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Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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New Insights into Thymic Tumors
edited by Till Ploenes
submission deadline 15 Jan 2027 | 2 articles | Viewed by 2097 | Submission Open
Keywords: thymic tumors; thymic carcinoma; thymomas; new daignostic and therapeutic approaches; myasthenia gravis
Nanocarriers as an Emerging Platform for Cancer Therapy
edited by and Fernanda Ramos-Gomes
submission deadline 15 Jan 2027 | 2 articles | Viewed by 1801 | Submission Open
Keywords: nanoparticles; cancer therapy; nanomedicine; theranostics; chemotherapy; nanocarriers; drug delivery; nanotechnology
(This special issue belongs to the Section Cancer Therapy)
Flow Cytometry in Acute Leukemia: From Diagnosis to Disease Monitoring submission deadline 15 Jan 2027 | 2 articles | Viewed by 1626 | Submission Open
Keywords: acute leukemia; ALL; AML; flow cytometry; NGF; leukemia stem cells (LSCs; minimal residual disease (MRD)
(This special issue belongs to the Section Methods and Technologies Development)
Mass Spectrometry and Cancers submission deadline 15 Jan 2027 | 1 articles | Viewed by 996 | Submission Open
Keywords: cancer; biomolecular; mass spectrometry
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
Advancing CAR-T Cell Therapy: The Next Evolution in Breast Cancer Treatment submission deadline 15 Jan 2027 | Viewed by 912 | Submission Open
Keywords: CAR-T cell therapy; breast cancer; triple-negative breast cancer (TNBC); HER2-positive breast cancer; tumor microenvironment; immunotherapy
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Three-Dimensional In Vitro Modeling for the Study of Epithelial Cancers
edited by and George Wai Cheong Yip
submission deadline 15 Jan 2027 | Viewed by 488 | Submission Open
Keywords: 3D cancer model; 3D cancer stem cell culture; 3D tumor invasion model; cancer-on-a-chip; cancer spheroids; carcinogenesis organoid model; bioprinted cancer tissue; microfluidic platform for cancer; scaffold-based cancer model
(This special issue belongs to the Section Methods and Technologies Development)
AI and Machine Learning in Cancer Multi-Omics: Identification of Biomarkers, Disease-Related Processes and Drug Targets
edited by Graham Ball
submission deadline 15 Jan 2027 | Viewed by 416 | Submission Open
Keywords: artificial intelligence; machine learning; multi-omics integration; biomarker discovery; precision oncology; drug target identification; computational cancer biology
(This special issue belongs to the Section Methods and Technologies Development)
Pancreatic Cancer: Genomics, Therapy and Survival
edited by Hisanobu Ogata
submission deadline 15 Jan 2027 | Viewed by 369 | Submission Open
Keywords: pancreas; cancer; treatment; oncolytic virus; stromal cell; cancer-associated fibroblast (CAF)
(This special issue belongs to the Section Cancer Therapy)
Radiotherapy in Gynecological Cancer: State of the Art (2nd Edition) submission deadline 15 Jan 2027 | Viewed by 259 | Submission Open
Keywords: interventional radiotherapy; brachytherapy techniques; gynecological oncology; educational gynecology; gynecological cancer
(This special issue belongs to the Section Cancer Therapy)
Improving the Quality of Life in Patients with Gynecological Cancer
edited by Vasilios Pergialiotis
submission deadline 20 Jan 2027 | 2 articles | Viewed by 14422 | Submission Open
Keywords: gynecologic oncology; minimal invasive surgery; ovarian cancer; ERAS protocol; perioperative care; immunonutrition; cervical cancer
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Feature Review Papers on Cancer Epidemiology, Disparities, and Prevention
edited by Adam Barsouk
