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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in Neurological Rehabilitation: Innovations and Clinical Insights

edited by

Anna Berardi

submission deadline 20 Feb 2026 | 2 articles | Viewed by 1802 | Submission Open

Keywords: rehabilitation; neurology; assessment; occupational therapy; disability; inclusion

(This special issue belongs to the Section Clinical Neurology)

Clinical Updates in Stem Cell Transplants

edited by Daniele Avenoso and Michele Malagola

submission deadline 20 Feb 2026 | 3 articles | Viewed by 1792 | Submission Open

Keywords: AML; CML; lymphoma; allo-HSCT; GVHD; MDS; AA

(This special issue belongs to the Section Hematology)

Integrating Psychological Science into Chronic Pain Management: Emerging Approaches and Insights

edited by Scott G. Ravyts and Margot De Kooning

submission deadline 20 Feb 2026 | 2 articles | Viewed by 1681 | Submission Open

Keywords: chronic primary pain; nociplastic pain; coping strategies; depression; anxiety; trauma

(This special issue belongs to the Section Mental Health)

Advanced Hysteroscopic Technology for Gynecological Disease

edited by

Guglielmo Stabile

Luigi Nappi

and

Felice Sorrentino

submission deadline 20 Feb 2026 | 3 articles | Viewed by 1587 | Submission Open

Keywords: hysteroscopy; new technology; therapy; mini-invasive approach; laser; diagnosis; outcomes

(This special issue belongs to the Section Obstetrics & Gynecology)

Management of Endometriosis: Evidence-Based Updated by Collective Clinical Experience and New Perspectives from Research

edited by

Philippe R. Koninckx

, Arnaud Wattiez and

Sun-Wei Guo

submission deadline 20 Feb 2026 | 2 articles | Viewed by 1565 | Submission Open

Keywords: endometriosis; guidelines; surgery; medical treatment; training; heuristics

(This special issue belongs to the Section Clinical Guidelines)

Clinical Updates and Personalized Medicine in Hepatocellular Carcinoma and Liver Transplantation

edited by Adriano Pellicelli

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1369 | Submission Open

Keywords: hepatocellular carcinoma; transarterial chemoembolization (TACE); transarterial radioembolization (TARE); liver transplant; immune checkpoint inhibitors (ICI); tyrosine kinase inhibitor; liver function assessment; Child-Pugh score; bridging to liver transplantation; immuno escape

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Current Trends and Future Challenges in Percutaneous Coronary Intervention

edited by Deniz Mutlu

submission deadline 20 Feb 2026 | 3 articles | Viewed by 1365 | Submission Open

Keywords: PCI; IVUS; OCT; FFR; physiology; CT-guided PCI; complex PCI; CTO; bifurcation; coronary complications; mechanical circulatory support

(This special issue belongs to the Section Cardiovascular Medicine)

Innovations in Personalized Therapy and Clinical Outcomes for Myopia and Ocular Disorders

edited by

Clara Martinez-Perez

submission deadline 20 Feb 2026 | 2 articles | Viewed by 1360 | Submission Open

Keywords: myopia; refractive errors; visual development; childhood eye disorders; vision screening; diagnostic tools in optometry; vision-related quality of life; therapeutic strategies in optometry; artificial intelligence; public health; eye care innovation; multidisciplinary vision science

(This special issue belongs to the Section Ophthalmology)

Clinical Insights and Emerging Strategies in Chronic Pain Management

edited by

Cheol Lee

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1335 | Submission Open

Keywords: chronic pain; neuropathic pain; multimodal pain management; digital health; real-world evidence; interdiscipli-nary care

(This special issue belongs to the Section Anesthesiology)

Breast Cancer: Symptoms, Types, Causes & Treatment

edited by Min-Jeong Cho and Sara Myers

submission deadline 20 Feb 2026 | 2 articles | Viewed by 1249 | Submission Open

Keywords: ductal carcinoma in situ (DCIS); breast cancer; breast cancer prevention; minimally invasive surgery; innovative imaging technologies

(This special issue belongs to the Section Obstetrics & Gynecology)

