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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Liquid Biopsies in Oral Cancer: Advances and New Perspectives

edited by

Óscar Rapado-González

submission deadline 20 Mar 2026 | 1 articles | Viewed by 1030 | Submission Open

Keywords: oral cancer; oral potentially malignant disorders; liquid biopsies; saliva and blood biomarkers; circulating tumor cells (CTCs); cell-free DNA (cfDNA)/circulating tumor DNA (ctDNA); cell-free RNA (cfRNA); extracellular vesicles (EVs); genetic and epigenetic biomarkers; early detection; prognosis and therapy response prediction; precision medicine

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Fresh Insights in Skin Disease

edited by

Claudio Marasca

submission deadline 20 Mar 2026 | 1 articles | Viewed by 922 | Submission Open

Keywords: inflammatory dermatoses; dermoscopy; melanoma; autoimmune skin conditions; psoriasis; skin cancers; skin syndromes

(This special issue belongs to the Section Dermatology)

Minimally Invasive Surgery: Challenges and Solutions in Clinical Practice

edited by

Giuseppe Cavallaro

and Alessia Fassari

submission deadline 20 Mar 2026 | 1 articles | Viewed by 816 | Submission Open

Keywords: laparoscopic surgery; minimally invasive surgery; surgical challenges; clinical practice; surgical training; robotic-assisted surgery; artificial intelligence in surgery; laparoscopic instrumentation; intraoperative complications; surgical innovation; skill enhancement; surgical outcomes

(This special issue belongs to the Section General Surgery)

Esophageal and Upper Interventional Endoscopy and Surgery: Latest Advances and Prospects

edited by Giulia Gibiino

submission deadline 20 Mar 2026 | 1 articles | Viewed by 769 | Submission Open

Keywords: gastric preneoplastic and neoplastic lesions; endoscopic submucosal dissection (ESD); endoscopic full-thickness resection (EFTR); subepithelial upper GI lesions; duodenal adenomas; esophageal stenting

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Clinical Advances in Obesity and Bariatric Surgery—2nd Edition

edited by Valentin Mocanu and Jerry Dang

submission deadline 20 Mar 2026 | 1 articles | Viewed by 769 | Submission Open

Keywords: obesity; bariatric surgery; metabolic surgery; anti-obesity medications; obesity treatment

(This special issue belongs to the Section Endocrinology & Metabolism)

New Advances in Clinical Epidemiological Research Methods

edited by

Dorota Sys

and Anna Scholz

submission deadline 20 Mar 2026 | 1 articles | Viewed by 746 | Submission Open

Keywords: clinical epidemiology; research methodology; observational studies; causal inference; real-world data; machine learning; bias control

(This special issue belongs to the Section Clinical Research Methods)

Clinical Advances in Autism Management

edited by

Justyna Podgórska-Bednarz

submission deadline 20 Mar 2026 | 1 articles | Viewed by 529 | Submission Open

Keywords: autism spectrum disorder; diagnosis; child; adult; youth; early intervention; therapy; epidemiology; relatives; resources; limitations; problems; health; epidemiology; perspectives; organization

(This special issue belongs to the Section Mental Health)

Innovations in Emergency and Critical Care Medicine

edited by Yoshiaki Iwashita

submission deadline 20 Mar 2026 | Viewed by 506 | Submission Open

Keywords: emergency; artificial intelligence; Tele-ICU; point of care; electrical impedance tomography

(This special issue belongs to the Section Intensive Care)

Latest Advances in Minimally Invasive Spine Surgery

edited by Fabian Sommer and

Roger Härtl

submission deadline 20 Mar 2026 | 1 articles | Viewed by 476 | Submission Open

Keywords: minimally invasive spine surgery (MISS); advances in spine surgery; future directions of MISS; navigation and orientation; intramedullary/extramedullary tumor resections; emerging technologies in MISS (robotics; augmented reality; artificial intelligence; etc.); degenerative spine; patient safety in MISS

(This special issue belongs to the Section Clinical Neurology)