submission deadline 20 Jan 2027 | 2 articles | Viewed by 3936 | Submission Open
Keywords: epidemiology; disparities; oncology; cancer; prevention
(This special issue belongs to the Section Cancer Epidemiology and Prevention)
Advances in Molecules and Drug Delivery Systems in Brain Tumors
edited by Horng-Jyh Harn and Ching-Ann Liu
submission deadline 27 Jan 2027 | Viewed by 101 | Submission Open
Keywords: brain tumors; blood–brain barrier; drug delivery systems; nanoparticles; molecular targets; targeted therapy; nanomedicine; combination therapy; translational research; biomarkers
(This special issue belongs to the Section Cancer Drug Development)
Advances in Clinical Therapy and Prognosis of Gastrointestinal Cancer
edited by Liliana Streba and Michael Schenker
submission deadline 30 Jan 2027 | 6 articles | Viewed by 9545 | Submission Open
Keywords: gastrointestinal cancer; tumorigenesis; microbiome; early detection; molecular mechanisms; personalized medicine; novel therapeutics; translational research; clinical application; diagnostic innovations
(This special issue belongs to the Section Clinical Research in Cancer)
Genetic Determinism and Singularity: Fundamentals of Genomic, Predictive and Personalized Medicine of Thyroid Cancer
edited by Ginesa Maria Garcia-Rostan
submission deadline 30 Jan 2027 | Viewed by 179 | Submission Open
Keywords: screening; molecular pathogenesis; metastases; progression; dedifferentiation; prognostic biomarkers; targeted therapies; molecular heterogeneity and therapy resistance; follicular-cell-derived thyroid carcinomas; C-cell-derived thyroid carcinomas
Circulating Tumor DNA in Solid Tumors
edited by and Xiao Han
submission deadline 30 Jan 2027 | Viewed by 160 | Submission Open
Keywords: circulating tumor DNA; liquid biopsy; precision oncology
(This special issue belongs to the Section Cancer Biomarkers)
Lymphoma: From Pathology to Clinical Applications
edited by Eduardo M. Sotomayor and
submission deadline 30 Jan 2027 | Viewed by 93 | Submission Open
Keywords: lymphoma; next-generation sequencing; molecular subtypes; measurable residual disease; cellular therapy; precision medicine
New Perspectives in the Management of Breast Cancer submission deadline 31 Jan 2027 | 15 articles | Viewed by 47769 | Submission Open
Keywords: breast cancer; treatment; nutrition; physical exercise; psychosocial impact
(This special issue belongs to the Section Cancer Therapy)
Clinical Trials and Outcomes for Non-Small Cell Lung Cancer submission deadline 31 Jan 2027 | 8 articles | Viewed by 12623 | Submission Open
Keywords: non-small cell lung cancer; oncogenic alterations; clinical trial; systemic therapy; targeted therapy; immunotherapy; radiotherapy; real-world data; surgery; drug development
(This special issue belongs to the Section Clinical Research in Cancer)
The Future of Cancer Immunotherapy: Biomarkers, Tumor Microenvironment, and Precision Medicine
edited by Aftab Alam
submission deadline 31 Jan 2027 | 5 articles | Viewed by 9654 | Submission Open
Keywords: immunotherapy; genomics; proteomics checkpoint; CAR T cells; predictive biomarkers; resistance mechanisms; combination approaches; tumor microenvironment
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Recent Advances in Liquid Biopsy Biomarkers of Cancer
edited by
submission deadline 31 Jan 2027 | 6 articles | Viewed by 9439 | Submission Open
Keywords: liquid biopsy; circulating tumor cells; circulating tumor DNA; extracellular vesicles; circulating RNA; cfDNA methylation; fragmentome; reference material; miRNA; multi-cancer detection
(This special issue belongs to the Section Cancer Biomarkers)
Novel Treatments for Ocular and Periocular Cancers
edited by
submission deadline 31 Jan 2027 | 4 articles | Viewed by 8986 | Submission Open
