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Diagnostics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Thyroid Cancer: Types, Symptoms, Diagnosis and Management

edited by

Mara Carsote

, Mihai-Lucian Ciobica and

Claudiu Nistor

submission deadline 31 Aug 2025 | Viewed by 400 | Submission Open

Keywords: thyroid neoplasia; thyroiditis; imaging; functional imaging; thyroidectomy; tumor markers; histological exam; molecular findings; pediatric population; pregnancy and thyroid conditions

(This special issue belongs to the Section Medical Imaging and Theranostics)

Risk and Prediction of Sudden Cardiac Death and Arrhythmias

edited by

Marisa Varrenti

submission deadline 31 Aug 2025 | Viewed by 324 | Submission Open

Keywords: arrhythmic risk stratification; sudden death; genetics; cardiomyopathy; cardiac magnetic resonance; ventricular arrhythmias; heart failure

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Recent Advances in the Diagnosis and Management of Respiratory Diseases

edited by Elio Antonucci

submission deadline 31 Aug 2025 | 1 articles | Viewed by 315 | Submission Open

Keywords: respiratory disease diagnosis; advanced diagnostic techniques; respiratory management strategies; therapeutic innovations; pulmonary pathophysiology; chronic obstructive pulmonary disease (COPD); asthma management; interstitial lung diseases; respiratory infection

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Integrating Health Informatics and Artificial Intelligence for Advanced Medicine

edited by

Joaquim Carreras

submission deadline 31 Aug 2025 | Viewed by 264 | Submission Open

Keywords: artificial intelligence; machine learning; artificial neural networks; prognosis; treatment; medicine; health care; pathology

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Recent Progress in Abdominal Ultrasound

edited by Andrea Boccatonda,

Antonio Corvino

and

Giulio Cocco

submission deadline 31 Aug 2025 | Viewed by 214 | Submission Open

Keywords: ultrasound; abdomen; CEUS; doppler; bowel

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnosis of Aortic Stenosis—2nd Edition

edited by

Maria Angela Losi

submission deadline 31 Aug 2025 | Viewed by 214 | Submission Open

Keywords: aortic stenosis; diagnosis; prognosis; cardiovascular imaging; echocardiography

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnosis and Management of Retinopathy—2nd Edition

edited by

Joanna Gołȩbiewska

submission deadline 31 Aug 2025 | Viewed by 207 | Submission Open

Keywords: diabetic retinopathy; hypertensive retinopathy; inherited retinal diseases; imaging; OCT

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnostic Challenges in Sports Cardiology—2nd Edition

edited by

Łukasz A. Małek

submission deadline 31 Aug 2025 | 1 articles | Viewed by 203 | Submission Open

Keywords: sports cardiology; MRI; echocardiography; heart rate

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Plastic Surgery: Diagnosis, Management and Prognosis

edited by Konstantinos Seretis

submission deadline 31 Aug 2025 | Viewed by 184 | Submission Open

Keywords: plastic surgery; breast reconstruction; skin graft; diagnosis; prognosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Artificial Intelligence and Big Data in Digestive Healthcare

edited by Hélder Cardoso and

Miguel Mascarenhas

submission deadline 31 Aug 2025 | Viewed by 161 | Submission Open

Keywords: artificial intelligence; big data; digestive system diseases; digestive system neoplasms; electronic health records; endoscopy; precision medicine

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances in Nuclear Medicine and Molecular Imaging

edited by

Gabriele Masselli

submission deadline 31 Aug 2025 | Viewed by 158 | Submission Open

Keywords: cancer; cardiovascular imaging; neurodegenerative conditions; computed tomography; molecular imaging; neuroimaging; positron emission tomography (PET); single-photon emission computed tomography (SPECT); nuclear medicine; molecular imaging; theranostics; response evaluation

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnosis and Management of Fungal Infections: Recent Advances and Coming Challenges

edited by Emily Avitan-Hersh

submission deadline 31 Aug 2025 | Viewed by 158 | Submission Open

Keywords: fungal infection diagnosis; management strategies; antifungal therapy; collaborative care; diagnostic techniques

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Diagnostic Radiology in Head and Neck Diseases

edited by

Daniel Thomas Ginat

submission deadline 31 Aug 2025 | Viewed by 156 | Submission Open

Keywords: head ; neck ; imaging ; radiology ; magnetic resonance imaging ; computed tomography

(This special issue belongs to the Section Medical Imaging and Theranostics)