Cardio-Oncology: Clinical Advances in Cardiotoxicity Detection, Imaging and Therapeutic Strategies

edited by

Nicola Maurea

and

Alfredo Mauriello

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1129 | Submission Open

Keywords: cardio-oncology; cardiovascular toxicity; targeted therapies; echocardiography; PET/CT

(This special issue belongs to the Section Cardiology)

Deep Vein Thrombosis and Pulmonary Embolism: Clinical Treatment and Management—Second Edition

edited by

Pablo Demelo-Rodríguez

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1096 | Submission Open

Keywords: pulmonary embolism; thrombophilia; deep vein thrombosis; venous thromboembolism; anticoagulation therapy; thrombectomy; bleeding; cancer-associated thrombosis

(This special issue belongs to the Section Hematology)

Current Opinion of Reconstructive and Aesthetic Breast Surgery

edited by

Lukas Prantl

, Konstantin Frank and Vanessa Brébant

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1038 | Submission Open

Keywords: reconstructive breast surgery; lipofilling; microsurgery; aesthetic breast surgery; PROM; digital anthropometry; autologous fat transfer; ADM; synthetic mesh; BIA-ALCL; BII

(This special issue belongs to the Section General Surgery)

Breakthroughs in Spine Biomechanics: Diagnostics and Treatment Approaches for Body Posture, Scoliosis and Chronic Back Pain

edited by

Maciej Rachwał

and

Joanna Baran

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1021 | Submission Open

Keywords: spinal biomechanics; spinal pathologies; idiopathic scoliosis; postural abnormalities; spinal pain syndromes; spinal deformities; chronic spinal pain

(This special issue belongs to the Section Orthopedics)

Updates on Neurosurgical Techniques, Management, and Outcomes for Intracranial Hemorrhages

edited by Bruno Splavski

submission deadline 20 Feb 2026 | 1 articles | Viewed by 992 | Submission Open

Keywords: minimally invasive neurosurgery; neuro-intervention endovascular techniques; intracranial hemorrhage; stroke; hemorrhagic; ischemic; neurosurgical decision-making; long-term outcomes in neurosurgery

(This special issue belongs to the Section Clinical Neurology)

Hepatobiliary Surgery: State of the Art and Future Perspectives

edited by

Teresa Perra

and

Alberto Porcu

submission deadline 20 Feb 2026 | 1 articles | Viewed by 948 | Submission Open

Keywords: hepatobiliary surgery; cholangiocarcinoma; hepatocellular carcinoma; liver metastases; benign liver lesions

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Clinical Translation of Technological Innovations in Diabetes Therapeutics

edited by

Nowreen Haq

submission deadline 20 Feb 2026 | 1 articles | Viewed by 940 | Submission Open

Keywords: diabetes management; remote patient monitoring (RPM); artificial intelligence (AI); machine learning (ML); wearable sensors; point-of-care diagnostics; centrifugal microfluidics; glucose monitoring

(This special issue belongs to the Section Endocrinology & Metabolism)

Advances in the Field of Cutaneous Malignancies: Background and Clinical Management

edited by

and

submission deadline 20 Feb 2026 | 1 articles | Viewed by 914 | Submission Open

Keywords: dermatology; skin cancer; diagnosis; melanoma; basal cell carcinoma; squamous cell carcinoma; imaging; artificial intelligence; dermoscopy; treatment

(This special issue belongs to the Section Dermatology)

Orthopedic Trauma: Diagnosis, Treatment and Rehabilitation

edited by

Emmanouil Liodakis

submission deadline 20 Feb 2026 | 1 articles | Viewed by 871 | Submission Open

Keywords: orthopedic trauma; fragility fractures; biomechanics; bone defect; pelvic ring; acetabular fractures; amputation; re-habilitation

(This special issue belongs to the Section Orthopedics)

Cancer Immunotherapy: Recent Advances and Clinical Challenges

edited by

Antonello Veccia

submission deadline 20 Feb 2026 | 1 articles | Viewed by 869 | Submission Open

Keywords: immune checkpoint inhibitors; solid tumors; early-stage disease; metastatic disease; prognostic factors; biomarkers; resistance mechanisms