Keywords: ocular cancer; intraocular tumor; retinoblastoma; uveal melanoma
(This special issue belongs to the Section Cancer Therapy)
Innovations in Microsurgical Techniques for Breast Cancer Reconstruction
edited by and Robert J. Allen
submission deadline 31 Jan 2027 | 5 articles | Viewed by 8701 | Submission Open
Keywords: breast reconstruction; autologous breast reconstruction; DIEP flap; robotic DIEP flap; sensibility; alternative flaps; post-mastectomy pain; PAP flap; LAP flap; GAP flap; LTP flap; perforator flap; latissimus flap; fat grafting; nerve repair
(This special issue belongs to the Section Methods and Technologies Development)
CT/MRI/PET in Cancer submission deadline 31 Jan 2027 | 5 articles | Viewed by 7929 | Submission Open
Keywords: PET imaging; CT; MRI; cancer; characterization; treatment monitoring; biomarkers; predictive value; AI integration
(This special issue belongs to the Section Methods and Technologies Development)
Precision Medicine and Targeted Therapies in Neuroblastoma
edited by
submission deadline 31 Jan 2027 | 3 articles | Viewed by 7496 | Submission Open
Keywords: pediatric oncology; solid tumors; targeted therapies; biomarkers of response; novel combination therapies; tumor microenvironment; integrative diagnostics; theranostics; telomere maintenance mechanisms; neuroblastoma
(This special issue belongs to the Section Clinical Research in Cancer)
Lung Cancer: Diagnosis and Targeted Therapy submission deadline 31 Jan 2027 | 4 articles | Viewed by 4514 | Submission Open
Keywords: lung cancer; modern diagnostics; screening; imaging; pathologic and molecular profiling; biomarkers; targeted therapies; next-generation TKIs; antibody–drug conjugates (ADCs); drug resistance
Multidisciplinary Approach to Bladder Cancer Treatment and Care
edited by Bente Thoft Jensen and
submission deadline 31 Jan 2027 | 4 articles | Viewed by 4312 | Submission Open
Keywords: non-muscle-invasive bladder cancer; muscle-invasive bladder cancer; health-related quality of life; nutrition; prehabilitation; sexual health; nursing leadership; implementation; new technologies
(This special issue belongs to the Section Cancer Therapy)
Plasma and Cancer Treatment
edited by and
submission deadline 31 Jan 2027 | 2 articles | Viewed by 4292 | Submission Open
Keywords: cold atmospheric plasma (CAP); cancer treatment; plasma medicine; reactive oxygen species (ROS); apoptosis; tumor; non-thermal plasma; plasma oncology; cancer and molecular biology; clinical translation; in vivo/preclinical
(This special issue belongs to the Section Cancer Therapy)
Advances in the Use of PET/CT and MRI in Prostate Cancer: 2nd Edition
edited by
submission deadline 31 Jan 2027 | 3 articles | Viewed by 3802 | Submission Open
Keywords: PET/CT; MRI; prostate cancer; radiomic; receptor-targeted radiopharmaceuticals
(This special issue belongs to the Section Methods and Technologies Development)
Innovations in Active Surveillance Management of Early Prostate Cancer submission deadline 31 Jan 2027 | 2 articles | Viewed by 3592 | Submission Open
Keywords: prostate cancer; risk stratification; active surveillance; predictive markers; personalized management; imaging; biomarkers; clinical pathways; patient outcomes; standardizing care; attrition; cohort studies
(This special issue belongs to the Section Cancer Epidemiology and Prevention)
Liquid Biopsy Technology Development and Clinical Applications in Cancer Research and Treatment
edited by and Xia Yu
submission deadline 31 Jan 2027 | 3 articles | Viewed by 3008 | Submission Open
Keywords: liquid biopsy; biomarkers; circulating tumor cells; circulating nucleic acids; extracellular vesicles; proteins; cancer early detection; prognosis; personalized treatment; real-time monitoring
