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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Cellular Oxygen Homeostasis—3rd Edition

edited by

Verena Tretter

submission deadline 20 Sep 2025 | 1 articles | Viewed by 2025 | Submission Open

Keywords: cellular oxygen homeostasis; redox signaling; cellular oxygen sensing; hypoxia; hyperoxia

(This special issue belongs to the Section Molecular Biology)

Antimicrobial Resistology: A New Approach in the Fight Against Antimicrobial Resistance

edited by

Ziad Daoud

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1994 | Submission Open

Keywords: antimicrobial resistance; resistology; ESBL; AmpC; carbapenem resistance; one health

(This special issue belongs to the Section Molecular Pharmacology)

Advanced Molecular Research on Retinopathy and Protection

edited by

Jaeyon Won

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1954 | Submission Open

Keywords: retinopathy; neuroprotection; antioxidants; innovative therapy; emerging technology

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Protein Stability Research: 2nd Edition

edited by

Csaba Magyar

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1909 | Submission Open

Keywords: protein stability; protein degradation; conformational stability and flexibility; thermodynamic stability of proteins; mutation-induced changes in protein stability; stability of oligomeric proteins; stability of protein complexes; thermal adaptation of protein structures; protein aggregation; molten globules; heat shock proteins; chaperones

(This special issue belongs to the Section Molecular Biophysics)

Chronic Liver Disease and Hepatocellular Carcinoma—2nd Edition

edited by

Daniela Gabbia

and Sara Carpi

submission deadline 20 Sep 2025 | 2 articles | Viewed by 1903 | Submission Open

Keywords: hepatocellular carcinoma; NAFLD/NASH; viral hepatitis; autoimmune liver disease; immunotherapy; biomarker

(This special issue belongs to the Section Molecular Oncology)

Amyotrophic Lateral Sclerosis Behind Motor Neurons

edited by

Patrizia Longone

and Ezia Guatteo

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1891 | Submission Open

Keywords: non-neuronal cells; neurotransmitters; systemic disease; motor system; neuronal circuitry; skeletal muscle metabolism; muscle oxidative metabolism

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Research on Type 1 Diabetes and Its Complications: 2nd Edition

edited by

Jolanta Neubauer-Geryk

submission deadline 20 Sep 2025 | 3 articles | Viewed by 1858 | Submission Open

Keywords: type 1 diabetes mellitus; diabetic microangiopathy; diabetic macroangiopathy; continuous glucose monitoring; experimental diabetic models; biomarkers; endothelium dysfunction; diabetes-related diseases; comorbidities; pregnancy; pathophysiology; metabolic syndrome; treatment; precision medicine

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Explore Marine Biodiversity: Discover Insights from Genomics and Transcriptomics

edited by

Maria Sirakov

and Ambrosino Luca

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1850 | Submission Open

Keywords: comparative genomics; functional genomics; transcriptomics; gene expression; adaptation; population genomics; marine biodiversity; evolution

(This special issue belongs to the Section Molecular Genetics and Genomics)

DNA Damage Response from Molecular Mechanisms to Cancer Therapy

edited by Luigi Alfano and

Antonio Giordano

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1843 | Submission Open

Keywords: DNA damage response; synthetic lethality; homologous recombination; cancer therapy

(This special issue belongs to the Section Molecular Oncology)

Reproductive Diseases and Modern Lifestyle: From Bench to Bedside

edited by

Georgios Valsamakis

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1825 | Submission Open

Keywords: infertility; endocrine disrupting chemicals; reproductive hormones; lifestyle; metabolic diseases

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Pathophysiology and New Therapies of Alopecia

edited by Jong-Hyuk Sung

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1758 | Submission Open

Keywords: alopecia; pathophysiology; novel pharmacological treatments; regenerative medicines; gene therapy; cell therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Scleroderma: From Biomarkers to Therapeutic Targets

edited by Kathryn Seraphin Torok

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1745 | Submission Open

Keywords: scleroderma; biomarkers; epigenetics; RNA sequencing; genetics and genomics; therapeutic targets

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Electrochemistry: Molecular Advances and Challenges

edited by

Miguel A. Esteso

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1738 | Submission Open

Keywords: fundamental electrochemistry; electroanalytical techniques; sensors and biosensors; nano-electrochemistry; electrochemical energy production and storage; environmental electrochemistry