Challenges and Innovations in Thrombosis and Haemostasis

edited by Vasiliki Danilatou and Fotios I. Girtovitis

submission deadline 20 Mar 2026 | Viewed by 404 | Submission Open

Keywords: air pollution and thrombosis; antiphospholipid syndrome; antithrombotic therapy; arterial thrombosis; artificial intelligence in thrombosis and haemostasis; biology of arterial thrombosis; biomarkers in thrombosis and haemostasis; cancer-associated thrombosis; clinical decision support; current concepts and novel targets for antiplatelet treatments; digital health in heamostasis and thrombosis; endotheliopathy and thrombosis; ethical challenges in thrombosis care; hemophilia and von willebrand disease; innovative therapies in thrombosis and haemostasis; pediatric thrombosis; platelet biology and function: new concepts and clinical perspectives; rare blood disorders; thrombophilia; thrombosis and hemostasis guidelines; thrombosis in pregnancy; thrombo-inflammation; trauma-induced coagulopathy; venous thromboembolism

(This special issue belongs to the Section Vascular Medicine)

Recent Advances in Head and Neck Surgery

edited by Lisa Catarzi,

Olindo Massarelli

and

Guido Gabriele

submission deadline 20 Mar 2026 | Viewed by 345 | Submission Open

Keywords: head and neck surgery; reconstructive surgery; microsurgical reconstruction; new technologies; computer-assisted surgery; surgical innovation; post-operative care

(This special issue belongs to the Section Otolaryngology)

Maxillomandibular Growth, Reconstruction and Rehabilitation: Orthodontic, Prosthodontic and Surgical Interventions from Childhood to Adulthood

edited by Kamila Chęcińska and

Maciej Sikora

submission deadline 20 Mar 2026 | 1 articles | Viewed by 326 | Submission Open

Keywords: maxillomandibular growth; orthodontics; prosthodontics; surgical interventions; childhood; adulthood; reconstruction; rehabilitation

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Treatment Strategies for Prostate Cancer: An Update

edited by

Antonio Andrea Grosso

submission deadline 20 Mar 2026 | 1 articles | Viewed by 223 | Submission Open

Keywords: prostate cancer; robotic surgery; uro-oncology; focal therapy; single-port; radiotherapy

(This special issue belongs to the Section Nephrology & Urology)

Up-to-Date Research on Nerve Ultrasound

edited by

Hubertus Axer

and Eman A. Tawfik

submission deadline 20 Mar 2026 | Viewed by 183 | Submission Open

Keywords: peripheral nerve ultrasound; polyneuropathy; nerve trauma; plexus neuritis; nerve tumors; entrapment syndromes; ultrasound techniques; guidelines

(This special issue belongs to the Section Clinical Neurology)

Vertigo and Dizziness in Children: Clinical Updates

edited by

Eduardo Martin Sanz

submission deadline 20 Mar 2026 | Viewed by 175 | Submission Open

Keywords: vertigo; dizziness; children; vestibular disorders; otorhinolaryngology

(This special issue belongs to the Section Clinical Pediatrics)

Clinical Advances in Musculoskeletal Disorders: 2nd Edition

edited by

Peter V. Giannoudis

and Sushrut Babhulkar

submission deadline 20 Mar 2026 | Viewed by 163 | Submission Open

Keywords: musculoskeletal disorders; disability; pain; inflammation; arthritis

(This special issue belongs to the Section Clinical Rehabilitation)

Modern Gynecological Surgery: Clinical Updates and Perspectives

edited by

Rudy Leon De Wilde

Harald Krentel

and Maya Sophie de Wilde

submission deadline 20 Mar 2026 | Viewed by 156 | Submission Open

Keywords: gynecological diseases; gynecological surgery; surgical options; individual treatment; women’ s health care

(This special issue belongs to the Section Obstetrics & Gynecology)

Postpartum Depression: What Happened to My Wife?

edited by

Sara Albuquerque

, Ana Filipa Beato and

Stephanie Alves

submission deadline 20 Mar 2026 | Viewed by 147 | Submission Open

Keywords: postpartum depression; clinical and health psychology; perinatal trauma; clinical and health psychology; mental health and quality of life

(This special issue belongs to the Section Mental Health)

Update on Minimally Invasive Gynecologic Surgery

edited by

Greg J. Marchand

submission deadline 20 Mar 2026 | Viewed by 147 | Submission Open

Keywords: minimally invasive gynecologic surgery (MIGS); obstetrics and gynecology; single-port laparoscopy; hysterectomy; robotic surgery

(This special issue belongs to the Section Obstetrics & Gynecology)