(This special issue belongs to the Section Oncology)

Advances and Updates in Migraine

edited by

Hartmut Göbel

and Carl H. Göbel

submission deadline 20 Feb 2026 | 1 articles | Viewed by 850 | Submission Open

Keywords: migraine; chronic migraine; headache disorders; CGRP antibodies; gepants; ditans; triptans; precision medicine; neuromodulation; comorbidities; disability burden; pediatric migraine; ICHD-3 classification; neurotransmitters; preventive therapy; translational headache research

(This special issue belongs to the Section Clinical Neurology)

Advances in Maternal–Fetal Medicine

edited by

C. Andrew Combs

submission deadline 20 Feb 2026 | 1 articles | Viewed by 826 | Submission Open

Keywords: maternal– fetal medicine; obstetric ultrasound; preterm birth; preeclampsia; pregnancy complications; artificial intelligence

(This special issue belongs to the Section Obstetrics & Gynecology)

Clinical Applications of Cardiac Imaging: 2nd Edition

edited by Maria Concetta Pastore

submission deadline 20 Feb 2026 | 2 articles | Viewed by 825 | Submission Open

Keywords: cardiac imaging; echocardiography; magnetic resonance imaging; computed tomography; nuclear imaging; heart failure; valvular heart disease; congenital heart disease

(This special issue belongs to the Section Cardiology)

Current Opinion in Dental Implant Surgery and Peri-Implant Disease

edited by

Giorgio Lombardo

and Giovanni Corrocher

submission deadline 20 Feb 2026 | 1 articles | Viewed by 817 | Submission Open

Keywords: dental implant surgery; dental implantology; peri-implant disease; oral surgery; dental implantology

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Age-Related Macular Degeneration: Challenges and Opportunities

edited by Deepayan Kar

submission deadline 20 Feb 2026 | 1 articles | Viewed by 800 | Submission Open

Keywords: age-related macular degeneration; imaging biomarkers; visual function testing; optical coherence tomography; anti-VEGF; complement; artificial intelligence

(This special issue belongs to the Section Ophthalmology)

Novel Developments in Digestive Endoscopy

edited by

Arnaldo Amato

submission deadline 20 Feb 2026 | 1 articles | Viewed by 776 | Submission Open

Keywords: endoscopy for IBD; AI in endoscopy; therapeutic endoscopy; EUS; interventional EUS; AI in digestive endoscopy; quality in endoscopy

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Diagnosis and Treatment of Gastrointestinal Malignancies

edited by

Carmelo Laface

and Gianmauro Numico

submission deadline 20 Feb 2026 | 1 articles | Viewed by 745 | Submission Open

Keywords: gastrointestinal cancers; immunotherapy; targeted therapy; chemotherapy; microsatellite instability; driver mutations

(This special issue belongs to the Section Oncology)

Treatment and Long-Term Outcome of Fracture

edited by

Corrado Ciatti

Edoardo Bori

and Fabrizio Quattrini

submission deadline 20 Feb 2026 | 1 articles | Viewed by 713 | Submission Open

Keywords: traumatology; osteosynthesis; plating; nailing; osteosynthesis devices; surgical technique; approach

(This special issue belongs to the Section Orthopedics)

Rising Star: Advanced Physical Therapy and Expansion

edited by

Hyolyun Roh

submission deadline 20 Feb 2026 | 1 articles | Viewed by 691 | Submission Open

Keywords: physical therapy; digital therapeutic technology; geriatric diseases; pediatric; psychology of physical therapies; clinical approach

(This special issue belongs to the Section Clinical Rehabilitation)

New Insights into Orthodontic Treatment

edited by Federico Brugnami and Simonetta Meuli

submission deadline 20 Feb 2026 | 1 articles | Viewed by 671 | Submission Open

Keywords: digital orthodontics; clear aligners; artificial intelligence; digital superimpositions; cone beam computed tomography; growing patients; periodontal patients; maxillofacial surgery; long-term stability; prediction of orthodontic movements

