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Diagnostics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advancing Clinical Diagnosis with Artificial Intelligence: Applications, Challenges, and Future Directions

edited by

Haipeng Liu

Rajesh K. Tripathy

, Shonak Bansal and

Prince Jain

submission deadline 31 Mar 2026 | 7 articles | Viewed by 11348 | Submission Open

Keywords: deep learning; artificial intelligence (AI); internet of medical things (IoMT); AI-assisted diagnostics; multimodal clinical data; data-driven healthcare

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Insights into Perinatal Medicine and Fetal Medicine—2nd Edition

edited by Paola Quaresima and Ilaria Fantasia

submission deadline 31 Mar 2026 | 6 articles | Viewed by 8860 | Submission Open

Keywords: fetal malformations; hypertensive disorders of pregnancy; gestational diabetes; fetal growth; in utero surgery; first-trimester screening; fetal aneuploidies

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Insights into Pediatric Genetics

edited by

Chunglin Lee

submission deadline 31 Mar 2026 | 6 articles | Viewed by 7544 | Submission Open

Keywords: pediatric genetics; genetic sequencing; rare disorders; genetic diagnosis; precision medicine

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Cerebrovascular Lesions: Diagnosis and Management, 2nd Edition

edited by

Hung-Chieh Chen

submission deadline 31 Mar 2026 | 8 articles | Viewed by 7495 | Submission Open

Keywords: stroke; aneurysm; vascular malformation; computed tomography (CT); magnetic resonance imaging (MRI)

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advancements in Interventional Radiology Techniques in Vascular and Extravascular Diseases

edited by

Francesco Giurazza

and

Fabio Corvino

submission deadline 31 Mar 2026 | 7 articles | Viewed by 7103 | Submission Open

Keywords: embolization; radial; oncology; radioembolization; ablation; chemoembolization

(This special issue belongs to the Section Medical Imaging and Theranostics)

Recent Advances in Gynecologic Oncology: Diagnosis and Management, 2nd Edition

edited by

Jure Knez

submission deadline 31 Mar 2026 | 3 articles | Viewed by 6488 | Submission Open

Keywords: endometrial cancer; ovarian cancer; cervical cancer; vulvar cancer; ultrasound; colposcopy; diagnosis and management

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advanced Ultrasound Techniques in Diagnosis

edited by

Laith Riyadh Sultan

submission deadline 31 Mar 2026 | 5 articles | Viewed by 6146 | Submission Open

Keywords: super-resolution imaging; microvascular imaging (MVI); contrast-enhanced ultrasound; AI-guided ultrasound; quantitative analysis; diagnostic imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in the Diagnosis and Management of Musculoskeletal Diseases and Bone Fracture Risk

edited by Paola Pisani

submission deadline 31 Mar 2026 | 5 articles | Viewed by 6061 | Submission Open

Keywords: musculoskeletal diseases; bone mineral density; fracture risk; metabolic bone disorders; REMS technology

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Cardiovascular Diseases: Diagnosis and Management

edited by Hezzy Shmueli

submission deadline 31 Mar 2026 | 6 articles | Viewed by 5994 | Submission Open

Keywords: real-time imaging; cardiovascular disease; cardiovascular imaging; echocardiography; cardiac CT; cardiac MRI; cardiac nuclear scan; acute cardiac care; artificial intelligence; cardiomyopathy

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Pediatric Cardiology: Diagnosis and Management

edited by Federico Gutiérrez-Larraya

submission deadline 31 Mar 2026 | 6 articles | Viewed by 5554 | Submission Open

Keywords: pediatric cardiology; pediatric heart diseases; congenital heart disease; echocardiography; MRI

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Imaging Diagnosis of Dermatology

edited by Linda Tognetti

submission deadline 31 Mar 2026 | 4 articles | Viewed by 5254 | Submission Open

Keywords: high-resolution imaging; non-invasive diagnosis; LC-OCT; RCM; OCT; US

(This special issue belongs to the Section Medical Imaging and Theranostics)

Clinical Prognostic and Predictive Biomarkers, Third Edition

edited by

Yuli Huang

and

Peisong Chen

submission deadline 31 Mar 2026 | 3 articles | Viewed by 5059 | Submission Open

Keywords: biomarkers; prognostic; predictive; risk stratification; cardiovascular disease; diabetes; cancer; hypertension; heart failure

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Utilization of Liquid Biopsy in Cancer Diagnosis and Management 2025

edited by

Consolato M. Sergi

submission deadline 31 Mar 2026 | 3 articles | Viewed by 5025 | Submission Open

Keywords: liquid biopsy; precision medicine; cancer diagnostics; nanotechnologies; markers

