Advances in Electroporation-Based Technologies for Cancer Treatment
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Methods and Technologies Development".
Deadline for manuscript submissions: 31 July 2026 | Viewed by 14
Special Issue Editors
2. Biotechnical Faculty, University of Ljubljana, 1000 Ljubljana, Slovenia
Interests: combining radiotherapy with immune gene therapy; electroporation-based treatments
2. Faculty of Health Sciences, University of Ljubljana, 1000 Ljubljana, Slovenia
Interests: tumor biology; electroporation-based treatments
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Electroporation-based technologies are changing the landscape of cancer therapy by enabling the precise local delivery of therapeutic molecules into tumors. Electrochemotherapy has become a clinically established modality for the treatment of cutaneous and subcutaneous malignancies, while non-thermal irreversible electroporation offers a unique approach for the ablation of deep-seated tumors without thermal damage. Gene electrotransfer extends this platform by enabling the local expression of therapeutic genes, including immunostimulatory cytokines such as interleukin-12. Clinical trials in melanoma and head and neck cancer have demonstrated both safety and antitumor activity. Despite these advances, the optimization of delivery protocols, enhancement of the immune response, and translation from local to systemic effects remain an ongoing challenge.
This Special Issue will focus on the pre-clinical and clinical innovative research and translational advances that could help electroporation-based cancer therapies achieve broader clinical application.
Dr. Bostjan Markelc
Prof. Dr. Gregor Sersa
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- electroporation
- electrochemotherapy
- gene electrotransfer
- interleukin-12
- DNA vaccination
- irreversible electroporation
- cancer immunotherapy
- tumor ablation
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