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Clinical Update on Cardiac Rehabilitation

edited by

Bruno Bordoni

submission deadline 20 Feb 2026 | Viewed by 618 | Submission Open

Keywords: cardiac rehabilitation; cardiovascular disease; physiotherapy; interprofessional intervention; exercise training; nutritional counseling; psychosocial support; secondary prevention; rehabilitation modalities; rehabilitation tools

(This special issue belongs to the Section Clinical Rehabilitation)

Current Challenges and Innovations in Emergency Medicine: From Prehospital Care to Critical Decision-Making in the Emergency Department

edited by

Efstratios Karagiannidis

, Barbara P. Fyntanidou and

Aikaterini Apostolopoulou

submission deadline 20 Feb 2026 | 1 articles | Viewed by 606 | Submission Open

Keywords: emergency medicine; prehospital care; triage strategies; acute care; point-of-care diagnostics; artificial intelligence; telemedicine; emergency department; patient flow; healthcare systems; burnout in emergency care

(This special issue belongs to the Section Emergency Medicine)

New Insights in Cognitive Aging and Mild Cognitive Impairment

edited by

Irene Fernández

and

Laura Galiana

submission deadline 20 Feb 2026 | 1 articles | Viewed by 510 | Submission Open

Keywords: cognitive aging; mild cognitive impairment; normative aging; neuropsychological assessment; diagnosis; gerontology; prevention; intervention; multidisciplinary approach; measurement

(This special issue belongs to the Section Geriatric Medicine)

Novel Research in Pediatric Dentistry: 2nd Edition

edited by Christian Hirsch and

Katrin Bekes

submission deadline 20 Feb 2026 | 1 articles | Viewed by 459 | Submission Open

Keywords: early childhood caries; primary teeth; caries prevention; caries treatment; behavioral management; molar incisor hypomineralization; dental trauma; sedation; oral health-related quality of life

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

State of the Art in Interventional Cardiology

edited by Antonios Karanasos

submission deadline 20 Feb 2026 | Viewed by 457 | Submission Open

Keywords: interventional cardiology; intravascular imaging; structural interventions; TAVI; vascular access; percutaneous coronary intervention; coronary stenting; cardiovascular diseases

(This special issue belongs to the Section Cardiology)

Cardiac Anesthesia: Current Research and Future Prospects

edited by

Fabio Sangalli

and Lorenzo Stephan Cesare Grazioli

submission deadline 20 Feb 2026 | Viewed by 366 | Submission Open

Keywords: cardiac anesthesia; cardiac surgery; echocardiography; interventional cardiology; anesthesia; cardiology

(This special issue belongs to the Section Anesthesiology)

Current and Emerging Treatment Options in Atrial Fibrillation: 2nd Edition

edited by

Marco Valerio Mariani

submission deadline 20 Feb 2026 | Viewed by 327 | Submission Open

Keywords: atrial fibrillation; left atrial appendage closure; ablation techniques; personalized medicine in AF treatment; cardioversion methods

(This special issue belongs to the Section Cardiology)

Diagnosis and Treatment of Cardiovascular Diseases in the Elderly

edited by

Carmelo Massimiliano Rao

submission deadline 20 Feb 2026 | 1 articles | Viewed by 325 | Submission Open

Keywords: cardiovascular diseases; elderly population; diagnosis and management; age-related pathophysiology; frailty and cognitive impairment

(This special issue belongs to the Section Geriatric Medicine)

Disease Modifying Activity in Psoriasis and Atopic Dermatitis

edited by

Elena Pezzolo

and

Paolo Gisondi

submission deadline 20 Feb 2026 | Viewed by 291 | Submission Open

Keywords: atopic dermatitis; biologics; psoriasis; disease-modifying treatment; small molecules; type 2 inflammation

(This special issue belongs to the Section Dermatology)

Novel Insights for Imaging and Therapy in Maternal and Fetal Medicine

edited by Xin Kang

submission deadline 20 Feb 2026 | Viewed by 259 | Submission Open

Keywords: prenatal imaging; prenatal diagnosis; fetal virtual autopsy; preeclampsia; macrosomia; preterm birth; pelvic floor

