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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Contemporary Oral and Maxillofacial Surgery: Expert Consensus and Best Practices
edited by
submission deadline 20 Mar 2026 | Viewed by 137 | Submission Open
Keywords: facial trauma; TMJ disorders; implant and sinus surgery; sleep apnea; cosmetic and reconstructive surgery
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Pediatric Otolaryngology: Clinical Advances and Challenges submission deadline 20 Mar 2026 | 1 articles | Viewed by 136 | Submission Open
Keywords: pediatric dizziness; laryngomalacia; subglottic stenosis; pediatric airway obstruction; intracapsular tonsillectomy; PITA (Powered Intracapsular Tonsillectomy and Adenoidectomy); pediatric sleep-disordered breathing; pediatric olfactory disorders; congenital anosmia
(This special issue belongs to the Section Clinical Pediatrics)
Emerging Radiotherapy Technologies and Trends
edited by
submission deadline 20 Mar 2026 | Viewed by 135 | Submission Open
Keywords: image-guided radiotherapy (IGRT); 4D radiotherapy; SBRT; radiomics; FLASH therapy; MR-guided radiotherapy
(This special issue belongs to the Section Oncology)
Rehabilitation in Musculoskeletal Disease
edited by
submission deadline 20 Mar 2026 | Viewed by 128 | Submission Open
Keywords: musculoskeletal disease; stroke rehabilitation; physical therapy; rehabilitation; chronic pain; manual therapy; exercise intervention
(This special issue belongs to the Section Clinical Rehabilitation)
Clinical Advances in Neurorehabilitation submission deadline 20 Mar 2026 | Viewed by 120 | Submission Open
Keywords: neurorehabilitation; robotics; artificial intelligence; neurodegenerative diseases; Parkinson’ s disease; stroke
(This special issue belongs to the Section Clinical Rehabilitation)
Recent Advances in Vitreoretinal Surgery: 2nd Edition
edited by
submission deadline 20 Mar 2026 | Viewed by 119 | Submission Open
Keywords: vitrectomy; retinal detachment; macular holes; pediatric vitreoretinal surgery; vitrectomy instrumentation; macular surgery; complex retinal detachments; vitreoretinal surgery
(This special issue belongs to the Section Ophthalmology)
Clinical Advances in Prosthetic Joint Infection
edited by
submission deadline 20 Mar 2026 | Viewed by 115 | Submission Open
Keywords: total hip revision; total knee revision; complications; periprosthetic joint infections; diagnostics
(This special issue belongs to the Section Orthopedics)
Advances in the Field of Radiation Oncology: An Update
edited by and
submission deadline 20 Mar 2026 | Viewed by 112 | Submission Open
Keywords: radiation oncology; image-guided radiotherapy (IGRT); immunotherapy; machine learning; radiation
(This special issue belongs to the Section Oncology)
Clinical Applications of Echocardiographic Techniques in Cardiovascular Diagnostics
edited by Gianpiero Italiano and
submission deadline 20 Mar 2026 | Viewed by 112 | Submission Open
Keywords: echocardiography; cardiovascular diagnostics; 3D echocardiography; strain imaging; speckle-tracking echocardi-ography; valvular heart disease; heart failure; interventional echocardiography; stress echocardiography; car-dio-oncology; artificial intelligence
(This special issue belongs to the Section Cardiovascular Medicine)
Clinical Management in Chronic Pain: Innovations, Integration, and Interventions
edited by Giuliano Lo Bianco, Silvia Natoli and Sean Li
submission deadline 20 Mar 2026 | Viewed by 108 | Submission Open
Keywords: chronic pain; clinical management; interventional pain medicine; spinal cord stimulation; regenerative medicine; diagnostic strategies; pain semeiotics; multidisciplinary approaches; personalized medicine; pain assessment; neuromodulation; evidence-based pain therapy
