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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in Diagnosis and Management of Pancreatobiliary Disorders—2nd Edition

edited by

Francesca Lodato

submission deadline 9 Jan 2026 | 3 articles | Viewed by 2928 | Submission Open

Keywords: pancreas diseases; pancreatic tumors; biliary tract diseases and neoplams; ERCP; EUS; cholangioscopy

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

New Clinical Advances in Pancreatobiliary Diseases

edited by

Kyong Joo Lee

submission deadline 9 Jan 2026 | 1 articles | Viewed by 773 | Submission Open

Keywords: pancreatobiliary diseases; EUS; ERCP; interventional endoscopy; targeted therapy; pancreatobiliary cancer

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

New Advance in Chronic Total Occlusion Percutaneous Coronary Intervention

edited by Anbukarasi Maran and Kevin Croce

submission deadline 9 Jan 2026 | Viewed by 124 | Submission Open

Keywords: chronic total occlusion (CTO); percutaneous coronary intervention (PCI); innovative techniques; guidewire technology; retrograde PCI; interventional cardiology

(This special issue belongs to the Section Cardiovascular Medicine)

Heart Disease and Chronic Inflammatory Conditions: New Insights

edited by Ofer Kobo and Gilad Margolis

submission deadline 10 Jan 2026 | 4 articles | Viewed by 12393 | Submission Open

Keywords: heart diseases; chronic inflammatory; rheumatoid arthritis; cardiovascular disease; inflammatory bowel disease

(This special issue belongs to the Section Cardiology)

Clinical Guidelines in Critical Care Medicine

edited by

Ana Vujaklija Brajković

Andrej Markota

and Daniela Bandic-Pavlovic

submission deadline 10 Jan 2026 | 3 articles | Viewed by 5925 | Submission Open

Keywords: critical illness; immunocompromised host; biomarkers; thrombocytopenia; blood coagulation disorders; multiple trauma; diagnostic imaging

(This special issue belongs to the Section Intensive Care)

Heart Failure and Coronary Artery Diseases: Cardiovascular Complications and Comorbidities

edited by

Dhrubajyoti Bandyopadhyay

Vikash Jaiswal

and

Adrija Hajra

submission deadline 10 Jan 2026 | 3 articles | Viewed by 3965 | Submission Open

Keywords: heart failure; acute myocardial infarction; coronary artery diseases; cardiac imaging; biomarkers; artificial intelligence

(This special issue belongs to the Section Cardiovascular Medicine)

From Acute Injury to Personalized Prevention—Developing Modern Strategies

edited by

Markus Gesslein

and

Eduard Kurz

submission deadline 10 Jan 2026 | 2 articles | Viewed by 1838 | Submission Open

Keywords: orthopedics; acute injury; personalized prevention; innovative methodologies; musculoskeletal disorders; musculoskeletal injury; conservative therapy; functional testing; intervention

(This special issue belongs to the Section Orthopedics)

Advancements in Spinal Oncology: The Current Landscape

edited by Aladine Elsamadicy and

Daniel M. Sciubba

submission deadline 10 Jan 2026 | 1 articles | Viewed by 1799 | Submission Open

Keywords: spinal oncology; patient outcomes; primary bone tumor; spine metastases; intradural tumors

(This special issue belongs to the Section Clinical Neurology)

Advanced Physiotherapy Practice in Patients with Musculoskeletal Disorders

edited by

Filippo Maselli

and

Firas Mourad

submission deadline 10 Jan 2026 | Viewed by 154 | Submission Open

Keywords: differential diagnosis; physiotherapy; rehabilitation; multidisciplinary; effectiveness; musculoskeletal disorders; screening for referral; manual therapy; exercise; cognitive behavioral therapy; pain neuroscience

(This special issue belongs to the Section Clinical Rehabilitation)

Pelvic Organ Prolapse: Clinical Advances and Challenges

edited by

Barbara Bodner-Adler

submission deadline 10 Jan 2026 | Viewed by 150 | Submission Open

Keywords: pelvic organ prolapse; pessary treatment; uterus-preserving prolapse surgery; clinical management; clinical treatment

(This special issue belongs to the Section Obstetrics & Gynecology)

