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Diagnostics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Artificial Intelligence in Diagnosis and Management of Cardiovascular Diseases

edited by

Corina Maria Vasile

and Xavier Iriart

submission deadline 31 May 2026 | 1 articles | Viewed by 1366 | Submission Open

Keywords: cardiovascular diseases; artificial intelligence; deep learning; machine learning; wearable devices; imaging techniques; personalized medicine; risk prediction; telemedicine; remote monitoring; ethical considerations

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Ocular Surface Alterations in Eyelid Malpositions: Pathophysiology, Diagnostic Tools, and Therapeutic Approaches

edited by Massimiliano Serafino and

Alessandra Di Maria

submission deadline 31 May 2026 | Viewed by 53 | Submission Open

Keywords: lid malpositions and ocular surface disorders; dry eye syndrome; exposure keratopathy; tear film instability; anterior segment imaging; lid surgery outcomes

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Current Diagnosis and Management of Metabolic Bone Disease

edited by Liming Xiong

submission deadline 31 May 2026 | Viewed by 34 | Submission Open

Keywords: metabolic bone disease; bone turnover markers; maintenance of bone homeostasis; multiorgan– bone axis; fracture risk assessment; diabetic osteopathy; precision management

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advanced Diagnosis and Integrated Management of Bone and Soft Tissue Tumors

edited by Tiao Lin

submission deadline 31 May 2026 | Viewed by 30 | Submission Open

Keywords: musculoskeletal neoplasms; diagnostic imaging; molecular pathology; multidisciplinary treatment; personalized medicine; translational research; multidisciplinary collaboration

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Brain Radiation Necrosis: Emerging Insights in Pathophysiology, Diagnosis, and Management

edited by

Nam P. Nguyen

and Gokoulakrichenane Loganadane

submission deadline 31 May 2026 | Viewed by 29 | Submission Open

Keywords: brain radiation necrosis; radiation therapy; multimodal imaging; differential diagnosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advanced Diagnostic Approaches in Cardiovascular Diseases: From Imaging to Biomarkers

edited by

Ovidiu Mitu

and

Lucia Stefania Magda

submission deadline 31 May 2026 | Viewed by 25 | Submission Open

Keywords: medical diagnosis; cardiovascular diseases; imaging; biomarkers; AI-driven analytics

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnosis and Management of Inflammatory Respiratory Diseases

edited by Kęstutis Malakauskas and

Andrius Januskevicius

submission deadline 31 May 2026 | Viewed by 19 | Submission Open

Keywords: asthma; chronic obstructive pulmonary disease; inflammatory respiratory diseases; inflammation; biomarkers; respiratory diagnostics; anti-inflammatory therapy

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Data Science and Artificial Intelligence in Laboratory Medicine

edited by

Fernando Marques-Garcia

submission deadline 1 Jun 2026 | Viewed by 50 | Submission Open

Keywords: artificial intelligence; data science; algorithm; laboratory medicine

(This special issue belongs to the Section Clinical Laboratory Medicine)

New Insights into the Diagnosis of Gynecological Diseases

edited by

Dah Ching Ding

submission deadline 30 Jun 2026 | 4 articles | Viewed by 5962 | Submission Open

Keywords: gynecological diseases; precision medicine; molecular diagnostics; artificial intelligence; biomarkers; next-generation sequencing; imaging technologies; big data

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Innovations in Imaging for Radiation Oncology

edited by

Sara Haseli

and Arash Azhideh

submission deadline 30 Jun 2026 | 1 articles | Viewed by 3655 | Submission Open

Keywords: radiation oncology; diagnostic imaging; artificial intelligence; radiomics; tumor detection; molecular imaging; treatment planning; radiogenomics

(This special issue belongs to the Section Medical Imaging and Theranostics)

Generative AI and Digital Twins in Diagnostics

edited by

Sean Benson

submission deadline 30 Jun 2026 | Viewed by 596 | Submission Open

Keywords: digital twins; electronic health record; generative AI; personalized medicine; clinical practice; simulation

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Innovations in Dermatologic Diagnostics: Integrating Dermoscopy, Imaging, and Non-Surgical Therapies

edited by

Carmen Cantisani

and

Norbert Kiss

submission deadline 30 Jun 2026 | Viewed by 277 | Submission Open

Keywords: dermoscopy; clinical impact and innovation; diagnostic; prognosis; markers; imaging

(This special issue belongs to the Section Biomedical Optics)

Advances in Plastic Surgery: Diagnosis, Management and Prognosis

edited by Konstantinos Seretis

submission deadline 30 Jun 2026 | Viewed by 209 | Submission Open

Keywords: plastic surgery; breast reconstruction; skin graft; diagnosis; prognosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnosis and Management of Adverse Drug Reactions in Precision Medicine and Big Data

edited by

Elena Ramírez

submission deadline 30 Jun 2026 | Viewed by 74 | Submission Open

Keywords: adverse drug reactions; pharmacovigilance; drug safety; risk factors; causality assessment; big data; precision medicine