Pathophysiologic Mechanisms, Diagnosis and Management of Venous Thromboembolism

edited by Emanuele Valeriani

submission deadline 31 Aug 2025 | Viewed by 155 | Submission Open

Keywords: anticoagulants; deep vein thrombosis; diagnosis; pathophysiology; pulmonary embolism; venous thrombosis

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Traumatology: The Essential Role of Imaging in Diagnosis and Management

edited by

Meng-Yu Wu

and

Jui-Yuan Chung

submission deadline 31 Aug 2025 | Viewed by 144 | Submission Open

Keywords: traumatology; injury; mortality; functional outcomes; prehospital care; triage

(This special issue belongs to the Section Medical Imaging and Theranostics)

Prenatal Diagnosis: From Morphological Evaluation to Genetic Testing

edited by

Antonio Pizzuti

and

Gioia Mastromoro

submission deadline 31 Aug 2025 | Viewed by 135 | Submission Open

Keywords: prenatal diagnosis; fetal ultrasound (US); fetal magnetic resonance imaging (MRI); chromosomal microarray analysis; next-generation sequencing; exome sequencing; genome sequencing; non-invasive prenatal screening; non-invasive prenatal diagnosis

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Innovative Advances in Diagnosis Through Artificial Intelligence

edited by Jorge Mateo Sotos

submission deadline 31 Aug 2025 | Viewed by 135 | Submission Open

Keywords: artificial intelligence; medical diagnostics; predictive analytics; machine learning; deep learning; digital pathology; early disease detection; personalized medicine; smart healthcare

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Application of Cone Beam Computed Tomography for Maxillofacial Diseases, Third Edition

edited by

Yiu Yan Leung

submission deadline 31 Aug 2025 | Viewed by 135 | Submission Open

Keywords: cone-beam computed tomography; imaging; radiology; oral and maxillofacial surgery; dentistry; diagnosis; risk management; 3D printing; artificial intelligence

(This special issue belongs to the Section Medical Imaging and Theranostics)

Innovative Diagnostic Imaging Technology in Musculoskeletal Tumors

edited by

Min Wook Joo

submission deadline 31 Aug 2025 | Viewed by 134 | Submission Open

Keywords: musculoskeletal tumors; diagnostic imaging; innovative technology; advanced imaging modalities; tumor classification; tumor staging; imaging protocols; image analysis techniques

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnosis and Management of Spinal Diseases

edited by Jwo-Luen Pao

submission deadline 31 Aug 2025 | 1 articles | Viewed by 127 | Submission Open

Keywords: spinal diseases; spinal conditions; endoscopy; artificial intelligence (AI); radiological techniques; MRI; CT scans; X-rays; management

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Neurofibromatosis and Schwannomatosis: Diagnosis and Management

edited by Walter Taal and Enrico Martin

submission deadline 31 Aug 2025 | Viewed by 119 | Submission Open

Keywords: neurofibromatosis type 1 (NF1); neurofibromatosis type 2 (NF2); schwannomatosis (SWN); neurofibromas; schwannomas; malignant peripheral nerve sheath tumor (MPNST); glioma; tumor management; genetic counseling; quality of life (QoL)

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Game-Changing Concepts in Reproductive Health

edited by Mark I. Evans and Christian R. Macedonia

submission deadline 31 Aug 2025 | Viewed by 88 | Submission Open

Keywords: pregnancy; artificial intelligence; prenatal diagnosis; genetic sequencing; diagnostic tests; screening tests; public policy; electronic fetal monitoring; introducing new technologies

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Current Trends and Future Directions in Radiotheragnostic Research: A Special Issue in Collaboration with ISRT 2025

edited by

Kalevi Kairemo

submission deadline 31 Aug 2025 | Viewed by 71 | Submission Open

Keywords: precision oncology; oncology; positron emission tomography; radionuclide therapy; targeted therapy; targeted alpha therapy; PSMA; prostate cancer; neuroendocrine neoplasms; somatostatin analogs; daughter radionuclides; dosimetry; small-scale/micro-dosimetry; radiobiology; target chemistry

(This special issue belongs to the Section Medical Imaging and Theranostics)

Eye Diseases: Diagnosis and Management—2nd Edition

edited by

Ramin Khoramnia

submission deadline 30 Sep 2025 | 19 articles | Viewed by 32764 | Submission Open

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Deep Learning in Medical and Biomedical Image Processing

edited by

Shuyue Guan

submission deadline 30 Sep 2025 | 8 articles | Viewed by 22144 | Submission Open

Keywords: deep learning; medical and biomedical image processing; model explainability and evaluation; generative model; machine learning