(This special issue belongs to the Section Methods and Technologies Development)
Advances in Surgical and Multimodal Treatments of Hepatopancreatobiliary Cancers
edited by , Matteo Serenari and
submission deadline 31 Jan 2027 | 2 articles | Viewed by 2967 | Submission Open
Keywords: pancreatic cancer; liver metastases; hepatocellular carcinoma; cholangiocarcinoma; neuroendocrine tumours; intraductal papillary mucinous neoplasms (IPMN); pancreatic cystic tumours; robotic surgery; laparoscopic surgery; 3D reconstruction; liver hypertrophy
(This special issue belongs to the Section Cancer Therapy)
Biologic Advancements in Childhood and Adolescent Cancers: From Disease Mechanisms to Precision Therapies
edited by and Eleni Tsotridou
submission deadline 31 Jan 2027 | 1 articles | Viewed by 2905 | Submission Open
Keywords: pediatric oncology; precision therapies; molecular vulnerabilities; biomarker-driven trials; disease mechanisms
(This special issue belongs to the Section Pediatric Oncology)
Surgical and Non-Surgical Convergence in Hepatocellular Carcinoma
edited by
submission deadline 31 Jan 2027 | 2 articles | Viewed by 2877 | Submission Open
Keywords: hepatocellular carcinoma; conversion therapy; HCC treatment boundaries; surgical–non-surgical convergence; multidisciplinary HCC management
(This special issue belongs to the Section Cancer Therapy)
Thyroid Cancer: Diagnosis, Prognosis and Treatment—3rd Edition submission deadline 31 Jan 2027 | 3 articles | Viewed by 2847 | Submission Open
Keywords: thyroid cancer; ultrasound; molecular imaging; fine-needle aspiration cytology; thyroidectomy; radioactive iodine; radioiodine-refractory thyroid cancer; tyrosine kinase inhibitors
Precision Medicine in Acute Myeloid Leukemia
edited by
submission deadline 31 Jan 2027 | 3 articles | Viewed by 2473 | Submission Open
Keywords: acute myeloid leukemia; precision medicine; molecular targeting; DNA sequencing
Novel Genomic Strategies for Personalized Cancer Treatment
edited by Honey Reddi and
submission deadline 31 Jan 2027 | 2 articles | Viewed by 2209 | Submission Open
Keywords: precision medicine; assay validation; solid tumors; molecular methodologies; liquid biopsy
(This special issue belongs to the Section Molecular Cancer Biology)
Tumorigenesis and Tumor Microenvironment—Insights and Interventions (TTMII) submission deadline 31 Jan 2027 | 2 articles | Viewed by 2120 | Submission Open
Keywords: tumorigenesis; tumor microenvironment; intervention; stress biology; aging; mortalin; CARF; ashwagandha; propolis; curcumin; natural compounds
(This special issue belongs to the Section Tumor Microenvironment)
Mechanisms of Therapy Resistance in Cancers—2nd Edition
edited by
submission deadline 31 Jan 2027 | 1 articles | Viewed by 1987 | Submission Open
Keywords: ATP-binding cassette transporters; cancer stem cells; extracellular ATP; repair of DNA damage; immunotherapy resistance
(This special issue belongs to the Section Cancer Drug Development)
Advances in Electroporation-Based Technologies for Cancer Treatment submission deadline 31 Jan 2027 | 1 articles | Viewed by 1963 | Submission Open
Keywords: electroporation; electrochemotherapy; gene electrotransfer; interleukin-12; DNA vaccination; irreversible electroporation; cancer immunotherapy; tumor ablation
(This special issue belongs to the Section Methods and Technologies Development)
New Perspectives in Skin Cancer: From Biology to Therapy
edited by Marija Buljan
submission deadline 31 Jan 2027 | 3 articles | Viewed by 1947 | Submission Open
Keywords: skin cancer; melanoma and non-melanoma skin cancer; tumor biology; early diagnosis; targeted therapy; immunotherapy; epidemiology
