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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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The Application of Mechanical Circulatory Support Within Cardiology Practice

edited by

Takami Yoshiyuki

submission deadline 20 May 2026 | Viewed by 55 | Submission Open

Keywords: mechanical circulatory support (MCS); cardiogenic shock; intra-aortic balloon pumping (IABP); extracorporeal membranous oxygenation (ECMO); Impella; ventricular assist device (VAD)

(This special issue belongs to the Section Cardiology)

Transcatheter Aortic Valve Implantation and Replacement: Prospects and Challenges—2nd Edition

edited by Konstantinos Toutouzas and

Panayotis Vlachakis

submission deadline 20 May 2026 | Viewed by 55 | Submission Open

Keywords: TAVI; aortic stenosis; valve-in-valve; structural heart disease; TAVI-in-TAVI

(This special issue belongs to the Section Cardiology)

Neurological Surgery: Clinical Advances and AI-Driven Innovations

edited by Ali A. Alattar

submission deadline 20 May 2026 | Viewed by 54 | Submission Open

Keywords: neurosurgery; artificial intelligence; machine learning; deep learning; radiomics; image segmentation; surgical video analytics; navigation and robotics; predictive modeling; clinical decision support

(This special issue belongs to the Section Clinical Neurology)

Contemporary Advances in Joint Arthroplasty: Optimizing Outcomes and Expanding Indications

edited by

Ashim Gupta

and

Hugo C. Rodriguez

submission deadline 20 May 2026 | Viewed by 53 | Submission Open

Keywords: joint arthroplasty; total joint replacement; revision arthroplasty; robotic-assisted surgery; periprosthetic joint infection (PJI); enhanced recovery after surgery (ERAS); machine learning; artifical intelligence

(This special issue belongs to the Section Orthopedics)

Valvular Heart Disease: Current Knowledge and Therapeutic Prospects

edited by Simona Mega

submission deadline 20 May 2026 | Viewed by 48 | Submission Open

Keywords: valvular heart disease; echocardiographic assessment; cardiovascular imaging; valvular regurgitation; valvular stenosis; structural heart intervention; minimally invasive cardiac surgery; catheter-based interventions

(This special issue belongs to the Section Cardiology)

Bladder Cancer: Diagnosis, Treatment and Future Opportunities

edited by

Jørgen Bjerggaard Jensen

submission deadline 20 May 2026 | Viewed by 47 | Submission Open

Keywords: urology; bladder cancer; urothelial cancer; non-muscle invasive bladder cancer; muscle invasive bladder cancer

(This special issue belongs to the Section Nephrology & Urology)

The Interplay of Trauma Symptoms and Cognitive Functioning: Clinical Implications

edited by

Jonathan Guez

and

Rotem Saar

submission deadline 20 May 2026 | Viewed by 41 | Submission Open

Keywords: trauma; stress; cognitive dysfunction; clinical syndromes; clinical implications

(This special issue belongs to the Section Mental Health)

Clinical Challenges in Uterus Transplant Management

edited by Giuliano Testa

submission deadline 20 May 2026 | Viewed by 39 | Submission Open

Keywords: uterus transplant; absolute uterine infertility; fertility treatment; immunosuppression in uterus transplant; pregnancy complications; uterine donor evaluation

(This special issue belongs to the Section Obstetrics & Gynecology)

Current Understanding and Management of Asthma and Chronic Obstructive Pulmonary Disease

edited by Josuel Ora

submission deadline 20 May 2026 | Viewed by 37 | Submission Open

Keywords: asthma; chronic obstructive pulmonary disease (COPD); personalized medicine; exacerbations; biomarkers; inhalation therapy; digital health; artificial intelligence; pulmonary rehabilitation; comorbidities

(This special issue belongs to the Section Respiratory Medicine)

Audiology and Phoniatrics in Head and Neck Surgery: Functional Assessment, Rehabilitation Strategies, and Quality of Life Outcomes

edited by

Claudia Cassandro

submission deadline 20 May 2026 | Viewed by 31 | Submission Open

Keywords: audiology; phoniatrics; voice disorders; hearing preservation; speech rehabilitation; head and neck surgery; functional outcomes; quality of life; voice analysis; audiometry; cochlear implants; dysphagia; laryngeal surgery

(This special issue belongs to the Section Otolaryngology)

