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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Clinical Research on Pulmonary Hypertension and Its Complications
edited by Gabor G. Kovacs and
submission deadline 20 Apr 2026 | Viewed by 65 | Submission Open
Keywords: pulmonary hypertension; PH; pulmonary arterial pressure; different diagnostic; therapeutic challenges
(This special issue belongs to the Section Respiratory Medicine)
Innovations in Surgical and Medical Approaches of Urologic Oncology
edited by
submission deadline 20 Apr 2026 | Viewed by 60 | Submission Open
Keywords: urologic oncology; robotic surgery; immunotherapy; targeted therapy; image-guided techniques; personalized medicine; minimally invasive surgery; focal therapy
(This special issue belongs to the Section Nephrology & Urology)
Spinal Cord Injury in Elderly People: Prevention of Complications
edited by Vaidyanathan Subramanian
submission deadline 20 Apr 2026 | Viewed by 60 | Submission Open
Keywords: spinal cord injury; demography; morbidities; complications; spinal injuries; patients; family members; caregivers; general practitioners; discharge; elderly
(This special issue belongs to the Section Geriatric Medicine)
Clinical Cardiac Rehabilitation: Integrating Multidimensional Approaches for Enhanced Cardiovascular Health
edited by
submission deadline 20 Apr 2026 | Viewed by 59 | Submission Open
Keywords: cardiac rehabilitation; multidimensional approach; integrating approach; cardiovascular health; primary and secondary prevention
(This special issue belongs to the Section Clinical Rehabilitation)
New Challenges and Perspectives in Surgical Treatment of Spinal Deformity
edited by Jung-Hee Lee
submission deadline 20 Apr 2026 | Viewed by 53 | Submission Open
Keywords: adult spinal deformity; decompensation; kyphosis; lateral lumbar interbody fusion; orthopedic surgery; osteotomy; proximal junctional kyphosis; rod fracture
(This special issue belongs to the Section Orthopedics)
Aiming for Early Detection and Prevention of Pulmonary Diseases submission deadline 20 Apr 2026 | Viewed by 41 | Submission Open
Keywords: early diagnosis; prevention strategies; respiratory diseases; artificial intelligence; asthma; chronic obstructive pulmonary disease (COPD); interstitial lung disease; sleep-disordered breathing
(This special issue belongs to the Section Respiratory Medicine)
What Part Do Circulating Tumor Cells Play in Cancers? submission deadline 20 Apr 2026 | Viewed by 29 | Submission Open
Keywords: circulating tumor cells (CTCs); circulating cancer stem cells (cCSCs); liquid biopsy; therapy monitoring; metastasis; cancer progression
(This special issue belongs to the Section Oncology)
Genitourinary Tumors and Radiation Therapy: Current Advances and Future Directions
edited by Shalini Moningi
submission deadline 20 Apr 2026 | Viewed by 23 | Submission Open
Keywords: cancer; prostate cancer; bladder cancer; kidney cancer; radiation therapy
(This special issue belongs to the Section Nuclear Medicine & Radiology)
Clinical Management of Knee Arthroplasty
edited by
submission deadline 21 Apr 2026 | 1 articles | Viewed by 783 | Submission Open
Keywords: knee surgery; knee arthroplasty; knee joint replacement; osteoarthritis; knee arthritis
(This special issue belongs to the Section Orthopedics)
Controversies in Hidradenitis Suppurativa: Bridging Gaps in Science and Practice
edited by Hadar Lev-Tov and Tammy González
submission deadline 21 Apr 2026 | Viewed by 103 | Submission Open
Keywords: hidradenitis suppurativa (HS); inflammatory skin disorder; controversies; treatment strategies; science and practice
(This special issue belongs to the Section Dermatology)
Paediatric Anaesthesia: Clinical Updates and Perspectives
edited by Peter Marhofer, Philipp Opfermann and Markus Zadrazil
submission deadline 24 Apr 2026 | 7 articles | Viewed by 9250 | Submission Open
Keywords: pediatric anesthesia; anesthesia; conduction; ultrasonography; conscious sedation; deep sedation; drug-related side effects and adverse reactions; neurotoxicity syndromes
(This special issue belongs to the Section Anesthesiology)
Challenges and Advances in Geriatrics and Gerontology
edited by Elisa Fabbri
submission deadline 24 Apr 2026 | 5 articles | Viewed by 2745 | Submission Open
Keywords: aging; geriatric medicine; frailty; multimorbidity; sarcopenia; cognition; personalized-care; healthy longevity; decision making-management; prevention; artificial intelligence
(This special issue belongs to the Section Geriatric Medicine)
