Wired for Change: Neurotransmitter Plasticity and Circuit Dynamics in Health and Disease
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: 30 November 2025 | Viewed by 26
Special Issue Editor
Special Issue Information
Dear Colleagues,
We invite submissions to the Special Issue Wired for Change: Neurotransmitter Plasticity and Circuit Dynamics in Health and Disease, which will explore how dynamic changes in neurotransmitter identity, signaling, and balance shape neural circuit function and behavior. Neurotransmitter plasticity—including phenotype switching, co-release, and re-specification—plays a critical role in adapting brain function to environmental and developmental stages. Disruptions in these processes can contribute to a wide range of neuropsychiatric and neurodevelopmental disorders.
This Issue welcomes original research and reviews that examine how neurotransmitter dynamics regulate normal behavior or contribute to the etiology of brain diseases such as depression, anxiety, schizophrenia, and neurodegeneration. We are especially interested in studies using innovative molecular, circuit-level, and translational approaches—including imaging, opto/chemogenetics, single-cell transcriptomics, and disease modeling.
Our goal is to foster cross-disciplinary dialogue and highlight mechanisms by which neurotransmitter flexibility influences behavior and mental health.
We look forward to your contributions.
Dr. Alessandra Porcu
Guest Editor
Manuscript Submission Information
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Keywords
- neurotransmitter
- behavioral neuroscience
- neuropsychiatric disorders
- neurological disorders
- neuroplasticity
- neuronal circuit
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