Advances in Vascular and Endovascular Surgery: Second Edition

edited by

Fadi Taher

and Afshin Assadian

submission deadline 11 Jan 2026 | 4 articles | Viewed by 3155 | Submission Open

Keywords: vascular surgery; endovascular surgery; aortic surgery; peripheral arterial disease; vascular imaging; EVAR; FEVAR; vascular access; vascular education; aneurysms

(This special issue belongs to the Section Vascular Medicine)

Clinical Updates in Physiotherapy for Musculoskeletal Disorders

edited by

Santiago Navarro Ledesma

submission deadline 15 Jan 2026 | 10 articles | Viewed by 25211 | Submission Open

Keywords: musculoskeletal disorders; physiotherapy interventions; lifestyle; psychoneuroimmunology; chronic pain; inflammation; physical therapy

(This special issue belongs to the Section Clinical Rehabilitation)

Physical Therapy in Neurorehabilitation

edited by

Marianna Papadopoulou

and

George K. Papadimas

submission deadline 15 Jan 2026 | 8 articles | Viewed by 20319 | Submission Open

Keywords: physical therapy; transcutaneous electrical nerve stimulation (TENS); muscle strengthening; balance exercising; pain; quality of life; neurodegenerative disorders; neuromuscular disorders; stroke; demyelinating disorders

(This special issue belongs to the Section Clinical Neurology)

Innovative Systemic Treatments for Atopic Dermatitis

edited by

Luigi Gargiulo

submission deadline 15 Jan 2026 | 5 articles | Viewed by 15197 | Submission Open

Keywords: atopic dermatitis; atopic eczema; JAK inhibitors; anti-IL-4; anti-IL-13; dupilumab; tralokinumab; lebrikizumab; abrocitinib; upadacitinib; baricitinib

(This special issue belongs to the Section Dermatology)

Clinical Application of Biomarkers in Cancers

edited by

Monica Florescu

submission deadline 15 Jan 2026 | 3 articles | Viewed by 13431 | Submission Open

Keywords: cancer biomarkers; early detection; personalized therapy; biomarker validation; advanced technologies; clinical implementation

(This special issue belongs to the Section Clinical Laboratory Medicine)

Current Trends and Prospects of Critical Emergency Medicine

edited by Quincy K. Tran

submission deadline 15 Jan 2026 | 8 articles | Viewed by 7793 | Submission Open

Keywords: critically ill patients; critical care; resuscitation; emergency medicine; trends; prospects; outcomes

(This special issue belongs to the Section Emergency Medicine)

Advances in Pulmonary Disease Management and Innovation in Treatment

edited by

Monica Steluța Marc

and

Florin Mihaltan

submission deadline 15 Jan 2026 | 4 articles | Viewed by 6173 | Submission Open

Keywords: severe asthma; COPD; sleep-related breathing disorders; respiratory tract infections; innovative respiratory therapies; translational pulmonary research; pulmonary vascular disease; interstitial lung disease; eHealth in respiratory care

(This special issue belongs to the Section Respiratory Medicine)

Clinical Advances in Assessment Measures and Theoretical Models of Caregivers' Sensitivity and Contingency: 2nd Edition

edited by

Silvia Cimino

submission deadline 15 Jan 2026 | 3 articles | Viewed by 4622 | Submission Open

Keywords: clinical caregiving; sensitivity assessment; contingency modeling; caregiver– patient interactions; mental health outcomes; novel assessment measures; therapeutic responsiveness; caregiver interventions; clinical well-being; care recipient support

(This special issue belongs to the Section Intensive Care)

Pulmonary Embolism—Current and Novel Approaches

edited by Roy Beigel and Shlomi Matetzky

submission deadline 15 Jan 2026 | 3 articles | Viewed by 4312 | Submission Open

Keywords: pulmonary embolism; treatment; coagulation; venous thrombosis; thrombolysis; anticoagulation; risk stratification

(This special issue belongs to the Section Respiratory Medicine)

Clinical Advances in Minimally Invasive Urologic Surgery

edited by

Umberto Carbonara

, Fabio Crocerossa and

Savio Domenico Pandolfo

submission deadline 15 Jan 2026 | 3 articles | Viewed by 3767 | Submission Open

Keywords: urology; uro-oncology; uro-gynecology; robotic surgery; laparoscopy; robot-assisted; artificial intelligence

(This special issue belongs to the Section Nephrology & Urology)