Osteoporosis: A Renascent Impact of Vertebral Fractures in the Diagnosis and Management

edited by Csaba Horvath

submission deadline 20 May 2026 | Viewed by 29 | Submission Open

Keywords: osteoporosis; vertebral fractures; imminent fracture risk; FRAX; bone densitometry; vertebral fracture assessment

(This special issue belongs to the Section Orthopedics)

Clinical Advances in Venous Thrombosis

edited by Nicola Mumoli

submission deadline 20 May 2026 | Viewed by 6 | Submission Open

Keywords: direct oral anticoagulants (DOACs); cancer-associated thrombosis (CAT); venous thromboembolism (VTE); thrombolytic therapy; post-thrombotic syndrome (PTS); artificial intelligence in VTE prediction

(This special issue belongs to the Section Vascular Medicine)

Clinical Features and Management of Psychosis

edited by

Maria Margariti

George Konstantakopoulos

and Michael Hadjulis

submission deadline 22 May 2026 | 4 articles | Viewed by 10049 | Submission Open

Keywords: psychosis; clinical features of psychosis; diagnosis of psychosis; schizophrenia; psychotic depression; affective disorder with psychotic features; psychosis in substance use disorders; psychosis in neurological disorders; psychosis in medical conditions; management of psychosis; treatment of psychosis

(This special issue belongs to the Section Mental Health)

Thoracic Surgery: Recent Developments and Future Challenges

edited by

Marco Andolfi

and Lucio Cagini

submission deadline 22 May 2026 | 1 articles | Viewed by 2767 | Submission Open

Keywords: VATS; RATS; ERAS; sublobar resection; minimally invasive thoracic surgery; target therapy; nodule localization

(This special issue belongs to the Section Respiratory Medicine)

Clinical Updates on Rheumatoid Arthritis: 2nd Edition

edited by Francesca Bandinelli

submission deadline 22 May 2026 | 1 articles | Viewed by 1571 | Submission Open

Keywords: rheumatoid arthritis; rheumatology; treatment; diagnosis; biomarkers; rheumatic disease

(This special issue belongs to the Section Immunology & Rheumatology)

Thrombotic Risk and Its Management Across Diverse Clinical Settings

edited by Samuel Bogdan Todor and Ana Maria Vlǎdǎreanu

submission deadline 22 May 2026 | 1 articles | Viewed by 1532 | Submission Open

Keywords: thrombosis; thrombotic risk; hematologic disorders; thrombophilia; myeloproliferative neoplasms; antithrombotic therapy; cardiovascular diseases; biomarkers

(This special issue belongs to the Section Hematology)

Takotsubo Syndrome: Insights into Pathophysiology, Diagnosis, and Management

edited by

Andreas Mitsis

and

Nikolaos Kadoglou

submission deadline 22 May 2026 | Viewed by 280 | Submission Open

Keywords: takotsubo syndrome; stress cardiomyopathy; acute heart failure; cardiac imaging; catecholamine surge; myocardial dysfunction; echocardiography; biomarker discovery; cardiovascular risk; clinical management

(This special issue belongs to the Section Cardiology)

Role of Platelet in Inflammation, Infection, and Immune Response

edited by

Amir Houshang Shemirani

submission deadline 22 May 2026 | Viewed by 198 | Submission Open

Keywords: platelets; platelet count; dual antiplatelet therapy; inflammation; thrombosis; inflammation; hemostasis; immune response

(This special issue belongs to the Section Hematology)

Clinical Pharmacology: Adverse Drug Reactions

edited by

Andrej Belančić

and Ivana Mudnić

submission deadline 25 May 2026 | 6 articles | Viewed by 23277 | Submission Open

Keywords: pharmacology; adverse drug reactions; drug interactions; pharmacovigilance; drug safety

(This special issue belongs to the Section Pharmacology)

Ventilation in Critical Care Medicine: 2nd Edition

edited by Gianluca Zani

submission deadline 25 May 2026 | 3 articles | Viewed by 15082 | Submission Open

Keywords: invasive ventilation; non-invasive ventilation; acute respiratory failure; best PEEP; respiratory weaning; respiratory mechanics; ventilation and perfusion; personalized ventilation

(This special issue belongs to the Section Intensive Care)

