Obesity-Related Metabolic and Cardiovascular Disorders
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Cardiovascular Medicine".
Deadline for manuscript submissions: 20 January 2026 | Viewed by 29
Special Issue Editors
2. Diabetes and Obesity Center, Garibaldi Hospital, Catania, Italy
Interests: insulin; adipose tissue; insulin resistance; type 2 diabetes mellitus; metabolism; bariatric surgery
Special Issue Information
Dear Colleagues,
Obesity has emerged as a global pandemic and serves as a primary driver of metabolic and cardiovascular complications. The complex interplay among obesity-related disorders—including insulin resistance, type 2 diabetes, dyslipidemia, hypertension, and cardiovascular disease—represents one of the most pressing challenges in contemporary medicine. These interconnected conditions share common pathophysiological pathways and amplify each other’s effects, creating a multifaceted clinical landscape that necessitates innovative, integrative approaches.
This Special Issue will focus specifically on obesity-related metabolic and cardiovascular disorders, exploring the mechanistic links that connect adipose tissue dysfunction with systemic metabolic disruption and cardiovascular pathology. We invite contributions that will advance our understanding of how obesity initiates and perpetuates these cascading health complications, while also presenting evidence-based solutions for its prevention and management.
This Special Issue will bring together multidisciplinary perspectives to address several critical areas:
- Adipose tissue dysfunction and its role in metabolic inflammation;
- Endothelial dysfunction and vascular complications in obesity;
- Health disparities and social determinants in obesity-related disorders;
- Epidemiological trends and health disparities in obesity-related disorders across diverse populations and geographic regions;
- Novel diagnostic approaches and biomarkers for early detection and more precise risk stratification;
- Integrated prevention strategies spanning lifestyle interventions, pharmacological approaches, and policy measures;
- Emerging therapeutic targets and personalized medicine approaches and their roles in modifying disease trajectories;
- Special considerations for vulnerable populations, including children, the elderly, and underserved communities.
By showcasing contributions from leading researchers and clinicians in endocrinology, cardiology, metabolism, public health, and related fields, this Special Issue will facilitate the cross-disciplinary collaboration that is essential in addressing the spectrum of obesity-related health challenges. The insights gleaned will inform the development of innovative approaches to the prevention, diagnosis, and management of obesity-related cardiometabolic dysfunction, ultimately improving global health and patient outcomes.
Prof. Dr. Lucia Frittitta
Dr. Federica Vinciguerra
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- obesity
- type 2 diabetes mellitus
- insulin resistance
- metabolic syndrome
- cardiovascular disease
- lipid disorder
- adipose tissue dysfunction
- visceral adiposity
- cardiometabolic risk
- endothelial dysfunction
- health disparities
- gut microbiota
- bariatric surgery
- precision medicine
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