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Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Cancer Cell Death and Immune Response

edited by Seema Singh and

Amod Sharma

submission deadline 25 Dec 2026 | 1 articles | Viewed by 1911 | Submission Open

Keywords: immunogenic cell death; tumor immunity; epigenetics; apoptosis; tumor microenvironment; biomarkers

(This special issue belongs to the Section Molecular Cancer Biology)

Toxicities of Antineoplastic Therapies

edited by Ysabella Van Sebille,

Hannah Wardill

and

Connor Williams

submission deadline 25 Dec 2026 | Viewed by 448 | Submission Open

Keywords: antineoplastic therpay; cancer treatment-related toxicities; cancer treatment adverse events; chemotherapy toxicity; targeted therapy toxicities; immunotherapy toxicity; hormonal therapy toxicity; radiation-induced toxicity; cellular and gene therapy toxicity; supportive cancer care; survivorship; patient-reported outcomes; toxicity management

(This special issue belongs to the Section Cancer Therapy)

Tumor–Microbiota Crosstalk: Immune Modulation and Resistance to Cancer Therapies

edited by

Massimiliano Berretta

submission deadline 25 Dec 2026 | Viewed by 421 | Submission Open

Keywords: tumor–microbiota; immune modulation; cancer therapies

(This special issue belongs to the Section Infectious Agents and Cancer)

Surgery for Thoracic Cancer

edited by Andrea Billé and Akshay Patel

submission deadline 25 Dec 2026 | Viewed by 362 | Submission Open

Keywords: thoracic surgery; lung cancer; mesothelioma; thymic malignancies; minimally invasive surgery; robotic-assisted thoracic surgery; multimodal therapy; immunotherapy; perioperative management; surgical outcomes

(This special issue belongs to the Section Cancer Therapy)

Epitranscriptomics and the Tumor Microenvironment

edited by

Reza Izadpanah

submission deadline 25 Dec 2026 | Viewed by 280 | Submission Open

Keywords: epitranscriptomics; tumor microenvironment; immune

(This special issue belongs to the Section Tumor Microenvironment)

Minimally Invasive Methods for MRD Monitoring and Diagnosis in Multiple Myeloma

edited by

Joaquín Martínez-López

submission deadline 25 Dec 2026 | Viewed by 216 | Submission Open

Keywords: liquid biopsy; circulating tumor DNA; ctDNA; cfDNA; multiple myeloma; minimal residual disease; disease monitoring; precision medicine

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

AI-Driven Oncology: Advancing Cancer Detection, Diagnosis, and Personalized Treatment

edited by

Mohamed Shehata

and

Fatma M. Talaat

submission deadline 30 Dec 2026 | 10 articles | Viewed by 14214 | Submission Open

Keywords: cancer detection and diagnosis; AI in oncology; explainable AI (XAI); precision oncology; medical imaging; prognostic biomarkers; clinical decision support systems

(This special issue belongs to the Section Methods and Technologies Development)

Multidisciplinary Approaches in Oral Cancer: Pathology, Imaging, and Patient-Centered Outcomes

edited by

André Luiz Sena Guimarães

submission deadline 30 Dec 2026 | 2 articles | Viewed by 1097 | Submission Open

Keywords: oral cancer; oral squamous cell carcinoma; pathology; imaging; supportive care; quality of life; patient-reported outcomes; radiotherapy-related complications; survivorship

Multimodality Imaging for More Precise Radiotherapy (2nd Edition)

edited by Stefano Arcangeli,

Denis Panizza

and

Valeria Faccenda

submission deadline 30 Dec 2026 | 2 articles | Viewed by 943 | Submission Open

Keywords: multimodality imaging; radiotherapy; stereotactic radiotherapy

(This special issue belongs to the Section Cancer Therapy)

Castration- and Therapy-Resistant Prostate Cancer: Biomarkers, Therapeutic Targets, and Emerging Approaches

edited by

Pia Giovannelli

submission deadline 30 Dec 2026 | 1 articles | Viewed by 771 | Submission Open

Keywords: castration-resistant prostate cancer; therapy-resistant prostate cancer; androgen receptor signaling; EGFR-related signaling; biomarkers; drug resistance; signal transduction pathways; translational research; targeted therapy

