International Journal of Molecular Sciences

Molecular and Cellular Basis of Chronic Pain

edited by

submission deadline 31 Dec 2026 | Viewed by 11 | Submission Open

Keywords: neuro– immune crosstalk; chondroprotection; subchondral bone remodeling; central sensitization; nociceptive signaling pathways; health supplements

(This special issue belongs to the Section Molecular Neurobiology)

Updates on Pathogenesis and Molecular Targets of Alzheimer’s Disease

edited by Jean-Pierre Brion and Kunie Ando

submission deadline 31 Dec 2026 | Viewed by 8 | Submission Open

Keywords: Alzheimer’ s disease; tau; amyloid; neurodegenerative diseases; inflammation; biomarkers; genetic variants; risk factors; protein-protein interactions; post-translational modifications

(This special issue belongs to the Section Molecular Neurobiology)

Recent Advances in Optoelectronic Materials

edited by Muhammad Umair Shahid

submission deadline 31 Dec 2026 | Viewed by 7 | Submission Open

Keywords: organic solar cells; DSSCs; perovskite solar cells; donor– acceptor systems; optoelectronic devices; charge separation; sensors; quantum dots; 2D materials; machine learning in materials science

(This special issue belongs to the Section Materials Science)

Cellular and Molecular Mechanisms of Exercise-Induced Tissue Adaptation in Health, Disease and Performance

edited by

Gilberto E. Shiguemoto

and

Wladimir Rafael Beck

submission deadline 31 Dec 2026 | Viewed by 4 | Submission Open

Keywords: skeletal muscle plasticity; exerkines and tissue crosstalk; molecular signaling pathways; exercise training adaptation; mitochondrial function; mitokines and metabolic crosstalk; epigenetic regulation; myokines

(This special issue belongs to the Section Molecular Biology)

Fluorescent Probes for Cellular and Molecular Imaging

edited by

Ritika Gupta

submission deadline 31 Dec 2026 | Viewed by 1 | Submission Open

Keywords: fluorescent probes; molecular imaging; cellular imaging; live-cell imaging; biosensing; aptamer-based probes; antibody conjugates; super-resolution microscopy; biomarker detection; multiplex imaging; optical imaging

(This special issue belongs to the Section Molecular Biology)

Research Progress on Cancer Biomarkers and Molecular Targets

edited by

José Vargas

submission deadline 31 Dec 2026 | Submission Open

Keywords: cancer biomarkers; molecular targets; cellular senescence; autophagy; epigenetics; prognosis; tumor microenvironment; therapy resistance; precision medicine

(This special issue belongs to the Section Molecular Oncology)

Cancer-Driving Molecules: From Molecular Mechanisms to Novel Therapeutics

edited by

Georgios Pantouris

submission deadline 29 Jan 2027 | 8 articles | Viewed by 9615 | Submission Open

Keywords: cancer; mechanism of action; tumor microenvironment; immune system; DNA/RNA/protein; small-molecule probes; activation/inhibition; biological activity

(This special issue belongs to the Section Molecular Oncology)

Emerging Trends of Biotechnology in Bioremediation and Biodegradation

edited by

Marta Alejandra Polti

submission deadline 29 Jan 2027 | 1 articles | Viewed by 2237 | Submission Open

Keywords: emerging technologies; biological treatment; environmental sustainability; innovative methodologies; ecosystem restoration

(This special issue belongs to the Section Molecular Biology)

Molecular Mechanisms of Hypertension

edited by Pedro A. José

submission deadline 29 Jan 2027 | 1 articles | Viewed by 1664 | Submission Open

Keywords: salt sensitivity; inverse salt sensitivity; epigenetics; genetics; organ-to-organ communication

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Mitochondrial Signaling Pathways in Inflammation and Diseases

edited by

Francesca Oppedisano

and

Cristina Algieri

submission deadline 29 Jan 2027 | Viewed by 369 | Submission Open

Keywords: mitochondria; cell metabolism; inflammatory mitochondrial signalling; metabolic pathways; mitochondrial dysfunction; mtDNA; cGAS-STING pathway; NLRP3 inflammasome; human pathology

(This special issue belongs to the Section Biochemistry)

Emerging Metabolomics Techniques and Applications

edited by Jun Han

submission deadline 29 Jan 2027 | Viewed by 210 | Submission Open

Keywords: metabolomics; lipidomics; bioinformatics; micro-extraction; chemical derivatization; liquid chromatography-mass spectrometry (LC-MS); matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS); gas chromatography-mass spectrometry (GC-MS); metabolic profiling; biomarker assay

