New Advances in Diagnostic Bronchoscopy

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Biomedical Optics".

Deadline for manuscript submissions: 31 October 2025 | Viewed by 491

Special Issue Editor


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Guest Editor
Interventional Pulmonology Section, Department of Medicine, Westchester Medical Center, New York Medical College, Valhalla, NY 10595, USA
Interests: bronchoscopy; transbronchial; endobronchial
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Special Issue Information

Dear Colleagues,

This Special Issue will provide an overview of the latest developments in the field of diagnostic bronchoscopy. The featured articles will address the introduction of advanced imaging techniques, such as three-dimensional reconstruction and real-time virtual bronchoscopy, which have significantly improved the accuracy and safety of bronchoscopic procedures, as well as discussing the role of artificial intelligence in enhancing diagnostic capabilities, including the use of machine learning algorithms to detect subtle abnormalities. Furthermore, articles will explore advancements in interventional bronchoscopy, with a focus on minimally invasive techniques that reduce patient discomfort and recovery times. Overall, the advancements discussed in these articles will demonstrate the continued evolution of diagnostic bronchoscopy, benefiting both patients and healthcare providers.

Dr. Kassem Harris
Guest Editor

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Keywords

  • diagnostic bronchoscopy
  • advanced imaging techniques
  • interventional bronchoscopy
  • minimally invasive techniques

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Published Papers (1 paper)

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Research

11 pages, 924 KiB  
Article
Radial-Probe Endobronchial Ultrasound as Part of Different Navigational Bronchoscopy Modalities in Combination with Cryobiopsy Could Be More than a Confirmation Tool: A Case Series
by Nevenka Piskac Zivkovic, Maja Karaman Ilic, Suncana Divosevic, Hrvoje Feljan, Igor Nikolic, Zrinka Juros, Ana-Marija Sola, Sven Seiwerth, Dragan Schwarz and Ivica Mazuranic
Diagnostics 2025, 15(15), 1884; https://doi.org/10.3390/diagnostics15151884 - 27 Jul 2025
Viewed by 338
Abstract
Background: As part of different navigational bronchoscopy (NVB) modalities, radial-probe endobronchial ultrasound (rEBUS) is used to confirm the peribronchial localization of peripheral pulmonary nodules (PPNs) immediately before collecting samples for histopathological analysis. Methods: This retrospective case series study presents the results [...] Read more.
Background: As part of different navigational bronchoscopy (NVB) modalities, radial-probe endobronchial ultrasound (rEBUS) is used to confirm the peribronchial localization of peripheral pulmonary nodules (PPNs) immediately before collecting samples for histopathological analysis. Methods: This retrospective case series study presents the results of en bloc cryobiopsy of PPNs using a flexible 1.1-mm cryoprobe with different NVB modalities. For PPNs classified as adjacent or eccentric lesions by rEBUS (ES-rEBUS), the cryoprobe’s position was adjusted by 90–180° in relation to the ultrasound image of the lesion during the first and second biopsies. Results: All patients with a final histopathologically confirmed diagnosis of PPNs had positive rEBUS findings, regardless of the navigation modality, eccentric (18/42 patients, 43%) and concentric (24/42 patients, 57%) rEBUS view. In 5 out of 6 patients without a histopathological diagnosis, PPNs were not visualized by radial ultrasound. In the (ES-rEBUS) group of patients, 4 out of 18 had fewer than three biopsy samples collected per procedure, which means only an adjusted probe position has been applied, although diagnostic outcomes were achieved. Common Terminology Criteria for Adverse Events (CTCAE) grade 2 complications were reported in 10.4% of the patients, and grade 3 complications in 2% of the patients. Conclusions: Confirming the localization of nodules by rEBUS and properly adjusting the cryoprobe immediately before cryobiopsy of PPNs resulted in a diagnostic yield meeting the literature standards. Full article
(This article belongs to the Special Issue New Advances in Diagnostic Bronchoscopy)
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