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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Molecular Insights into the Environmental Toxicity of Contaminants and Risk Mitigation Strategies

edited by

Barbara Mognetti

and

Tiziana Cappello

submission deadline 31 Jul 2025 | 1 articles | Viewed by 745 | Submission Open

Keywords: microplastic toxicity; environmental pollutants; molecular mechanisms; cell metabolic pathways; in vivo; in vitro; and in silico models; pollutant interactions; risk mitigation strategies

(This special issue belongs to the Section Molecular Toxicology)

Selected Papers from the 13th International Conference on Carbonic Anhydrases and Other Research

edited by

Claudiu T. Supuran

and

Óscar López

submission deadline 31 Jul 2025 | 1 articles | Viewed by 697 | Submission Open

Keywords: metalloenzymes; carbonic anhydrase; inhibitors; activators; pharmacology; SLC-0111; anticancer agents

(This special issue belongs to the Section Biochemistry)

Recent Advances in Soybean Molecular Breeding

edited by Dong Cao

submission deadline 31 Jul 2025 | 1 articles | Viewed by 680 | Submission Open

Keywords: soybean; plant architecture; adaptation; yield improvement; molecular breeding; nutritional quality traits; stress tolerance

(This special issue belongs to the Section Molecular Plant Sciences)

Cardiovascular Disease: Molecular Advances on Pathophysiology and Therapies—2nd Edition

edited by

Andrea D'Amato

submission deadline 31 Jul 2025 | 1 articles | Viewed by 619 | Submission Open

Keywords: cardiovascular disease; heart failure; biomarkers; pathophysiology; ischemic heart disease; atherosclerosis; coronary microvascular dysfunction; pharmacology

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Genetic and Genomic Diagnostics for Rare Diseases

edited by

Antonella La Russa

submission deadline 31 Jul 2025 | 1 articles | Viewed by 596 | Submission Open

Keywords: genome sequencing; molecular diagnosis; rare diseases; multi-omics; next-generation sequencing; long-read RNA-Seq

(This special issue belongs to the Section Molecular Genetics and Genomics)

Synthetic Chemistry in Drug Discovery

edited by Kathiravan Suppan

submission deadline 31 Jul 2025 | Viewed by 565 | Submission Open

Keywords: late-stage functionalization; AI-driven synthesis; drug discovery; synthetic chemistry; transition metal catalysis

(This special issue belongs to the Section Molecular Pharmacology)

Current Developments in Glioblastoma Research and Therapy: 2nd Edition

edited by

Aleksandra Majchrzak-Celińska

submission deadline 31 Jul 2025 | 2 articles | Viewed by 553 | Submission Open

Keywords: diagnostic; prognostic and predictive biomarkers of glioblastoma; ways to target glioma stem cells; targeting glioblastoma-related signaling pathways; epigenetics of glioblastoma; treatment resistance mechanisms; novel treatment options for glioblastoma; combinatorial therapies; immunotherapy; nanotherapy; the application of CRISPR/Cas9 in glioma research; molecular testing of long-term glioblastoma survivors

(This special issue belongs to the Section Molecular Neurobiology)

The Impact of Biomolecules on the Pathogenesis of Oral and Periodontal Diseases

edited by

Ujjal Kumar Bhawal

submission deadline 31 Jul 2025 | 1 articles | Viewed by 528 | Submission Open

Keywords: biomolecules; inflammatory mediators; enzymes; cytokines; dysbiosis; microbiome; genetic and epigenetic factors; oral and periodontal diseases

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Research on Advanced Optical Materials 2.0: From Materials to Applications

edited by

Bong-Hyun Jun

and Won Yeop Rho

submission deadline 31 Jul 2025 | 1 articles | Viewed by 481 | Submission Open

Keywords: metal materials; plasmonic materials; SERS substrates; fluorescence materials; dye-doped materials; quantum dots; up-conversion materials; carbon materials; meta materials; bioapplications; energy applications; LED applications; bioimaging; molecules; molecular dynamic simulations; molecular materials

