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Chemistry Triggered by Low-Energy Particles

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Physical Chemistry and Chemical Physics".

Deadline for manuscript submissions: 20 September 2025 | Viewed by 962

Special Issue Editor


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Guest Editor
Institut de Physique des 2 Infinis, Université Lyon 1, Université de Lyon, CNRS/IN2P3, UMR5822, F-69003 Lyon, France
Interests: electron and photon-molecule processes; gas phase; molecular solid; mass spectrometry; spectroscopy; radiation science; cold plasma; astrochemistry; surface reaction

Special Issue Information

Dear Colleagues,

The chemistry triggered by low-energy (<50 eV) particles, i.e., photons, electrons, or ions, covers a broad range of fundamental research (e.g., astrochemistry, radiation therapy, etc.), nanoscale design, or sustainable and eco-friendly synthesis methods (e.g., cold plasma, reaction induced by surface plasmon excitation, etc.). As the interaction of these particles with single molecules is relatively well established now due to both experimental and advanced quantum-based theoretical methods, less is documented when single molecules are excited in the presence of a surrounding environment (clusters or aggregates, liquids, molecular films, etc.). The gained knowledge, e.g., reaction processes, cross-sections, and rate constant measurements, will contribute to better model chemical reactions under irradiation and potentially to IA-predicted and -controlled chemical synthesis.

This Special Issue intends to provide a platform dedicated to the experimental and theoretical research on the interaction of low-energy particles with molecules at diverse degrees of aggregation, i.e., from isolated molecules to molecular solids. Original research articles and reviews are especially welcome.

Dr. Hassan Abdoul-Carime
Guest Editor

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Keywords

  • low energy (<50 eV)
  • photons
  • electrons
  • ions
  • gas phase
  • single molecules
  • clusters
  • condensed phase liquids and films
  • experimental techniques
  • density functional theory
  • IA-based prediction models

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Published Papers (2 papers)

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Research

18 pages, 2956 KiB  
Article
Hyperthermal Reactions in DNA Triggered by 1–20 eV Electrons: Absolute Cross Sections for Crosslinks, Strand Breaks, Clustered Damages and Base Modifications
by Yanfang Dong, Xin Huang, Wenlu Zhang, Yu Shao, Pierre Cloutier, Yi Zheng and Léon Sanche
Int. J. Mol. Sci. 2025, 26(9), 4057; https://doi.org/10.3390/ijms26094057 - 25 Apr 2025
Viewed by 127
Abstract
Absolute cross sections (ACSs) are needed to estimate cellular damage induced by high-energy radiation (HER). Low-energy electrons (LEEs), which are the most numerous secondary particles generated by HER, can trigger hyperthermal reactions in DNA. ACSs for such reactions are essential input parameters to [...] Read more.
Absolute cross sections (ACSs) are needed to estimate cellular damage induced by high-energy radiation (HER). Low-energy electrons (LEEs), which are the most numerous secondary particles generated by HER, can trigger hyperthermal reactions in DNA. ACSs for such reactions are essential input parameters to calculate radiobiological effectiveness, particularly in targeted radiotherapy. Using a mathematical model, we generate ACSs from effective damage yields induced by LEE impact on 3197 base-pair plasmid DNA films. Direct or enzyme-revealed conformational damages, quantified by electrophoresis, provide the first complete set of ACSs for inducing crosslinks, double-strand breaks (DSBs), single-strand breaks, base-damage-related crosslinks, non-DSB clustered damages (NDCDs), and isolated base damages. These ACSs are generated across the 1–20 eV range, at one eV intervals. They exhibit a strong energy dependence with maximum values at 10 eV of 3.7 ± 0.8, 3.5 ± 0.6, 45.4 ± 4.1, 2.9 ± 1.1, 5.1 ± 1.4, and 54.0 ± 16.4 × 10−15 cm2, respectively. ACSs for DSBs, NDCDs, and crosslinks clearly indicate that lesions threatening cell function and genetic stability can be generated by a single LEE. At 5 and 10 eV, total damage ACSs are 63% and 80% larger, respectively, than those previously determined for the same plasmids bound to arginine, a constituent of histones protecting DNA. Full article
(This article belongs to the Special Issue Chemistry Triggered by Low-Energy Particles)
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9 pages, 884 KiB  
Article
Synthesis of Resorcinol and Chlorophenol from Irradiation of 1,3-Dichlorobenzene in a Water Ice Environment by Low-Energy Electrons
by Hassan Abdoul-Carime and Janina Kopyra
Int. J. Mol. Sci. 2025, 26(2), 688; https://doi.org/10.3390/ijms26020688 - 15 Jan 2025
Viewed by 583
Abstract
Dichlorobenzene is beneficial to industries, however, the release of this compound into the environment causes significant damage to ecosystems and human health, as it exhibits resistance to biodegradation. Here, we show that chlorophenol and resorcinol are synthesized from 1,3-dichlorobenzene in a water ice [...] Read more.
Dichlorobenzene is beneficial to industries, however, the release of this compound into the environment causes significant damage to ecosystems and human health, as it exhibits resistance to biodegradation. Here, we show that chlorophenol and resorcinol are synthesized from 1,3-dichlorobenzene in a water ice environment (1) directly on a poly-crystalline gold surface and (2) after low-energy (<12 eV) electron irradiation of admixture films. For the latter, at energies below 5.5 eV, the electrons solely decompose the chlorinated compound into radicals that further undergo reaction with surrounding water molecules. At higher energies (i.e., >5.5 eV) additional fragments, e.g., hydroxyl radicals, produced from the dissociation of water molecules, may also be involved in the chemistry. The present results may suggest strategies for potential eco-friendly, sustainable, and scalable processes for the mitigation of these halogenated compounds such as cold plasma and radiation, in which low-energy (<10 eV) electrons are predominantly produced. Full article
(This article belongs to the Special Issue Chemistry Triggered by Low-Energy Particles)
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