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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Molecular Research on Actinomycetes-Derived Natural Products

edited by Fong Tian Wong

submission deadline 30 Apr 2025 | Viewed by 8 | Submission Open

Keywords: actinomycetes; natural products; actinobacterial; genome mining; omics; secondary metabolites; genetic engineering; discovery; structural diversity

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Design of Artificial Receptors Using Virtual Approaches

edited by Houjin Zhang

submission deadline 30 Apr 2025 | Viewed by 6 | Submission Open

Keywords: artificial receptors; protein design; computational biology; drug targeting; biosensors; tissue engineering; synthetic biology

(This special issue belongs to the Section Molecular Biophysics)

Mitochondrial Remodeling and the Targeting Strategies for Disease Treatment

edited by

Yong Teng

submission deadline 1 May 2025 | 6 articles | Viewed by 14620 | Submission Open

Keywords: structural and functional mitochondrial remodeling; mitochondrial turnover accomplished by mitophagy and biogenesis; proteomic alterations and posttranslational modifications mediated by mitochondrial remodeling; mitochondrial remodeling-mediated metabolic alterations; retrograde signaling whereby mitochondria modify the nuclear program; mitochondrial dynamism; fitness; biogenesis interactome; novel strategies for targeting mitochondrial remodeling; treatment of mitochondria-associated human diseases

(This special issue belongs to the Section Molecular Biology)

Molecular Research for Cereal Grain Quality 2.0

edited by

Jinsong Bao

submission deadline 10 May 2025 | 8 articles | Viewed by 11918 | Submission Open

Keywords: cereal; rice; wheat; maize; barley; sorghum; millet; molecular markers; genome-wide association studies; genome editing; genome selection; sequencing; molecular selection; transcriptomics; omics; post-translational regulation; starch; protein; lipids; vitamin; phenolics; processing quality; eating quality

(This special issue belongs to the Section Molecular Plant Sciences)

Fluorescent Nanoparticles Compositions and Their Biomedical Applications

edited by Bonghwan Chon

submission deadline 10 May 2025 | Viewed by 355 | Submission Open

Keywords: fluorescence nanoparticles; biomedical applications; nanomaterials; nanoparticles; bio-imaging; cancer therapy; nanomedicine; optical properties; nanocomposite

(This special issue belongs to the Section Molecular Nanoscience)

Research on Cyclodextrin: Properties and Biomedical Applications

edited by Jug Mario

submission deadline 15 May 2025 | 1 articles | Viewed by 1502 | Submission Open

Keywords: cyclodextrins; cyclodextrin– metal organic framework; cyclodextrin-based polyrotaxane and polycatenane; inclusion complex formation; cholesterol; solubility; chemical stability; bioavailability; drug delivery; modified drug release; gene delivery; wound healing

(This special issue belongs to the Section Materials Science)

Hematological Malignancies: Molecular Mechanisms and Therapy, 2nd Edition

edited by

Stella Bouziana

submission deadline 15 May 2025 | Viewed by 240 | Submission Open

Keywords: hematological malignancies; molecular pathways; genetics; immunopathogenesis; biomarkers; novel therapies

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Biosynthesis and Application of Natural Compound

edited by

Konstantin Volcho

and

Olga Luzina

submission deadline 20 May 2025 | 14 articles | Viewed by 27468 | Submission Open

Keywords: natural compounds; biosynthesis; biotransformation; metabolism; derivatives of natural compounds; medicines/medication; biological activities

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Mitochondrial Genome of Aquatic Animals: Analysis of Structure, Evolution and Diversity

edited by

Yuri Kartavtsev

and

Ui Wook Hwang

submission deadline 20 May 2025 | 12 articles | Viewed by 17805 | Submission Open

Keywords: aquatic animals; genomics; mitogenomes; structure; phylogenetic informativeness; evolution; comparative genomics; diversity; biomarker; function; mitonuclear relations

(This special issue belongs to the Section Molecular Genetics and Genomics)

New Pharmacological Insights on Natural Macromolecules and Natural Small Molecules

edited by

Dong-Sung Lee

submission deadline 20 May 2025 | 7 articles | Viewed by 17223 | Submission Open

Keywords: bioactive natural molecules; natural macromolecules; natural small molecules; drug delivery; inflammatoty diseases; neurodegenerative diseases; skin diseases; cancer; metabolic diseases