The Association Between Sleep Disorders and Metabolic and Mental Health

edited by

Filip Franciszek Karuga

Piotr Bialasiewicz

and

Marcin Sochal

submission deadline 25 May 2026 | 5 articles | Viewed by 11648 | Submission Open

Keywords: sleep medicine; sleep apnea; hypoxia; metabolism; mental health; women’ s health

(This special issue belongs to the Section Mental Health)

Maxillo-Facial Surgery: New Insights and Technologies in Head and Neck

edited by Federica Ruggiero

submission deadline 25 May 2026 | 6 articles | Viewed by 11495 | Submission Open

Keywords: oral and maxilla-facial surgery; orthognathic surgery; cranio-facial surgery; head and neck surgery; augmented reality; navigation; finite element modeling; virtual surgical planning; patient-specific implants

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Preventive, Diagnostic and Therapeutic Strategies for Abdominal Surgery Complications (Second Edition)

edited by

Orestis Ioannidis

submission deadline 25 May 2026 | 5 articles | Viewed by 9218 | Submission Open

Keywords: complications; diagnosis; treatment; management; morbidity; abdomen; abdominal surgery; outcome; postoperative

(This special issue belongs to the Section General Surgery)

Oral and Maxillofacial Surgery: Diagnosis, Management and Future Opportunities

edited by

Federico Gelpi

submission deadline 25 May 2026 | 5 articles | Viewed by 8318 | Submission Open

Keywords: head and neck oncology; free flaps; oral surgery; malformative surgery; traumatology; endoscopy; preprosthetic surgery; reconstructive surgery; vascular malformations; osteonecrosis

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Clinical Diagnosis and Management of Vestibular Disorders

edited by

Sinisa Maslovara

, Mario Habek and

Andro Košec

submission deadline 25 May 2026 | 7 articles | Viewed by 7714 | Submission Open

Keywords: vertigo; dizziness; epidemiology; genetics; diagnostics; management

(This special issue belongs to the Section Otolaryngology)

Clinical Utility of Optical Coherence Tomography in Ophthalmology: 2nd Edition

edited by

Jose Ignacio Fernandez-Vigo

submission deadline 25 May 2026 | 4 articles | Viewed by 7036 | Submission Open

Keywords: optical coherence tomography; ophthalmology; intraoperative OCT; en face OCT; wide-field OCT; retinal diseases; glaucoma; cornea; strabismus; cataract

(This special issue belongs to the Section Ophthalmology)

Future Opportunities in Thoracic Surgery: The Cutting Edge: 2nd Edition

edited by

Giulio Maurizi

submission deadline 25 May 2026 | 2 articles | Viewed by 5568 | Submission Open

Keywords: surgical resection; immunotherapy; target therapy; thoracic surgery; thoracic oncology; lung cancer

(This special issue belongs to the Section Respiratory Medicine)

Novel Insights into the Diagnosis and Management of Inflammatory Bowel Disease (IBD)

edited by

Alina Ioana Tantau

submission deadline 25 May 2026 | 4 articles | Viewed by 3964 | Submission Open

Keywords: inflammatory bowel disease; non-invasive biomarkers; abdominal ultrasonography; colonoscopy; biologic therapy; small molecules; mucosal healing; brain-gut axis; dysbiosis; colorectal dysplasia

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Assisted Reproductive Technology and Infertility Treatment: Current Updates and Perspectives—2nd Edition

edited by Nikos Nikolettos and

Angeliki Tiptiri-Kourpeti

submission deadline 25 May 2026 | 3 articles | Viewed by 3577 | Submission Open

Keywords: assisted reproduction technology (ART); infertility; treatment; reproduction; IVF

(This special issue belongs to the Section Reproductive Medicine & Andrology)

The Rebirth of Ventral Skull Base Surgery through Multiportal Approaches: Endonasal, Transorbital, Transmaxillary and Transoral Routes

edited by Matteo de Notaris and Francesco Corrivetti

submission deadline 25 May 2026 | 3 articles | Viewed by 2596 | Submission Open

Keywords: skull base surgery; neuroendoscopy; neuroanatomy; multiportal approaches; technical advancements

(This special issue belongs to the Section Clinical Neurology)