(This special issue belongs to the Section Molecular Cancer Biology)

Personalizing Genitourinary Cancer Care

edited by

Soum D. Lokeshwar

submission deadline 30 Dec 2026 | 1 articles | Viewed by 648 | Submission Open

Keywords: prostate cancer; bladder cancer; kidney cancer; testicular cancer; cancer diagnostics; translational research; perioperative optimization

(This special issue belongs to the Section Clinical Research in Cancer)

Innovation and Optimization of Radiation or Drug Therapy for Gynecological Cancers

edited by

Hong Zhu

and

Yangying Zhou

submission deadline 30 Dec 2026 | 1 articles | Viewed by 637 | Submission Open

Keywords: cervical cancer; endometrial cancer; ovarian cancer; radiation therapy; immunotherapy; targeted therapy; comprehensive treatment; cost-effectiveness

(This special issue belongs to the Section Cancer Therapy)

Surgical Oncology: Innovations in Precision, Multimodal, and Technology-Driven Cancer Care

edited by Fabio Pacelli and Giorgio D’Annibale

submission deadline 30 Dec 2026 | 1 articles | Viewed by 635 | Submission Open

Keywords: surgical oncology; complex cancer surgery; precision surgery; peritoneal surface malignancies; retroperitoneal tumors; cytoreductive surgery; HIPEC; minimally invasive surgery; robotic surgery; multimodal treatment

Immunotherapy with Checkpoint Inhibitors for Non-Small-Cell Lung Cancer (2nd Edition)

edited by

Alessandro Inno

and

Diego Signorelli

submission deadline 30 Dec 2026 | Viewed by 383 | Submission Open

Keywords: immune-checkpoint inhibitors; non-small cell lung cancer; neoadjuvant therapy; adjuvant therapy; primary resistance; acquired; resistance; biomarkers; immune-related adverse events

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

KRAS-Driven Lung Cancer: Heterogeneity, Microenvironment, and Therapeutic Innovation

edited by

Haitang Yang

submission deadline 30 Dec 2026 | Viewed by 270 | Submission Open

Keywords: KRAS mutation; targeted therapy; immunotherapy; tumor microenvironment; heterogeneity

Advances in Surgical Strategies for Gynecologic Malignancies

edited by Krzysztof Nowosielski, Paweł Grzegorz Knapp and Joanna P. Kacperczyk-Bartnik

submission deadline 30 Dec 2026 | Viewed by 238 | Submission Open

Keywords: gynecological cancer; cytoreductive surgeries; peritoneal surface malignancy; surgical techniques; prehabilitation; sexuality; perioperative cancer management; minimal invasive surgery; robotic surgery

Gastrointestinal Cancer Surgery

edited by Florian Primavesi and

Daniel Neureiter

submission deadline 31 Dec 2026 | 6 articles | Viewed by 17994 | Submission Open

Keywords: gastrointestinal cancer surgery; precision surgery; personalized medicine; robotics; pathology; colorectal cancer; stomach cancer; pancreatic cancer; hepatocellular cancer; biliary tract cancer

(This special issue belongs to the Section Cancer Therapy)

Feature Papers in the Section “Cancer Therapy” in 2025-2026

edited by

Abdullah Esmail

, Qiang Wang and

Hiroyuki Takei

submission deadline 31 Dec 2026 | 10 articles | Viewed by 14937 | Submission Open

Keywords: chemotherapy; immunotherapy for cancer; oncology; systemic treatment and targeted therapy.

(This special issue belongs to the Section Cancer Therapy)

Neuroendocrine Neoplasms: Pathogenesis, Diagnostics, and Therapy

edited by

Beata Jabłońska

submission deadline 31 Dec 2026 | 4 articles | Viewed by 14184 | Submission Open

Keywords: neuroendocrine neoplasms; pathogenesis; diagnostics; therapy

(This special issue belongs to the Section Cancer Therapy)

Feature Paper in Section ‘Cancer Epidemiology and Prevention’ in 2025-2026

edited by Roger Anderson and

Paweł Koczkodaj

submission deadline 31 Dec 2026 | 6 articles | Viewed by 14062 | Submission Open

Keywords: cancer prevention; cancer epidemiology; health policy; public health; global health; health education; health promotion