(This special issue belongs to the Section Materials Science)

Inflammatory Bowel Disease: Pathogenesis and Novel Therapeutic Approaches

edited by Francisco Giner

submission deadline 31 Jul 2025 | 1 articles | Viewed by 439 | Submission Open

Keywords: coeliac disease; microscopic colitis; Crohn’ s disease; ulcerative colitis; microbiota; biological therapies; refractory disease

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Biomechanics of Cardiovascular Remodeling

edited by

Kevin Willy

and Maximilian Doldi Philipp

submission deadline 31 Jul 2025 | 1 articles | Viewed by 433 | Submission Open

Keywords: cardiovascular remodeling; cardiac imaging; cardiovascular intervention; cardiovascular pathways; cardiovascular research; structural heart disease; cellular signaling

(This special issue belongs to the Section Molecular Biophysics)

Plant Genome Evolution and Environmental Adaptation

edited by

Zhonghu Li

submission deadline 31 Jul 2025 | 1 articles | Viewed by 410 | Submission Open

Keywords: plant phylogeny; genome evolution; molecular evolution of cytoplasmic genomes; species divergence

(This special issue belongs to the Section Molecular Plant Sciences)

Nerve Growth Factor (NGF): Molecular Functions and Therapeutic Implications

edited by

Elena Fico

and Pamela Rosso

submission deadline 31 Jul 2025 | Viewed by 343 | Submission Open

Keywords: nerve growth factor; neurotrophic therapy; biomolecules; neurotrophic molecular pathways; neuroprotection; preclinical research; clinical research

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Unraveling the Enigma of Colorectal Cancer: From Mechanisms to Therapeutic Advances

edited by Valentina Belli and

Vincenza Ciaramella

submission deadline 31 Jul 2025 | Viewed by 335 | Submission Open

Keywords: Colorectal cancer; tumour microenvironment; epigenetics; diagnostic molecules; immune evasion; biomarkers; drug resistance; precision medicine; targeted

(This special issue belongs to the Section Molecular Oncology)

Pathophysiological Insights, Biomarkers and New Therapeutic Strategies in Immune-Mediated Disorders and Neurodegenerative Diseases

edited by

Eleonora Virgilio

submission deadline 31 Jul 2025 | Viewed by 331 | Submission Open

Keywords: neurodegeneration; neuroimmunology; inflammation; biomarkers; treatment; pathophysiology; multiple sclerosis; myasthenia gravis; neurodegenerative disease

(This special issue belongs to the Section Molecular Immunology)

Molecular Insights into Innovative Materials and Procedures for Implant and Prosthodontics

edited by

Margherita Tumedei

and

Massimo Del Fabbro

submission deadline 31 Jul 2025 | Viewed by 320 | Submission Open

Keywords: alloys; biomaterials; dental materials; dental implants; implant dentistry; implant-abutment connection; peri-implant diseases; prosthodontics; surface treatments; tissue regeneration

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Novel Insights into the Molecular Mechanisms of Pancreatitis

edited by

Gi-Sang Bae

submission deadline 31 Jul 2025 | Viewed by 285 | Submission Open

Keywords: acute pancreatitis; chronic pancreatitis; pancreatic fibrosis; mechanisms; digestive enzymes; inflammation

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Pharmacology of Protein Kinase Inhibitor

edited by

Liming Hu

submission deadline 31 Jul 2025 | Viewed by 282 | Submission Open

Keywords: protein kinase inhibitor; molecular pharmacology; signaling pathway; preclinical/clinical evaluation; computational modeling; toxicity

(This special issue belongs to the Section Molecular Pharmacology)

Techniques and Strategies in Drug Design and Discovery, 3rd Edition

edited by

George Mihai Nitulescu

submission deadline 31 Jul 2025 | Viewed by 274 | Submission Open

Keywords: drug discovery; drug development; target identification; computational drug design; structure-based drug design; ligand-based drug design

