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Diagnostics
Special Issues
Diagnosis and Management of Thoracic Diseases
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Diagnosis and Management of Thoracic Diseases

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Pathology and Molecular Diagnostics".

Deadline for manuscript submissions: 30 April 2025 | Viewed by 1139

Special Issue Editor

Dr. Ke-Cheng Chen

E-Mail Website
Guest Editor
Department of Surgery, National Taiwan University Hospital, Taipei 100, Taiwan
Interests: thoracic diseases; diagnosis; treatment; lung tumor; thoracoscopy; biomarker; prognosis

Special Issue Information

Dear Colleagues,

Thoracic diseases are common and important health issues. Infectious diseases like COVID-19 and thoracic malignancies belong to this particular disease category. Millions of people are affected by thoracic diseases around the world, and the number continues to rise without doubt. To deal with these diseases, scientists and clinicians are inventing novel treatments including different diagnostic tools and drugs, as well as new interventional technology. Therefore, in this Special Issue, we aim to collect articles focusing on cutting-edge diagnostic tools and new therapies for thoracic diseases. Moreover, exploring biomarkers and disease screening/prognoses also falls within our scope and interests. With this Special Issue, we aim to improve our knowledge and strengthen our faith, fighting back against health-threatening thoracic diseases.

Dr. Ke-Cheng Chen
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • thoracic diseases
  • lung
  • diagnosis
  • treatment
  • lung tumor
  • thoracoscopy
  • biomarker
  • prognosis

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (2 papers)

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Research

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20 pages, 998 KiB  
Article
Surviving COVID-19 and Battling Fibrosis: A Retrospective Cohort Study Across Three Pandemic Waves
by Mihai Lazar, Ecaterina Constanta Barbu, Cristina Emilia Chitu, Mihaela Buzoianu, Andreea Catalina Petre, Catalin Tiliscan, Stefan Sorin Arama, Victoria Arama, Daniela Adriana Ion and Mihaela Cristina Olariu
Diagnostics 2024, 14(24), 2811; https://doi.org/10.3390/diagnostics14242811 - 13 Dec 2024
Cited by 1 | Viewed by 873
Abstract
Background/Objectives: We aimed to characterize the fibrosis following COVID-19 pneumonia, using quantitative analysis, after three months and subsequently, after two years of patients’ release from the hospital, and to identify the risk factors for pulmonary fibrosis. Methods: We performed a retrospective, observational cohort [...] Read more.
Background/Objectives: We aimed to characterize the fibrosis following COVID-19 pneumonia, using quantitative analysis, after three months and subsequently, after two years of patients’ release from the hospital, and to identify the risk factors for pulmonary fibrosis. Methods: We performed a retrospective, observational cohort study on 420 patients with severe forms of COVID-19. For all patients, we registered demographic, inflammatory and biochemical parameters, complete blood count and D-dimers; all patients underwent three computed tomography scans (at admittance, at 3 months and at 2 years). Results: We found fibrosis in 67.9% of patients at the 3-month evaluation and in 42.4% of patients at the 2-year evaluation, registering a significant decrease in the severe and moderate fibrosis cases, with a slight increase in the mild fibrosis cases. The risk of fibrosis was found to be proportional to the values of age, duration of hospital stay, inflammatory markers (ESR, fibrinogen), cytolytic markers (LDH, AST) and D-dimers. The highest correlations with lung fibrosis were registered for interstitial pulmonary involvement (for the 3-month evaluation) and total pulmonary involvement (for the 2-year evaluation). Conclusions: Lung fibrosis represents a significant post-COVID-19 complication found in 42% of patients with severe forms of pneumonia at the 2-year evaluation. A significant overall decrease in the severity of lung fibrosis was registered at the 2-year evaluation compared to the 3-month evaluation. We consider that the amount of interstitial pulmonary involvement represents the optimal parameter to estimate the risk of lung fibrosis following SARS-CoV-2 pneumonia. Full article
(This article belongs to the Special Issue Diagnosis and Management of Thoracic Diseases)
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11 pages, 3098 KiB  
Case Report
Vertebral Metastasis in a Bronchial Carcinoid: A Rare Case Report with More than 3-Year Follow-Up and Review of the Literature
by Carlo Biz, Maria Grazia Rodà, Fabiana Mori, Lorenzo Costa, Joseph Domenico Gabrieli, Francesco Causin and Pietro Ruggieri
Diagnostics 2025, 15(9), 1128; https://doi.org/10.3390/diagnostics15091128 - 28 Apr 2025
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Abstract
Background: Skeletal metastases from carcinoid tumours are extremely rare. Their correct diagnosis is a challenging problem for clinicians and pathologists, with important clinical implications for patients. In most cases, examination for the possible presence of skeletal metastases is initiated only when patients present [...] Read more.
Background: Skeletal metastases from carcinoid tumours are extremely rare. Their correct diagnosis is a challenging problem for clinicians and pathologists, with important clinical implications for patients. In most cases, examination for the possible presence of skeletal metastases is initiated only when patients present symptoms suggestive of skeletal metastases. Case presentation: In this paper, the authors present the case of a middle-aged woman suffering from back pain due to a bronchial carcinoid that metastasised to the spine. We managed skeletal metastases with vertebroplasty and achieved excellent results and the complete remission of symptoms six months after the procedure. Conclusions: The relevance of this case report is that it highlights the importance of correctly diagnosing and treating these rare lesions to improve the quality of life of metastatic oncologic patients. Full article
(This article belongs to the Special Issue Diagnosis and Management of Thoracic Diseases)
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