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Recent Advances in Molecular Mechanisms of Human Papillomavirus Family (HPV) Induced Oncogenesis

edited by

Subhasis B. Biswas

submission deadline 20 May 2025 | 8 articles | Viewed by 16391 | Submission Open

Keywords: human papillomavirus (HPV); oncogenesis; mechanism; diagnosis; classification; etiology; pathophysiology; biochemistry; genetics; molecular biology; epidemiology; cervical cancer; oropharyngeal cancer; oncology

(This special issue belongs to the Section Molecular Oncology)

Pathogenesis and Treatments of Head and Neck Cancer

edited by

Marko Tarle

submission deadline 20 May 2025 | 7 articles | Viewed by 15233 | Submission Open

Keywords: HNSCC; premalignant changes; tumor microenvironment; molecular biomarkers; targeted therapy; oral tumorigenesis; molecular pathogenesis; tumor biology; tumor immunology

(This special issue belongs to the Section Molecular Oncology)

Blast-Induced Neurotrauma: Molecular Mechanisms Supported by Comparative Experimental and Clinical Findings

edited by

Ibolja Cernak

submission deadline 20 May 2025 | 6 articles | Viewed by 14764 | Submission Open

Keywords: blast injuries; blast-induced neurotrauma; experimental research; experimental models; clinical research; molecular mechanisms; biomarkers; imaging; neurological deficits; treatment

(This special issue belongs to the Section Molecular Neurobiology)

Health Promoting Benefits of Natural Products and Functional Foods

edited by

Andrea Zangara

and

Emad Al-Dujaili

submission deadline 20 May 2025 | 8 articles | Viewed by 14762 | Submission Open

Keywords: natural products; functional foods; health promotion; nutrigenomics; evidence-based preventive healthcare; phytochemicals; biomarkers; chronic diseases

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Bioactive Lipids: From the Perspective of Cellular and Molecular Mechanisms

edited by

Igor Manzhulo

and

Anna A. Tyrtyshnaia

submission deadline 20 May 2025 | 6 articles | Viewed by 14001 | Submission Open

Keywords: lipids; polyunsaturated fatty acids; lipid metabolism; lipid mediators; inflammation; neuroprotection

(This special issue belongs to the Section Bioactives and Nutraceuticals)

The Potential Roles of Natural Active Products in Neurological Disorders

edited by Anna D. Serefko

submission deadline 20 May 2025 | 3 articles | Viewed by 12113 | Submission Open

Keywords: natural active products; phytochemicals; bioactive compounds; Neurological Disorders; depressive disorders; Parkinson's disease; depressive/epileptic episodes; antidepressants and antiepileptics; Alzheimer's disease; brain stroke; molecular mechanism; drug delivery; therapeutic potentials; structure-activity relationships; advanced therapies

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Mechanism of Enzyme Catalysis: When Structure Meets Function

edited by Ivana Leščić Ašler

submission deadline 20 May 2025 | 9 articles | Viewed by 11886 | Submission Open

Keywords: three-dimensional structure of enzymes; enzyme stability; solubility and flexibility; structure-function relationship in enzymes; mechanism of enzyme catalysis; enzyme kinetics; substrate specificity of enzymes; regulation of enzyme activity; enzyme engineering

(This special issue belongs to the Section Biochemistry)

Advances in the Prevention and Treatment of Ischemic Diseases

edited by

Egor Yu. Plotnikov

submission deadline 20 May 2025 | 6 articles | Viewed by 11409 | Submission Open

Keywords: stroke; acute kidney injury; dietary approaches; liver ischemia; heart attack; stem cells; hypoxia; preconditioning; antioxidants

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Advances in New Combination Therapies for Cancer

edited by Valeria Lucarini and

Camilla Palumbo

submission deadline 20 May 2025 | 6 articles | Viewed by 11391 | Submission Open

Keywords: immunotherapy; target therapy; chemotherapy; tumor microenvironment; combination therapies; preclinical models