Advances in Spine Surgery: Current Innovations and Future Directions
edited by and Jesús Burgos
submission deadline 24 Apr 2026 | Viewed by 131 | Submission Open
Keywords: spine; clinical studies; robotics; minimally invasive; complications; patient-reported outcomes; reviews
(This special issue belongs to the Section Orthopedics)
Innovations and Challenges in Clinical Toxicology and Therapeutic Drug Monitoring
edited by Zhicheng Jin
submission deadline 25 Apr 2026 | 2 articles | Viewed by 20768 | Submission Open
Keywords: toxicology screen; therapeutic drug monitoring; mass spectrometry; immunoassays; pain management; opioids
(This special issue belongs to the Section Pharmacology)
General Anesthesia: Recent Developments and Emerging Trends
edited by Basavana Goudra
submission deadline 25 Apr 2026 | 3 articles | Viewed by 16527 | Submission Open
Keywords: general anesthesia; recent advances; drug development; memory and awareness; brain monitoring; sugammadex; tegileridine
(This special issue belongs to the Section Anesthesiology)
Clinical Management of Oral Healthcare in Diverse Patient Populations: Second Edition submission deadline 25 Apr 2026 | 10 articles | Viewed by 15247 | Submission Open
Keywords: special needs patients; oral healthcare; pediatric dentistry; dental hygiene; oral pathology; orthodontics; periodontics
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Clinical Perspectives on Surgical Management of Knee Injuries
edited by Min Jung
submission deadline 25 Apr 2026 | 6 articles | Viewed by 11027 | Submission Open
Keywords: osteoarthritis; meniscal repair; ligament reconstruction; cartilage restoration; knee surgery
(This special issue belongs to the Section Orthopedics)
Clinical Insights into Pulmonary Hypertension
edited by Simon Schneider
submission deadline 25 Apr 2026 | 5 articles | Viewed by 10354 | Submission Open
Keywords: pulmonary hypertension; pulmonary vascular disease (PVD); pulmonary arterial hypertension (PAH); chronic thromboembolic pulmonary hypertension (CTEPH); interstitial lung disease; chronic obstructive pulmonary disease (COPD); chronic pulmonary fibrosis; emphysema; respiratory disease; physiology; diagnosis; treatment; rehabilitation; altitude research
(This special issue belongs to the Section Respiratory Medicine)
Clinical Advances in Abdominal Surgery
edited by and César P. Ramírez-Plaza
submission deadline 25 Apr 2026 | 5 articles | Viewed by 6735 | Submission Open
Keywords: abdominal surgery; oncologic surgery; minimal invasive techniques; HIPEC; PIPAC; peritoneal carcinomatosis; liver metastasis
(This special issue belongs to the Section General Surgery)
Assessment and Treatment of Trauma Patients
edited by
submission deadline 25 Apr 2026 | 3 articles | Viewed by 6637 | Submission Open
Keywords: trauma surgery; prehospital detection of trauma; assessment of trauma; trauma scale; trauma evaluation; trauma surgery
(This special issue belongs to the Section Emergency Medicine)
Innovations in Perioperative Anesthesia and Intensive Care
edited by and Ileana Lulic
submission deadline 25 Apr 2026 | 4 articles | Viewed by 5739 | Submission Open
Keywords: perioperative anesthesia; intensive care; artificial intelligence in anesthesia; precision medicine in perioperative care; hemodynamic monitoring; multimodal analgesia; opioid-free anesthesia; ventilation strategies in ICU and surgery; neuromonitoring and sedation; perioperative resuscitation and ECMO
(This special issue belongs to the Section Intensive Care)
Advances in Structural Heart Diseases
edited by , and Erwan Donal
submission deadline 25 Apr 2026 | 2 articles | Viewed by 5387 | Submission Open
Keywords: valvular heart diseases; transcatheter interventions; TEER; LAA closure; ASD closure; interventional echocardiography; multimodality cardiac imaging; three-dimensional echocardiography
(This special issue belongs to the Section Cardiovascular Medicine)
Hand Surgery: Latest Advances and Prospects
edited by and Lorenzo Rocchi
submission deadline 25 Apr 2026 | 4 articles | Viewed by 5355 | Submission Open
Keywords: hand surgery; musculoskeletal and nerve disorders; innovative surgical procedures; minimally invasive techniques; rehabilitation strategies; robotic surgery
(This special issue belongs to the Section Orthopedics)
Experience and New Application in Otolaryngology and Maxillofacial Surgery
edited by Riccardo Nocini
submission deadline 25 Apr 2026 | 1 articles | Viewed by 3919 | Submission Open
Keywords: new surgical techniques; robotics; endoscopy; revascularized free flaps; innovation; 3D surgical planning.