Means of Improving Gastric Cancer Response to Chemotherapy and Immunotherapy
edited by and
submission deadline 31 Jan 2027 | 1 articles | Viewed by 1832 | Submission Open
Keywords: gastric cancer; chemotherapy response; immunotherapy; treatment adherence; adverse event management; oncology pharmacy; pharmacist intervention; oral anticancer agents; medication safety
Circulating Tumor DNA and Liquid Biopsy
edited by Atocha Romero
submission deadline 31 Jan 2027 | 1 articles | Viewed by 1693 | Submission Open
Keywords: ctDNA; MRD; fragmentomics; extracellular vesicles (EVs); cell-free RNA (cfRNA); cell-free DNA (cfDNA); and microRNA (miRNA)
(This special issue belongs to the Section Tumor Microenvironment)
ALK in Cancer: Lessons From the Future (2nd Edition) submission deadline 31 Jan 2027 | 2 articles | Viewed by 1655 | Submission Open
Keywords: ALK inhibitors; ALK fusion variants; TP53 mutations; immunotherapy; liquid biopsies; disease monitoring; therapeutic sequencing
(This special issue belongs to the Section Cancer Pathophysiology)
Radiologic Imaging of Hepatocellular Carcinomas submission deadline 31 Jan 2027 | 1 articles | Viewed by 1332 | Submission Open
Keywords: machine learning/deep learning; radiomics; imaging biomarkers; hepatocellular carcinoma; CT; MRI; PET/CT; Gd-EOB-DTPA; LI-RADS; therapeutic response assessment
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
Advances in Peripheral Nerve Tumors
edited by
submission deadline 31 Jan 2027 | 2 articles | Viewed by 1312 | Submission Open
Keywords: electrophysiology; malignant peripheral nerve sheath tumors; nerve sheath collision tumors; neurofibromas; neurofibromatosis type 1; NF2-associated schwannomatosis; non-NF2-associated schwannomatosis; schwannomas; untypical neurofibromas of uncertain biological potential
Advances in Acute Lymphoblastic Leukemia Treatment
edited by
submission deadline 31 Jan 2027 | 1 articles | Viewed by 1308 | Submission Open
Keywords: acute lymphoblastic leukemia; biology; clinical trial; treatment; chemotherapy; immunotherapy
(This special issue belongs to the Section Cancer Therapy)
Metals in Cancer: From Molecular Mechanisms to Innovative Therapeutics submission deadline 31 Jan 2027 | 1 articles | Viewed by 1132 | Submission Open
Keywords: essential and toxic metals; metal-induced carcinogenesis; metal homeostasis; metallotherapeutics; oxidative stress; tumor microenvironment; immune modulation; metabolic reprogramming; therapy resistance; drug delivery systems
(This special issue belongs to the Section Molecular Cancer Biology)
Laryngeal Cancer: Diagnostic Workup, Treatment, and Complications
edited by Francesco Mattioli, and Edoardo Serafini
submission deadline 31 Jan 2027 | 1 articles | Viewed by 1013 | Submission Open
Keywords: laryngeal cancers; diagnosis; laryngeal surgery; transoral laser microsurgery; transoral robotic surgery
(This special issue belongs to the Section Clinical Research in Cancer)
Machine Learning and Artificial Intelligence in Leukemia
edited by Garrett M. Dancik and
submission deadline 31 Jan 2027 | 1 articles | Viewed by 931 | Submission Open
Keywords: cancer genomics; genomic sequencing; biomarkers; predictive modeling; machine learning; artificial intelligence; leukemia; computer vision; natural language processing
(This special issue belongs to the Section Methods and Technologies Development)
Resection and Reconstruction for Breast Cancer
edited by Radoslaw Tarkowski and
submission deadline 31 Jan 2027 | 1 articles | Viewed by 871 | Submission Open
Keywords: oncoplastic breast surgery; breast reconstruction; breast cancer
(This special issue belongs to the Section Clinical Research in Cancer)
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