Special Issues

Diagnostics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in the Diagnosis of Gastrointestinal Diseases—2nd Edition
edited by
submission deadline 31 Dec 2025 | 21 articles | Viewed by 63366 | Submission Open
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
Advances in the Diagnostic Imaging of Gastrointestinal Diseases submission deadline 31 Dec 2025 | 14 articles | Viewed by 39194 | Submission Open
Keywords: gastrointestinal diseases; gastrointestinal malignancies; endoscopy; endoscopic ultrasound; confocal laser endomicroscopy; ERCP; ultrasound; CEUS; CT; MRI
(This special issue belongs to the Section Medical Imaging and Theranostics)
Machine-Learning-Based Disease Diagnosis and Prediction
edited by Fakhar Abbas
submission deadline 31 Dec 2025 | 22 articles | Viewed by 37968 | Submission Open
Keywords: development and validation of machine learning models for disease diagnosis and prediction; integration of multimodal data (e.g.; imaging; genomic; and clinical) for enhanced diagnostic accuracy; artificial intelligence in healthcare; ethical and regulatory considerations in the deployment of machine learning for healthcare applications; case studies and applications of machine learning in specific disease domains (e.g.; cancer; cardiovascular diseases; and neurodegenerative disorders); comparative studies and benchmarking of machine learning approaches for disease diagnosis and prediction; healthcare analytics; bioinformatics; medical imaging analysis
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Advances in Artificial Intelligence in Healthcare submission deadline 31 Dec 2025 | 8 articles | Viewed by 21984 | Submission Open
Keywords: artificial intelligence; AI-driven radiomics; healthcare; digital radiology; precision medicine
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
New Developments in the Diagnosis of Skin Tumors
edited by
submission deadline 31 Dec 2025 | 7 articles | Viewed by 19207 | Submission Open
Keywords: basal cell carcinoma; melanoma; benign tumors; cutaneous squamous cell carcinoma; Bowen’ s disease; actinic keratosis; diagnosis; biomarkers; imaging techniques; molecular diagnostics; histopathology; precision medicine
(This special issue belongs to the Section Medical Imaging and Theranostics)
Orthopedics and the Musculoskeletal System: Diagnosis, Prognosis, and Mechanisms
edited by Nahum Rosenberg
submission deadline 31 Dec 2025 | 10 articles | Viewed by 17524 | Submission Open
Keywords: muscle biology; muscle rehabilitation; orthopedic imaging; orthopedic diagnosis; orthopedic trauma; fracture healing
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Inflammatory Pathologies
edited by Uday Nagesh Shivaji
submission deadline 31 Dec 2025 | 6 articles | Viewed by 15791 | Submission Open
Keywords: systemic chronic inflammation; biomarkers of inflammation; imaging in inflammatory pathology
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
Artificial Intelligence Advances for Medical Computer-Aided Diagnosis—2nd Edition submission deadline 31 Dec 2025 | 6 articles | Viewed by 15671 | Submission Open
Keywords: image classification; image segmentation; medical image processing; biomedical optical imaging; medical signal processing; artificial intelligence; deep learning; machine learning; computer-aided diagnosis; explainable artificial intelligence
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Artificial Intelligence in Pathological Image Analysis—2nd Edition
edited by
submission deadline 31 Dec 2025 | 6 articles | Viewed by 15484 | Submission Open
Keywords: histopathology; cytopathology; molecular pathology; surgical pathology; digital pathology; microscopy; whole slide image (WSI); clinical data; computer vision; deep learning; machine learning; computation; mathematics; domain adaptation; segmentation; classification; pattern recognition; explainable AI; reconstruction
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Advances in Fetal Diagnosis and Therapy
edited by Elisa Montaguti
submission deadline 31 Dec 2025 | 4 articles | Viewed by 15391 | Submission Open
Keywords: ultrasound; prenatal diagnosis; NIPT; fetal echocardiography; fetal therapy; fetal MRI
(This special issue belongs to the Section Medical Imaging and Theranostics)
Artificial Intelligence for Clinical Diagnostic Decision Making submission deadline 31 Dec 2025 | 5 articles | Viewed by 13193 | Submission Open
Keywords: artificial intelligence; machine learning; clinical decision support systems; health disparity; medical imaging; disease diagnosis; medical errors; patient safety
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Clinical Presentation, Management and Prognosis of Infective Endocarditis