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Machine-Learning-Based Disease Diagnosis and Prediction

edited by Fakhar Abbas

submission deadline 30 Sep 2025 | 15 articles | Viewed by 19153 | Submission Open

Keywords: development and validation of machine learning models for disease diagnosis and prediction; integration of multimodal data (e.g.; imaging; genomic; and clinical) for enhanced diagnostic accuracy; artificial intelligence in healthcare; ethical and regulatory considerations in the deployment of machine learning for healthcare applications; case studies and applications of machine learning in specific disease domains (e.g.; cancer; cardiovascular diseases; and neurodegenerative disorders); comparative studies and benchmarking of machine learning approaches for disease diagnosis and prediction; healthcare analytics; bioinformatics; medical imaging analysis

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Respiratory Diseases: Diagnosis and Management

edited by Ori Wand and

Shimon Izhakian

submission deadline 30 Sep 2025 | 10 articles | Viewed by 15966 | Submission Open

Keywords: interstitial lung diseases; chronic obstructive pulmonary disease; asthma; COVID-19; lung cancer; interventional pulmonology

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

New Diagnostic and Testing Strategies for Infectious Diseases

edited by

Fernanda De-Paris

submission deadline 30 Sep 2025 | 8 articles | Viewed by 15918 | Submission Open

Keywords: infectious diseases diagnosis; clinical laboratory techniques; molecular biology; infection control; virulence

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Imaging Diagnosis in Abdomen, 2nd Edition

edited by

Piero Boraschi

and

Francescamaria Donati

submission deadline 30 Sep 2025 | 8 articles | Viewed by 14374 | Submission Open

Keywords: ultrasound computed tomography; MR imaging; PET imaging diagnosis; oncologic imaging; therapeutic response assessment; biomarkers; multidisciplinary management

(This special issue belongs to the Section Medical Imaging and Theranostics)

Periodontal Disease: Diagnosis and Management

edited by

Francesco D’Ambrosio

submission deadline 30 Sep 2025 | 7 articles | Viewed by 10621 | Submission Open

Keywords: periodontal disease; periodontitis; management; diagnosis; biomarker; periodontology

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in Endoscopy

edited by

Emanuele Sinagra

and

Francesco Vito Mandarino

submission deadline 30 Sep 2025 | 5 articles | Viewed by 10279 | Submission Open

(This special issue belongs to the Section Medical Imaging and Theranostics)

Clinical Diagnosis and Management in Cardiology

edited by

Oskars Kalejs

submission deadline 30 Sep 2025 | 10 articles | Viewed by 9148 | Submission Open

Keywords: cardiology; heart disease; arrhythmia; myocardial infarction; angina pectoris; coronary artery disease; echocardiography

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Laboratory Markers of Human Disease

edited by

Mina Hur

submission deadline 30 Sep 2025 | 6 articles | Viewed by 8595 | Submission Open

Keywords: laboratory biomarkers; genomic; proteomics; molecular diagnostics; clinical chemistry

(This special issue belongs to the Section Clinical Laboratory Medicine)

Challenges in Urology: From the Diagnosis to the Management

edited by

and

submission deadline 30 Sep 2025 | 5 articles | Viewed by 8588 | Submission Open

Keywords: challenges; complications; rare; surgery; cancer

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Imaging for the Diagnosis of Obstetric and Gynecological Diseases

edited by

Nicolae Gica

submission deadline 30 Sep 2025 | 5 articles | Viewed by 6992 | Submission Open

Keywords: diagnosis; imaging; gynecology and obstetrics; gynecological cancer; hysteroscopy; ovarian disease

(This special issue belongs to the Section Medical Imaging and Theranostics)

The Future of Diagnostics: Exploring the Role of Artificial Intelligence in Medicine

edited by

Shang-Ming Zhou

, Neil Vaughan and Jiaxiang Zhang

submission deadline 30 Sep 2025 | 3 articles | Viewed by 6731 | Submission Open

Keywords: diagnostics; artificial intelligence; medicine; healthcare; future

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Soft Tissue Sarcoma: From Diagnosis to Prognosis

edited by

Consolato M. Sergi

submission deadline 30 Sep 2025 | 3 articles | Viewed by 5318 | Submission Open

Keywords: soft tissue; mesenchyme; bone; pathogenesis; miRNA; imaging; diagnosis; therapy

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advanced Musculoskeletal Imaging in Clinical Diagnostics

edited by

Hans-Jonas Meyer

submission deadline 30 Sep 2025 | 5 articles | Viewed by 5066 | Submission Open

Keywords: musculoskeletal imaging; cancer imaging; textural analysis; radiomics; MRI; CT; PET