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advanced Research on Immune Response to Viral Infection

edited by Tatiana Betáková

submission deadline 20 May 2025 | 5 articles | Viewed by 11005 | Submission Open

Keywords: virus; infection; immunity; signaling pathways; cytokine; antibody; pathology

(This special issue belongs to the Section Molecular Immunology)

Cancer Biology: From Genetic Aspects to Treatment

edited by

Silvia Cantara

submission deadline 20 May 2025 | 9 articles | Viewed by 10803 | Submission Open

Keywords: cancer biology; cancer biomarker; cancer progression; cancer metastasis; genetic of cancer

(This special issue belongs to the Section Molecular Oncology)

Advances in Therapeutics against Eukaryotic Pathogens

edited by

Edward D’Antonio

submission deadline 20 May 2025 | 6 articles | Viewed by 10773 | Submission Open

Keywords: medicinal chemistry; parasitology; pathogen; drug-target; NTD; cryptosporidia; Giardia; helminths; Leishmania; Naegleria; Plasmodium; Schistosoma; Toxoplasma; Trichomonas; Trypanosoma

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Biomimetic Materials Applied in the Analytical and Biomedical Fields

edited by

Iacob Bogdan-Cezar

and

Ede Bodoki

submission deadline 20 May 2025 | 5 articles | Viewed by 10611 | Submission Open

Keywords: biomimetics; molecular recognition; imprinted polymers; smart materials; molecular complexes; polymeric biomaterials; biomedical materials; analytical methods; molecular interactions; artificial receptors

(This special issue belongs to the Section Materials Science)

Viral and Host Targets to Fight RNA Viruses

edited by

Tommaso Felicetti

submission deadline 20 May 2025 | 5 articles | Viewed by 10278 | Submission Open

Keywords: RNA viruses; antiviral agents; medicinal chemistry; direct-acting antivirals; host-targeting agents; drug design

(This special issue belongs to the Section Molecular Genetics and Genomics)

Advances on Retinal Diseases: 2nd Edition

edited by Minzhong Yu

submission deadline 20 May 2025 | 6 articles | Viewed by 10087 | Submission Open

Keywords: retina; optic nerve; ocular disorder; retinal disease; genetic mutation; aging; drug side effects; novel mutations/biomarkers; signaling pathways; spectral domain optical coherence tomography; stem cell; gene therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Short and Long-Term Profound Acid Inhibition: Indications and Concerns

edited by

Helge L. Waldum

submission deadline 20 May 2025 | 3 articles | Viewed by 9921 | Submission Open

Keywords: gastric acid; gastric cancer; gastric neuroendocrine tumours; gastric juice; gastrin; Helicobacter pylori; oesophageal reflux disease; pepsin; peptic ulcer disease; gastric cancer histology and classification; rebound acid hypersecretion

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Bacteriophages Biology and Bacteriophage-Derived Technologies

edited by Wilfried Moreira

submission deadline 20 May 2025 | 5 articles | Viewed by 9906 | Submission Open

Keywords: bacteriophage; antibiotic resistance; biofilm; molecular biology; genetic engineering; synthetic biology

(This special issue belongs to the Section Biochemistry)

Immunity in Neurodegenerative Diseases: Systemic Immune Imbalance, Neuroinflammation, and Beyond

edited by

Ivana Munitic

and

Frenkel Dan

submission deadline 20 May 2025 | 7 articles | Viewed by 9840 | Submission Open

Keywords: neurodegeneration; CNS immunosurveillance; neuroinflammation; neuro-immune axis; glia; T cells; phagocytosis; immunomodulation; autoimmunity; immunodeficiency

(This special issue belongs to the Section Molecular Neurobiology)

Focus on Antioxidants and COVID-19

edited by

Marija S. Plješa-Ercegovac

submission deadline 20 May 2025 | 4 articles | Viewed by 9520 | Submission Open

Keywords: antioxidants; COVID-19; oxidative stress; antioxidant capacity; long-COVID; vitamins

(This special issue belongs to the Section Biochemistry)

Insights on the Role of Stem Cells in Tendon Tissue Engineering: From Basic Science to Translational Medicine

edited by

Maria Camilla Ciardulli

and

Nicola Maffulli

submission deadline 20 May 2025 | 5 articles | Viewed by 9431 | Submission Open

Keywords: stem cells; tenogenic differentiation; 3D in vitro tendon models; immunomodulation; biomimetic scaffolds; in vivo tendon models; dynamic cultures