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

New Research in Spatial Proteomics

edited by

Andrew Smith

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1728 | Submission Open

Keywords: spatial proteomics; mass spectrometry imaging; mass cytometry; biomarker; machine learning; spatial biology; molecular pathology; cancer

(This special issue belongs to the Section Molecular Informatics)

Human Hereditary Diseases: Advances in Molecular Genetics, Genomics and Therapeutic Strategies

edited by Yulin Jin and

Yujing Li

submission deadline 20 Sep 2025 | 2 articles | Viewed by 1687 | Submission Open

Keywords: hereditary diseases; genetics and genomics; molecular mechanism; gene regulation; therapeutic approach

(This special issue belongs to the Section Molecular Genetics and Genomics)

New Advances in the Field of Thrombosis and Hemostasis

edited by

Claudia Maria Radu

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1663 | Submission Open

Keywords: bleeding; thrombosis; new diagnostic tests; rare diseases; platelet function; biomarkers; risk factors; thrombocytopenia; endothelial dysfunction; autoantibodies; extracellular vesicles; stem cells; gene therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Characterization and Biological Functions of Plant Extracts

edited by

Muna Ali Abdalla

and

Lyndy McGaw

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1642 | Submission Open

Keywords: biological activity of plant-derived products; antimicrobial activity; in vitro antibiofilm activity; anticancer activity; anti-inflammatory activity; secondary metabolites

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Advances in Omics in Agriculture

edited by

Sebastian Wojciech Przemieniecki

submission deadline 20 Sep 2025 | 2 articles | Viewed by 1639 | Submission Open

Keywords: agronomy; plant production; animal production; genome; microbiome; metagenomics; RNAseq; molecular mechnisms; molecular pest diagnostics; molecular interactions; gene editing

(This special issue belongs to the Section Molecular Informatics)

Molecular Dynamics Simulation of Biomolecules

edited by

Pavel Rehak

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1617 | Submission Open

Keywords: molecular dynamics simulations; biochemical processes; biomaterial properties

(This special issue belongs to the Section Molecular Biophysics)

The Blood–Brain Barrier and Neuroprotection

edited by Aruna Sharma and Hari Shanker Sharma

submission deadline 20 Sep 2025 | 2 articles | Viewed by 1598 | Submission Open

Keywords: blood– brain barrier; neurodegenerative diseases; nanoformulations; drug development; delivery systems

(This special issue belongs to the Section Molecular Neurobiology)

Genetic Prediction of Risk of Common Diseases

edited by

Grant Morahan

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1594 | Submission Open

Keywords: complex genetic diseases; cancer; heart disease; diabetes; dementia; polygenic risk score; genetic risk signatures

(This special issue belongs to the Section Molecular Genetics and Genomics)

Gestational Diabetes Mellitus: Molecular Insights into Pathophysiology, Management and Therapy

edited by

Paweł Jan Stanirowski

submission deadline 20 Sep 2025 | 2 articles | Viewed by 1560 | Submission Open

Keywords: GDM pathogenesis; health programming; pharmacogenomics; life-style interventions; fetal growth disorders; preeclampsia; polyhydramnios; placental origin of disease

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Glioblastoma: Molecular Pathogenesis and Treatment

edited by

Maurizio Martini

and

Vincenzo Fiorentino

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1557 | Submission Open

Keywords: glioblastoma; molecular therapy; pathogenesis; immunotherapy; brain tumor

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Type 1 Diabetes: Molecular Mechanisms and Therapeutic Approach

edited by Preeti Chhabra

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1556 | Submission Open

Keywords: type 1 diabetes; microbiome; proteomics; immunotherapy; β -cell replacement; single-cell sequencing; stem cells; gene editing technologies; tolerance

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Chemistry Triggered by Low-Energy Particles

edited by Hassan Abdoul-Carime

submission deadline 20 Sep 2025 | 2 articles | Viewed by 1529 | Submission Open

Keywords: low energy (< 50 eV); photons; electrons; ions; gas phase; single molecules; clusters; condensed phase liquids and films; experimental techniques; density functional theory; IA-based prediction models

