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Diagnostics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in Diagnostics of Chronic Kidney Disease

edited by

Tomasz Gołębiowski

and

Andrzej Konieczny

submission deadline 30 Nov 2025 | 2 articles | Viewed by 5084 | Submission Open

Keywords: chronic kidney disease; diabetic nephropathy; glomerulonephritis; acid– base disorders; uremic toxin; artificial intelligence; metabolic bone disease; vascular access; arteriovenous fistula; catheter; hemodialysis

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Echocardiography Applications in Cardiovascular Diseases

edited by

Corina Maria Vasile

submission deadline 30 Nov 2025 | 4 articles | Viewed by 4631 | Submission Open

Keywords: echocardiography; congenital heart disease; imaging techniques; artificial intelligence; automatization

(This special issue belongs to the Section Medical Imaging and Theranostics)

Medical Images Segmentation and Diagnosis

edited by

Steven L. Fernandes

submission deadline 30 Nov 2025 | 4 articles | Viewed by 4168 | Submission Open

Keywords: medical images; segmentation; diagnosis; prognosis; AI

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances in Sarcopenia: Predictive Biomarkers, Clinical Characteristics, and Therapeutic Strategies

edited by Jong Geol Do

submission deadline 30 Nov 2025 | 2 articles | Viewed by 3967 | Submission Open

Keywords: sarcopenia; predictive biomarkers; digital health technologies; interdisciplinary treatment approaches; aging population management

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Explainable Machine Learning in Clinical Diagnostics

edited by

Kai-Chih Pai

submission deadline 30 Nov 2025 | 4 articles | Viewed by 3862 | Submission Open

Keywords: interpretable machine learning (IML); explainable machine learning; clinical medicine; knowledge integration; global/local explanations

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Artificial Intelligence-Driven Radiomics in Medical Diagnosis

edited by

Shara WY Lee

submission deadline 30 Nov 2025 | 4 articles | Viewed by 3581 | Submission Open

Keywords: deep learning; convolutional neural networks (CNNs); medical imaging; diagnostic algorithms; image reconstruction; pattern recognition; predictive modelling; clinical integration; tumour identification; algorithmic transparency; image segmentation; diagnostic accuracy

(This special issue belongs to the Section Medical Imaging and Theranostics)

Ultrasound Imaging in Medicine in 2025

edited by

Michael Bachmann Nielsen

submission deadline 30 Nov 2025 | 2 articles | Viewed by 2882 | Submission Open

Keywords: 3D ultrasound; blood flow velocity; ultrasonography; contrast-enhanced ultrasound; elasticity imaging; endoscopic ultrasound; intervention

(This special issue belongs to the Section Medical Imaging and Theranostics)

Musculoskeletal Imaging 2025, 2nd Edition

edited by Parham Pezeshk

submission deadline 30 Nov 2025 | 2 articles | Viewed by 2832 | Submission Open

Keywords: imaging; radiology; diagnostic; musculoskeletal; artificial intelligence

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnostic Advances in Obstetrics and Gynecology, Breast Disease and Women’s Health

edited by Menelaos Zafrakas

submission deadline 30 Nov 2025 | 1 articles | Viewed by 2732 | Submission Open

Keywords: obstetrics; gynecology; maternal– fetal medicine; breast; women’ s health; diagnostics

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Cardiothoracic Imaging: Recent Techniques and Applications in Diagnostics, Third Edition

edited by

Giacomo Sica

and

Stefania Tamburrini

submission deadline 30 Nov 2025 | 2 articles | Viewed by 2472 | Submission Open

Keywords: emergency; cardiac imaging; thoracic imaging; aorta; MRI; CT; radiomics; artificial intelligence; ILD

(This special issue belongs to the Section Medical Imaging and Theranostics)

PET/CT Imaging in Oncology: Clinical Advances and Perspectives

edited by

Francesco Lanfranchi

submission deadline 30 Nov 2025 | 3 articles | Viewed by 2388 | Submission Open

Keywords: PET/CT imaging; molecular imaging; oncology; cancer diagnosis; precision oncology; treatment planning

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advanced Ultrasound Techniques in Diagnosis

edited by

Laith Riyadh Sultan

submission deadline 30 Nov 2025 | 2 articles | Viewed by 2290 | Submission Open

Keywords: super-resolution imaging; microvascular imaging (MVI); contrast-enhanced ultrasound; AI-guided ultrasound; quantitative analysis; diagnostic imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Application of Artificial Intelligence to Oral Diseases

edited by

Gang Li

submission deadline 30 Nov 2025 | 2 articles | Viewed by 2165 | Submission Open

Keywords: oral disease; artificial intelligence; AI-driven diagnosis; oral radiology; cone beam computed tomography (CBCT)

