Molecular Insights into Stroke: Biomarkers and Mechanisms

Dear Colleagues,

Stroke, including both hemorrhagic and ischemic subtypes, remains a leading cause of mortality and long-term disability worldwide, imposing an enormous social and economic burden. Despite advances in acute management, the underlying mechanisms of stroke pathophysiology and reliable biomarkers for prognosis, monitoring, and therapeutic targeting remain incompletely understood. Continuous and in-depth research is therefore essential.

This Special Issue aims to present cutting-edge studies that elucidate the molecular, cellular, and systemic mechanisms of stroke, with a particular focus on biomarker discovery. We especially welcome research investigating the role of the glymphatic system in stroke, as well as studies based on human-derived specimens. Priority will be given to investigations involving human subjects, genomics, proteomics, metabolomics, and other molecular approaches using blood, cerebrospinal fluid, brain tissue, or related biospecimens. Submissions that identify specific pathological mechanisms and translate these findings into clinically relevant biomarkers are highly encouraged.

Through this collection, we seek to advance mechanistic understanding and promote translational research that bridges basic science and clinical application in stroke.

Dr. Jae Sang Oh
Guest Editor

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