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Artificial Intelligence in Diagnostics: From Algorithms to Clinical Impact

edited by

Ali Athar

, David Brown and

Hanem Ellethy

submission deadline 31 Mar 2026 | 4 articles | Viewed by 3749 | Submission Open

Keywords: machine learning in healthcare; artificial intelligence in diagnostics; medical imaging and deep learning; generative AI in medicine; multimodal data integration; explainable and trustworthy AI; translational medical AI; clinical decision support systems; secure and privacy-compliant data utilization

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances in Diagnosis and Management of Endometrial Diseases

edited by

Kotaro Kitaya

submission deadline 31 Mar 2026 | 4 articles | Viewed by 3448 | Submission Open

Keywords: endometrial diseases; artificial intelligence; hysteroscopy; ultrasound; minimally invasive surgery

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Recent Advances in Pathology 2025

edited by

Francesca Sanguedolce

and

Roberta Mazzucchelli

submission deadline 31 Mar 2026 | 1 articles | Viewed by 3424 | Submission Open

Keywords: pathology innovations; molecular diagnostics; biomarkers and precision medicine; digital pathology; artificial intelligence in pathology; translational pathology

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Hot Topics in Modern and Personalized Pathology

edited by

Sergejs Isajevs

submission deadline 31 Mar 2026 | 4 articles | Viewed by 3021 | Submission Open

Keywords: personalized diagnostics and tissue biomarkers; molecular pathology; digital pathology; oncological pathology; and rare cancer studies; tumor diagnostics and tumor biomarkers; immunohistochemistry; molecular and ultrastructural pathology; laboratory medicine

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Diagnostic Approaches to Assessing Physical Activity in Pregnancy: Monitoring Maternal Physiology and Birth Outcomes

edited by

María Mar Gil

and Aránzazu Martín-Arias

submission deadline 31 Mar 2026 | 1 articles | Viewed by 2917 | Submission Open

Keywords: diagnostics; pregnancy; maternal physiology and birth outcomes; biomarkers; prenatal care

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Functional and Structural MR Image Analysis

edited by

Xingfeng Li

submission deadline 31 Mar 2026 | 2 articles | Viewed by 2826 | Submission Open

Keywords: functional MRI; structural MRI; image analysis; radiomics; machine learning

(This special issue belongs to the Section Medical Imaging and Theranostics)

Exploring Circadian Clock Effects on Disease Diagnosis, Progression, and Therapeutic Approaches

edited by Baharan Fekry

submission deadline 31 Mar 2026 | 1 articles | Viewed by 2636 | Submission Open

Keywords: circadian clocks; circadian rhythm disorders; diagnosis; management

(This special issue belongs to the Section Clinical Laboratory Medicine)

Recent Advances in AI and Hyperspectral Techniques for Medical Imaging

edited by

Hsianmin Chen

submission deadline 31 Mar 2026 | 2 articles | Viewed by 2517 | Submission Open

Keywords: AI in medical imaging; hyperspectral medical imaging; biomedical image processing; deep learning; image segmentation and classification; multimodal imaging; intelligent diagnostic systems; tissue characterization; spectral imaging in medicine; clinical applications of AI and HSI

(This special issue belongs to the Section Medical Imaging and Theranostics)

Molecular Techniques in Infectious Disease Diagnosis: Advances and Applications

edited by

Peisong Chen

submission deadline 31 Mar 2026 | 2 articles | Viewed by 2382 | Submission Open

Keywords: molecular diagnostics; PCR; NGS; CRISPR; antimicrobial resistance; point-of-care testing; metagenomics; pathogen detection

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Artificial Intelligence in Eye Disease, 4th Edition

edited by

Jae-Ho Han

submission deadline 31 Mar 2026 | 3 articles | Viewed by 2266 | Submission Open

Keywords: medical diagnosis; artificial intelligence; deep learning; fundus image; optical coherence tomography; ophthalmology; retinal vessel; glaucoma; retinopathy; macular degeneration; image segmentation

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Molecular Diagnosis and Medical Management of Cardiovascular Diseases

edited by

Yiqing Yang

submission deadline 31 Mar 2026 | 2 articles | Viewed by 2131 | Submission Open

Keywords: cardiovascular disease; congenital heart disease; coronary artery disease; arrhythmia; cardiomyopathy; essential hypertension; stroke; molecular genetics; epidemiology; biomarkers

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Global Perspectives on Myopia—Epidemiology, Pathophysiology, and Emerging Assessment Technologies

edited by

Ungsoo-Samuel Kim

submission deadline 31 Mar 2026 | 1 articles | Viewed by 2096 | Submission Open

Keywords: myopia; diagnostic imaging; optical coherence tomography (OCT); artificial intelligence (AI); biomarkers; early detection; prevention; epidemiology; digital diagnostics

