The Role of AI and Radiomics in Diagnostic Oncology

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Machine Learning and Artificial Intelligence in Diagnostics".

Deadline for manuscript submissions: 31 October 2025

Special Issue Editors


E-Mail Website
Guest Editor
Unit of Nuclear Medicine, Spirito Santo Hospital, 65100 Pescara, Italy
Interests: PET/CT; radioligand therapy; oncohematology in nuclear medicine; neuroinflammation; prostate cancer; breast cancer and PET/CT

E-Mail Website
Guest Editor
Department of Nuclear Medicine and Theragnostics, “Mariano Santo” Cosenza Hospital, 87100 Cosenza, Italy
Interests: hybrid and molecular imaging; oncologic imaging; cardiovascular radiology; clinical imaging with X-ray; CT; MR; PET/CT; SPECT/CT; interventional diagnostic procedures

Special Issue Information

Dear Colleagues,

The imaging of pathophysiological processes began with the discovery of X-rays by Roentgen and radioactivity by Becquerel, along with the pioneering work of Marie Curie and Saul Hertz. These breakthroughs laid the foundations for modern radiology and nuclear medicine, ultimately leading to the emergence of a theranostics—a hybrid approach to disease management that integrates therapy and diagnostics. This discipline enables us to “treat what we see and see what we treat”. However, as Gillies stated in 2015, “images are data”, and the potential of these data, including those not perceptible to the human eye, is becoming increasingly significant.

Over the past decade, artificial intelligence (AI) has been incorporated into daily clinical practice, frequently surpassing human capabilities in diagnostic imaging and radiation-based therapies. AI can process vast quantities of data, and a transition toward human–AI collaboration is already underway, transforming multiple stages of our workflow, from image acquisition and interpretation to the delivery of personalized care.

This Special Issue explores the following fundamental questions: which AI tools in diagnostic oncology have already transformed our professional workflows, and are we ready to embrace the use of AI, guided by our clinical experience, ethical values, and existing regulatory frameworks?

Dr. Laura Travascio
Dr. Mario Leporace
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • artificial intelligence
  • pathophysiological
  • radiology and nuclear medicine
  • diagnostic imaging
  • diagnostic oncology

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Published Papers

This special issue is now open for submission.
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