Clinical Highlights in Uveal Melanoma

edited by Tomasz Chorągiewicz and

Joanna Dolar-Szczasny

submission deadline 25 May 2026 | 1 articles | Viewed by 2251 | Submission Open

Keywords: choroidal melanoma; uveal melanoma; radiotherapy; enucleation; brachytherapy

(This special issue belongs to the Section Ophthalmology)

Interstitial Lung Disease Secondary to Autoimmune Disorders: Recent Advances and Novel Perspectives

edited by

Gaetano La Rocca

Gianluca Sambataro

and Francesco Ferro

submission deadline 25 May 2026 | 1 articles | Viewed by 1914 | Submission Open

Keywords: interstitial lung disease; lung involvement; connective tissue diseases; rheumatoid arthritis; systemic vasculitis; radiomics; lung ultrasound; biomarkers; pathogenetic immunological pathways; therapeutic targets

(This special issue belongs to the Section Respiratory Medicine)

Advances in the Clinical Management of Perioperative Anesthesia: 2nd Edition

edited by Alessia Mattei, Rita Cataldo and

Alessandro Strumia

submission deadline 25 May 2026 | 3 articles | Viewed by 1754 | Submission Open

Keywords: perioperative outcomes (surgical; anesthetic; medical); evidence-based care; perioperative guidelines and consensus statements; preoperative evaluation and risk scores; preoperative testing; surgical optimization and enhanced surgical recovery programs; intensive care unit

(This special issue belongs to the Section Anesthesiology)

Current Clinical Advances in Urinary Incontinence

edited by Adolf Lukanovic, David Lukanović and Mija Blaganje

submission deadline 25 May 2026 | 2 articles | Viewed by 1552 | Submission Open

Keywords: female urinary incontinence; stress urinary incontinence; overactive bladder; diagnosis; prevention; conservative treatment; minimally invasive treatment; surgery; mid-urethral sling; new approach; energy-based devices

(This special issue belongs to the Section Nephrology & Urology)

Innovative Technologies and Approaches in Eye Disease Management and Refractive Surgery

edited by

Hidenaga Kobashi

submission deadline 25 May 2026 | 1 articles | Viewed by 1458 | Submission Open

Keywords: multifocal intraocular lenses; femtosecond lasers; artificial intelligence; imaging; eye surgery; refractive surgery

(This special issue belongs to the Section Ophthalmology)

Diabetic Foot: Emerging Prevention Strategies and Epidemiology

edited by

Vilma Urbančič-Rovan

submission deadline 25 May 2026 | 1 articles | Viewed by 1224 | Submission Open

Keywords: diabetic foot; foot clinics; epidemiology; prevention; screening; amputation; podiatry

(This special issue belongs to the Section Endocrinology & Metabolism)

Clinical Updates in Reproductive Endocrinology: 2nd Edition

edited by Iwona Bojar and

Dorota Raczkiewicz

submission deadline 25 May 2026 | 1 articles | Viewed by 1191 | Submission Open

Keywords: reproductive endocrinology; endocrine diseases in pregnancy; infertility; endocrine diagnostics in infertility; long-term consequences of endocrine disorders; therapy for endocrine disorders

(This special issue belongs to the Section Obstetrics & Gynecology)

Approaches and Challenges in Oral Rehabilitation

edited by

Yoko Hasegawa

and Takayuki Kosaka

submission deadline 25 May 2026 | 1 articles | Viewed by 1110 | Submission Open

Keywords: oral rehabilitation; oral health; systemic health; dental innovation; neuroplasticity

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Advances in Maxillofacial Surgery—Historical and Future Perspectives and Controversies

edited by

Kamil Nelke

Maciej Dobrzyński

and

Michał Gontarz

submission deadline 25 May 2026 | 1 articles | Viewed by 1106 | Submission Open

Keywords: oral oncology; facial skeleton; oral cavity; surgical approaches; head and neck; parotid tumors; jaw cysts and tumors; bone healing; patient-specific solutions; surgery planning; artificial intelligence; soft tissues; cancers and tumors of the oral cavity; microsurgery perspectives; open surgery; endoscopic surgery; trauma surgery; facial traumatology; bone and soft tissues healing after trauma; jaw deformities; orthognathic surgery today and tomorrow

