Clinical Management for Metabolic Syndrome and Obesity

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Endocrinology & Metabolism".

Deadline for manuscript submissions: 30 September 2025 | Viewed by 1741

Special Issue Editors


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Guest Editor
Unidad de Endocrinología Pediátrica, Hospital Universitario Araba, 01004 Vitoria-Gasteiz, Spain
Interests: pediatric endocrinology; small for gestational age; vitamin D deficiency
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Guest Editor
1. Instituto Investigación Sanitaria Aragón, Avenida San Juan Bosco, 50009 Zaragoza, Spain
2. Miguel Servet University Hospital, 50009 Zaragoza, Spain
Interests: pediatric endocrinology; growth hormone; endocrinology and metabolism

Special Issue Information

Dear Colleagues,

It is our honor and pleasure to present you with this Special Issue of the Journal of Clinical Medicine. Obesity in general, and childhood obesity in particular, has been defined as the great pandemic at the beginning of this century. The other great pandemic, COVID-19, has not only endorsed the need to act globally in the face of a health challenge but has also led to an increase in cases of obesity and metabolic syndrome after the obligatory period of quarantine at home. In particular, childhood obesity is as prevalent as 30–50% in some southern European, American, and even developing country populations. These children suffering from obesity will be sick as adults. However, we are also starting to experience typical adult diseases in pediatrics, such as type 2 DM.

The emergence of new diagnostic challenges, new screening tests and studies, the significance of non-alcoholic fatty liver disease, and, of course, the tide of new GLP-1-type drugs that are appearing will not only change the paradigm of diagnosis and monitoring of these patients but will also bring hope for the future.

We look forward to receiving your submissions to this Special Issue.

Dr. Ignacio Díez López
Dr. Antonio De Arriba-Muñoz
Guest Editors

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Keywords

  • obesity
  • metabolic syndrome
  • estatosis hepatic
  • diabetes mellitus
  • children
  • GLP-1

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Published Papers (2 papers)