Safety in Spinal Surgery

edited by Simon B. Roberts and

Thanos Tsirikos

submission deadline 15 Jan 2026 | 1 articles | Viewed by 3738 | Submission Open

Keywords: spinal surgery; patients with spinal deformity; inherent risks; risk management; surgery safety

(This special issue belongs to the Section General Surgery)

Clinical Management and Treatment of Psoriasis

edited by

Luciano Ibba

submission deadline 15 Jan 2026 | 2 articles | Viewed by 3262 | Submission Open

Keywords: psoriasis; biological drugs; personalized medicine; comorbidities; real-world evidence

(This special issue belongs to the Section Dermatology)

Clinical Advances in the Diagnosis and Treatment of Cardiac Arrhythmias

edited by Fabrizio Guarracini and

Marisa Varrenti

submission deadline 15 Jan 2026 | 3 articles | Viewed by 2771 | Submission Open

Keywords: cardiac arrhythmias; antiarrhythmic agents; pacemakers; cardiac resynchronization; catheter ablation; electrophysiology

(This special issue belongs to the Section Cardiology)

Up-to-Date Research in Liver Transplantation

edited by

Pierluigi Toniutto

submission deadline 15 Jan 2026 | 1 articles | Viewed by 2312 | Submission Open

Keywords: liver transplantation; acute or chronic liver diseases; hepatitis C virus infection; hepatocellular carcinoma (HCC); cirrhosis; intrahepatic (ICCA); perihilar (PCCA) cholangiocarcinoma; unresectable liver metastases; acute or chronic liver failure (ACLF); acute alcoholic hepatitis (AAH)

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Diagnosis and Management of Aortic Diseases: Drafting from Theoretical Aspects to Clinical Practice—2nd Edition

edited by

Mario D’Oria

submission deadline 15 Jan 2026 | 2 articles | Viewed by 1831 | Submission Open

Keywords: aortic disease; aortic aneurysm; aortic dissection; aortic surgery; diagnosis and management

(This special issue belongs to the Section Cardiovascular Medicine)

Pediatric Nephrology: Advances in the Diagnosis and Management of Pediatric Kidney Disorders

edited by

Agnieszka Rybi-Szumińska

and

Anna Maria Wasilewska

submission deadline 15 Jan 2026 | 2 articles | Viewed by 1602 | Submission Open

Keywords: diagnosis; management; treatment; kidney disorders; chronic kidney disease; biomarkers; genetic testing; kidney; children; newborn

(This special issue belongs to the Section Nephrology & Urology)

Recent Clinical Advances in Percutaneous Coronary Intervention

edited by

Lampson Fan

and Luke Pickup

submission deadline 15 Jan 2026 | 2 articles | Viewed by 1404 | Submission Open

Keywords: complex PCI; calcium modification; left main stem; stent; coronary artery disease; atherectomy; mechanical circula-tory support device; Impella; DCB; intra-coronary imaging; IVUS; OCT

(This special issue belongs to the Section Cardiology)

Intracranial Hemorrhage: Advances in Diagnosis, Management and Treatment

edited by Hitoshi Fukuda

submission deadline 15 Jan 2026 | 1 articles | Viewed by 909 | Submission Open

Keywords: intracerebral hemorrhage; subarachnoid hemorrhage; traumatic hemorrhage; prehospital care; less invasive surgery; vascular malformation; antihypertensive drug; intracranial pressure elevation; decompressive craniectomy; neurocritical care; nursing care; rehabilitation

(This special issue belongs to the Section Clinical Neurology)

Pediatric Urology: How to Adapt Current Knowledge to the New Era

edited by Simona Gerocarni Nappo and

Elisa Cerchia

submission deadline 15 Jan 2026 | Viewed by 426 | Submission Open

Keywords: pediatric urology; telemedicine; telesurgery; artificial intelligence; 3D-models; congenital urinary diseases; pediatric oncology

(This special issue belongs to the Section Clinical Pediatrics)

Advances in Oculoplastic Surgery and Ocular Surface Diseases

edited by Michael T. Yen, Francesco Quaranta Leoni and

Balestrazzi Alessandra

submission deadline 15 Jan 2026 | Viewed by 203 | Submission Open

Keywords: ocular surface disease; corneal neurotization; neurotrophic keratopathy; eyelid malposition; facial nerve palsy; thyroid eye disease; oculoplastic surgery; hemocomponents; dry anophthalmic socket; corneal pathology; ocular surface reconstruction; exposure keratopathy