(This special issue belongs to the Section Otolaryngology)
Oral and Maxillofacial Surgery: Current Advances and Future Directions
edited by Niedzielska Iwona
submission deadline 25 Apr 2026 | 1 articles | Viewed by 3398 | Submission Open
Keywords: oral and maxillofacial surgery; reconstructive surgery; periodontitis; dental implants; maxillofacial deformities
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Advances in the Diagnosis and Treatment of Skin Cancer submission deadline 25 Apr 2026 | 2 articles | Viewed by 2723 | Submission Open
Keywords: skin cancer; melanoma; keratinocyte carcinoma; basal cell carcinoma; squamous cell carcinoma; biomarkers; immuno-therapy; prognosis
(This special issue belongs to the Section Oncology)
Catheter Ablation of Atrial Fibrillation: Current Progress and New Challenges
edited by Sorin Stefan Popescu, Roland Richard Tilz and Karl-Heinz Kuck
submission deadline 25 Apr 2026 | 2 articles | Viewed by 2490 | Submission Open
Keywords: atrial fibrillation; novel technologies; pulmonary vein isolation; same-day discharge; pulsed field ablation; cryo-ablation; radiofrequency; safety; efficacy; sustainability
(This special issue belongs to the Section Cardiology)
Interventional Cardiology: Recent Advances and Future Perspectives
edited by Cristina Aurigemma and Luigi Cappannoli
submission deadline 25 Apr 2026 | 3 articles | Viewed by 2224 | Submission Open
Keywords: interventional cardiology; percutaneous coronary intervention (PCI); transcatheter aortic valve implantation (TAVI); structural heart disease; coronary artery disease; imaging and artificial intelligence; antithrombotic therapy; future technologies in cardiology; personalized cardiovascular care; minimally invasive interventions
(This special issue belongs to the Section Cardiology)
Current Trends and Future Prospects in Autoantibodies in Liver Diseases
edited by Takashi Himoto
submission deadline 25 Apr 2026 | 1 articles | Viewed by 2131 | Submission Open
Keywords: liver-specific autoantibodies; non-organ-specific autoantibodies; autoimmune liver disease; diagnosis; disease activity; treatment outcome; prognosis; virus-induced autoimmunity; drug-induced autoimmunity
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Endoscopic Diagnosis and Treatments of Gastrointestinal Diseases
edited by Madalina Ilie and Mihai Ciocîrlan
submission deadline 25 Apr 2026 | 3 articles | Viewed by 2083 | Submission Open
Keywords: esogastric lesions; pancreatic diseases; colorectal lesions; hepatobiliary diseases; optical endoscopy; endoscopic ultrasound; upper and lower endoscopy; endoscopic retrograde cholangiopancreatography
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Endometriosis and Endometrial Cancer: Challenge and Clinical Management
edited by , Tomasz Kluz and Bernhard Krämer
submission deadline 25 Apr 2026 | 1 articles | Viewed by 2064 | Submission Open
Keywords: endometriosis; endometrial cancer; non-invasive diagnosis; molecular profiling; surgical techniques; medical treatment; alternative therapies
(This special issue belongs to the Section Obstetrics & Gynecology)
Cardiac Magnetic Resonance Imaging: Current Techniques and Future Directions
edited by Ioannis Botis and
submission deadline 25 Apr 2026 | 1 articles | Viewed by 1665 | Submission Open
Keywords: cardiac magnetic resonance imaging; cardiovascular magnetic resonance; cardiac imaging; multimodality imaging; parametric mapping; late gadolinium enhancement; myocardial perfusion; myocardial viability; cardiomyopathies; heart failure
(This special issue belongs to the Section Cardiology)