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Updates on the Diagnosis and Management of Retinal Diseases—2nd Edition

edited by

Sandra Hoyek (Alhoyek)

submission deadline 31 Mar 2026 | 2 articles | Viewed by 2077 | Submission Open

Keywords: retinal diseases; pediatric retina; Retinopathy of Prematurity (ROP); optical coherence tomography (OCT); optical coherence tomography angiography (OCTA); artificial intelligence; telemedicine; imaging biomarkers; health disparities

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

New Insights into Endoscopy-Guided Diagnosis

edited by

Haruo Miwa

submission deadline 31 Mar 2026 | 2 articles | Viewed by 2053 | Submission Open

Keywords: gastrointestinal disease; pancreatobiliary disease; magnifying endoscope; endoscopic ultrasonography; peroral cholangiopancreatography; endo-hepatology; artificial intelligence

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnosis and Management in Oral and Maxillofacial Surgery

edited by

Dimitris Tatsis

and Alexandros Louizakis

submission deadline 31 Mar 2026 | 3 articles | Viewed by 1795 | Submission Open

Keywords: oral and maxillofacial surgery; artificial intelligence in surgery; virtual surgical planning; 3D printing and patient-specific implants; oral cancer diagnosis; temporomandibular disorders; regenerative medicine in OMFS; advanced biomaterials for reconstruction; new technologies in head and neck surgery

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Endocrine System Disease: Diagnosis and Management

edited by

Kwangsoon Kim

submission deadline 31 Mar 2026 | 1 articles | Viewed by 1757 | Submission Open

Keywords: endocrine system disease; hormonal imbalance; diagnosis; hormone replacement therapy; pathophysiology

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

The Cutting Edge of Diagnosis and Treatment in Rheumatologic Disorders

edited by Ji-Hyoun Kang

submission deadline 31 Mar 2026 | 1 articles | Viewed by 1625 | Submission Open

Keywords: antiphospholipid syndrome (APS); hemolytic anemia; lupus anticoagulant; rheumatologic disorders; biomarkers

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Microbiology Laboratory: Sample Collection and Diagnosis Advances, 2nd Edition

edited by James P. Chambers and

Luke T. Daum

submission deadline 31 Mar 2026 | 1 articles | Viewed by 1502 | Submission Open

Keywords: qPCR; NGS; sample collection; nucleic acid testing; rapid antigen testing; infectious diseases; virology; sequencing; point-of-care; diagnostics; bacteriology diagnosis; biosensors

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Diagnosis in Dermatology and Venereology

edited by

Francesca Ambrogio

submission deadline 31 Mar 2026 | 1 articles | Viewed by 1477 | Submission Open

Keywords: dermatological diagnosis; venereal disease diagnosis; skin disorders; sexually transmitted infections (STIs); clinical manifestations; diagnostic techniques

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Neurofibromatosis and Schwannomatosis: Diagnosis and Management

edited by Walter Taal and Enrico Martin

submission deadline 31 Mar 2026 | 2 articles | Viewed by 1426 | Submission Open

Keywords: neurofibromatosis type 1 (NF1); neurofibromatosis type 2 (NF2); schwannomatosis (SWN); neurofibromas; schwannomas; malignant peripheral nerve sheath tumor (MPNST); glioma; tumor management; genetic counseling; quality of life (QoL)

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Artificial Intelligence in Cardiovascular and Stroke Imaging

edited by

Jasjit S. Suri

submission deadline 31 Mar 2026 | 1 articles | Viewed by 1164 | Submission Open

Keywords: artificial intelligence; cardiovascular; stroke imaging; diagnosis; prognosis

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Innovative Diagnostic Imaging Technology in Musculoskeletal Tumors

edited by

Min Wook Joo

submission deadline 31 Mar 2026 | 1 articles | Viewed by 1157 | Submission Open

Keywords: musculoskeletal tumors; diagnostic imaging; innovative technology; advanced imaging modalities; tumor classification; tumor staging; imaging protocols; image analysis techniques

(This special issue belongs to the Section Medical Imaging and Theranostics)

Applications of Machine Learning in Obstetrics and Gynecology

edited by Valentina Emilia Balas

submission deadline 31 Mar 2026 | 1 articles | Viewed by 1153 | Submission Open

Keywords: machine learning; obstetrics and gynecology; pregnancy; pregnancy-related complications; reproductive medicine

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Diagnosis and Management of Diabetes Mellitus

edited by

Franklyn Iheagwam

and

Tar-Choon Aw

submission deadline 31 Mar 2026 | 1 articles | Viewed by 958 | Submission Open

Keywords: diabetes diagnosis; glycemic monitoring; personalized treatment; chronic complications; point-of-care testing; insulin resistance; diagnostic biomarkers

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Hematologic Tumors of the Bone: From Diagnosis to Prognosis

edited by Fabio Stagno

submission deadline 31 Mar 2026 | 1 articles | Viewed by 937 | Submission Open

Keywords: bone marrow tumors; hematologic malignancies; diagnostic biomarkers; prognostic tools; targeted therapies