(This special issue belongs to the Section Molecular Informatics)

Plant Genome Editing: Recent Advances and Future Perspectives

edited by

Hakim Manghwar

submission deadline 29 Jan 2027 | Viewed by 190 | Submission Open

Keywords: gene knockout; gene knock-in; gene knockdown; base editing; transcription activation; prime editing; off-target analysis; new CRISPR variants; high-throughput genome editing system

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Mechanisms of Plant Nutrient Uptake and Signaling Networks

edited by

Tarek Alshaal

submission deadline 29 Jan 2027 | Viewed by 124 | Submission Open

Keywords: rhizosphere interactions; ion homeostasis; transporter regulation; signal transduction; transcriptional control; nutrient use efficiency; root architecture; plant– microbe symbiosis; abiotic stress adaptation; omics integration

(This special issue belongs to the Section Molecular Plant Sciences)

Extracellular Vesicles in Tumor Growth and Progression

edited by

Josiah Ochieng

submission deadline 30 Jan 2027 | Viewed by 96 | Submission Open

Keywords: extracellular vesicles (EVs); tumor cells; secretion and uptake; metastasis; cancer biomarkers

(This special issue belongs to the Section Molecular Oncology)

Targeting Cancer Metabolism: From Mechanism to Therapies

edited by

Zisis Kozlakidis

submission deadline 31 Jan 2027 | 2 articles | Viewed by 3211 | Submission Open

Keywords: cancer metabolism; metabolic alterations; Warburg effect; metabolic reprogramming; metabolic disorder; mitochondrial dysfunction; mitochondrial dynamics

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanisms and Treatment in Gastrointestinal Cancers

edited by

Dani Ran Castillo

submission deadline 31 Jan 2027 | 1 articles | Viewed by 2576 | Submission Open

Keywords: gastrointestinal cancers; tumor microenvironment; immune regulation; biomarkers; therapeutic resistance; liquid biopsy; targeted therapy; immune checkpoint inhibitors; epigenetic regulation

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Novel Biomarkers and Treatment Strategies for Parkinson’s Disease

edited by Aron Emmi

submission deadline 31 Jan 2027 | 2 articles | Viewed by 2290 | Submission Open

Keywords: Parkinson’ s Disease; alpha-synuclein; disease-modifying therapy; biomarkers

(This special issue belongs to the Section Molecular Neurobiology)

Advances in Neurorepair and Regeneration

edited by

Andrei Gresita

and Tiago Santos

submission deadline 31 Jan 2027 | 1 articles | Viewed by 2018 | Submission Open

Keywords: neurorepair; regeneration; neuroplasticity; cellular reprogramming; biomaterials; stroke; spinal cord injury; traumatic brain injury; neurodegenerative diseases

(This special issue belongs to the Section Molecular Neurobiology)

Anticancer, Anti-Inflammatory and Antioxidant Properties of Active Substance and Natural Products

edited by Emira D’Amico

submission deadline 31 Jan 2027 | 3 articles | Viewed by 1949 | Submission Open

Keywords: anticancer activity; anti-inflammatory activity; oxidative stress; immunomodulation; drug discovery; natural products; active substance; plant extracts; phytochemicals

(This special issue belongs to the Section Molecular Biology)

Analysis on Effector and Regulatory Molecules in Renal Diseases

edited by

Takashi Oda

submission deadline 31 Jan 2027 | 2 articles | Viewed by 1830 | Submission Open

Keywords: effector molecules; regulatory molecules; membrane attack complex (MAC); perforin; granzyme; immune complex; neutrophil extracellular traps (NETs); proteolytic enzymes; reactive oxygen species; infection-related glomerulonephritis (IRGN); nephritis-associated plasmin receptor (NAPlr); streptococcal pyrogenic exotoxin B (SPEB); adhesion molecules

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

DNA, Chromatin and Genome Structure

edited by Myakishev-Rempel Max and

Alexandre Vetcher

submission deadline 31 Jan 2027 | 2 articles | Viewed by 1824 | Submission Open

Keywords: DNA structure and dynamics; non-B DNA structures (G-quadruplexes; Z-DNA); DNA topology; R-loops; RNA-DNA triplexes; extrachromosomal DNA (eccDNA); chromatin conformation (Hi-C; Micro-C; 3C); chromatin compaction; TADs and chromatin loops; three-dimensional genome organization; transcription regulation; gene regulation; DNA replication; DNA repair; transposable elements; chromosomal rearrangements; epigenetics; molecular modeling of DNA; molecular modeling of DNA hydration; molecular modeling of chromatin; telomeres; centromeres; introns; noncoding DNA