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

AI-Powered Solutions for Personalized Healthcare Monitoring with Wearables

edited by Kuo-Chung Chu,

Jakir Hossain Bhuiyan Masud

and Ming-Chun Huang

submission deadline 30 Nov 2025 | 2 articles | Viewed by 2153 | Submission Open

Keywords: artificial intelligence; wearable technology; health monitoring; remote patient care; personalized healthcare

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Physiological Sound Processing for Medical Diagnostics: Innovations, Challenges, and Applications

edited by

Oliver Faust

and Prabal Datta Barua

submission deadline 30 Nov 2025 | 1 articles | Viewed by 2082 | Submission Open

Keywords: heart sounds; lung sounds; cough analysis; sleep apnea and snoring; wearable devices; explainability and ethical AI; standardization and clinical validation

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Insights into Hereditary Gastrointestinal Cancer

edited by Gautam Naresh Mankaney

submission deadline 30 Nov 2025 | 1 articles | Viewed by 1955 | Submission Open

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Digital Innovation in Salivary Diagnostics for Oral and Systemic Health

edited by

Corina Marilena Cristache

submission deadline 30 Nov 2025 | 1 articles | Viewed by 1824 | Submission Open

Keywords: saliva diagnosis; oral disease; systemic diseases; artificial intelligence; AI driven diagnosis

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Paradigm Shift in the Field of Spinal Diagnosis and Treatment in 2025

edited by

Masato Tanaka

submission deadline 30 Nov 2025 | 1 articles | Viewed by 1813 | Submission Open

Keywords: artificial intelligence; mixed reality; navigation; emerging technologies (robot-assisted surgery); functional MRI; fusion images; new innovative diagnostic tools; scoliosis; adult spinal surgery; spinal tumor; spondylodiscitis; minimally invasive surgery (MIS); aging spine

(This special issue belongs to the Section Medical Imaging and Theranostics)

Bacterial Infections and Antimicrobial Resistance: Diagnosis and Management

edited by

Georgina Tzanakaki

submission deadline 30 Nov 2025 | 2 articles | Viewed by 1754 | Submission Open

Keywords: bacterial infections; antimicrobial resistance (AMR); diagnostic innovations; molecular diagnostics; antimicrobial stewardship; multidrug-resistant pathogens; alternative therapies; artificial intelligence

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Diagnosis and Prognosis of Thyroid Cancer

edited by

Chang Myeon Song

submission deadline 30 Nov 2025 | 1 articles | Viewed by 1703 | Submission Open

Keywords: thyroid cancer; diagnostic methods; prognostic tools; molecular markers; clinical outcomes; imaging

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Diagnostics Advances in Peripheral Nerve Injuries

edited by

Jean Noël Goubier

submission deadline 30 Nov 2025 | 1 articles | Viewed by 1499 | Submission Open

Keywords: peripheral nerve injuries; diagnosis challenges; magnetic resonance imaging (MRI); electromyography (EMG); brachial plexus injury; nerve trunk lesions; radicular lesions; nerve recovery assessment; advances in nerve imaging; EMG-guided treatment

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Echocardiography in the Intensive Care Unit

edited by

Carlo Caiati

submission deadline 30 Nov 2025 | 1 articles | Viewed by 1459 | Submission Open

Keywords: echocardiography; intensive care unit (ICU); critical care; cardiac function; coronary artery disease; sepsis; shock

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnostic Imaging of Autoimmune Diseases

edited by Simone Appenzeller

submission deadline 30 Nov 2025 | 1 articles | Viewed by 1380 | Submission Open

Keywords: autoimmune diseases; systemic lupus erythematosus; systemic sclerosis; diagnosis; imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

New Advances in Thoracic Surgery: Clinical Diagnosis, Treatment, and Prognosis—2nd Edition

edited by

Stefano Elia

submission deadline 30 Nov 2025 | 2 articles | Viewed by 1009 | Submission Open

Keywords: thoracic surgery; lung cancer; pleural diseases; mediastinal malignancies; surgical outcome

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

AI and Big Data in Medical Diagnostics

edited by

Miguel Mascarenhas

, Hélder Cardoso and

Guilherme Macedo

submission deadline 30 Nov 2025 | 2 articles | Viewed by 977 | Submission Open

Keywords: artificial intelligence; big data; diagnosis; convolutional neural networks; precision medicine

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Functional and Structural MR Image Analysis

edited by

Xingfeng Li

submission deadline 30 Nov 2025 | 1 articles | Viewed by 892 | Submission Open

Keywords: functional MRI; structural MRI; image analysis; radiomics; machine learning

