Cellular and Molecular Players in Bone Homeostasis
A special issue of Cells (ISSN 2073-4409).
Deadline for manuscript submissions: 1 August 2025 | Viewed by 56
Special Issue Editor
2. Deutsches Zentrum für Immuntherapie (DZI), 91054 Erlangen, Germany
Interests: osteoimmunology; autoimmune diseases; bone
Special Issue Information
Dear Colleagues,
The Special Issue “Cellular and Molecular Players in Bone Homeostasis” aims to provide a comprehensive exploration of the intricate cellular and molecular mechanisms governing bone health and stability. This Issue invites original research and review articles that focus on the diverse cell populations found in bone, including skeletal stem cells, osteoblasts, osteocytes, osteoclasts, and adipocytes, and the molecular factors regulating their function. Special attention will be given to the roles of microenvironmental factors such as immune cells, stromal cells, blood supply (hypoxia), and energy metabolism in shaping bone homeostasis. We also welcome studies addressing how disruptions in these tightly regulated systems contribute to bone-related diseases such as fractures, osteoporosis, arthritis, and bone cancers. Manuscripts investigating the cross-talk between bone cells and their microenvironment, the impact of systemic conditions, and novel therapeutic targets are particularly encouraged. This Special Issue seeks to highlight cutting-edge research and foster a deeper understanding of the dynamic balance required to maintain bone integrity, as well as the pathological processes that lead to its breakdown. By bridging molecular, cellular, and translational insights, this Issue aims to advance the field of bone biology and inspire future innovations in disease management and therapy.
Dr. Darja Andreev
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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Keywords
- bone homeostasis
- cellular and molecular mechanisms
- bone-related diseases
- microenvironmental factors
- therapeutic targets
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