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Advances in Liver Fibrosis

edited by

Domenica Mangieri

submission deadline 20 May 2025 | 4 articles | Viewed by 8877 | Submission Open

Keywords: liver fibrosis; inflammation; hypoxia; angiogenesis; hepatic stellate cells; drug therapy; natural compounds; phytochemicals

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Dental Health and Disease: From the Molecular and Pathological Perspectives

edited by

Ancuţa Goriuc

and

Ionut Luchian

submission deadline 20 May 2025 | 9 articles | Viewed by 8858 | Submission Open

Keywords: dental health; oral diseases; molecular mechanisms; pathological mechanisms; treatment perspectives; dentistry; oral medicine; oral pathology; physiopathology in dentistry; periodontal disease; oral fluids

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Immunological and Molecular Networks in the Skin and Skin Diseases

edited by

Ankit Srivastava

submission deadline 20 May 2025 | 3 articles | Viewed by 8707 | Submission Open

Keywords: skin diseases; skin immunology; skin inflammation; skin aging; skin cancers; cytokine/chemokine networks; molecular signaling pathways; non-coding RNAs; targeted therapies

(This special issue belongs to the Section Molecular Immunology)

Molecular Mechanisms Subserving Taste and Olfaction Systems

edited by

Lindsey Schier

submission deadline 20 May 2025 | 7 articles | Viewed by 8615 | Submission Open

Keywords: taste; olfaction; gustation; odor; chemoreception; taste bud cells; nutrient sensing; ingestive behavior; olfactory cilia; olfactory receptor neurons; olfactory bulb; gustatory cortex; piriform cortex; sensory development; food learning; neural plasticity; obesity; eating disorders; appetite

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Progression of Genome-Related Diseases

edited by

Salvatore Saccone

and

Francesco Calì

submission deadline 20 May 2025 | 7 articles | Viewed by 8461 | Submission Open

Keywords: next-generation sequencing; genetic diseases; multifactorial diseases; diagnostic tolls; human health

(This special issue belongs to the Section Molecular Genetics and Genomics)

Structural Dynamics of Macromolecules

edited by

Ki Hyun Nam

submission deadline 20 May 2025 | 4 articles | Viewed by 8327 | Submission Open

Keywords: Structural biology; Structural dynamics; Serial crystallography; X-ray crystallography; Cryo-EM time-resolved studies; Molecular dynamics

(This special issue belongs to the Section Molecular Biophysics)

Genetic Engineering in Microbial Biotechnology

edited by

Fernando Santos-Beneit

submission deadline 20 May 2025 | 7 articles | Viewed by 8190 | Submission Open

Keywords: white biotechnology; red biotechnology; green biotechnology; yellow biotechnology; genetic engineering; microorganisms; bacteria; enzymes; genetics; bioproducts

(This special issue belongs to the Section Molecular Microbiology)

New Drugs Regulating Cytoskeletons in Human Health and Diseases

edited by

Gilles Breuzard

Maxime Robin

and

Hervé Kovacic

submission deadline 20 May 2025 | 5 articles | Viewed by 7834 | Submission Open

Keywords: tubulin; actine; cytoskeletons; associated proteins; pharmacological agent; repurposing of drugs; oncology; neurodegenerative diseases

(This special issue belongs to the Section Molecular Pharmacology)

Molecular Research on Skeletal Muscle Biology

edited by

Atsushi Asakura

submission deadline 20 May 2025 | 6 articles | Viewed by 7775 | Submission Open

Keywords: skeletal muscle; muscular dystrophy; satellite cell; muscle regeneration; myofibrosis; exercise

(This special issue belongs to the Section Molecular Biology)

Advances in Graphene Film and Composites

edited by

Karolina Anna Drogowska-Horná

submission deadline 20 May 2025 | 3 articles | Viewed by 7749 | Submission Open

Keywords: graphene composites; van der Waals heterostructures; graphene– oxide thin-films composites; graphene functionalization

(This special issue belongs to the Section Materials Science)