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in the Application of Ultrasound Technology in the Diagnosis of Skin Diseases

edited by

Priscila Giavedoni

submission deadline 30 Nov 2025 | 1 articles | Viewed by 850 | Submission Open

Keywords: skin ultrasound; cutaneous imaging; inflammatory skin diseases; skin tumors; high-frequency ultrasound; diagnostic imaging; medical imaging; ultrasound-guided procedures; dermatology; skin assessment

(This special issue belongs to the Section Medical Imaging and Theranostics)

Theragnostic Applications of Nanotechnologies

edited by

Viviana Frantellizzi

Giuseppe De Vincentis

and Maria Silvia De Feo

submission deadline 30 Nov 2025 | Viewed by 368 | Submission Open

Keywords: nanotechnologies; theragnostics; nuclear medicine; personalized therapy; CT; MRI; radionuclides; nanoparticles; PET

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Diagnosis of Ovarian Cancer

edited by

Samrita Dogra

submission deadline 30 Nov 2025 | Viewed by 350 | Submission Open

Keywords: ovarian cancer diagnosis; early detection; biomarkers; molecular diagnostics; imaging technologies; precision medicine; innovative methods; treatment monitoring; prognosis assessment

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in Surgical Pathology—Dedicated to Professor Janez Plecnik

edited by

Cesar A. Moran

submission deadline 30 Nov 2025 | Viewed by 338 | Submission Open

Keywords: tumor; immunohistochemistry; molecular pathology; oncology; thorax; gastrointestinal; gynecological; dermatopathology/soft tissue pathology

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in Hematology Laboratory—2nd Edition

edited by

Eloisa Urrechaga

submission deadline 30 Nov 2025 | Viewed by 254 | Submission Open

Keywords: complete blood counts; leukocyte differential; reticulocyte indices; immature platelet fraction; cell population data; blood cell analyzers

(This special issue belongs to the Section Clinical Laboratory Medicine)

Advances in Diagnostic Techniques and Endoscopic Management for Gastrointestinal Diseases

edited by

Micheal Tadros

submission deadline 30 Nov 2025 | Viewed by 248 | Submission Open

Keywords: endoscopy; gastrointestinal disease; diagnostic techniques

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Optical Imaging in Dermatology

edited by

Victor Desmond Mandel

submission deadline 30 Nov 2025 | Viewed by 246 | Submission Open

Keywords: optical imaging; dermatology; reflectance confocal microscopy; optical coherence tomography; multiphoton microscopy; Raman spectroscopy; super-resolution microscopy; hyperspectral imaging

(This special issue belongs to the Section Biomedical Optics)

Early Diagnosis of Sepsis: Current Status and Challenges

edited by

Andrea Piccioni

and

Gloria Rozzi

submission deadline 30 Nov 2025 | Viewed by 229 | Submission Open

Keywords: sepsis; early diagnosis of sepsis; biomarkers; sepsis mortality; serum presepsin; SOFA score

(This special issue belongs to the Section Clinical Laboratory Medicine)

Advances in Diagnosis and Management in Pediatric Neuro-Oncology

edited by Mandana Behbahani and Allison M. Martin

submission deadline 30 Nov 2025 | Viewed by 212 | Submission Open

Keywords: pediatric neurosurgery; pediatric neuro-oncology; neuroendoscopy; epilepsy; pediatric brain tumor; hydrocephalus treatment

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Laboratory Diagnosis of Infections

edited by Mònica Balaguer Gargallo

submission deadline 30 Nov 2025 | Viewed by 210 | Submission Open

Keywords: infections; laboratory diagnosis; biochemical markers; bacterial resistance

(This special issue belongs to the Section Clinical Laboratory Medicine)

Diagnosis and Treatment of Kidney Disease—2nd Edition

edited by

Giuseppe Stefano Netti

submission deadline 30 Nov 2025 | Viewed by 177 | Submission Open

Keywords: kidney diseases; acute kidney injury; nephropathy; biomarkers; diagnosis; chronic renal failure

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Soft Tissue and Bone Sarcomas: Advances in Diagnosis, Treatment, and Prognosis

edited by

Andrea Angelini

submission deadline 30 Nov 2025 | Viewed by 169 | Submission Open

Keywords: soft tissue sarcomas; bone sarcomas; diagnosis; prognosis; biomarkers

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Imaging in Oral Diseases

edited by Xavier Roselló-LLabres and

José López López

submission deadline 30 Nov 2025 | Viewed by 155 | Submission Open

Keywords: CBCT 3D maxillofacial imaging; virtual diagnostic simulation; social media pathology image sharing; oral disease diagnostic algorithms; AI-driven oral pathology detection; dental radiographic caries analysis; digital oral lesion segmentation; cross-disciplinary imaging workflows; tele-radiology collaboration platforms; salivary gland scintigraphy applications

