Innovations in Active Surveillance Management of Early Prostate Cancer

A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Epidemiology and Prevention".

Deadline for manuscript submissions: 8 August 2026 | Viewed by 13

Special Issue Editor


E-Mail Website
Guest Editor
1. Cambridge Prostate Cancer Research and Clinical Trials Group, Cambridge, UK
2. Department of Surgery, University of Cambridge, Cambridge, UK
3. Department of Urology, Cambridge University Hospitals, Cambridge, UK
Interests: prostate cancer; risk stratification; active surveillance; prognostic markers; translational research

Special Issue Information

Dear Colleagues,

Prostate cancer is the most common cancer diagnosed in the West and the second most common male cancer globally. The majority of diagnosed men, however, will live with rather than die from prostate cancer. For many men, treatment may in fact only bring harm without any tangible survival benefit. Active surveillance is a disease management strategy that monitors early prostate cancer with a low probability of ever causing harm in a patient’s natural lifetime. In modern PSA-detected prostate cancer populations, up to a quarter of men diagnosed may be eligible for active surveillance.

Despite its importance as a management option in clinical practice, most academic literature on active surveillance is based on data extrapolated from other treatments or from expert/consensus opinion. In this Special Issue of Cancers, we seek to address this evidence gap by highlighting research that has been based on investigating cohorts of men on surveillance and in whom clinic-pathological features, prediction tools, imaging, or biomarkers have been tested and explored. We particularly welcome articles that look at the natural history of early cancers, methods for risk-adapted surveillance, and tools that may detect progression to a clinically meaningful endpoint. We look forward to receiving your submissions.

Prof. Dr. Vincent J. Gnanapragasam
Guest Editor

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Keywords

  • prostate cancer
  • risk stratification
  • active surveillance
  • predictive markers
  • personalized management
  • imaging
  • biomarkers
  • clinical pathways
  • patient outcomes
  • standardizing care
  • attrition
  • cohort studies

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Published Papers

This special issue is now open for submission.
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