Contemporary Oral and Maxillofacial Surgery: Expert Consensus and Best Practices

edited by

Jae-Yeol Lee

submission deadline 20 Mar 2026 | Viewed by 136 | Submission Open

Keywords: facial trauma; TMJ disorders; implant and sinus surgery; sleep apnea; cosmetic and reconstructive surgery

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Emerging Radiotherapy Technologies and Trends

edited by

Michele Fiore

submission deadline 20 Mar 2026 | Viewed by 133 | Submission Open

Keywords: image-guided radiotherapy (IGRT); 4D radiotherapy; SBRT; radiomics; FLASH therapy; MR-guided radiotherapy

(This special issue belongs to the Section Oncology)

Rehabilitation in Musculoskeletal Disease

edited by

Youngsook Bae

submission deadline 20 Mar 2026 | Viewed by 125 | Submission Open

Keywords: musculoskeletal disease; stroke rehabilitation; physical therapy; rehabilitation; chronic pain; manual therapy; exercise intervention

(This special issue belongs to the Section Clinical Rehabilitation)

Pediatric Otolaryngology: Clinical Advances and Challenges

edited by

Manabu Komori

and

Masaomi Motegi

submission deadline 20 Mar 2026 | Viewed by 121 | Submission Open

Keywords: pediatric dizziness; laryngomalacia; subglottic stenosis; pediatric airway obstruction; intracapsular tonsillectomy; PITA (Powered Intracapsular Tonsillectomy and Adenoidectomy); pediatric sleep-disordered breathing; pediatric olfactory disorders; congenital anosmia

(This special issue belongs to the Section Clinical Pediatrics)

Recent Advances in Vitreoretinal Surgery: 2nd Edition

edited by

Lihteh Wu

submission deadline 20 Mar 2026 | Viewed by 117 | Submission Open

Keywords: vitrectomy; retinal detachment; macular holes; pediatric vitreoretinal surgery; vitrectomy instrumentation; macular surgery; complex retinal detachments; vitreoretinal surgery

(This special issue belongs to the Section Ophthalmology)

Clinical Advances in Prosthetic Joint Infection

edited by

Mattia Loppini

submission deadline 20 Mar 2026 | Viewed by 115 | Submission Open

Keywords: total hip revision; total knee revision; complications; periprosthetic joint infections; diagnostics

(This special issue belongs to the Section Orthopedics)

Clinical Advances in Neurorehabilitation

edited by

Giuliana Vezzadini

and

Michela Candini

submission deadline 20 Mar 2026 | Viewed by 112 | Submission Open

Keywords: neurorehabilitation; robotics; artificial intelligence; neurodegenerative diseases; Parkinson’ s disease; stroke

(This special issue belongs to the Section Clinical Rehabilitation)

Advances in the Field of Radiation Oncology: An Update

edited by

Jack Phan

and

Anna Lee

submission deadline 20 Mar 2026 | Viewed by 109 | Submission Open

Keywords: radiation oncology; image-guided radiotherapy (IGRT); immunotherapy; machine learning; radiation

(This special issue belongs to the Section Oncology)

Clinical Applications of Echocardiographic Techniques in Cardiovascular Diagnostics

edited by Gianpiero Italiano and

Laura Fusini

submission deadline 20 Mar 2026 | Viewed by 109 | Submission Open

Keywords: echocardiography; cardiovascular diagnostics; 3D echocardiography; strain imaging; speckle-tracking echocardi-ography; valvular heart disease; heart failure; interventional echocardiography; stress echocardiography; car-dio-oncology; artificial intelligence

(This special issue belongs to the Section Cardiovascular Medicine)

Clinical Management in Chronic Pain: Innovations, Integration, and Interventions

edited by Giuliano Lo Bianco, Silvia Natoli and Sean Li

submission deadline 20 Mar 2026 | Viewed by 106 | Submission Open

Keywords: chronic pain; clinical management; interventional pain medicine; spinal cord stimulation; regenerative medicine; diagnostic strategies; pain semeiotics; multidisciplinary approaches; personalized medicine; pain assessment; neuromodulation; evidence-based pain therapy

(This special issue belongs to the Section Clinical Neurology)

Machine Learning in Vascular Surgery

edited by

George N. Kouvelos

Konstantinos Spanos

and

Konstantinos Dakis

submission deadline 20 Mar 2026 | Viewed by 105 | Submission Open

Keywords: machine learning; artificial intelligence; vascular surgery

(This special issue belongs to the Section Vascular Medicine)