(This special issue belongs to the Section Molecular Biology)

Molecular Perspective on Skeletal Muscle Regeneration

edited by Xuhui Liu

submission deadline 31 Jan 2027 | 1 articles | Viewed by 1552 | Submission Open

Keywords: skeletal muscle regeneration; satellite cells; stem cell niche; fibro/adipogenic progenitors; aging; muscle stem cells; cell– cell interactions; fibrosis and fatty infiltration; translational therapeutics

(This special issue belongs to the Section Molecular Biology)

Molecular Crosstalk in Allergy, Barrier Dysfunction, and Asthma

edited by

Elisa Boni

submission deadline 31 Jan 2027 | 2 articles | Viewed by 1545 | Submission Open

Keywords: barrier dysfunction; asthma; allergy; molecular pathways; molecular crosstalks

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

The Role of Transcription Factors in Antioxidant Pathways

edited by

Eleonora Stanca

submission deadline 31 Jan 2027 | 1 articles | Viewed by 1463 | Submission Open

Keywords: transcription factor; oxidative stress; NRF1/2; NRF3; NFkB; P53; antioxidant-response elements; neurologial diseases; metabolic diseases; cancer

(This special issue belongs to the Section Molecular Biology)

Targeted Molecular Radio-Immuno-Theranostics: From Cancer to Other Human Diseases—in Honor of Prof. Dr. Otmar Dieter Wiestler

edited by Michael Philipp Bachmann and Holger Stephan

submission deadline 31 Jan 2027 | 2 articles | Viewed by 1079 | Submission Open

Keywords: molecular diagnostics; radiotherapy; immunotherapy; endoradionuclide therapy; radiodiagnostics; radio-immuno-theranostics; radionuclides; PET/SPECT imaging; nanomaterials; chelators; chimeric antigen receptors (CARs); adapter CAR T cells

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Emerging Topics in Polymeric Nanoparticles

edited by

Andrei Honciuc

and

Mirela Honciuc

submission deadline 31 Jan 2027 | 1 articles | Viewed by 687 | Submission Open

Keywords: polymeric nanoparticles; nanostructured materials; functional polymers; Janus particles; self-assembly; drug delivery; environmental remediation; microplastics; biodegradability; nanomedicine; green synthesis; adsorbents; life cycle assessment; surface functionalization; smart materials; biocompatibility; environmental impact; bioaccumulation; responsive polymers; hybrid nanomaterials

(This special issue belongs to the Section Macromolecules)

Current Molecular Advances in Apoptosis

edited by

Mariarosaria Boccellino

and

Davide Viggiano

submission deadline 31 Jan 2027 | Viewed by 527 | Submission Open

Keywords: apoptosis; glomerulonephritis; aging; caspase; endonuclease; DNA; cytokeratin

(This special issue belongs to the Section Biochemistry)

Molecular Insights into Agricultural Hydrology: Plant-Soil-Water Interactions

edited by

Muhammad Bilal Khan

submission deadline 31 Jan 2027 | Viewed by 488 | Submission Open

Keywords: soil– plant– water system; agricultural hydrology; water-use efficiency; root water uptake; rhizosphere interactions; biogeochemical cycling; ecosystem functioning; climate change impacts; wastewater treatment

(This special issue belongs to the Section Molecular Plant Sciences)

Nanoparticles in Nanobiotechnology and Nanomedicine: 3rd Edition

edited by

Costica Caizer

submission deadline 31 Jan 2027 | Viewed by 403 | Submission Open

Keywords: nanoparticles; properties of nanoparticles; methods of obtaining nanoparticles; characterization techniques; theoretical models; computational simulation; applications in nanomedicine; applications in nanobiotechnology

(This special issue belongs to the Section Molecular Nanoscience)