(This special issue belongs to the Section Clinical Neurology)
Machine Learning in Vascular Surgery submission deadline 20 Mar 2026 | Viewed by 107 | Submission Open
Keywords: machine learning; artificial intelligence; vascular surgery
(This special issue belongs to the Section Vascular Medicine)
Bladder Cancer: Diagnosis and Treatments submission deadline 20 Mar 2026 | Viewed by 105 | Submission Open
Keywords: bladder cancer; urothelial cancer; radical cystectomy; targeted therapy; immunotherapy; non-muscle -invasive; muscle-invasive; chemotherapy
(This special issue belongs to the Section Nephrology & Urology)
Perspectives on the Diagnosis and Treatment of Cardiomyopathies
edited by Luca Arcari
submission deadline 20 Mar 2026 | Viewed by 104 | Submission Open
Keywords: cardiomyopathies; hypertrophic cardiomyopathy; dilated cardiomyopathy; cardiac amyloidosis; arrhythmogenic right ventricular cardiomyopathy; non-dilated left ventricular cardiomyopathy; cardiac magnetic resonance imaging; computed tomography; echocardiography; nuclear imaging
(This special issue belongs to the Section Cardiology)
Minimally Invasive and Endoscopic Neurosurgery
edited by , Vassilios Tsitouras and Stylianos Kapetanakis
submission deadline 20 Mar 2026 | Viewed by 104 | Submission Open
Keywords: traumatic brain injury; neuro-oncology; hydrocephalus and cerebrospinal fluid disorders; neuroendoscopy; endo-scopic neurosurgery; skull base surgery; vascular neurosurgery; functional neurosurgery; pediatric neurosurgey; minimally invasive spine surgery; endoscopic spine surgery; spine endoscopy
(This special issue belongs to the Section Clinical Neurology)
Periodontitis and Systemic Health: Exploring the Oral-Systemic Connection
edited by and Phoebus Madianos
submission deadline 20 Mar 2026 | Viewed by 103 | Submission Open
Keywords: periodontal disease; systemic diseases; cardiovascular disease; diabetes mellitus; adverse pregnancy outcomes; respiratory disease; neurodegenerative disorders; obesity; respiratory diseases; chronic kidney disease
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Clinical Challenges and Future Directions of Interstitial Lung Disease
edited by
submission deadline 20 Mar 2026 | Viewed by 100 | Submission Open
Keywords: interstitial lung disease; progressive pulmonary fibrosis; early detection; clinical diagnosis; multidisciplinary discussion; treatment; non-pharmacological therapy; end-of-life care; patient-centered management
(This special issue belongs to the Section Respiratory Medicine)
Atrial Fibrillation: Screening, Management and Outcomes
edited by Ahmed AlTurki and Vidal Essebag
submission deadline 20 Mar 2026 | Viewed by 99 | Submission Open
Keywords: atrial fibrillation; ablation; pulmonary vein isolation; atrial fibrillation screening; wearable devices; anti-arrhythmic drugs; cardiovascular outcomes; subclinical atrial fibrillation
(This special issue belongs to the Section Cardiology)
Advances in Diagnosis and Treatment of Endometriosis
edited by and
submission deadline 20 Mar 2026 | Viewed by 98 | Submission Open
Keywords: endometriosis; adenomyosis; diagnosis; classification; therapy; progesterone
(This special issue belongs to the Section Obstetrics & Gynecology)
Exercise and Chronic Pain
edited by Nuria Marín-Jiménez and Milkana Borges-Cosic
submission deadline 20 Mar 2026 | Viewed by 93 | Submission Open
Keywords: chronic pain; exercise therapy; physical activity; fitness; pain management; quality of life; non-pharmacological interventions
(This special issue belongs to the Section Sports Medicine)
Clinical Advances in Maternal–Fetal Medicine: 2nd Edition
edited by
submission deadline 20 Mar 2026 | Viewed by 91 | Submission Open
Keywords: precision medicine; omics; clinical; fetus; Doppler
