Molecular Mechanism of Circadian Rhythm
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 20 November 2025 | Viewed by 12056
Special Issue Editor
Special Issue Information
Dear Colleagues,
The biological clock is essential for regulating bodily functions throughout the day, coordinating the organism’s response to different periods and stimuli to maintain optimal balance. Disruptions in the circadian cycle, often associated with advanced aging and unhealthy lifestyles, can lead to significant imbalances, including increased incidence of various diseases and alterations in sleep and feeding patterns. Research indicates that circadian rhythm dysregulation is correlated with conditions such as metabolic diseases, sleep disorders, and cognitive impairment, highlighting the importance of synchronizing biological rhythms for overall health.
On the other hand, physical exercise has shown preventive and therapeutic potential, helping to maintain homeostasis in older individuals and, in some cases, reversing pathological conditions associated with circadian dysregulation. Regular exercise can improve circadian synchronization, regulate sleep–wake rhythms, and promote metabolic health, demonstrating the beneficial interaction between physical activity and biological rhythms.
Supervised by Guest Editor Dr. Rosângela Vieira de Andrade and assisted by Mr. Matheus Vitorino from Catholic University of Brasilia, this Special Issue of the International Journal of Molecular Sciences, titled “Molecular Mechanism of Circadian Rhythm”, delves into the molecular underpinnings of circadian regulation, with a particular emphasis on the modulating effects of exercise. The articles presented will explore the connections between the circadian cycle, aging, health, and physical exercise. By examining these multifaceted interactions from a molecular perspective, we aspire to foster a deeper understanding of the role of circadian rhythms in maintaining human health and offer new avenues for intervention.
Prof. Dr. Rosângela Vieira de Andrade
Guest Editor
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Keywords
- circadian cycle
- exercise
- aging
- clock genes
- health
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