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnostic Imaging in Multiple Sclerosis

edited by Emanuele Tinelli

submission deadline 31 Mar 2026 | 1 articles | Viewed by 899 | Submission Open

Keywords: multiple sclerosis; MRI; neuroimaging; diagnostic imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Pediatric Ophthalmology Diagnostics and Management

edited by Mariola Dorecka and Bogumiła Wójcik-Niklewska

submission deadline 31 Mar 2026 | 1 articles | Viewed by 728 | Submission Open

Keywords: pediatric ophthalmology; children; congenital glaucoma; congenital cataract; cornea; strabismus; myopia; retinopathy of prematurity; amblyopia

(This special issue belongs to the Section Biomedical Optics)

AI-Enhanced Medical Imaging: A New Era in Oncology

edited by

Laurent Dercle

and

Laetitia Vercellino

submission deadline 31 Mar 2026 | 1 articles | Viewed by 718 | Submission Open

Keywords: AI-enhanced medical imaging; oncology; precision medicine; cancer care; image analysis; diagnostic accuracy; therapeutic planning; clinical trials; experimental validation; imaging methodologies; electromagnetic scattering; microwave imaging; combined modalities; electrical property tomography; low-frequency imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Diagnosis, Treatment and Management of Gastrointestinal Diseases

edited by

Carmen Fierbinteanu-Braticevici

submission deadline 31 Mar 2026 | 2 articles | Viewed by 669 | Submission Open

Keywords: gastrointestinal diseases; liver diseases; biomarkers in GI disease; imaging in GI diagnosis (CT; MRI; ultrasound); non-invasive diagnostic tools; GI Endoscopic procedures; treatment approaches; personalized medicine

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Biochemical Testing Applications in Clinical Diagnosis—2nd Edition

edited by

Donatella Coradduzza

submission deadline 31 Mar 2026 | 1 articles | Viewed by 640 | Submission Open

Keywords: biochemical testing; clinical diagnosis; biomarkers; point-of-care tests; innovative analytical techniques

(This special issue belongs to the Section Clinical Laboratory Medicine)

Novel Diagnostic Approaches and Personalized Interventions for Sleep Disorders

edited by Dagmara Dimitriou, Zaid Awad and Mustafa Jaafar

submission deadline 31 Mar 2026 | 1 articles | Viewed by 606 | Submission Open

Keywords: sleep disorders; obstructive sleep apnoea; diagnosis; personalized treatment; neurodivergence; comorbidities; cross-cultural sleep; wearable technology; paediatric sleep; public health

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advancing Medical Imaging with AI: From Cutting-Edge Algorithms to Clinical Integration

edited by

Kyong Joon Lee

submission deadline 31 Mar 2026 | Viewed by 524 | Submission Open

Keywords: artificial intelligence; medical imaging; deep learning; computer-aided diagnosis (CADx); diagnostic imaging; clinical validation; medical image analysis

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Detection and Characterization of Focal Lesions in the Solid Abdominal Organs

edited by

Gavin Low

submission deadline 31 Mar 2026 | 1 articles | Viewed by 477 | Submission Open

Keywords: diagnostic imaging ; disease diagnosis; detection or characterization ; multi-modality imaging ; morphologic and functional assessments

(This special issue belongs to the Section Medical Imaging and Theranostics)

Decoding Complexity in Traumatic Injury Diagnosis: Forensic Approaches

edited by

Alice Chiara Manetti

and

Fabio Del Duca

submission deadline 31 Mar 2026 | 1 articles | Viewed by 396 | Submission Open

Keywords: traumatology; forensic pathology; vitality; post-mortem examination; trauma diagnosis; forensic imaging; individual protections; job security; histology

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Acute Kidney Injury: Diagnosis and Management

edited by

Silvia De Rosa

submission deadline 31 Mar 2026 | Viewed by 347 | Submission Open

Keywords: acute kidney injury (AKI); diagnosis; renal function; biomarkers; therapeutic strategies

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

The Role of AI and Radiomics in Diagnostic Oncology

edited by Laura Travascio and

Mario Leporace

submission deadline 31 Mar 2026 | Viewed by 278 | Submission Open

Keywords: artificial intelligence; pathophysiological; radiology and nuclear medicine; diagnostic imaging; diagnostic oncology

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances in Diagnostic Cardiology

edited by Hélder Alexandre Correia Dores

submission deadline 31 Mar 2026 | Viewed by 259 | Submission Open

Keywords: cardiology; cardiac imaging; biomarkers; artificial intelligence (AI); wearable technology; precision diagnostics; point-of-care testing

(This special issue belongs to the Section Clinical Laboratory Medicine)

Displaying special issue 151-200 on page 4 of 15.

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