(This special issue belongs to the Section Obstetrics & Gynecology)
Clinical Advances in Laryngeal Cancer submission deadline 20 Mar 2026 | Viewed by 88 | Submission Open
Keywords: head and neck cancer (HNC); laryngeal cancer; larynx organ preservation; immuno-oncology; biomarker; prognostic factor; genetic risk factors; outcome research
(This special issue belongs to the Section Otolaryngology)
Acute Cardiovascular Care in Cardio-Oncology: Present Challenges and Future Pathways
edited by and Maria Bergami
submission deadline 20 Mar 2026 | Viewed by 86 | Submission Open
Keywords: cardiotoxicity; cardio-oncology; acute cardiovascular care; acute cardiovascular complications; disparities in care
(This special issue belongs to the Section Cardiovascular Medicine)
Current Challenges in Oral Surgery and Pathology
edited by
submission deadline 20 Mar 2026 | Viewed by 84 | Submission Open
Keywords: oral medicine; oral pathology; oral surgery; ONJ; MRONJ; BRONJ; laser
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Minimally Invasive Thoracic Surgery: State of the Art and Future Perspectives
edited by Dustin M. Walters
submission deadline 20 Mar 2026 | Viewed by 84 | Submission Open
Keywords: thoracic surgery; perioperative outcomes; lung cancer resection; minimally invasive surgery; robotic thoracic surgery
(This special issue belongs to the Section Respiratory Medicine)
Emerging Insights into Glaucoma, Cataracts, and Refractive Surgery
edited by
submission deadline 20 Mar 2026 | Viewed by 81 | Submission Open
Keywords: trabeculoplasty; MIGS; MIBS; trabeculectomy; IOL; biometry; phacoemulsification; femto-cataract; refractive cataract; excimer laser; PRK; femto; LASIK; SMILE; aberrometry; tomography
(This special issue belongs to the Section Ophthalmology)
Bridging Bench, Bedside, and Beyond: Clinical and Translational Strategies for Pregnancy Complications
edited by and Federica Piani
submission deadline 20 Mar 2026 | Viewed by 75 | Submission Open
Keywords: high-risk pregnancy; cardiovascular complications; cardiometabolic complications; gestational diabetes; pregnancy complications; preeclampsia; hypertension; vascular disorders; endothelial dysfunction; clinical prediction; antenatal diagnosis; personalized treatment
(This special issue belongs to the Section Obstetrics & Gynecology)
Intracranial Aneurysms: What Do We Know So Far?
edited by Alessio Albanese and Giuseppe Esposito
submission deadline 20 Mar 2026 | Viewed by 75 | Submission Open
Keywords: intracranial aneurysms; clipping; endovascular therapy; stenting; coiling; cerebral vasospasm; cerebrovascular diseases; microneurosurgery; subarachnoid hemorrhage; bypass
(This special issue belongs to the Section Clinical Neurology)
Emerging Research in Cancer Survivorship
edited by
submission deadline 20 Mar 2026 | Viewed by 74 | Submission Open
Keywords: cancer survivorship; clinical epidemiology; quality of life; health system; sexual health; mental health; comorbidities; pain management; tobacco cessation; alcohol abstinence; diet
(This special issue belongs to the Section Epidemiology & Public Health)
Advancements and Challenges in Retina Surgery: Second Edition
edited by Joaquín Marticorena and
submission deadline 20 Mar 2026 | Viewed by 68 | Submission Open
Keywords: retina; vitreoretinal diseases; vitreotomes; optical coherence tomography; vitreoretinal surgery
(This special issue belongs to the Section Ophthalmology)
Updates in the Use of Pharmacogenetics in Clinical Practice
edited by Rocío Morón Romero and Xando Díaz-Villamarín
submission deadline 20 Mar 2026 | Viewed by 63 | Submission Open
Keywords: pharmacogenetics; personalized medicine; clinical implementation; drug response; pharmacogenomics; precision medicine; healthcare integration; decision support; clinical implications of genetic testing