(This special issue belongs to the Section Medical Imaging and Theranostics)

Clinical Diagnosis and Prognosis of Steatotic Liver Disease

edited by

Helma Pinchemel Cotrim

submission deadline 30 Nov 2025 | Viewed by 154 | Submission Open

Keywords: steatotic liver disease— SLD; steatohepatitis; steatosis; diagnosis; prognosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Novel Optical Imaging Technologies in Ophthalmology and Neuroscience: Advances and Applications

edited by

Jae-Ho Han

submission deadline 30 Nov 2025 | Viewed by 151 | Submission Open

Keywords: optical imaging; ophthalmology; neuroscience; diagnosis; prognosis

(This special issue belongs to the Section Biomedical Optics)

Hepatocellular Carcinoma: Diagnosis and Management

edited by Po-Ming Chen

submission deadline 30 Nov 2025 | Viewed by 148 | Submission Open

Keywords: hepatocellular carcinoma; chronic infection; non-alcoholic steatohepatitis; diagnostic and therapeutic strategies

(This special issue belongs to the Section Medical Imaging and Theranostics)

Artificial Intelligence in Hearing Diseases

edited by

Mehdi Abouzari

submission deadline 30 Nov 2025 | Viewed by 146 | Submission Open

Keywords: artificial intelligence; hearing loss; diagnosis; machine learning; auditory neuroscience; speech recognition; cochlear implants; data science; computational algorithm

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Current Status and Challenges of Heart Disease Diagnosis

edited by

Giuseppe Sgarito

submission deadline 30 Nov 2025 | Viewed by 138 | Submission Open

Keywords: heart disease; cardiovascular diagnosis; cardiac imaging; artificial intelligence; biomarkers; end-stage heart failure; electrophysiology; sudden cardiac death; tissue characterization; personalized medicine

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Revolutionizing Male Infertility: Novel Mechanistic Insights, Diagnostic Innovations, and Management Strategies

edited by

Athanasios Zachariou

submission deadline 30 Nov 2025 | Viewed by 136 | Submission Open

Keywords: male infertility; andrology; reproductive health; testis; spermatozoa; semen analysis; TESE; mTESE; ultrasound; artificial intelligence; IVF

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Imaging for Kidney Disease: Innovations in Diagnosis and Monitoring

edited by Abhilash Koratala

submission deadline 30 Nov 2025 | Viewed by 129 | Submission Open

Keywords: renal imaging; ultrasound innovations; precision diagnostics

(This special issue belongs to the Section Medical Imaging and Theranostics)

Latest Innovations in Interventional Oncology

edited by

Pierleone Lucatelli

and

David C. Madoff

submission deadline 30 Nov 2025 | Viewed by 124 | Submission Open

Keywords: contrast-enhanced ultrasound (CEUS); hybrid PET-MRI oncology imaging; optical coherence tomography (OCT) diagnostics; AI-driven lesion segmentation; radiomics-based tumor profiling; liquid biopsy innovations; endovascular biomarker sampling; molecular imaging specificity; real-time tumor characterization; image-guided diagnostic paradigms

(This special issue belongs to the Section Medical Imaging and Theranostics)

Current Diagnosis and Treatment in Surgical Oncology

edited by Spiros G. Delis

submission deadline 30 Nov 2025 | Viewed by 114 | Submission Open

Keywords: diagnosis; surgical oncology; surgical techniques; medical imaging; personalized medicine

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Recent Advances in the Diagnosis and Prognosis of Lung Cancer

edited by Naomi Takemura

submission deadline 10 Dec 2025 | Viewed by 128 | Submission Open

Keywords: lung cancer; molecular biomarkers; artificial intelligence; early detection; precision detection; medical imaging

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Tuberculosis Detection and Diagnosis 2025

edited by

Kanagavel Murugesan

submission deadline 30 Dec 2025 | 3 articles | Viewed by 5493 | Submission Open

Keywords: immunological testing: TST; IGRA; microscopic testing: sputum smear microscopy; AFB staining; molecular testing: NAATs; including LAMP and GeneXpert MTB/RIF; fluorescence in situ hybridization (FISH); culture-based testing: BACTEC MGIT; imaging techniques: X-rays; CT; advanced testing technologies: NGS; mass spectrometry

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

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