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Autoimmune-Induced Alopecia and Emerging Therapies in Hair Loss—2nd Edition

edited by David Saceda-Corralo

submission deadline 25 May 2026 | 2 articles | Viewed by 623 | Submission Open

Keywords: autoimmune-induced alopecia; alopecia areata; cicatricial alopecia; occurs; hair loss; frontal fibrosing alopecia

(This special issue belongs to the Section Dermatology)

New Insights in Paediatric Endocrinology

edited by

Marco Fiore

submission deadline 25 May 2026 | 1 articles | Viewed by 571 | Submission Open

Keywords: endocrinology; pediatrics; hormones; therapy and treatment; adolescents; newborns

(This special issue belongs to the Section Clinical Pediatrics)

Interstitial Lung Diseases: New Treatments Based on Treatable Traits

edited by Francesco Amati

submission deadline 25 May 2026 | 1 articles | Viewed by 570 | Submission Open

Keywords: interstitial lung diseases; progressive pulmonary fibrosis; phenotypes; endotypes; treatment; precision medicine

(This special issue belongs to the Section Respiratory Medicine)

Transcatheter Aortic Valve Implantation- Clinical Management and Future Challenges

edited by Mohamed Farag

submission deadline 25 May 2026 | 1 articles | Viewed by 523 | Submission Open

Keywords: transcatheter aortic valve implantation; TAVI; bicuspid aortic valve; small annulus; prosthesis– patient mismatch; coronary reaccess; valve-in-valve TAVI; leaflet modification

(This special issue belongs to the Section Cardiovascular Medicine)

Multiple Sclerosis and Demyelinating Disease: Clinical Treatment and Management

edited by Sotirios Giannopoulos

submission deadline 25 May 2026 | 1 articles | Viewed by 386 | Submission Open

Keywords: multiple sclerosis; demyelinating disease; comorbidities; disease modifying treatments; neuromuscular disorder; myasthenia gravis

(This special issue belongs to the Section Clinical Neurology)

New Advances in Congenital Heart Disease

edited by

Efrén Martínez-Quintana

submission deadline 25 May 2026 | 1 articles | Viewed by 369 | Submission Open

Keywords: congenital heart disease; pediatric cardiology; adult congenital heart disease; cardiac surgery; interventional cardiology; long-term outcomes; cardiac imaging

(This special issue belongs to the Section Cardiology)

Anemia: Clinical Updates in Diagnosis, Management, and Treatment

edited by

Joan-Lluis Vives-Corrons

submission deadline 25 May 2026 | 1 articles | Viewed by 333 | Submission Open

Keywords: anemia; diagnostic tools; hematology; artificial intelligence; targeted therapy; hereditary hemolytic anemia

(This special issue belongs to the Section Hematology)

Current Perspectives on the Clinical Management of Respiratory Diseases

edited by

Pradeesh Sivapalan

and

Alexandr Ceasovschih

submission deadline 25 May 2026 | 1 articles | Viewed by 217 | Submission Open

Keywords: COPD; acute exacerbations; biomarkers; clinical trials; bronchiectasis; respiratory infections

(This special issue belongs to the Section Respiratory Medicine)

Advances in Ablation Therapy for Atrial Fibrillation: Innovations and Clinical Applications

edited by Ioanna Koniari

submission deadline 25 May 2026 | Viewed by 212 | Submission Open

Keywords: atrial fibrillation; ablation; PFA; PVI; non-thermal energy; mapping system

(This special issue belongs to the Section Cardiology)

High-Risk Neuroblastoma and Rhabdoid Tumors: New Clinical Insights and Challenges (Second Edition)

edited by

Rupert Handgretinger

and Johannes Hubertus Schulte

submission deadline 25 May 2026 | Viewed by 166 | Submission Open

Keywords: neuroblastoma; rhabdoid tumor; autologous stem cell transplantation; allogeneic stem cell transplantation immunotherapy; anti-GD2 antibody; targeted therapy; CAR T-cells

(This special issue belongs to the Section Oncology)

Surgical Innovation and Clinical Outcomes in Plastic and Reconstructive Surgery

edited by Pari Naz Mohanna and Ayush Kapila

submission deadline 25 May 2026 | Viewed by 84 | Submission Open

Keywords: plastic and reconstructive surgery; microsurgery; breast reconstruction; surgical innovation; novel flap techniques

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Displaying special issue 1201-1250 on page 25 of 31.

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