(This special issue belongs to the Section Pharmacology)
Current Paradigms in Pulmonary Vascular Disease: Past, Present and Future
edited by Parth M. Rali
submission deadline 20 Mar 2026 | Viewed by 62 | Submission Open
Keywords: pulmonary hypertension (PH); pulmonary embolism (PE); rare pulmonary vascular disorders; novel therapeutics; di-agnostic innovations
(This special issue belongs to the Section Respiratory Medicine)
Advances and Challenges in Colorectal Cancer
edited by Vignesh Narasimhan
submission deadline 20 Mar 2026 | Viewed by 61 | Submission Open
Keywords: anal fistula; advancement flap; ‎ ligation of intersphincteric tract; haemorrhoid surgery; pilonidal surgery
(This special issue belongs to the Section Oncology)
Rectal Cancer: Screening, Treatment and Prevention
edited by Fernando Mendoza-Moreno
submission deadline 20 Mar 2026 | Viewed by 50 | Submission Open
Keywords: rectal cancer; cancer screening; neoadjuvant therapy; minimally invasive surgery; oncologic outcomes; multidiscipli-nary care; health disparities
(This special issue belongs to the Section Oncology)
Clinical Updates and Perspectives on Subarachnoid Hemorrhage: 2nd Edition
edited by
submission deadline 20 Mar 2026 | Viewed by 45 | Submission Open
Keywords: subarachnoid hemorrhage; outcome of subarachnoid hemorrhage; delayed cerebral ischemia; ruptured cerebral aneurysm; unruptured cerebral aneurysm; artificial intelligence; epidemiology
(This special issue belongs to the Section Clinical Neurology)
Personalized Medicine and Treatment in Inflammatory Bowel Diseases
edited by Carmen Monica Preda and
submission deadline 21 Mar 2026 | Viewed by 101 | Submission Open
Keywords: personalized medicine; inflammatory bowel diseases (IBDs); Crohn’ s disease; ulcerative colitis; biomarkers; pharmacogenomics; microbiome; anti-TNF therapy; precision medicine; machine learning
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Clinical Perspectives on Foot and Ankle Surgery
edited by Kenichiro Nakajima
submission deadline 24 Mar 2026 | 3 articles | Viewed by 7328 | Submission Open
Keywords: foot and ankle; minimally invasive surgery; surgical techniques; new technologies; diagnosis; clinical assessment
(This special issue belongs to the Section Orthopedics)
Orthodontics: Current Advances and Future Options submission deadline 25 Mar 2026 | 23 articles | Viewed by 44128 | Submission Open
Keywords: digital orthodontics; functional devices; cranial growth; orthodontic therapy; customized devices
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Musculoskeletal Disorders: Clinical Diagnosis, Treatment and Rehabilitation submission deadline 25 Mar 2026 | 7 articles | Viewed by 27428 | Submission Open
Keywords: musculoskeletal disorders; therapeutic exercise; functional evaluation; rehabilitation protocols; musculoskeletal ultrasound; biomechanical aná lisis; quality of life; functional assessment of the musculoskeletal system; strength training; physical therapy; morphofunctional assessment; conservative treatments; range of motion evaluation; randomized controlled trials
(This special issue belongs to the Section Clinical Rehabilitation)
New Directions for Treatment and Assessment of Ulcerative Colitis submission deadline 25 Mar 2026 | 4 articles | Viewed by 19728 | Submission Open
Keywords: treatment; ulcerative colitis; treatment target; ultrasound assessment; approach
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Advancements in Venous Disease Management: From Conservative to Interventional Treatments
edited by and Chiara Lomazzi
submission deadline 25 Mar 2026 | 2 articles | Viewed by 13755 | Submission Open
Keywords: chronic venous disease; varicose veins; venoactive drugs; saphenous vein; venous stent; iliac vein; compression therapy; venous insufficiency