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Recent Advances in Hematological Malignancies in Children

edited by

Radosław Chaber

submission deadline 31 Dec 2026 | 4 articles | Viewed by 13823 | Submission Open

Keywords: acute lymphoblastic leukemia; acute myeloid leukemia; hematological malignancies in children; diagnostic and therapeutic methods; supportive care strategies

(This special issue belongs to the Section Pediatric Oncology)

Viral Oncogenes and Their Role in Cancer Pathogenesis

edited by

Ronen Borenstein

and Yosef Sabo

submission deadline 31 Dec 2026 | 4 articles | Viewed by 12097 | Submission Open

Keywords: viral oncogenes; cancer pathogenesis; cellular regulation; tumorigenesis mechanisms; antiviral and anticancer strategies

(This special issue belongs to the Section Infectious Agents and Cancer)

Rehabilitation Opportunities in Cancer Survivorship

edited by

Marie Carmen Valenza

and Alejandro Heredia-Ciuro

submission deadline 31 Dec 2026 | 3 articles | Viewed by 10356 | Submission Open

Keywords: cancer; rehabilitation; sequelae; disability; impairment

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Challenges and New Developments in the Diagnosis and Treatment of Sarcoma

edited by

Xiaolan Feng

submission deadline 31 Dec 2026 | 4 articles | Viewed by 9487 | Submission Open

Keywords: bone and soft tissue sarcoma; prognostic and predictive biomarker; transcriptomic/genomic profiling; immunotherapy; targeted treatment

(This special issue belongs to the Section Cancer Therapy)

Immune Biomarkers in Solid Tumors: From Peripheral Blood Parameters to Tissue-Based Indicators for Prognosis and Therapy Response

edited by

Ioannis P. Trontzas

and

Konstantinos Syrigos

submission deadline 31 Dec 2026 | 4 articles | Viewed by 9427 | Submission Open

Keywords: immune biomarkers; solid tumors; peripheral blood immune parameters; circulating immune cells; cytokines; tissue-based biomarkers; immune checkpoint molecules; prognostic biomarkers; predictive biomarkers; tumor microenvironment; immunotherapy response; translational oncology

(This special issue belongs to the Section Cancer Biomarkers)

Advances in Radiology for the Detection, Diagnosis, and Management of Breast Cancer

edited by Takouhie Catherine Maldjian and Mary M. Salvatore

submission deadline 31 Dec 2026 | 6 articles | Viewed by 8494 | Submission Open

Keywords: breast cancer; radiology; breast imaging; mammography; MRI; ultrasound; AI; radiomics; diagnosis; treatment response; image-guided biopsy

(This special issue belongs to the Section Methods and Technologies Development)

Classification, Risk Assessment and Clinical Management of Malignant Thyroid Nodules: 2nd Edition

edited by Claudio Spinelli and Marco Ghionzoli

submission deadline 31 Dec 2026 | 4 articles | Viewed by 8231 | Submission Open

Keywords: thyroid nodule; thyroid cancer; guidelines; surgery

(This special issue belongs to the Section Clinical Research in Cancer)

Recent Advances in Epidemiology of Childhood Cancer

edited by Rafael Peris-Bonet,

Rebeca Ramis

and Adela Cañete

submission deadline 31 Dec 2026 | 7 articles | Viewed by 7727 | Submission Open

Keywords: childhood cancer epidemiology; childhood cancer registries; environmental causes of childhood cancer; genetic epidemiology; molecular epidemiology; survival of children with cancer; quality of life; social determinants and inequalities; information technologies and statistical innovations

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Advances in Targeted Therapies in Cancer (2nd Edition)

edited by

Bulent Ozpolat

submission deadline 31 Dec 2026 | 3 articles | Viewed by 7093 | Submission Open

Keywords: targeted therapy; cancer, antibody therapy; small molecule inhibitor; RNAi therapy; cell-based therapy

(This special issue belongs to the Section Cancer Therapy)

Molecular Pathology and Human Cancers

edited by

Stefano Marletta

, Alessandro Russo and Giuliana Pavone

submission deadline 31 Dec 2026 | 3 articles | Viewed by 6796 | Submission Open

Keywords: molecular pathology; cancer pathogenesis; targeted therapy; personalized medicine; cancer signaling