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Molecular Mechanism and Therapeutic Approaches of Breast Cancer, Metastatic Breast Cancer, 3rd Edition

edited by

Mi Kyung Park

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1524 | Submission Open

Keywords: breast cancer; metastatic breast cancer; epithelial-to-mesenchymal transition (EMT); epigenetic and post-translational modifications (PTM); tumor microenvironment

(This special issue belongs to the Section Molecular Oncology)

Molecular Advances in Electrochemical Materials

edited by

Raj Karthik

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1511 | Submission Open

Keywords: electrochemical materials; molecular design; energy storage; electrocatalysis; sensing applications; nanomaterials; sustainable materials; hybrid systems; interface engineering; green chemistry

(This special issue belongs to the Section Materials Science)

Phytochemical Dynamics: Plant Metabolite Responses to Environmental Factors

edited by

Ivana Sola

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1503 | Submission Open

Keywords: plant metabolites; phytochemicals; biotic and abiotic factors; environmental influences; biochemical pathways; interactions

(This special issue belongs to the Section Molecular Plant Sciences)

Advances and Current Challenges in Plasma Medicine

edited by

Andrei Vasile Nastuta

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1478 | Submission Open

Keywords: plasma medicine; plasma pharmacology; plasma oncology; plasma bioengineering; plasma agronomy; plasma and food; plasma and automotive; plasma and aerospace; plasma diagnostics; plasma material processing; plasma polymerization and coating; simulation of plasma phenomena during interaction with matter

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Investigation of Natural Products as Sources of Bioactive Molecules, 2nd Edition

edited by

Stefania Garzoli

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1429 | Submission Open

Keywords: metabolomic; secondary metabolites; phytochemical analysis; bioactivity; chemical investigation

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Unraveling the Genetic Background of Neurological Disorders: 2nd Edition

edited by

Vasileios Siokas

Efthimios Dardiotis

and

Ioannis Liampas

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1423 | Submission Open

Keywords: neurological disorders; neurogenetics; personalized treatments; gene-association studies; genetics; genome-wide association studies; genetic linkage studies

(This special issue belongs to the Section Molecular Genetics and Genomics)

Drug-Induced Neurotoxicity and Neurodegeneration: Mechanisms, Models and Implications

edited by

Daniel José Barbosa

and

Renata Silva

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1422 | Submission Open

Keywords: drugs of abuse; pharmaceutical drugs; environmental toxins; drug exposure; neurotoxicity; neurodegeneration; brain health; substance use disorders; therapeutic interventions; in vivo models; in vitro models; in silico models; biomarkers of damage; translational studies

(This special issue belongs to the Section Molecular Neurobiology)

Glutamatergic Signaling in the Nervous System

edited by

Osama Abulseoud

and

Frank Schmitz

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1414 | Submission Open

Keywords: glutamate glutamine cycle; neurotoxicty; ferroptosis; hyperglutamatergic states; innovative pharmacological interventions

(This special issue belongs to the Section Molecular Neurobiology)

Cell Fate Decisions: Autophagy, Apoptosis, Pyroptosis, Necroptosis, Ferroptosis and PANoptosis in Health and Disease

edited by

Yaqiu Wang

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1402 | Submission Open

Keywords: inflammation; autophagy; apoptosis; pyroptosis; necroptosis; PANoptosis; ferroptosis; cell death; cell survival

(This special issue belongs to the Section Molecular Biology)

Hybrid Organic–Inorganic Materials: From Synthesis to Applications

edited by

Mirta Rubčić

and

Višnja Vrdoljak

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1380 | Submission Open

Keywords: hybrid; organic– inorganic; functional materials; structure– property; design; synthesis

(This special issue belongs to the Section Materials Science)

Role of Glia in Human Health and Disease

edited by

Daniele Lana

and

Hajime Hirase

submission deadline 20 Sep 2025 | 3 articles | Viewed by 1375 | Submission Open

Keywords: astrocytes; microglia; oligodendrocytes; Schwann cells; neurodegeneration

(This special issue belongs to the Section Molecular Neurobiology)

Advances in Diabetic Ischemic Heart Failure

edited by Branko Beleslin

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1335 | Submission Open

Keywords: diabetes; ischemic cardiomyopathy; pathophysiology; diagnostics; therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