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnostic Imaging in Gastrointestinal and Liver Diseases

edited by

Ruxandra Mare

and

Ioan Sporea

submission deadline 30 Sep 2025 | 4 articles | Viewed by 4200 | Submission Open

Keywords: ultrasonography; elastography; multiparametric ultrasound; contrast-enhanced ultrasound; endoscopic ultrasound; contrast-enhanced endoscopic ultrasound; computer tomography; magnetic resonance imaging; gastrointestinal diseases; diffuse liver disease; focal liver lesions

(This special issue belongs to the Section Medical Imaging and Theranostics)

New Trends in the Diagnosis of Gynecological and Obstetric Diseases

edited by

Razvan Socolov

and Laurentiu Pirtea

submission deadline 30 Sep 2025 | 3 articles | Viewed by 4011 | Submission Open

Keywords: obstetrics and gynecology diagnostics; screening; artificial intelligence; test accuracy

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in Inflammation and Infection Imaging

edited by

Giorgio Treglia

submission deadline 30 Sep 2025 | 3 articles | Viewed by 3998 | Submission Open

Keywords: imaging; infection; inflammation; radiology; nuclear medicine; molecular imaging; hybrid imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Artificial Intelligence in the Diagnostics of Dental Diseases, 2nd Edition

edited by Hakan Turkkahraman

submission deadline 30 Sep 2025 | 3 articles | Viewed by 3909 | Submission Open

Keywords: artificial intelligence; machine learning; neural networks; dental diseases; clinical decision support systems; medical diagnosis

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Recent Advances in Breast Cancer Imaging

edited by

Tim Duong

submission deadline 30 Sep 2025 | 4 articles | Viewed by 3844 | Submission Open

Keywords: breast cancer; neoadjuvant chemotherapy; axillary lymph nodes; molecular subtypes; hormonal receptor positive; medical oncology; breast surgery; breast cancer metastasis; pathological complete response; breast cancer recurrence

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnosis and Management of Metabolic Bone Diseases: 2nd Edition

edited by

Patryk Lipiński

and

Anna Tylki-Szymańska

submission deadline 30 Sep 2025 | 4 articles | Viewed by 3755 | Submission Open

Keywords: inborn errors of metabolism; inherited metabolic diseases; bone metabolism/health; short stature; skeletal; disturbances in calcium and phosphorus metabolism; hypophosphatemic rickets; hypophosphatasia

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Artificial Intelligence Application in Cornea and External Diseases

edited by

Ali R. Djalilian

and Mohammad Soleimani

submission deadline 30 Sep 2025 | 2 articles | Viewed by 3371 | Submission Open

Keywords: artificial intelligence; machine learning; cornea; ocular surface; ophthalmology; external eye diseases; mobile health; telemedicine

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Recent Advancements in the Diagnostics of Prostatitis

edited by

Alberto Trinchieri

and

Florian Wagenlehner

submission deadline 30 Sep 2025 | 4 articles | Viewed by 3303 | Submission Open

Keywords: prostatitis; diagnostics; biomarkers; microbiology; imaging technologies; MRI; ultrasound; precision medicine; inflammatory proteins; genetic markers; artificial intelligence

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Integrative Approaches in Head and Neck Cancer Imaging

edited by

Calin G. Buzea

submission deadline 30 Sep 2025 | 2 articles | Viewed by 3272 | Submission Open

Keywords: head and neck cancer; imaging technologies; multimodal imaging; image-guided therapy; artificial intelligence in imaging

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Diagnosis and Management of Ophthalmic Disorders

edited by Assaf Kratz

submission deadline 30 Sep 2025 | 6 articles | Viewed by 3236 | Submission Open

Keywords: ocular diseases; early diagnosis; advanced imaging; glaucoma; age-related macular degeneration; diabetic retinopathy

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Modern Diabetes Diagnosis and Treatment Technology

edited by

Tomislav Bulum

and

Martina Tomić

submission deadline 30 Sep 2025 | 2 articles | Viewed by 3232 | Submission Open

Keywords: diabetes; complications; diagnosis; diabetic retinopathy; diabetic neuropathy; diabetic nephropathy; technology

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Latest Advances in Ophthalmic Imaging

edited by

Slawomir Teper

and

Gawęcki Maciej

submission deadline 30 Sep 2025 | 4 articles | Viewed by 3018 | Submission Open

Keywords: optical coherence tomography (OCT); adaptive optics imaging; fundus photography; multimodal imaging; artificial intelligence (AI) in ophthalmic imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

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