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Urologic Oncology: Biomarkers, Diagnosis, and Management—2nd Edition

edited by

Roberto Contieri

submission deadline 30 Jun 2026 | Viewed by 28 | Submission Open

Keywords: urologic oncology; biomarkers; diagnosis; management; urothelial carcinoma; prostate cancer; kidney cancer; testis cancer; penile cancer

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Optimization of Clinical Imaging: From Diagnosis to Prognosis, 2nd Edition

edited by

Georg Böning

submission deadline 30 Jun 2026 | Viewed by 8 | Submission Open

Keywords: clinical imaging; medical image analysis; imaging management; computed tomography (CT); magnetic resonance imaging (MRI)

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in the Diagnosis and Management of Autoimmune Diseases

edited by

Micol Romano

and

Dimitri Poddighe

submission deadline 30 Jun 2026 | Viewed by 5 | Submission Open

Keywords: autoimmunity; autoinflammatory diseases; rheumatology; innovative and biological therapies; comorbidity; immune-mediated manifestations

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnosis and Management of Colorectal Diseases, 2nd Edition

edited by

Filippo Carannante

and

Guglielmo Niccolò Piozzi

submission deadline 30 Jun 2026 | Viewed by 2 | Submission Open

Keywords: colorectal diseases; markers; diagnosis; prognosis; screening

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnosis and Management of Neuroendocrine Tumors—2nd Edition

edited by Federica Alessandra Cavalcoli

submission deadline 30 Jun 2026 | Viewed by 2 | Submission Open

Keywords: neuroendocrine neoplasm; pancreatic neuroendocrine neoplasm; gastric neuroendocrine neoplasm; small-bowel neuroendocrine neoplasm; appendicular neuroendocrine neoplasm; lung neuroendocrine neoplasm; functional imaging; cross-sectional imaging; endoscopic ultrasound

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Biomarker-Guided Advances in Diagnostic Medicine

edited by Edvīns Miklaševičs

submission deadline 31 Jul 2026 | 1 articles | Viewed by 451 | Submission Open

Keywords: medical genetics; hereditary cancers; biomarkers; miRNA; microbiome; omics; screening

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

New Insights into Molecular Diagnostic Technologies

edited by Hin Fung Tsang

submission deadline 31 Jul 2026 | Viewed by 271 | Submission Open

Keywords: molecular diagnostics; advanced technologies; disease diagnosis; disease monitoring; disease management; personalized medicine

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Abdominal Ultrasound: A Left Behind Area—2nd Edition

edited by Hiroko Naganuma

submission deadline 31 Jul 2026 | Viewed by 4 | Submission Open

Keywords: liver tumor; drainage vessel; precursor lesion; gallbladder cancer; peritoneum; mesentery; ultrasound

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnosing Respiratory Diseases and Impaired Gas Exchange Using Machine Learning

edited by

Robert LeMoyne

Jakub Rafl

and Martin Rozanek

submission deadline 31 Aug 2026 | 4 articles | Viewed by 8058 | Submission Open

Keywords: machine learning; user trust with machine learning; deep learning; blood gas sensors; oximeters; wearables; computer automated diagnosis of health status; respiratory diseases; impaired gas exchange; advanced diagnostics

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Trends and Diagnosis of Autoimmune Diseases

edited by

Abdulla Watad

and

Yonatan Shneor Patt

submission deadline 31 Aug 2026 | Viewed by 69 | Submission Open

Keywords: autoimmunity; diagnosis; biomarkers; comorbidities; epidemiology; metabolic syndrome; autoinflammatory conditions; psoriasis; cardiovascular disease

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Beyond the Joint: Advances in Musculoskeletal Imaging and Sports Radiology

edited by

Francesco Feletti

submission deadline 30 Oct 2026 | Viewed by 48 | Submission Open

Keywords: sports radiology; musculoskeletal imaging; diagnostic imaging; artificial intelligence; orthopaedics; extreme sports; outdoor sports; outdoor physical activity; one health; health policy

(This special issue belongs to the Section Medical Imaging and Theranostics)

Biological Rhythms in Laboratory Medicine

edited by

Fernando Marques-Garcia

and

Rubén Fossión

submission deadline 31 Oct 2026 | Viewed by 47 | Submission Open

Keywords: biological rhythms; laboratory medicine; biomarkers; physiology

(This special issue belongs to the Section Clinical Laboratory Medicine)

Gastrointestinal Endoscopy: Diagnostic Applications and Safety Evaluation

edited by

Giacomo Emanuele Maria Rizzo