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Breast Cancer: From Molecular Mechanism to Therapeutic Strategy

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".

Deadline for manuscript submissions: 10 July 2026 | Viewed by 1

Special Issue Editor


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Guest Editor
Department of Pharmacology, Faculty of Health Sciences, Medical University of Lublin, Lublin, Poland
Interests: cancer; anticancer
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Breast cancer remains one of the most prevalent and challenging malignancies worldwide, characterized by profound heterogeneity in molecular, cellular and clinical features. This Special Issue, titled “Breast Cancer: From Molecular Mechanism to Therapeutic Strategy”, aims to provide a comprehensive overview bridging fundamental insights into breast cancer biology with the development and optimisation of therapeutic approaches.

At the molecular level, recent advances have elucidated key signalling pathways, genetic and epigenetic alterations, tumour microenvironment dynamics, and mechanisms of metastasis and therapy resistance. Understanding these processes is critical for identifying novel biomarkers for diagnosis, prognosis and prediction, and for defining the molecular sub-strata of disease that demand tailored interventions.

On the therapeutic front, this Issue emphasises how these molecular findings inform the design of improved treatment strategies, including targeted therapies, immunotherapies, combination regimens, and approaches addressing resistance mechanisms. Importantly, integration of molecular biomarkers into clinical decision-making and treatment algorithms is a central theme, enabling the move towards precision medicine in breast oncology.

The aim of this Issue is to integrate basic knowledge, translational research, and clinical experience to contribute to the development of more effective, targeted, and safe treatments for breast cancer. Furthermore, it serves as a platform for knowledge exchange between scientists, clinicians, and biotechnologists, supporting the development of innovative therapeutic strategies in the coming years.

I cordially invite you to submit original research articles and review papers on these widely discussed topics.

Dr. Anna Makuch-Kocka
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • breast cancer
  • molecular mechanisms
  • therapeutic strategies
  • tumor microenvironment
  • precision oncology

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Published Papers

This special issue is now open for submission.
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