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Research

13 pages, 1190 KiB  
Article
Obesity-Related Disorders in Türkiye: A Multi Center, Retrospective, Cross-Sectional Analysis from the OBREDI-TR Study
by Alihan Oral, Ihsan Solmaz, Nizameddin Koca, Ulas Serkan Topaloglu, Ismail Demir, Ahmet Dundar, Ali Kirik, Ozge Kama Basci, Hacer Sen, Emine Binnetoglu, Nalan Okuroglu, Ahmet Aydin, Zeynep Irmak Kaya, Hamit Yildiz, Aycan Acet, Gokhan Tazegul, Hasan Sozel, Osman Ozudogru, Kubilay Issever, Selcuk Yaylacı, Ugur Bayram Korkmaz, Nur Duzen Oflas, Celalettin Küçük, Kamil Konur, Teslime Ayaz, Aysun Isiklar, Esref Arac, Hilmi Erdem Sumbul, Huseyin Ali Ozturk, Ali Burak Govez, Yusuf Usame Durmus, Atilla Onmez, Sibel Ocak Serin, Nazif Yalcin, Aysegul Ertinmaz, Alper Tuna Guven, Mehmet Kok, Yasin Sahinturk and Seyit Uyaradd Show full author list remove Hide full author list
J. Clin. Med. 2025, 14(8), 2680; https://doi.org/10.3390/jcm14082680 - 14 Apr 2025
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Abstract
Objectives: Obesity is a significant public health concern, as it is associated with the development of numerous chronic diseases. The prevalence of obesity and attendant diseases has been increasing over recent years. This study attempted to ascertain the frequency of chronic diseases [...] Read more.
Objectives: Obesity is a significant public health concern, as it is associated with the development of numerous chronic diseases. The prevalence of obesity and attendant diseases has been increasing over recent years. This study attempted to ascertain the frequency of chronic diseases in obese patients in Türkiye for the first time on this scale. Methods: A retrospective study was conducted, with patients admitted to the internal medicine outpatient clinics or obesity centers between December 2023 and December 2024 included in this study. Participants were recruited from seven regions, 20 provinces, and 28 centers, and the inclusion criteria were met by those aged 18 years and over with a body mass index (BMI) of 30 kg per square meter (kg/m2) or above. Their status, with respect to chronic diseases, and their anthropometric parameters were documented. Results: The total number of patients was 10,121, with a mean age of 45.2 ± 13.92. Of these, 7222 (71.35%) were female. The prevalence of type 2 diabetes mellitus (T2DM), hypertension (HT), dyslipidemia (DL), coronary artery disease (CAD), obstructive pulmonary disease (OPD), obstructive sleep apnea syndrome (OSAS), and fatty liver disease (FLD) was found to be 35.01%, 78.19%, 12.37%, 10.32%, 5.88%, and 75.12%, respectively. A subsequent analysis of the prevalence of these diseases by region revealed a statistically significant variation between regions (p < 0.001 for all regions). Conclusions: This study represents a substantial contribution to the existing body of knowledge in this field, particularly with regard to the identification of the current chronic disease rate of obese patients in Türkiye. Full article
(This article belongs to the Special Issue Clinical Management for Metabolic Syndrome and Obesity)
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11 pages, 812 KiB  
Article
Factors Affecting the Unconscious Bias of Healthcare Professionals in Obesity Care
by Jana Makuc, Ana Ogrič Lapajne, Špela Hvalec, Mojca Jensterle and Andrej Janež
J. Clin. Med. 2025, 14(5), 1486; https://doi.org/10.3390/jcm14051486 - 23 Feb 2025
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Abstract
Background/Objectives: To assess the factors affecting the unconscious bias of healthcare professionals (HCPs) in obesity care. Methods: A cross-sectional, non-interventional, descriptive study collecting data via an online survey system was distributed via e-mail to 11,597 members of the Medical Chamber of [...] Read more.
Background/Objectives: To assess the factors affecting the unconscious bias of healthcare professionals (HCPs) in obesity care. Methods: A cross-sectional, non-interventional, descriptive study collecting data via an online survey system was distributed via e-mail to 11,597 members of the Medical Chamber of Slovenia. Physicians were assigned into six HCP categories: (junior) resident physicians, primary care physicians (PCPs), internal medicine specialists, surgeons, dentists, and others. The online questionnaire was active for two weeks. Results: A total of 1248 physicians opened the survey link (10.8% response rate). Of the 898 physicians that engaged in the survey, 789 fully completed the questionnaire. Out of those physicians, 93.6% agreed that obesity is a disease, 83.7% were familiar with the definition, and 75.5% of HCPs were professionally interested in the subject. Overall, 39% of HCPs use the ICD obesity code, primarily primary care physicians and specialists in internal medicine. Notably, 82.0% of HCPs identified lifestyle change as the most effective intervention and believed that patients could lose weight with a serious attempt at a lifestyle change. This belief was particularly supported by male HCPs and HCPs under 40 years of age, who felt that patients were entirely responsible for their weight. The unconscious bias decreased with an increase in the HCPs’ body mass index (BMI), but at the same time, physicians with a higher BMI found obesity to be less important than other diseases (p = 0.036). Using composite answers, we found that the unconscious bias of HCPs toward obesity and effective obesity care was significantly related to gender (p = 0.017), age (p < 0.001), and BMI (p = 0.005), and was independent of an area of expertise. Conclusions: HCPs’ area of expertise impacted their professional standpoint (suggesting conscious bias), whereas male gender, a younger age, and a lower BMI affected unconscious bias toward obesity and its effective care. Despite their limitations, including the self-reported nature of the data, our findings can help to individualize educational strategies and create a more equitable environment in obesity healthcare. Full article
(This article belongs to the Special Issue Clinical Management for Metabolic Syndrome and Obesity)
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