Minimally Invasive and Endoscopic Neurosurgery

edited by

Nikolaos Gkantsinikoudis

, Vassilios Tsitouras and Stylianos Kapetanakis

submission deadline 20 Mar 2026 | Viewed by 104 | Submission Open

Keywords: traumatic brain injury; neuro-oncology; hydrocephalus and cerebrospinal fluid disorders; neuroendoscopy; endo-scopic neurosurgery; skull base surgery; vascular neurosurgery; functional neurosurgery; pediatric neurosurgey; minimally invasive spine surgery; endoscopic spine surgery; spine endoscopy

(This special issue belongs to the Section Clinical Neurology)

Perspectives on the Diagnosis and Treatment of Cardiomyopathies

edited by Luca Arcari

submission deadline 20 Mar 2026 | Viewed by 103 | Submission Open

Keywords: cardiomyopathies; hypertrophic cardiomyopathy; dilated cardiomyopathy; cardiac amyloidosis; arrhythmogenic right ventricular cardiomyopathy; non-dilated left ventricular cardiomyopathy; cardiac magnetic resonance imaging; computed tomography; echocardiography; nuclear imaging

(This special issue belongs to the Section Cardiology)

Periodontitis and Systemic Health: Exploring the Oral-Systemic Connection

edited by

Yiorgos Bobetsis

and Phoebus Madianos

submission deadline 20 Mar 2026 | Viewed by 102 | Submission Open

Keywords: periodontal disease; systemic diseases; cardiovascular disease; diabetes mellitus; adverse pregnancy outcomes; respiratory disease; neurodegenerative disorders; obesity; respiratory diseases; chronic kidney disease

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Bladder Cancer: Diagnosis and Treatments

edited by

Stanislav Źiaran

submission deadline 20 Mar 2026 | Viewed by 101 | Submission Open

Keywords: bladder cancer; urothelial cancer; radical cystectomy; targeted therapy; immunotherapy; non-muscle -invasive; muscle-invasive; chemotherapy

(This special issue belongs to the Section Nephrology & Urology)

Clinical Challenges and Future Directions of Interstitial Lung Disease

edited by

Yoshiaki Zaizen

submission deadline 20 Mar 2026 | Viewed by 99 | Submission Open

Keywords: interstitial lung disease; progressive pulmonary fibrosis; early detection; clinical diagnosis; multidisciplinary discussion; treatment; non-pharmacological therapy; end-of-life care; patient-centered management

(This special issue belongs to the Section Respiratory Medicine)

Atrial Fibrillation: Screening, Management and Outcomes

edited by Ahmed AlTurki and Vidal Essebag

submission deadline 20 Mar 2026 | Viewed by 98 | Submission Open

Keywords: atrial fibrillation; ablation; pulmonary vein isolation; atrial fibrillation screening; wearable devices; anti-arrhythmic drugs; cardiovascular outcomes; subclinical atrial fibrillation

(This special issue belongs to the Section Cardiology)

Advances in Diagnosis and Treatment of Endometriosis

edited by

Arrigo Fruscalzo

and

Anis Feki

submission deadline 20 Mar 2026 | Viewed by 96 | Submission Open

Keywords: endometriosis; adenomyosis; diagnosis; classification; therapy; progesterone

(This special issue belongs to the Section Obstetrics & Gynecology)

Exercise and Chronic Pain

edited by Nuria Marín-Jiménez and Milkana Borges-Cosic

submission deadline 20 Mar 2026 | Viewed by 92 | Submission Open

Keywords: chronic pain; exercise therapy; physical activity; fitness; pain management; quality of life; non-pharmacological interventions

(This special issue belongs to the Section Sports Medicine)

Clinical Advances in Maternal–Fetal Medicine: 2nd Edition

edited by

Erich Cosmi

submission deadline 20 Mar 2026 | Viewed by 90 | Submission Open

Keywords: precision medicine; omics; clinical; fetus; Doppler

(This special issue belongs to the Section Obstetrics & Gynecology)

Clinical Advances in Laryngeal Cancer

edited by

Gunnar Wichmann

and

Theresa Wald

submission deadline 20 Mar 2026 | Viewed by 86 | Submission Open

Keywords: head and neck cancer (HNC); laryngeal cancer; larynx organ preservation; immuno-oncology; biomarker; prognostic factor; genetic risk factors; outcome research

