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Diagnostics
Special Issues
Diagnosis and Management in Digestive Surgery: 2nd Edition
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Diagnosis and Management in Digestive Surgery: 2nd Edition

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Pathology and Molecular Diagnostics".

Deadline for manuscript submissions: 31 October 2025 | Viewed by 592

Special Issue Editors

Dr. Valentin Calu

E-Mail Website
Guest Editor
Assoc. Prof., Department of General Surgery, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
Interests: surgical oncology; laparoscopic surgery; colorectal surgery
Special Issues, Collections and Topics in MDPI journals
Dr. Florin Grama

E-Mail Website
Guest Editor
Assoc. Prof., Department of General Surgery, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
Interests: surgical oncology; laparoscopic surgery; colorectal surgery
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue is intended to serve as an opportunity to provide an update in terms of the diagnosis and management of digestive diseases. We have all witnessed to some extent the technical and technological development within the medical field. Nevertheless, due to rapid changes, self-actualization can be occasionally strenuous. The methods of diagnosis but also management have undergone serious modifications with the passage of time, hence the utility of this Special Issue. Whether we are talking about improved precision when determining the type of pathology or tailored multidisciplinary treatment, the field of digestive diseases is in constant change. Interesting diagnoses or fascinating management techniques can be submitted as an article for publication. Research articles, review articles, and special case reports are invited.

Dr. Valentin Calu
Dr. Florin Grama
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • digestive diseases
  • novel changes in diagnosis
  • updates on daily practice
  • management of digestive diseases

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Further information on MDPI's Special Issue policies can be found here.

Related Special Issue

Published Papers (1 paper)

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Review

16 pages, 1162 KiB  
Review
Ultrasound for the Early Detection and Diagnosis of Necrotizing Enterocolitis: A Scoping Review of Emerging Evidence
by Indrani Bhattacharjee, Michael Todd Dolinger, Rachana Singh and Yogen Singh
Diagnostics 2025, 15(15), 1852; https://doi.org/10.3390/diagnostics15151852 - 23 Jul 2025
Viewed by 227
Abstract
Background: Necrotizing enterocolitis (NEC) is a severe gastrointestinal disease and a major cause of morbidity and mortality among preterm infants. Traditional diagnostic methods such as abdominal radiography have limited sensitivity in early disease stages, prompting interest in bowel ultrasound (BUS) as a complementary [...] Read more.
Background: Necrotizing enterocolitis (NEC) is a severe gastrointestinal disease and a major cause of morbidity and mortality among preterm infants. Traditional diagnostic methods such as abdominal radiography have limited sensitivity in early disease stages, prompting interest in bowel ultrasound (BUS) as a complementary imaging modality. Objective: This scoping review aims to synthesize existing literature on the role of ultra sound in the early detection, diagnosis, and management of NEC, with emphasis on its diagnostic performance, integration into clinical care, and technological innovations. Methods: Following PRISMA-ScR guidelines, a systematic search was conducted across PubMed, Embase, Cochrane Library, and Google Scholar for studies published between January 2000 and December 2025. Inclusion criteria encompassed original research, reviews, and clinical studies evaluating the use of bowel, intestinal, or Doppler ultrasound in neonates with suspected or confirmed NEC. Data were extracted, categorized by study design, population characteristics, ultrasound features, and diagnostic outcomes, and qualitatively synthesized. Results: A total of 101 studies were included. BUS demonstrated superior sensitivity over radiography in detecting early features of NEC, including bowel wall thickening, portal venous gas, and altered peristalsis. Doppler ultrasound, both antenatal and postnatal, was effective in identifying perfusion deficits predictive of NEC onset. Neonatologist-performed ultrasound (NEOBUS) showed high interobserver agreement when standardized protocols were used. Emerging tools such as ultra-high-frequency ultrasound (UHFUS) and artificial intelligence (AI)-enhanced analysis hold potential to improve diagnostic precision. Point-of-care ultrasound (POCUS) appears feasible in resource-limited settings, though implementation barriers remain. Conclusions: Bowel ultrasound is a valuable adjunct to conventional imaging in NEC diagnosis. Standardized protocols, validation of advanced technologies, and out come-based studies are essential to guide its broader clinical adoption. Full article
(This article belongs to the Special Issue Diagnosis and Management in Digestive Surgery: 2nd Edition)
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