edited by , Alexander Weymann and Thanos Athanasiou
submission deadline 31 Dec 2025 | 2 articles | Viewed by 12807 | Submission Open
Keywords: infective endocarditis; clinical presentation; diagnostic modalities; antibiotic stewardship; surgical interventions; prognostic indicators
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Latest Advances and Prospects in Cardiovascular Imaging
edited by Carlo Liguori
submission deadline 31 Dec 2025 | 5 articles | Viewed by 12807 | Submission Open
Keywords: cardiovascular imaging; cardiovascular magnetic resonance; coronary angiography; echocardiography; artificial intelligence
(This special issue belongs to the Section Medical Imaging and Theranostics)
Optical Imaging: Trends, Impact, and Application in Medical and Biomedical Diagnostics submission deadline 31 Dec 2025 | 6 articles | Viewed by 11758 | Submission Open
Keywords: vascular and tumor imaging; drug testing; blood flow characterization; tissue characterization and cell migration analysis; fluorescence microscopy (FM); optical coherence tomography (OCT); ultrasound imaging (sonography); multiphoton microscopy (MPM); photoacoustic tomography (PAT); computed tomography (CT); conebeam computed tomography (CBCT); magnetic resonance imaging (MRI); endoscopy; scanning laser ophthalmoscopy; super-resolution microscopy; hyperspectral imaging; diffuse optical tomography; spectroscopy; structured illumination microscopy (SIM); laser doppler imaging; artificial intelligence; machine learning; algorithm development
(This special issue belongs to the Section Biomedical Optics)
The Role of AI in Ultrasound
edited by
submission deadline 31 Dec 2025 | 5 articles | Viewed by 11266 | Submission Open
Keywords: artificial intelligence; medical ultrasound; diagnostic imaging; automated image interpretation; predictive modeling; personalized medicine; clinical workflow optimization; healthcare access; multidisciplinary innovation
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Current Challenges and Perspectives of Ultrasound, 2nd Edition submission deadline 31 Dec 2025 | 5 articles | Viewed by 10957 | Submission Open
Keywords: ultrasound; contrast-enhanced ultrasound (CEUS); endoscopic ultrasound; strain imaging; shear wave elastography; fusion imaging; endoscopic ultrasound
(This special issue belongs to the Section Medical Imaging and Theranostics)
Neurological Diseases: Biomarkers, Diagnosis and Prognosis submission deadline 31 Dec 2025 | 9 articles | Viewed by 10195 | Submission Open
Keywords: biomarkers; neurological diseases; multiple sclerosis; traumatic brain injury; peripheral neuropathies; COVID-19 neurological-associated damage; diagnosis; prognosis.
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Recent Advances and Challenges in Gastrointestinal Endoscopy
edited by
submission deadline 31 Dec 2025 | 6 articles | Viewed by 9845 | Submission Open
Keywords: diagnosis at an early stage; endoscopy; precancerous lesion
(This special issue belongs to the Section Biomedical Optics)
Advances in Computed Tomography Imaging for Clinical Diagnosis—2nd Edition
edited by Ibrahim Yel
submission deadline 31 Dec 2025 | 5 articles | Viewed by 9774 | Submission Open
Keywords: computed tomography imaging; clinical diagnosis; dual-energy CT; photon-counting CT; image analysis
(This special issue belongs to the Section Medical Imaging and Theranostics)
Current Issues on Kidney Diseases Diagnosis and Management 2025
edited by
submission deadline 31 Dec 2025 | 6 articles | Viewed by 9195 | Submission Open
Keywords: kidney diseases; renal involvement; AKI; CKD; glomerulopathies; diagnosis; treatment; dialysis; epidemiology; nephritic syndrome; nephrotic syndrome; biomarkers; urinalysis; oliguria; poliuria; electrolytes; acid-base balance
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Advances in the Diagnosis and Management of Breast Cancer submission deadline 31 Dec 2025 | 4 articles | Viewed by 8148 | Submission Open
Keywords: prognostic and predictive factors; breast carcinoma; phylloid tumor; immunohistochemistry; diagnosis; breast cancer
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
Skin and Cutaneous Adnexal Tumors: Diagnosis and Management—2nd Edition submission deadline 31 Dec 2025 | 2 articles | Viewed by 8006 | Submission Open
Keywords: cutaneous adnexal tumors; follicular and sebaceous tumors; sweat gland tumors
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
Novel Methods and Devices for Monitoring and Diagnosing in Critical Care
edited by
submission deadline 31 Dec 2025 | 6 articles | Viewed by 7841 | Submission Open
Keywords: hemodynamic monitoring; perfusion; heart-lung interactions; novel biomarkers; machine learning; ultrasound; therapeutic drug monitoring; wearable sensors