(This special issue belongs to the Section Obstetrics & Gynecology)

Endocrine Disorders in Children: 2nd Edition

edited by

Juan Pedro López-Siguero

submission deadline 20 Feb 2026 | Viewed by 179 | Submission Open

Keywords: endocrinology; pediatrics; hormones; genetics; growth; nutrition; development ; adolescence ; prevention

(This special issue belongs to the Section Clinical Pediatrics)

Minimally Invasive Surgery for Gastrointestinal Disorder

edited by

Amosy Ephreim M'Koma

submission deadline 20 Feb 2026 | 1 articles | Viewed by 172 | Submission Open

Keywords: minimally invasive surgery; gastrointestinal disorder; laparoscopy; robotic surgery; colorectal surgery; gastric surgery; endoscopic technique; oncological outcomes; surgical innovation

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Hypercholesterolemia: Update on Treatment Approaches and Outcomes

edited by

Massimiliano Ruscica

and Lucia Barbieri

submission deadline 20 Feb 2026 | Viewed by 162 | Submission Open

Keywords: hypercholesterolemia; dyslipidemia; atherosclerosis; cardiovascular risk; LDL; HDL; lipoprotein(a)

(This special issue belongs to the Section Cardiovascular Medicine)

Maxillofacial Surgery in the Modern Era: Surgical Advances and Clinical Innovation

edited by

Jeremie Oliver Piña

submission deadline 20 Feb 2026 | Viewed by 162 | Submission Open

Keywords: maxillofacial surgery; oral surgery; craniofacial surgery; plastic surgery; bone

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Recent Advances and Future Perspectives on Spinal Surgeries

edited by

Sung-kyu Kim

submission deadline 20 Feb 2026 | Viewed by 157 | Submission Open

Keywords: minimally invasive spine procedures; robotic-assisted spine surgery; image-guided navigation; spinal implants and biomaterials; artificial intelligence in spinal care; regenerative spine therapies; clinical outcomes in spine surgery; future trends in spinal interventions

(This special issue belongs to the Section Orthopedics)

Advances in the Diagnosis and Management of Atherosclerosis

edited by

Adrian Covic

and

Cristian Stătescu

submission deadline 20 Feb 2026 | Viewed by 155 | Submission Open

Keywords: atherosclerosis; cardiovascular disease; coronary artery disease; endothelial function; acute coronary syndromes

(This special issue belongs to the Section Cardiology)

Advances and Innovations in Radiology: From Contrast-Enhanced Mammography to Artificial Intelligence and Beyond

edited by

Luca Nicosia

submission deadline 20 Feb 2026 | Viewed by 151 | Submission Open

Keywords: contrast-enhanced mammography (CEM); artificial intelligence; radiomics; diagnostic imaging innovations; inter-ventional radiology

(This special issue belongs to the Section Nuclear Medicine & Radiology)

Progress and Innovation in the Clinical Management of Psychosis

edited by

Valerio Ricci

submission deadline 20 Feb 2026 | Viewed by 150 | Submission Open

Keywords: psychosis; schizophrenia; clinical interventions; neurobiological mechanisms; early intervention

(This special issue belongs to the Section Mental Health)

Innovations and Challenges in the Burden and Rehabilitation of Musculoskeletal Disorders

edited by

Carla Sílvia Fernandes

and

Marta Campos Ferreira

submission deadline 20 Feb 2026 | Viewed by 142 | Submission Open

Keywords: musculoskeletal diseases; rehabilitation; physical therapy modalities; telemedicine; mobile applications; health information technology; patient-centered care; quality of life; health care innovation

(This special issue belongs to the Section Clinical Rehabilitation)

Myocarditis and Pericarditis: Clinical Advances and Current Challenges

edited by

Ankit Agrawal

and

Tom Kai Ming Wang

submission deadline 20 Feb 2026 | Viewed by 138 | Submission Open

Keywords: pericarditis; myocarditis; pericardial effusion; cardiac tamponade; interleukin-1 inhibitors; pericardium

(This special issue belongs to the Section Cardiovascular Medicine)

Displaying special issue 601-650 on page 13 of 32.