(This special issue belongs to the Section Cancer Pathophysiology)

Focus on Focal Therapy for Prostate Cancer

edited by Abhinav Sidana and Samuel Tremblay

submission deadline 31 Dec 2026 | 3 articles | Viewed by 6369 | Submission Open

Keywords: focal therapy; prostate cancer treatment; image-guided therapy; oncological outcomes; functional outcome; patient selection; surveillance

(This special issue belongs to the Section Cancer Therapy)

Contemporary Management for Gallbladder Cancer: From Diagnosis to Treatment (2nd Edition)

edited by Hiromichi Ito

submission deadline 31 Dec 2026 | 2 articles | Viewed by 6150 | Submission Open

Keywords: gallbladder cancer; radical cholecystectomy; adjuvant chemotherapy; neoadjuvant therapy; incidental gallbladder cancer; multidisciplinary management; preoperative staging

(This special issue belongs to the Section Cancer Therapy)

The Role of Circulating Tumor Cells in Colorectal Cancer

edited by

Chiara Nicolazzo

submission deadline 31 Dec 2026 | 2 articles | Viewed by 6114 | Submission Open

Keywords: circulating tumor cells (CTC); colorectal cancer (CRC); liquid biopsy; biomarkers; tumor progression; personalized medicine; molecular profiling; metastasis; diagnostic techniques; prognostic evaluation

(This special issue belongs to the Section Cancer Biomarkers)

Molecular and Genetic Biomarkers in Oral Squamous Cell Carcinoma

edited by

Kalu U.E. Ogbureke

submission deadline 31 Dec 2026 | 3 articles | Viewed by 5831 | Submission Open

Keywords: oral cancer; oropharyngeal cancer; biomarkers; liquid biopsy; genetic determinants

(This special issue belongs to the Section Cancer Biomarkers)

Radiation Therapy in Oncology

edited by Jerzy Wydmański

submission deadline 31 Dec 2026 | 5 articles | Viewed by 5462 | Submission Open

Keywords: radiotherapy; radiation injury; systemic therapy; immunotherapy; cancer; concurrent chemoradiotherapy; stereotactic radiotherapy

(This special issue belongs to the Section Cancer Therapy)

Novel Strategies to Fight Metastatic Breast Cancer

edited by

Fernando Schmitt

and

Nuno Vale

submission deadline 31 Dec 2026 | 3 articles | Viewed by 5374 | Submission Open

Keywords: breast cancer; metastasis; targeted therapy; biomarkers; personalized medicine; prognosis

(This special issue belongs to the Section Molecular Cancer Biology)

Clinical Pathology of Lung Cancer (2nd Edition)

edited by

Letizia Gnetti

submission deadline 31 Dec 2026 | 3 articles | Viewed by 5352 | Submission Open

Keywords: lung cancer; pathology; diagnosis; treatment; targeted therapies; immunotherapy

(This special issue belongs to the Section Clinical Research in Cancer)

Cancer Cell Vulnerabilities on Pathways Regulating the Cell Cycle

edited by

Hiroaki Kiyokawa

submission deadline 31 Dec 2026 | 3 articles | Viewed by 5084 | Submission Open

Keywords: cell cycle; signaling pathway; precision medicine

(This special issue belongs to the Section Molecular Cancer Biology)

Cancer-Associated Thrombosis, Arterial and Venous Thromboembolism

edited by

Omer Iqbal

submission deadline 31 Dec 2026 | 5 articles | Viewed by 4966 | Submission Open

Keywords: cancer; deep vein thrombosis; pulmonary embolism; venous thromboembolism; anticoagulants; cardio-oncology; artificial intelligence; machine learning

(This special issue belongs to the Section Cancer Pathophysiology)

Multiple Myeloma—Biology, Diagnosis, Treatment and Prognosis (2nd Edition)

edited by

Cirino Botta

submission deadline 31 Dec 2026 | 3 articles | Viewed by 4909 | Submission Open

Keywords: multiple myeloma; bone marrow microenvironment; minimal residual disease; mass spectrometry; flow cytometry; CAR-T; bispecific agents; genomic alterations