Cancer, Chronic Disease and Health Equity: Translational Oncology in the Era of Multimorbidity and Systems Innovation

edited by

Giorgio Malpeli

, Kiven Erique Lukong and Marco Feligioni

submission deadline 31 Jan 2027 | Viewed by 401 | Submission Open

Keywords: molecular mechanisms in chronic diseases and cancer; cancer metabolism; inflammation; and systemic disease interactions; biomarker discovery in cancer and chronic diseases; biological mechanisms in cancer and chronic diseases; neuroimmune responses in cancer and chronic diseases; epigenetic events in cancer and chronic diseases; translational oncology and precision medicine; artificial intelligence and digital innovation in oncology and chronic disease care; cancer and cardiometabolic disease intersections; multimorbidity management strategies in oncology care; integrated screening; prevention; and survivorship models; implementation science in cancer and chronic disease care

(This special issue belongs to the Section Molecular Oncology)

mRNA Vaccines Against Viral Infectious Diseases: Progress and Prospects

edited by

Barbara Ridolfi

and Maria Teresa Maggiorella

submission deadline 31 Jan 2027 | Viewed by 387 | Submission Open

Keywords: viruses; mRNA vaccines; mRNA structure; mRNA platform technologies; lipid nanoparticle (LNP) delivery; immunization strategies; adjuvants; preclinical trials; clinical trials; germline-targeting; broadly neutralizing antibodies; humoral immune response; cellular immune response; host– vaccine interactions

(This special issue belongs to the Section Molecular Microbiology)

New Insight into Biomaterials for Tissue Engineering and Regenerative Medicine

edited by

Diana Torge

submission deadline 31 Jan 2027 | Viewed by 373 | Submission Open

Keywords: biomaterials; tissue regeneration; regenerative medicine; bone regeneration; periodontal disease; morphology; tissue engineering

(This special issue belongs to the Section Molecular Biology)

Novel Therapeutic Strategies and Targets in Rheumatoid Arthritis

edited by David Fox and

James J. Moon

submission deadline 31 Jan 2027 | Viewed by 341 | Submission Open

Keywords: RA; synovium; FLS; synovial fluid; microbiome; autoimmunity; DMARD; joint inflammation; joint damage; nanoparticle

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Biomedical Applications of Mesenchymal Stem Cells, 2nd Edition

edited by

Giuliana Mannino

and

Debora Lo Furno

submission deadline 31 Jan 2027 | Viewed by 329 | Submission Open

Keywords: mesenchymal stem cells; cell differentiation; cell therapy; regenerative medicine; tissue homeostasis; disease; cartilage

(This special issue belongs to the Section Molecular Biology)

Cryo-EM and Cryo-Tomography in Macromolecular Structure Analysis

edited by

R. Holland Cheng

submission deadline 31 Jan 2027 | Viewed by 299 | Submission Open

Keywords: macromolecular structure; precision nanomedicine; cryo-electron microscopy (cryo-EM); cryo-electron tomography (cryo-ET); viral capsids; AI/ML in structural analysis; time-resolved imaging; nanoparticle delivery; in-cell tomography; structural dynamics; molecular mechanisms; protein complexes; membrane proteins; macromolecular assemblies; conformational changes; integrative structural biology; cellular structural biology; drug delivery systems; therapeutic design

(This special issue belongs to the Section Macromolecules)

Biomaterials: From Design, Synthesis and Characterization to Application—2nd Edition

edited by

Tao Sun

and

Xujin Bao

submission deadline 31 Jan 2027 | Viewed by 298 | Submission Open

Keywords: biomaterials; synthesis; characterization; therapeutics; diagnosis

(This special issue belongs to the Section Materials Science)

Nano-Biomaterials for Biomedicine and Tissue Regeneration

edited by

Silvia Barbon

and

Elena Stocco

submission deadline 31 Jan 2027 | Viewed by 287 | Submission Open

Keywords: nanostructured biomaterials; cell-scaffold interactions; drug delivery systems; tissue engineering; regenerative medicine

(This special issue belongs to the Section Molecular Nanoscience)

DNA Damage and Repair Mechanisms in Cancer

edited by

Luigi Alfano

submission deadline 31 Jan 2027 | Viewed by 247 | Submission Open

Keywords: DNA damage response (DDR); genome instability ; synthethic lethality ; DNA repair

(This special issue belongs to the Section Molecular Oncology)

Discovery of Plant-Derived Compounds and Their Immunomodulatory Applications

edited by

Jun Jiang

submission deadline 31 Jan 2027 | Viewed by 227 | Submission Open

Keywords: plant-derived compounds; immunomodulators; phytochemicals; immune signaling; natural products; autoimmune diseases; intestinal flora; in vitro evaluation