New Advances in Glioma Knowledge: From Genome to Signal Pathways Alterations

edited by

Sabrina Di Bartolomeo

and Giuseppina D'Alessandro

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1331 | Submission Open

Keywords: gliomas; signalling pathways; genetic alterations; epigenetics; metabolic alterations; drug resistance; glioma stem cells

(This special issue belongs to the Section Molecular Neurobiology)

Multifunctional Nanocomposites for Bioapplications

edited by

Athina Angelopoulou

submission deadline 20 Sep 2025 | 2 articles | Viewed by 1328 | Submission Open

Keywords: nanocomposites; biomedical applications; molecular characteristics; metabolic pathways; biomarkers; external stimuli

(This special issue belongs to the Section Molecular Nanoscience)

Mitochondria as a Therapeutic Target for Anti-Cancer Drugs

edited by

Dalia Marija Kopustinskiene

submission deadline 20 Sep 2025 | Viewed by 1299 | Submission Open

Keywords: mitochondria; cancer; apoptosis; oxidative phosphorylation; Warburg effect; cardiolipin; inflammation

(This special issue belongs to the Section Molecular Oncology)

Advances in Molecular Therapeutics for HIV Co-Infections

edited by

Vishwanath Venketaraman

and

Selvakumar Subbian

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1290 | Submission Open

Keywords: HIV co-infections; molecular therapeutics; Mtb; ART; immune responses

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

The Role of the Endocannabinoid System in Reward- and Addiction-Related Neuroplasticity

edited by

Francisco Navarrete-Rueda

and

María S. García Gutiérrez

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1273 | Submission Open

Keywords: endocannabinoid system; neuroplasticity; reward; addiction; biomarker; therapeutic approach

(This special issue belongs to the Section Molecular Neurobiology)

Novel Nanoparticle Composites: Functionalization and Application

edited by

Jovan M. Nedeljković

and

Vesna Lazić

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1252 | Submission Open

Keywords: nanoparticles; nanocomposites; synthesis; functionalization; interface; photocatalysis; antimicrobial nanoparticles; nanomedicine; theoretical modelling; computer simulations

(This special issue belongs to the Section Molecular Nanoscience)

The Role of Lipids in Human Health

edited by

Angela Maria Rizzo

and Irma Colombo

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1236 | Submission Open

Keywords: lipids; lipidomics; fatty acids; sphingolipids; steroids; metabolism

(This special issue belongs to the Section Biochemistry)

Molecular Research on Tumor Metastasis and Inhibition

edited by

Yu-Chan Chang

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1236 | Submission Open

Keywords: metastasis; epithelial– mesenchymal transition; small-molecule compounds; animal imaging; signal transduction

(This special issue belongs to the Section Molecular Oncology)

Mitochondria and Energy Metabolism Reprogramming in Diseases

edited by

Nadège Bellance

submission deadline 20 Sep 2025 | 2 articles | Viewed by 1227 | Submission Open

Keywords: mitochondrial dysfunctions; energy metabolism; pathophysiological mechanisms; therapeutic targets; physiology of organelle

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Novel Insights into Reproductive Toxicology

edited by Maria Cristina Budani

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1146 | Submission Open

Keywords: endocrine disruptors; environmental toxicants; fertility; heavy metals; lifestyle habits; molecular mechanisms; pregnancy; teratology; teratogenic compounds; reproductive toxicology

(This special issue belongs to the Section Molecular Toxicology)

Molecular Research on Apoptosis and Autophagy in Osteosarcoma

edited by

Hyung-Mun Yun

and

Kyung-Ran Park

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1140 | Submission Open

Keywords: apoptosis; autophagy; bioactive molecule; cancer; necroptosis; osteosarcoma; osteoclast; osteoblast

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Molecular Diagnosis and Targeted Therapies in Ischemic Stroke

edited by Alicia Aliena-Valero and María Castelló-Ruiz

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1121 | Submission Open

Keywords: ischemic stroke; cerebral protection; repair treatments; therapeutic approaches

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Bioconjugates and Application

edited by

Gábor Mező

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1113 | Submission Open

Keywords: bioconjugates; targeted therapy; homing moieties; drug delivery; bioconjugates as diagnostic tools; targeted nanoparticles; antibody– drug conjugates; linkage systems

(This special issue belongs to the Section Macromolecules)

Displaying special issue 701-750 on page 15 of 68.

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