(This special issue belongs to the Section Point-of-Care Diagnostics and Devices)
Nephrology: Diagnosis and Management
edited by Elio Antonucci
submission deadline 31 Dec 2025 | 4 articles | Viewed by 7676 | Submission Open
Keywords: kidney disease; nephropathy; diagnosis management; renal disease
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
Advancements in Diagnostic Tools in the Emergency Department (ED): A Possible Help to Avoid Overcrowding
edited by Jacopo M. Legramante
submission deadline 31 Dec 2025 | 2 articles | Viewed by 7529 | Submission Open
Keywords: critical care; emergency medicine; diagnostics
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
Diagnostic and Prognostic Markers in Liver Diseases
edited by
submission deadline 31 Dec 2025 | 4 articles | Viewed by 7475 | Submission Open
Keywords: diagnostic and prognostic markers; non-invasive biomarkers; hepatology; liver disease; therapeutic response; disease progression; fibrosis; mortality; decompensation; infection
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
Advances in the Diagnosis and Management of Neuropsychiatric Disorders—2nd Edition submission deadline 31 Dec 2025 | 3 articles | Viewed by 6956 | Submission Open
Keywords: neuropsychiatric disorders; autism; mania; depression; imaging; diagnosis; prognosis
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Artificial Intelligence in Dermatology
edited by Choon Chiat Oh
submission deadline 31 Dec 2025 | 4 articles | Viewed by 6468 | Submission Open
Keywords: dermatology; artificial intelligence; deep learning; skin cancers; diagnostic imaging
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Genetic and Genomic Biomarkers in Cancer Diagnosis, Prognosis, and Treatment Prediction
edited by
submission deadline 31 Dec 2025 | 6 articles | Viewed by 6413 | Submission Open
Keywords: cancer genetics and genomics; diagnostic tests; prognostic tests; predictive tests; nucleic acid; companion diagnostics; targeted therapy
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
Ultrasound Diagnosis and Guided Intervention of Musculoskeletal/Neuromuscular Pathology, Second Edition
edited by
submission deadline 31 Dec 2025 | 3 articles | Viewed by 5626 | Submission Open
Keywords: diagnosis; ultrasound; pain; muscle; tendon; nerve; rehabiltation
(This special issue belongs to the Section Medical Imaging and Theranostics)
Advances in Echocardiography
edited by Grazia Canciello
submission deadline 31 Dec 2025 | 2 articles | Viewed by 5611 | Submission Open
Keywords: echocardiography; cardiovascular imaging; three-dimensional echocardiography; strain imaging; TrueVue imaging; cardiac function assessment; clinical applications; non-invasive cardiology; artificial intelligence
(This special issue belongs to the Section Medical Imaging and Theranostics)
Liquid Biopsy: Cancer Diagnostic Biomarkers of the Future
edited by
submission deadline 31 Dec 2025 | 4 articles | Viewed by 5491 | Submission Open
Keywords: liquid biopsy; circulating tumor cells (CTCs); ctDNA testing; exosomes; blood analytes
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
Pathology and Diagnosis of Gynecologic Diseases, 3rd Edition
edited by and Mariateresa Mirandola
submission deadline 31 Dec 2025 | 4 articles | Viewed by 5190 | Submission Open
Keywords: gynecologic pathology; breast pathology; placental pathology; diagnostic pitfalls; differential diagnosis; molecular biology; immunohistochemistry; in situ hybridization
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
Advances in the Diagnosis and Management of Bone Diseases in 2025
edited by Hans-Christof Schober
submission deadline 31 Dec 2025 | 3 articles | Viewed by 4908 | Submission Open
Keywords: osteoporosis; diagnostic; morphology; forces; muscle strength; therapy
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Diagnostic Techniques in Obstetrics and Gynecology: Current Practices and Future Directions
edited by Giuseppina Porcaro
submission deadline 31 Dec 2025 | 4 articles | Viewed by 4907 | Submission Open
Keywords: diagnosis; prognosis; obstetrics and gynecology markers; clinical practice and patient care
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Recent Advances in Sepsis
edited by
submission deadline 31 Dec 2025 | 3 articles | Viewed by 4802 | Submission Open
Keywords: sepsis; biomarkers; diagnosis; personalized medicine
(This special issue belongs to the Section Clinical Laboratory Medicine)
Advances in the Diagnosis of Infectious Diseases and Microorganisms: 2nd Edition
edited by
submission deadline 31 Dec 2025 | 5 articles | Viewed by 4775 | Submission Open