(This special issue belongs to the Section Molecular Pharmacology)

Advances in Bioinformatics of Peptides and Proteins

edited by

Wenying Yan

submission deadline 31 Jul 2025 | Viewed by 245 | Submission Open

Keywords: bioinformatics; peptides; proteins; computational modeling; peptide– protein interactions; multi-omics; peptide and protein design; comparative proteomics; molecular dynamics

(This special issue belongs to the Section Molecular Informatics)

Biosynthesis of Phytochemicals and Their Applications in Novel Drug Lead Development

edited by

Piotr Szymczyk

submission deadline 31 Jul 2025 | 1 articles | Viewed by 241 | Submission Open

Keywords: biosynthesis of phytochemicals in plants; phytochemical isolation; phytochemical structure; animal and human protein targets of phytochemicals; chemical derivatives of phytochemicals

(This special issue belongs to the Section Molecular Pharmacology)

DNA and RNA Nanostructures for the Assembly of Functional Molecules

edited by

Di Liu

and

Kalevi Kairemo

submission deadline 31 Jul 2025 | Viewed by 226 | Submission Open

Keywords: DNA nanotechnology; RNA nanotechnology; biomolecular engineering; biomimetics

(This special issue belongs to the Section Molecular Nanoscience)

Peptide and Protein Metalation

edited by

Antonello Merlino

Irene Russo Krauss

and

Giarita Ferraro

submission deadline 31 Jul 2025 | Viewed by 216 | Submission Open

Keywords: metallodrugs; metal ions; metal complexes; metal– protein interaction; metal– peptide interaction

(This special issue belongs to the Section Biochemistry)

Molecular and Neuromuscular Mechanisms in Skeletal Muscle Aging, 2nd Edition

edited by

Rosa Mancinelli

submission deadline 31 Jul 2025 | Viewed by 209 | Submission Open

Keywords: aging; sarcopenia; neuromuscular junction; molecular muscle modifications; myokines

(This special issue belongs to the Section Molecular Biology)

Advances in Mass Spectrometry-Based Proteomics: From Biomarker Discovery to Translational Applications

edited by

Yanlong Ji

submission deadline 31 Jul 2025 | Viewed by 189 | Submission Open

Keywords: mass spectrometry; LC-MS method development; phosphoproteomics; glycoproteomics; biomarker discovery; multi-omics data integration

(This special issue belongs to the Section Biochemistry)

Cell Death, Inflammation and Oxidative Stress in Neurodegenerative Diseases: 4th Edition

edited by

Anne Vejux

submission deadline 31 Jul 2025 | Viewed by 183 | Submission Open

Keywords: apoptosis; autophagy; necrosis; reticulum stress; natural molecules; oxidative stress; therapeutic; signalling pathways

(This special issue belongs to the Section Molecular Neurobiology)

Gut Microbiome Stability in Health and Disease

edited by

Tomomi Kuwahara

and Yoshitohi Ogura

submission deadline 31 Jul 2025 | Viewed by 182 | Submission Open

Keywords: gut microbiome stability; immune system; epithelial cell; mucous layer; antibiotics; diet; inflammatory bowel disease; gut microbial metabolites

(This special issue belongs to the Section Molecular Microbiology)

Mechanism Research on Listeria monocytogenes and Its Control

edited by

Irene Martín Tornero

submission deadline 31 Jul 2025 | Viewed by 177 | Submission Open

Keywords: Listeria monocytogenes; virulence; biofilm; pathogenicity; control; prevention; food safety

(This special issue belongs to the Section Molecular Microbiology)

Advancements and Trends in Plant Genomics

edited by Rongbin Hu

submission deadline 31 Jul 2025 | Viewed by 177 | Submission Open

Keywords: plant; genomics; next-generation sequencing; third-generation sequencing; CRISPR-Cas

