Advanced Research in Alzheimer’s Disease: From Pathology to Therapy
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 30 November 2025 | Viewed by 16
Special Issue Editor
Special Issue Information
Dear Colleagues,
Alzheimer’s disease (AD) is a neurodegenerative disorder without a cure or effective treatment against its progression. Its complex physiopathology, in particular, one of the main issues representing an enormous barrier to developing therapies for treating this disease, which affects millions worldwide. Nowadays, it is known that AD encompasses several alterations in varied diverse pathways (metabolism, immune response, redox defense, neural plasticity, cell survival, among others). However, most AD alterations appear to be interconnected at a certain level. This has motivated scientists to study and develop multifunctional agents and implement mixed therapies capable of exerting multiple beneficial actions in AD patients.
This Special Issue will identify new insights into the molecular aspects of potential therapies against AD, particularly those focused on multiactivity compounds or multiple disease pathways through chemical agents or combined therapeutic strategies. It will expand knowledege of molecular targets in AD pathology as a potential tool in developing treatments against AD. Molecular analysis derived from preclinical in vivo, in vitro and in silico studies of compounds with multifunctional properties against AD are suitable. Studies on novel physiopathological targets and potential molecules that have multiple beneficial actions in AD patients are encouraged. Studies evaluating pharmacological or non-pharmacological mixed therapies are also welcome
Dr. Sofía Yolanda Díaz Miranda
Guest Editor
Manuscript Submission Information
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Keywords
- multifunctional compounds in Alzheimer’s disease therapy
- translational medicine in Alzheimer's disease
- novel drug candidates for Alzheimer's disease
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