(This special issue belongs to the Section Otolaryngology)

Acute Cardiovascular Care in Cardio-Oncology: Present Challenges and Future Pathways

edited by

Raffaele Bugiardini

and Maria Bergami

submission deadline 20 Mar 2026 | Viewed by 86 | Submission Open

Keywords: cardiotoxicity; cardio-oncology; acute cardiovascular care; acute cardiovascular complications; disparities in care

(This special issue belongs to the Section Cardiovascular Medicine)

Minimally Invasive Thoracic Surgery: State of the Art and Future Perspectives

edited by Dustin M. Walters

submission deadline 20 Mar 2026 | Viewed by 83 | Submission Open

Keywords: thoracic surgery; perioperative outcomes; lung cancer resection; minimally invasive surgery; robotic thoracic surgery

(This special issue belongs to the Section Respiratory Medicine)

Current Challenges in Oral Surgery and Pathology

edited by

Christian Bacci

submission deadline 20 Mar 2026 | Viewed by 81 | Submission Open

Keywords: oral medicine; oral pathology; oral surgery; ONJ; MRONJ; BRONJ; laser

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Emerging Insights into Glaucoma, Cataracts, and Refractive Surgery

edited by

Michele Lanza

submission deadline 20 Mar 2026 | Viewed by 76 | Submission Open

Keywords: trabeculoplasty; MIGS; MIBS; trabeculectomy; IOL; biometry; phacoemulsification; femto-cataract; refractive cataract; excimer laser; PRK; femto; LASIK; SMILE; aberrometry; tomography

(This special issue belongs to the Section Ophthalmology)

Intracranial Aneurysms: What Do We Know So Far?

edited by Alessio Albanese and Giuseppe Esposito

submission deadline 20 Mar 2026 | Viewed by 75 | Submission Open

Keywords: intracranial aneurysms; clipping; endovascular therapy; stenting; coiling; cerebral vasospasm; cerebrovascular diseases; microneurosurgery; subarachnoid hemorrhage; bypass

(This special issue belongs to the Section Clinical Neurology)

Emerging Research in Cancer Survivorship

edited by

Elham Mohebbi

submission deadline 20 Mar 2026 | Viewed by 74 | Submission Open

Keywords: cancer survivorship; clinical epidemiology; quality of life; health system; sexual health; mental health; comorbidities; pain management; tobacco cessation; alcohol abstinence; diet

(This special issue belongs to the Section Epidemiology & Public Health)

Bridging Bench, Bedside, and Beyond: Clinical and Translational Strategies for Pregnancy Complications

edited by

Thenral Socrates

and Federica Piani

submission deadline 20 Mar 2026 | Viewed by 72 | Submission Open

Keywords: high-risk pregnancy; cardiovascular complications; cardiometabolic complications; gestational diabetes; pregnancy complications; preeclampsia; hypertension; vascular disorders; endothelial dysfunction; clinical prediction; antenatal diagnosis; personalized treatment

(This special issue belongs to the Section Obstetrics & Gynecology)

Updates in the Use of Pharmacogenetics in Clinical Practice

edited by Rocío Morón Romero and Xando Díaz-Villamarín

submission deadline 20 Mar 2026 | Viewed by 63 | Submission Open

Keywords: pharmacogenetics; personalized medicine; clinical implementation; drug response; pharmacogenomics; precision medicine; healthcare integration; decision support; clinical implications of genetic testing

(This special issue belongs to the Section Pharmacology)

Current Paradigms in Pulmonary Vascular Disease: Past, Present and Future

edited by Parth M. Rali

submission deadline 20 Mar 2026 | Viewed by 62 | Submission Open

Keywords: pulmonary hypertension (PH); pulmonary embolism (PE); rare pulmonary vascular disorders; novel therapeutics; di-agnostic innovations

(This special issue belongs to the Section Respiratory Medicine)

Advancements and Challenges in Retina Surgery: Second Edition

edited by Joaquín Marticorena and

Javier Zarranz-Ventura

submission deadline 20 Mar 2026 | Viewed by 60 | Submission Open

Keywords: retina; vitreoretinal diseases; vitreotomes; optical coherence tomography; vitreoretinal surgery

(This special issue belongs to the Section Ophthalmology)

Displaying special issue 901-950 on page 19 of 31.

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