(This special issue belongs to the Section Molecular Plant Sciences)

Endometriosis Pathophysiology, Diagnosis and Emerging Therapeutic Strategies

edited by

Mariarosaria Boccellino

submission deadline 31 Jul 2025 | Viewed by 170 | Submission Open

Keywords: endometriosis; pathophysiology; infertility; biomarkers; pharmacological treatments

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Neurodegenerative Diseases: From Molecular Mechanisms to Pathophysiology (Second Edition)

edited by

Anne Vejux

submission deadline 31 Jul 2025 | 1 articles | Viewed by 167 | Submission Open

Keywords: neurodegenerative diseases; molecular mechanisms; physiology; cell death; autophagy; oxidative stress; inflammation; genetic factors; diet; cognitive functions; exosomes; blood– brain barrier; immunity

(This special issue belongs to the Section Molecular Neurobiology)

Tuberculosis: Host Immunity, Diagnosis and Treatment

edited by

Veronica Edith Garcia

submission deadline 31 Jul 2025 | Viewed by 167 | Submission Open

Keywords: tuberculosis; immune response; diagnosis; treatment; antibiotics; resistance

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Polymer Materials Related to Food Packaging

edited by

Rosie Yagmur Yegin

submission deadline 31 Jul 2025 | Viewed by 159 | Submission Open

Keywords: polymeric materials; food packaging; biodegradable polymers; active packaging; intelligent packaging; nanocomposites; sustainability; circular economy; barrier properties; life cycle assessment

(This special issue belongs to the Section Macromolecules)

The Immune Regulation of Osteoclasts

edited by

J. Kelly Smith

submission deadline 31 Jul 2025 | Viewed by 155 | Submission Open

Keywords: hematopoietic stem cells; osteoclasts; osteoblasts; osteocytes; stromal cells; T cells; B cells; macrophages; dendritic cells; interleukins; cytokines

(This special issue belongs to the Section Molecular Immunology)

Insights in Metabolomics: Chromatography and Mass Spectrometry Applications in Cancer Research

edited by

Catarina Luís

submission deadline 31 Jul 2025 | 1 articles | Viewed by 153 | Submission Open

Keywords: metabolomics; chromatography; mass spectrometry; molecular oncology; cancer pathways; precision medicine

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

The Plant Phenotyping and Phenomics for Breeding

edited by

Jaeil Lyu

submission deadline 31 Jul 2025 | Viewed by 152 | Submission Open

Keywords: plant phenomics; high-throughput phenotyping (HTP); genotype– phenotype association; non-invasive imag-ing; functional genomics; environmental interactions

(This special issue belongs to the Section Molecular Plant Sciences)

Transcription Factors in Plant Gene Expression Regulation, 2nd Edition

edited by

Piotr Szymczyk

submission deadline 31 Jul 2025 | Viewed by 151 | Submission Open

Keywords: plant trans-factor; cis-active sequence; post-translational modification; dimerization and oligomerization; DNA modules

(This special issue belongs to the Section Molecular Plant Sciences)

Latest Research in Photocatalysis

edited by

María Teresa Colomer

submission deadline 31 Jul 2025 | Viewed by 150 | Submission Open

Keywords: design; simulation; synthesis; properties; functionalities; reactions; photocatalysis

(This special issue belongs to the Section Biochemistry)

Molecular Advances in Understanding Plant-Microbe Interactions

edited by

Tomislav Radić

and

Katarina Hančević

submission deadline 31 Jul 2025 | Viewed by 149 | Submission Open

Keywords: phytomicrobiome; symbiosis; pathogen resistance; microbial signalling

(This special issue belongs to the Section Molecular Plant Sciences)

The Neurotoxicity of Amyloid β-Protein

edited by

Haiming Luo

submission deadline 31 Jul 2025 | Viewed by 138 | Submission Open

Keywords: alzheimer’ s disease; amyloid-β ; oligomer; phosphorylated tau; neurotoxicity; oxidative stress; biomarker; early diagnosis; Aβ -targeted therapy