(This special issue belongs to the Section Ophthalmology)

Chronic Kidney Disease: Current Challenges and Adverse Outcomes

edited by

Diana Tania Luminița Moldovan

and Flaviu Bob

submission deadline 15 Jan 2026 | Viewed by 156 | Submission Open

Keywords: chronic kidney disease; CKD progression; hemodialysis; cardiovascular complications; vascular calcification; lifestyle; nutrition; bone and mineral disorders; CKD-associated osteoporosis; mortality

(This special issue belongs to the Section Nephrology & Urology)

Advances in Minimally Invasive Cardiothoracic Surgery: Current Techniques and Future Innovations

edited by

Akshay Kumar

and

Mohamed Rahouma

submission deadline 15 Jan 2026 | Viewed by 146 | Submission Open

Keywords: cardiothoracic surgery; lung cancer; cardiac imaging; minimally invasive surgery; thoracic oncology

(This special issue belongs to the Section Cardiovascular Medicine)

Pulmonary Critical Care: Diagnosis and Treatment of Respiratory System Diseases

edited by Yaron Bar-Lavie

submission deadline 15 Jan 2026 | Viewed by 139 | Submission Open

Keywords: acute respiratory distress syndrome (ARDS); mechanical ventilation; chronic obstructive pulmonary disease (COPD); sepsis-induced lung injury; pulmonary fibrosis; bronchoscopy in critical care

(This special issue belongs to the Section Intensive Care)

Insights into Acute Pancreatitis: Pathogenesis, Diagnosis, and Management

edited by Gil Nissim Bachar and Ram Dickman

submission deadline 15 Jan 2026 | Viewed by 134 | Submission Open

Keywords: acute pancreatitis; pancreatic inflammation; necrotizing pancreatitis; clinical outcomes; ultrasound examination

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Clinical Updates on Epilepsy Researches

edited by

Guillermo Estivill-Torrús

submission deadline 15 Jan 2026 | Viewed by 130 | Submission Open

Keywords: epilepsy; autoimmune epilepsy; neural autoantibodies; seizure disorders; experimental epilepsy models; animal studies; neuronal excitability; immunotherapy; predictive scoring systems; epilepsy biomarkers

(This special issue belongs to the Section Clinical Neurology)

Artificial Intelligence in Gastrointestinal Disorders: Current Updates from Theory to Clinical Practice

edited by

Maria Pina Dore

and

Elettra Merola

submission deadline 15 Jan 2026 | Viewed by 126 | Submission Open

Keywords: artificial intelligence; gastroenterology; medical imaging; endoscopy; prognostic modeling; ethical considerations

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Clinical Diagnosis and Management of Chronic Venous Diseases

edited by

Sigitas Urbonavičius

submission deadline 15 Jan 2026 | Viewed by 95 | Submission Open

Keywords: varicose veins; chronic venous insufficiency; pathogenesis; operative treatment; conservative treatment; profilaxis

(This special issue belongs to the Section Vascular Medicine)

Novel Sepsis and Post-Sepsis Care: The Heart and Beyond

edited by Alexander Liu and

Barbara J. Philips

submission deadline 16 Jan 2026 | Viewed by 244 | Submission Open

Keywords: sepsis; post sepsis; inflammation; cardiomyopathy; heart failure; cardiac imaging; biomarkers; novel therapies; prognosis; clinical outcomes

Innovations in Plastic and Reconstructive Research

edited by Damiano Tambasco and Roberta Albanese

submission deadline 18 Jan 2026 | 4 articles | Viewed by 5944 | Submission Open

Keywords: microvascular surgery; 3D printing; regenerative medicine; aesthetic surgery; minimally invasive techniques

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

New Advances in Hip and Knee Arthroplasty

edited by Jun-Dong Chang

submission deadline 18 Jan 2026 | 1 articles | Viewed by 919 | Submission Open

Keywords: hip arthroplasty; knee arthroplasty; joint replacement; revision surgery; orthopedic implants; robotic surgery; peri-operative care; functional outcomes; complication management; orthopedic innovation

(This special issue belongs to the Section Orthopedics)