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Genetic Alterations and Features in the Development of Gastrointestinal Cancer

edited by

Alexandra Voutsina

submission deadline 31 Dec 2026 | 1 articles | Viewed by 4873 | Submission Open

Keywords: gastrointestinal cancers; genetic alteration; epigenetic regulation; the mechanism of tumorigenesis; precision treatment

(This special issue belongs to the Section Molecular Cancer Biology)

Advances in Cancer Survival Analysis

edited by

Tianhui (Thomas) Chen

, Jianguang Ji and

Jun Lyu

submission deadline 31 Dec 2026 | 3 articles | Viewed by 4760 | Submission Open

Keywords: cancer burden; cancer survival; epidemiology; survival analysis methodology; cancer screening; cancer control; cancer prognosis; cancer data mining

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Head and Neck Cancer: MRI and PET/CT Diagnosis and Surgical Treatment

edited by

Lavinia Manuela Lenghel

submission deadline 31 Dec 2026 | 2 articles | Viewed by 4194 | Submission Open

Keywords: head and neck cancer; MRI; PET/CT; diagnostic imaging; surgical treatment; tumor staging; image-guided surgery; multidisciplinary approach; oncologic outcomes

(This special issue belongs to the Section Cancer Therapy)

Soft Tissue Sarcomas—New Diagnostic and Therapeutic Perspectives Through Clinical Genomic Profiling

edited by

Ewa Koscielniak

and

Monika Sparber-Sauer

submission deadline 31 Dec 2026 | 3 articles | Viewed by 4072 | Submission Open

Keywords: soft tissue sarcoma; molecular profiling; cancer genomics; personalized medicine

(This special issue belongs to the Section Cancer Therapy)

Molecular Advances in Lung Cancer: From Pathogenesis to Precision Therapy (2nd Edition)

edited by

Federico Pio Fabrizio

submission deadline 31 Dec 2026 | 2 articles | Viewed by 3914 | Submission Open

Keywords: lung cancer molecular biology; targeted therapy; precision medicine; biomarkers; therapeutic resistance

(This special issue belongs to the Section Molecular Cancer Biology)

Tumor Suppressor Genes and Oncogenes: Genome-Wide Insights into Cancer Biology

edited by

Meena Kanduri

submission deadline 31 Dec 2026 | 2 articles | Viewed by 3890 | Submission Open

Keywords: tumor suppressor genes; oncogenes; cancer; genome analysis; cancer mutations; DNA methylation; histone modification; cancer progression; oncogenesis

(This special issue belongs to the Section Molecular Cancer Biology)

Nanomedicine’s Role in Oncology

edited by

Efstathios Efstathopoulos

and

Ellas Spyratou

submission deadline 31 Dec 2026 | 1 articles | Viewed by 3793 | Submission Open

Keywords: nanomedicine; oncology; interventional oncology; nanotechnology development; cancer diagnosis; cancer treatment; cancer imaging

(This special issue belongs to the Section Methods and Technologies Development)

Updates on Anti-Cancer Drug Research

edited by

Ana Luísa De Sousa-Coelho

and Mónica Fernandes

submission deadline 31 Dec 2026 | 3 articles | Viewed by 3515 | Submission Open

Keywords: anti-cancer drug research; drug resistance; biomarkers; pharmacogenomics; single-cell RNA sequencing; non-coding RNAs; multi-omics data

(This special issue belongs to the Section Cancer Drug Development)

PARP Inhibitors in Cancer Therapy

edited by

Jie Jiang

and

Fu Gui

submission deadline 31 Dec 2026 | 2 articles | Viewed by 3505 | Submission Open

Keywords: PARP inhibitors; cancer therapy; DNA damage repair; drug discovery

(This special issue belongs to the Section Cancer Therapy)

Genomic and Epigenomic Aberrations in Cancer

edited by

Xiaofan Ding

submission deadline 31 Dec 2026 | 2 articles | Viewed by 3271 | Submission Open

Keywords: genomic mutation; epigenetic alteration; functional genomics

(This special issue belongs to the Section Molecular Cancer Biology)

Displaying special issue 451-500 on page 10 of 22.

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