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Diagnostics
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Updates in Vascular and Endovascular Surgery: Pathology, Diagnosis and Management
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Updates in Vascular and Endovascular Surgery: Pathology, Diagnosis and Management

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Clinical Diagnosis and Prognosis".

Deadline for manuscript submissions: 31 October 2025 | Viewed by 985

Special Issue Editors

Dr. Ombretta Martinelli

E-Mail Website
Guest Editor
Vascular Surgery Division, Department of Surgery “Paride Stefanini”, Policlinico Umberto I, “La Sapienza” University of Rome, 00161 Rome, Italy
Interests: arterial and venous pathology; vascular surgery; surgical and endovascular treatment techniques
Dr. Antonio Marzano

E-Mail Website
Guest Editor Assistant
Vascular Surgery Division, Department of Surgery “Paride Stefanini”, Policlinico Umberto I, “La Sapienza” University of Rome, 00161 Rome, Italy
Interests: vascular surgery; endovascular surgery

Special Issue Information

Dear Colleagues,

We are pleased to invite you to contribute to this Special Issue, focused on providing updates on vascular and endovascular surgery. As we all know, technology has made significant advances in the field of vascular surgery, from diagnosis to the treatment of both arterial and venous diseases.

Due to these ongoing innovations, it is becoming increasingly important to understand their proper application and real utility in diagnosing and treating vascular diseases. Accurate clinical research and the creation of international collaborative networks are essential in this context.

The aim of this Special Issue is to investigate the functioning, application, and short-, medium-, and long-term outcomes of the tools currently available in vascular and endovascular surgery.

We welcome the submission of original research articles, reviews, short communications, case reports, and interesting images on the following topics:

  • Diagnosis and surgical and/or endovascular treatment of the aortic arch, thoracic aorta, thoraco-abdominal aorta, abdominal aorta, iliac arteries, supra-aortic trunks, and lower limb arteries;
  • Diagnosis and surgical and/or endovascular treatment of complex venous diseases and lower limb pathologies.

We look forward to receiving your contributions.

Dr. Ombretta Martinelli
Guest Editor

Dr. Antonio Marzano
Guest Editor Assistant

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • aneurysms of the aorta
  • aneurysms of the arch
  • arterial stenosis
  • EVAR (endovascular aneurysm repair)
  • FEVAR (fenestrated endovascular aneurysm repair)
  • BEVAR (branched endovascular aneurysm repair)
  • iliac branches
  • varicose veins
  • venous insufficiency
  • chronic obstructive arteriopathy

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

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Research

10 pages, 208 KiB  
Article
Impact of Sex-Related Differences in Infrarenal Aortic Neck Morphology on Outcomes of Endovascular Aneurysm Repair for Similar-Sized Aortic Aneurysm
by Ombretta Martinelli, Antonio Marzano, Maria Irene Bellini, Roberto Gattuso, Luca Di Marzo, Valeria Gonta, Jihad Jabbour, Wassim Mansour and Simone Cuozzo
Diagnostics 2025, 15(2), 157; https://doi.org/10.3390/diagnostics15020157 - 12 Jan 2025
Viewed by 803
Abstract
Objectives: This study aimed to evaluate whether gender-related anatomical differences in proximal aortic neck morphology affect the feasibility and outcomes of endovascular aortic aneurysm repair (EVAR) in women with abdominal aortic aneurysms (AAA). Methods: This study performed a retrospective analysis of [...] Read more.
Objectives: This study aimed to evaluate whether gender-related anatomical differences in proximal aortic neck morphology affect the feasibility and outcomes of endovascular aortic aneurysm repair (EVAR) in women with abdominal aortic aneurysms (AAA). Methods: This study performed a retrospective analysis of patients electively treated by EVAR for infrarenal AAA between January 2019 and December 2023. Demographics, anatomical characteristics, and stent graft details were analyzed. The primary endpoint was technical success. Secondary endpoints included freedom from aortic and neck-related reinterventions, endoleak rate, and freedom from aneurysm-related mortality during follow-up. Technical aspects, including adherence to the instructions for use (IFUs), were retrospectively analyzed. Results: One-hundred-seventeen patients (fifty-six females; mean age 76.2 ± 5.3 years) underwent elective EVAR for AAA. Demographics and comorbidities were homogeneous across genders. Female patients (Group A) demonstrated a higher prevalence of hostile proximal aortic neck features, including neck length < 10 mm and angulation > 60° (p = 0.009, p = 0.029, respectively) and a higher frequency of off-label EVAR procedures (28.6% vs. 11.5%; p = 0.034). The overall technical success rate was 98.3%, with no significant differences between genders in terms of stent graft selection, use of suprarenal fixation, or incidence of type 1–3 endoleaks. The median follow-up period was 35.2 ± 12.7 months, showing comparable rates of neck-related reinterventions, open conversions, and aneurysm-related mortality between genders. Notably, off-label EVAR was identified as an independent risk factor for type 1A endoleaks, reinterventions, and aneurysm-related mortality (p < 0.00001, p < 0.0001, and p = 0.001, respectively). Conclusions: Female patients undergoing EVAR often present with hostile proximal aortic neck features and are treated at an older age than males. Despite these differences, technical success rates and mid- to long-term outcomes were comparable between genders, with no variation in stent graft selection or suprarenal fixation use. Effective procedural planning, device selection, and surgical expertise appear to mitigate historical gender-related anatomical challenges. Further large-scale studies are needed to confirm whether anatomical factors alone drive outcomes, irrespective of gender. Full article
(This article belongs to the Special Issue Updates in Vascular and Endovascular Surgery: Pathology, Diagnosis and Management)
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