(This special issue belongs to the Section Vascular Medicine)
New Technologies and Translational Approach for an Early Diagnosis of Bipolar Spectrum and Hyperactive and Novelty Seeking Profiles
edited by , Serdar Dursun and
submission deadline 25 Mar 2026 | 4 articles | Viewed by 11347 | Submission Open
Keywords: psychiatry; mental health; bipolar disorders; mood; biomarkers; new technology; BD
(This special issue belongs to the Section Mental Health)
Clinical Management for Metabolic Syndrome and Obesity
edited by and Antonio De Arriba-Muñoz
submission deadline 25 Mar 2026 | 5 articles | Viewed by 11078 | Submission Open
Keywords: obesity; metabolic syndrome; estatosis hepatic; diabetes mellitus; children; GLP-1
(This special issue belongs to the Section Endocrinology & Metabolism)
Current Advances in Aortic Valve Stenosis
edited by
submission deadline 25 Mar 2026 | 6 articles | Viewed by 10065 | Submission Open
Keywords: valvular heart diseases; aortic stenosis; prevention; diagnosis; management
(This special issue belongs to the Section Cardiology)
Advances in Stigma and Discrimination in Pediatric Mental Health submission deadline 25 Mar 2026 | 4 articles | Viewed by 9132 | Submission Open
Keywords: stigma; discrimination; childhood; mental health; clinical psychology
(This special issue belongs to the Section Mental Health)
Innovations and Advances in Breast Cancer Research and Treatment
edited by
submission deadline 25 Mar 2026 | 5 articles | Viewed by 8925 | Submission Open
Keywords: breast cancer; early detection; genomics; personalized medicine; targeted therapies; survivorship; quality of life; artificial intelligence; machine learning; immunotherapy
(This special issue belongs to the Section Oncology)
Airway Management: From Basic Techniques to Innovative Technologies
edited by Kunal Karamchandani and Sheila Nainan Myatra
submission deadline 25 Mar 2026 | 5 articles | Viewed by 8243 | Submission Open
Keywords: airway management; physiologically difficult airway; videolaryngoscopy; esophageal intubation; artificial intelligence
(This special issue belongs to the Section Intensive Care)
Psoriasis and Psoriatic Arthritis: How to Treat in the Era of Biologics and Small Molecule Inhibitors: 3rd Edition submission deadline 25 Mar 2026 | 2 articles | Viewed by 7052 | Submission Open
Keywords: psoriasis; psoriatic arthritis; biologics; small molecule inhibitors; conventional therapies
(This special issue belongs to the Section Dermatology)
Innovations in Head and Neck Surgery
edited by and Giovanni Badiali
submission deadline 25 Mar 2026 | 3 articles | Viewed by 6856 | Submission Open
Keywords: reconstructive surgery; head and neck surgery; 3D printing; new technologies; virtual surgical planning; computer-assisted surgery; personalized reconstructive surgery; patient-specific implants; augmented reality; artificial intelligence; robotic surgery; surgical navigation
(This special issue belongs to the Section Otolaryngology)
Biomarkers and Diagnostics in Neurological Diseases
edited by Maria Ioanna Stefanou
submission deadline 25 Mar 2026 | 5 articles | Viewed by 6746 | Submission Open
Keywords: biomarkers; neurological diseases; diagnosis; lipoprotein(a); neurofilament protein; tau peptide; neuroimaging
(This special issue belongs to the Section Clinical Neurology)
Cardiac Surgery: Clinical Advances
edited by Carmelo Dominici, Giovanni Casali and
submission deadline 25 Mar 2026 | 5 articles | Viewed by 6146 | Submission Open
Keywords: cardiac surgery; surgical innovation; minimally invasive techniques; robotic surgery; personalized medicine; advanced surgical technologies
(This special issue belongs to the Section Cardiology)
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