Molecular Crosstalk in Stress-Induced Psychopathology
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: 31 December 2025 | Viewed by 9
Special Issue Editors
Interests: psychoneuroendocrineimmunology; psychopathology; stress; fibromyalgia; nutrition
2. Research and Clinical Center for Neuropsychiatry of Moscow Healthcare Department, 115419 Moscow, Russia
Interests: adaptation; Alzheimer animal models; apoptosis; behaviour; biomarkers; cellular models; cerebral ischemia; dementia; depression; epilepsy; excitotoxicity; free radicals; glia; glucocorticoid signalin
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Since the pioneering work of Hans Selye, the human stress response has been recognized as an adaptive mechanism essential for survival. Nonetheless, mounting evidence indicates that early-life adversity and chronic psychosocial stress represent significant risk factors for the onset of various mental disorders, including depression, anxiety, eating disorders, substance abuse and neurodegenerative diseases, e.g., Alzheimer’s and Parkinson’s disease. The framework of psychoneuroendocrineimmunology (PNEI) offers a comprehensive network-based model to interpret the intricate bidirectional communication among key biological systems. This includes interactions between hormones, neurotransmitters, cytokines, across the blood-brain barrier and microbiota-derived metabolites, all of which are modulated by stress and may contribute to psychopathological outcomes.
The primary objective of this Special Issue is to advance current understanding of the molecular mechanisms underlying these complex inter-system interactions in the pathogenesis of mental disorders and brain pathology. We welcome contributions focused on molecular-level investigations, including preclinical studies, clinical trials, intervention research, narrative, or systematic reviews, as well as theoretical mathematical models of interactions.
Dr. Ilaria Demori
Prof. Dr. Natalia V. Gulyaeva
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- Depression
- Anxiety
- Post-traumatic stress disorder
- Early life stress
- Microbiota–gut–brain axis
- Blood–brain barrier
- Neurotransmission
- Neuroinflammation
- Eating disorders
- Addiction
- Psychoneuroendocrineimmunology
- Allostasis
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.