(This special issue belongs to the Section Molecular Neurobiology)

Advancing Mycorrhizal Research for Promoting Plant Growth Under Abiotic Stress

edited by

Catarina Campos

and

Hélia Cardoso

submission deadline 31 Jul 2025 | Viewed by 137 | Submission Open

Keywords: plant-mycorrhizal symbiosis; climate changes; environmental stress; plant stress-tolerance

(This special issue belongs to the Section Molecular Plant Sciences)

Synthesis and Transformations of Bioactive Cyclic Imides

edited by

István Szatmári

submission deadline 31 Jul 2025 | Viewed by 137 | Submission Open

Keywords: PROTAC; phthalimides; maleimides; cyclic imides; targeted protein degradation; protein labeling; antibody–drug conjugates; drug design and synthesis; drug conjugation

(This special issue belongs to the Section Biochemistry)

Genomics and Epigenomics in Molecular Neurobiology

edited by

Ramón Cacabelos

submission deadline 31 Jul 2025 | Viewed by 135 | Submission Open

Keywords: genomics of brain disorders; neuroepigenetics; neurodegenerative disorders; Alzheimer’ s disease; Parkinson’ s disease

(This special issue belongs to the Section Molecular Neurobiology)

New Research on the Biological Activities of Natural Components and Their Application

edited by

Željana Fredotović

submission deadline 31 Jul 2025 | Viewed by 135 | Submission Open

Keywords: natural compounds; traditional and medicinal plants; biological activities

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Metabolic Dynamics and Immune Surveillance in the Tumor Microenvironment

edited by

Jyoti Kaushal

submission deadline 31 Jul 2025 | Viewed by 134 | Submission Open

Keywords: cancer; TME; metabolism; immune cells; signaling pathway; therapy

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Investigating Gut Axes: Pathophysiological Functions and Therapeutic Strategies

edited by

Alessio Ardizzone

and

Sarah Adriana Scuderi

submission deadline 31 Jul 2025 | Viewed by 131 | Submission Open

Keywords: gut– brain axis; gut– heart axis; gut– liver axis; neurological diseases; cancer; novel and alternative therapies; biomarkers

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Leukemias: Molecular Pathogenesis and Influence of the Microenvironment

edited by

Juana Serrano-López

and

Somchai Chutipongtanate

submission deadline 31 Jul 2025 | Viewed by 128 | Submission Open

Keywords: acute myeloid leukemia; bone marrow microenvironment; cell– cell communication; drug resistance; leukemic stem cell; myelodysplastic syndrome; therapeutic strategy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Coagulation Factors and Natural Anticoagulants in Health and Disease

edited by

Zsuzsanna Bereczky

submission deadline 31 Jul 2025 | Viewed by 127 | Submission Open

Keywords: coagulation factor; natural anticoagulant; hemostasis; thrombosis; molecular studies; molecular interactions; structure; functional studies

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Peptide and Protein Drugs Against Infectious Diseases and Allergic Diseases

edited by

Xiumin Wang

submission deadline 31 Jul 2025 | Viewed by 125 | Submission Open

Keywords: peptide and protein drugs; infectious diseases; allergic diseases; hormones; antimicrobial peptides; neuropeptides; cell-penetrating peptides; enzyme inhibitors; vaccines; antibodies

(This special issue belongs to the Section Molecular Pharmacology)

Nanotechnology for Food Science—Innovations and Sustainable Solutions

edited by

Nan Cheng

submission deadline 31 Jul 2025 | Viewed by 124 | Submission Open

Keywords: nanotechnology; nanomaterial synthesis; food safety; food science; nano-engineered food additives; nano-sensors

(This special issue belongs to the Section Molecular Nanoscience)

Displaying special issue 451-500 on page 10 of 69.

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