Influenza Viruses: Infection and Genomics

edited by

Daniele Focosi

submission deadline 20 May 2025 | 5 articles | Viewed by 7636 | Submission Open

Keywords: influenza viruses; avian influenza; virus replication; infection; convergent evolution; restriction factors

(This special issue belongs to the Section Molecular Immunology)

New Horizon for Non-coding RNAs

edited by

Hiroki Sato

submission deadline 20 May 2025 | 5 articles | Viewed by 7393 | Submission Open

Keywords: microRNAs; long noncoding RNAs; circular RNAs; transcriptional control; regulatory networks; function prediction

(This special issue belongs to the Section Molecular Genetics and Genomics)

Melanoma: Molecular Mechanisms and Therapy

edited by

Balázs Margit

submission deadline 20 May 2025 | 6 articles | Viewed by 7373 | Submission Open

Keywords: melanoma progression; melanoma metastasis molecular background; targeted therapy; immunotherapy; acquired drug resistance; prognostic and predictive markers; therapeutic targets

(This special issue belongs to the Section Molecular Oncology)

Advances in Natural Active Products Derived from Foods: Antioxidant, Antinociceptive and Anti-inflammatory Activities

edited by Ettore Novellino

submission deadline 20 May 2025 | 5 articles | Viewed by 7313 | Submission Open

Keywords: antioxidants; bioactive compounds; food-derived products; health benefits; nutraceuticals; inflammation; pain management

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Role of p53 Family in Targeted Therapy of Cancers

edited by

Ignacija Vlasic

and

Neda Slade

submission deadline 20 May 2025 | 3 articles | Viewed by 7253 | Submission Open

Keywords: p53 family of proteins; p53 family isoforms/splice variants; p53 family crosstalk; mutant p53; altered expression of p53 family members/isoforms; cancer progression; targeted therapy; therapy resistance

(This special issue belongs to the Section Molecular Oncology)

Nanoparticles in Nanobiotechnology and Nanomedicine: 2nd Edition

edited by

Costica Caizer

submission deadline 20 May 2025 | 4 articles | Viewed by 7232 | Submission Open

Keywords: nanoparticles; properties of nanoparticles; methods of obtaining nanoparticles; characterization techniques; theoretical models; computational simulation; applications in nanomedicine; applications in nanobiotechnology

(This special issue belongs to the Section Molecular Nanoscience)

Molecular Advances on Insulin Resistance and Metabolic Dysfunction, 2nd Edition

edited by

Melania Manco

and

Amalia Gastaldelli

submission deadline 20 May 2025 | 3 articles | Viewed by 7174 | Submission Open

Keywords: dysregulated fatty acid and/or branched chain amino acids metabolism; metabolic inflexibility; tissue lipid accumulation; lipotoxicity and lipid mediated cell signaling; insulin resistance reversal; cancer development; low-grade inflammation and/or altered expression; synthesis and degradation and bioavailability of IGF binding proteins; environmental chemicals; mechanisms of T3D; microbiota and antimicrobials modulation; endocrine disruptors; altered immune system homeostasis

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

News in Skin Diseases: From Basic Mechanisms to Therapies

edited by

Takemichi Fukasawa

submission deadline 20 May 2025 | 4 articles | Viewed by 7120 | Submission Open

Keywords: skin diseases; psoriasis; atopic dermatitis; scleroderma

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Advances in the Diagnosis and Drug Therapies of Atherosclerotic Cardiovascular Diseases (ASCVD)

edited by

Nikolaos Kadoglou

submission deadline 20 May 2025 | 2 articles | Viewed by 7017 | Submission Open

Keywords: atherosclerotic cardiovascular diseases; gene expression; gene therapy; biomarkers; lipid lowering; hypercholesterolemia; PCSK9; immunomodulators; anti-inflammatory drugs

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Mechanisms of Immune Tolerance and Autoimmune Diseases

edited by

Marcos López Hoyos

and

Jordi Ochando

submission deadline 20 May 2025 | 1 articles | Viewed by 6484 | Submission Open

Keywords: immunological tolerance; autoimmune diseases; autoinflammatory diseases; inflammation; immune-mediated diseases

(This special issue belongs to the Section Molecular Immunology)

Displaying special issue 3101-3150 on page 63 of 74.

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