Keywords: clinical microbiology; antimicrobial resistance; diagnostic microbiology; molecular microbiology; HIV; infectious diseases
(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)
Diagnosis and Management of Musculoskeletal Disorders submission deadline 31 Dec 2025 | 3 articles | Viewed by 4501 | Submission Open
Keywords: musculoskeletal diseases; MRI; shoulder and elbow; Bone Necrosis; Wrist Arthroscopy  
(This special issue belongs to the Section Medical Imaging and Theranostics)
Lung Cancer: Screening, Diagnosis and Management: 2nd Edition
edited by
submission deadline 31 Dec 2025 | 3 articles | Viewed by 4406 | Submission Open
Keywords: lung cancer; LDCT; overdiagnosis; artificial intelligence; deep learning; prognosis; radiomics; texture analysis; thoracic surgery
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Pathology and Diagnosis of Head and Neck Diseases
edited by
submission deadline 31 Dec 2025 | 3 articles | Viewed by 4235 | Submission Open
Keywords: head and neck disease; histopathology; oral tumors; cancer; biomarkers; digital pathology; AI applications; personalized medicine
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
Clinical Diagnosis and Management in Emergency and Hospital Medicine
edited by
submission deadline 31 Dec 2025 | 4 articles | Viewed by 4180 | Submission Open
Keywords: diagnosis; treatment; management; hospital medicine; emergency medicine; point-of-care ultrasound; decision making; transitional care; palliative care; quality improvement
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Advances in Cardiovascular Diseases: Diagnosis and Management
edited by Hezzy Shmueli
submission deadline 31 Dec 2025 | 4 articles | Viewed by 4067 | Submission Open
Keywords: real-time imaging; cardiovascular disease; cardiovascular imaging; echocardiography; cardiac CT; cardiac MRI; cardiac nuclear scan; acute cardiac care; artificial intelligence; cardiomyopathy
(This special issue belongs to the Section Medical Imaging and Theranostics)
Eosinophilic Gastrointestinal Disorders: Advances in Diagnosis and Management submission deadline 31 Dec 2025 | 1 articles | Viewed by 4020 | Submission Open
Keywords: eosinophilic esophagitis; diagnosis; treatment; histology; epidemiology; risk factors; endoscopy; high resolution manometry; dietary therapy
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Advances in Dental Diagnostics
edited by and Margherita Fontana
submission deadline 31 Dec 2025 | 3 articles | Viewed by 3881 | Submission Open
Keywords: diagnosis; diagnostic imaging; artificial intelligence; caries; periodontitis; stomatognathic diseases
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Recent Advances in Epidemiological Diagnostics: Detecting and Controlling Infectious Diseases
edited by and W. Sumner Davis
submission deadline 31 Dec 2025 | 5 articles | Viewed by 3866 | Submission Open
Keywords: epidemiological diagnostics; disease control; clinical practice and patient care; public health; infectious diseases
(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)
Metabolic Diseases: Diagnosis, Management, and Pathogenesis
edited by Dee Pei
submission deadline 31 Dec 2025 | 4 articles | Viewed by 3802 | Submission Open
Keywords: metabolic disease; obesity; aging; machine learning; pathophysiology; prevalence; ethnic differences
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
Clinical Impacts and Challenges in Capsule Endoscopy submission deadline 31 Dec 2025 | 2 articles | Viewed by 3616 | Submission Open
Keywords: capsule endoscopy; diagnostic endoscopy; small bowel evaluation; non-invasive exploration
(This special issue belongs to the Section Biomedical Optics)
Pathology and Diagnosis of Neurological Disorders, 2nd Edition
edited by James Yip
submission deadline 31 Dec 2025 | 2 articles | Viewed by 3556 | Submission Open
Keywords: stroke; CNS tumors; neurodegenerative diseases; traumatic brain injury
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
Alzheimer's Disease: Diagnosis, Pathology and Management
edited by
submission deadline 31 Dec 2025 | 2 articles | Viewed by 3386 | Submission Open
Keywords: Alzheimer's disease; neuropathology; PET; MRI; CT; dementia; neurodegeneration; immunotherapy; treatment strategy; disease management
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
New Technologies and Tools Used for Risk Assessment of Diseases
edited by
submission deadline 31 Dec 2025 | 3 articles | Viewed by 3361 | Submission Open
Keywords: digital health; AI in healthcare; machine learning; disease risk prediction; medical imaging; wearable technology; big data analytics; telemedicine; personalized medicine; explainable AI
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
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