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Angiogenesis: Mechanisms and Targets in a Wide Spectrum of Diseases

edited by Lei Phillip Wang

submission deadline 31 Jan 2027 | Viewed by 217 | Submission Open

Keywords: angiogenesis; immune– vascular interactions; cancer; autoimmune disease; neurodegenera-tion; blood– brain barrier; biomarkers; therapeutic targeting

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Biology of Gynecologic Health and Disease

edited by Marcin Bobiński

submission deadline 31 Jan 2027 | Viewed by 217 | Submission Open

Keywords: molecular biomarkers; gynecologic endocrinology; gynecologic oncology; hypothalamic– pituitary– ovarian axis; ovarian reserve and reproductive aging

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Genetics- and Genomics-Based Wheat Improvement and Breeding

edited by Jian Ma

submission deadline 31 Jan 2027 | Viewed by 204 | Submission Open

Keywords: wheat crop; germplasm; genetics; genomics; breeding

(This special issue belongs to the Section Molecular Plant Sciences)

Advanced Molecular Mechanisms, Bioprocessing and Functional Evaluation of Edible Plants: From Bioactive-Ingredient Enhancement to Health-Promoting Applications

edited by Hongxun Tao,

Anna Wai San Cheang

and

Yuxiao Wang

submission deadline 31 Jan 2027 | Viewed by 179 | Submission Open

Keywords: edible plants; plant foods; molecular mechanisms; advanced bioprocessing; bioactive ingredients; functional evaluation; health-promoting applications; structure– function relationship; signal transduction pathways; bioavailability and metabolism; gut microbiota modulation; omics technologies

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Small-Molecule Fluorescent Probes: From Design to Biological Applications

edited by Qinglong Qiao

submission deadline 31 Jan 2027 | Viewed by 172 | Submission Open

Keywords: fluorescent probes; fluorescence imaging; biosensors; molecular design; biological applications

(This special issue belongs to the Section Molecular Biophysics)

Multi-Omics-Driven Advances in Plant Sciences

edited by Sheikh Mansoor

submission deadline 31 Jan 2027 | Viewed by 127 | Submission Open

Keywords: multi-omics; plant genomics; transcriptomics; metabolomics; crop improvement; abiotic and biotic stress tolerance; plant– microbe interactions; functional genomics

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Therapeutic Strategies for Intrahepatic Cholangiocarcinoma

edited by

Worachart Lert-Itthiporn

submission deadline 31 Jan 2027 | Viewed by 105 | Submission Open

Keywords: intrahepatic cholangiocarcinoma; molecular therapy; targeted therapy; immunotherapy; biomarkers; tumor microenvironment; genomic alterations; liquid biopsy; resistance mechanisms; precision oncology

(This special issue belongs to the Section Molecular Oncology)

Research on Plant-Growth-Promoting Rhizobacteria

edited by

Dragana Miljaković

submission deadline 31 Jan 2027 | Viewed by 67 | Submission Open

Keywords: plant growth promoting rhizobacteria; plant– microbe interactions; microbiome-based selection; microbiome engineering; synthetic communities; biofertilization; biocontrol; stress tolerance; smart delivery methods

(This special issue belongs to the Section Molecular Microbiology)

Current Research on the Molecular and Cellular Mechanisms of Cancer

edited by Seungbaek Lee

submission deadline 31 Jan 2027 | Viewed by 25 | Submission Open

Keywords: cancer biology; molecular oncology; tumor microenvironment; therapeutic resistance; precision oncology

(This special issue belongs to the Section Molecular Biology)

Kidney Diseases: Molecular Mechanisms and Therapies

edited by

George J. Dugbartey

submission deadline 31 Jan 2027 | Submission Open

Keywords: kidney diseases; pathophysiology; molecular mechanisms; therapeutic targets; acute kidney injury; chronic kidney disease; polycystic kidney disease; end-stage renal disease; IgA nephropathy; diabetic nephropathy; hypertensive nephropathy; renal cancer; kidney infarction; kidney infection; kidney failure; kidney stones; renal tubular acidosis; renal artery stenosis; acute tubular necrosis; glomerulopathy; interstitial nephritis; nephrotic syndrome; simple kidney cyst

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Hydrogel Materials for Regenerative Medicine: Molecular Perspectives

edited by

Yiran Li

submission deadline 31 Jan 2027 | Submission Open

Keywords: supramolecular hydrogels; adaptive materials; biomimetic material; stimuli-responsive hydrogels; tissue engineering; regenerative medicine; phase separation hydrogel

(This special issue belongs to the Section Materials Science)

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