Advances in Primary Sclerosing Cholangitis: Pathogenesis, Diagnosis and Emerging Therapies
edited by Konstantinos H. Katsanos and
submission deadline 25 Apr 2026 | 2 articles | Viewed by 1554 | Submission Open
Keywords: cholangiocarcinoma; primary sclerosing cholangitis; cholestatic; inflammatory bowel disease; liver
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
New Advances in Procedures for the Diagnosis and Treatment of Cardiovascular Disease submission deadline 25 Apr 2026 | Viewed by 1379 | Submission Open
Keywords: cardiovascular disease; diagnostic procedures; therapeutic advancements; minimally invasive interventions; precision medicine; imaging technologies; catheter-based treatments; translational research; interventional cardiology; clinical innovations
(This special issue belongs to the Section Cardiovascular Medicine)
General Surgical Oncology: Evolving Paradigms and Contemporary Challenges submission deadline 25 Apr 2026 | 1 articles | Viewed by 1235 | Submission Open
Keywords: surgical oncology; minimally invasive surgery; robotic surgery; multidisciplinary cancer care; artificial intelligence in surgery; perioperative management; precision oncology; complex tumor resection; integrated surgical therapies; oncologic surgery innovation
(This special issue belongs to the Section Oncology)
Urologic Neoplasms: Recent Advances and Future Perspectives
edited by
submission deadline 25 Apr 2026 | 1 articles | Viewed by 848 | Submission Open
Keywords: robotic surgery; laparoscopic surgery; immunotherapy; chemotherapy; radiotherapy; prostate cancer; renal cancer; bladder cancer; upper urinary tract neoplasm; testicular cancer; penile cancer
(This special issue belongs to the Section Oncology)
Recent Advances in Pulmonary Embolism and Thrombosis: 2nd Edition
edited by and Elena Campello
submission deadline 25 Apr 2026 | 1 articles | Viewed by 635 | Submission Open
Keywords: pulmonary embolism; embolism and thrombosis; thrombus aspiration for pulmonary embolism; deep vein thrombosis; venous thromboembolism
(This special issue belongs to the Section Respiratory Medicine)
New Advances in Cleft Lip and Palate and Facial Plastic Surgery
edited by , Wolfgang Zemann and Rainer Lutz
submission deadline 25 Apr 2026 | 1 articles | Viewed by 452 | Submission Open
Keywords: cleft lip repair; rhinoplasty; secondary rhinoplasty; cleft rhinoplasty; facial plastic surgery; nasolabial area; upper lid surgery
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
Robot-Assisted Surgery: Current Trends and Future Directions
edited by , Claudio Bisegna and Michele Morelli
submission deadline 25 Apr 2026 | 1 articles | Viewed by 414 | Submission Open
Keywords: robotic surgery; minimally invasive surgery; urology; artificial intelligence; augmented reality; public health; innovation; laparoscopic surgery; surgical platforms; surgical outcomes
(This special issue belongs to the Section General Surgery)
Recent Developments in Reproductive Endocrinology
edited by Birute Žilaitiené and Jonas Čeponis
submission deadline 25 Apr 2026 | Viewed by 353 | Submission Open
Keywords: hypogonadism; infertility; sex hormone deficiency; reproductive endocrinology; sexual health; assisted reproduction
(This special issue belongs to the Section Endocrinology & Metabolism)
Sarcoma—Clinical Updates: 2nd Edition
edited by
submission deadline 25 Apr 2026 | 1 articles | Viewed by 309 | Submission Open
Keywords: sarcoma; osteosarcoma; ewing’ s sarcoma; chondrosarcoma; soft-tissue sarcoma; undifferentiated pleo-morphic sarcoma; liposarcoma; leiomyosarcoma; rhabdomyosarcoma; metastatic sarcoma; targeted molecular therapy; immunotherapy; orthopedic oncology