New Technologies in Neurosurgery: An Insight into the Future

edited by Ismail Zaed

submission deadline 19 Jan 2026 | 1 articles | Viewed by 1601 | Submission Open

Keywords: neurosurgery; training; technology; augmented reality; virtual reality; robot

(This special issue belongs to the Section Clinical Neurology)

Rheumatoid Arthritis: Clinical Updates on Diagnosis and Treatment

edited by

Shunsuke Mori

submission deadline 20 Jan 2026 | 12 articles | Viewed by 37403 | Submission Open

Keywords: rheumatoid arthritis; disease-modifying antirheumatic drugs (DMARDs); biological therapies; Janus kinase inhibitors (JAK inhibitors); treatment strategies; joint destruction; comorbidity; drug safety

(This special issue belongs to the Section Immunology & Rheumatology)

Cataract and Refractive Surgery, and Intraocular Lens (IOL) Implantation: Recent Advances and Perspectives

edited by Ehud I. Assia

submission deadline 20 Jan 2026 | 14 articles | Viewed by 18273 | Submission Open

Keywords: premium IOLs (multifocal and toric); IOL power calculation; biometry and imaging; complications and management; laser vision correction; phakic IOLs; femtosecond-laser-assisted cataract surgery; AI (artificial intelligence) and cataract/refractive surgery; accommodative lenses

(This special issue belongs to the Section Ophthalmology)

Chronic Complications of Type 2 Diabetes: Prevalence, Prevention, and Management

edited by

Ilias Migdalis

submission deadline 20 Jan 2026 | 9 articles | Viewed by 17849 | Submission Open

Keywords: pathogenesis of diabetic complications; epidemiology of diabetic complications; diabetic retinopathy; diabetic chronic kidney disease; diabetes neuropathies; coronary heart disease; peripheral vascular disease; hypertension and dyslipidemia in diabetes

(This special issue belongs to the Section Endocrinology & Metabolism)

Hernia Surgery and Postoperative Management

edited by Jacob Rosenberg

submission deadline 20 Jan 2026 | 5 articles | Viewed by 15218 | Submission Open

Keywords: hernia surgery; hernia repair; abdominal hernia; preoperative; intraoperative; postoperative; management; complications

(This special issue belongs to the Section General Surgery)

New Insights into Infectious Skin and Mucosal Diseases

edited by

Giulia Ciccarese

Sebastiano Recalcati

and Astrid Herzum

submission deadline 20 Jan 2026 | 6 articles | Viewed by 14944 | Submission Open

Keywords: exanthem; latent viruses; infectious diseases; skin eruptions; sexually transmitted infections

(This special issue belongs to the Section Dermatology)

Advanced Strategies and Innovations to Enhance Outcomes in Cardiac Ablation

edited by

Nikolaos K. Fragakis

and

Paschalis Karakasis

submission deadline 20 Jan 2026 | 4 articles | Viewed by 11943 | Submission Open

Keywords: arrhythmias; cardiac ablation; catheter technology; imaging; anticoagulation optimization; post-procedure care

(This special issue belongs to the Section Cardiology)

POTS, ME/CFS and Long COVID: Recent Advances and Future Direction

edited by Svetlana Blitshteyn

submission deadline 20 Jan 2026 | 2 articles | Viewed by 11903 | Submission Open

Keywords: POTS; ME/CFS; long COVID; dysautonomia; orthostatic intolerance; autoimmunity

(This special issue belongs to the Section Immunology & Rheumatology)

Multidisciplinarity in Thoraco-Pulmonary Diseases: Every Generation Needs a New Revolution. Insights from the XXII SIET National Meeting

edited by Federico Raveglia,

Carmelina C. Zirafa

and

Mohsen Ibrahim

submission deadline 20 Jan 2026 | 7 articles | Viewed by 11574 | Submission Open

Keywords: lung cancer; interventional endoscopy; upper airway reconstruction; robotic diagnosis; robotic surgery

(This special issue belongs to the Section Respiratory Medicine)

Oral Health in Children: Clinical Management

edited by

Yolanda Martinez Beneyto

submission deadline 20 Jan 2026 | 7 articles | Viewed by 9322 | Submission Open

Keywords: pediatric oral health; early childhood caries; preventive strategies; comprehensive clinical approach; early detection; oral care; minimal intervention dentistry

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Displaying special issue 401-450 on page 9 of 31.

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