring in HF management, and the integration of digital health with artificial intelligence.
Particular emphasis will be placed on enduring gaps in care, which include multidisciplinary approaches, the management of HF with preserved ejection fraction, cardiorenal syndrome, frailty, exercise rehabilitation, and disparities in access to therapies.
We invite original research articles and state-of-the-art reviews to promote interdisciplinary collaboration and enhance patient-centered care. By addressing current evidence and identifying priorities for future investigations, this issue aims to inform both clinical practice and research innovation in the management of HF.
Dr. Oren Caspi
Dr. Robert Zukermann
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- heart failure
- guideline-directed therapy
- digital health
- biomarkers
- multidisciplinary care
- artificial intelligence
- cardiorenal syndrome
- remote hemodynamic monitoring
- cardiac amyloidosis
- exercise rehabilitation
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