(This special issue belongs to the Section Oncology)
New Concepts in Minimally Invasive Spine Surgery
edited by and Michael Y. Wang
submission deadline 25 Apr 2026 | 1 articles | Viewed by 256 | Submission Open
Keywords: minimally invasive spine surgery; image navigation; tubular retractor; endoscopic spine surgery; virtual and aug-mented reality; lateral spine surgery
(This special issue belongs to the Section Clinical Neurology)
Novel Diagnostic and Therapeutic Approaches to Urologic Oncology
edited by , Bogdan Florin Geavlete and
submission deadline 25 Apr 2026 | Viewed by 220 | Submission Open
Keywords: diagnosis; therapy; up-to-date; uro-oncologic pathology
(This special issue belongs to the Section Oncology)
Liver Failure: Current Status and Future Opportunities
edited by
submission deadline 25 Apr 2026 | Viewed by 107 | Submission Open
Keywords: acute liver failure; acute-on-chronic liver failure; portal hypertension; hepatic encephalopathy; pathogenesis; management
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
New Clinical Advances in Orthopedic Oncology
edited by
submission deadline 25 Apr 2026 | Viewed by 97 | Submission Open
Keywords: orthopedic oncology; sarcoma; soft-tissue sarcoma; osteosarcoma; chondrosarcoma; Ewings sarcoma; giant cell tumor; limb salvage; mega-prosthetic reconstruction; targeted molecular therapy; immunotherapy
(This special issue belongs to the Section Orthopedics)
Emerging Surgical Techniques in the Management of Urological Diseases
edited by
submission deadline 25 Apr 2026 | Viewed by 91 | Submission Open
Keywords: minimally invasive; robotics; partial nephrectomy; radical prostatectomy; focal therapy; benign prostatic hyperplasia; prostate cancer; bladder cancer
(This special issue belongs to the Section Nephrology & Urology)
Diagnosis, Treatment and Prognosis of Coronary Heart Disease: 2nd Edition
edited by
submission deadline 25 Apr 2026 | Viewed by 89 | Submission Open
Keywords: coronary heart disease; acute coronary syndrome; chronic coronary syndrome; ischemia with no obstructive coronary arteries (INOCA); guideline-directed optimal medical therapy; precision medicine; artificial intelligence; interventional cardiology; percutaneous coronary intervention (PCI)
(This special issue belongs to the Section Cardiology)
Advances in Reconstructive and Aesthetic Plastic Surgery
edited by
submission deadline 25 Apr 2026 | Viewed by 88 | Submission Open
Keywords: reconstructive plastic surgery; aesthetic innovation; fat grafting; microsurgery; regenerative medicine; cell-enriched lipotransfer; 3D imaging; minimally invasive techniques; hybrid injectables
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
Complex Scenarios in Reverse Shoulder Arthroplasty: Bone Loss, Revisions, and Surgical Solutions
edited by Francesco Franceschi, Angelo Baldari and Antonio Caldaria
submission deadline 25 Apr 2026 | Viewed by 71 | Submission Open
Keywords: shoulder arthroplasty; revision shoulder arthroplasty; humeral fracture; failed shoulder prosthesis; bone loss management; implant failure
(This special issue belongs to the Section Orthopedics)
Personalized Therapy and Clinical Outcome for Retinal Diseases
edited by
submission deadline 25 Apr 2026 | Viewed by 65 | Submission Open
Keywords: retinal diseases; retinal imaging; clinical outcomes; artificial intelligence; biomarkers; optical coherence tomography (OCT); vitrectomy
(This special issue belongs to the Section Ophthalmology)
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