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Toxicities of Antineoplastic Therapies

A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Therapy".

Deadline for manuscript submissions: 31 May 2026 | Viewed by 21

Special Issue Editors


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Guest Editor
School of Biomedicine, University of South Australia, Adelaide, SA 5000, Australia
Interests: digital health; mHealth; supportive care in cancer

E-Mail Website
Guest Editor
School of Biomedicine, The University of Adelaide, Adelaide, SA 5000, Australia
Interests: supportive cancer care; survivorship; precision medicine; risk prediction; personalised cancer care; host-microbe interactions
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
School of Biomedicine, University of South Australia, Adelaide, SA 5000, Australia
Interests: toxicities associated with chemotherapy and radiotherapy

Special Issue Information

Dear Colleagues,

The rapid development of antineoplastic therapies, including cytotoxic agents, targeted therapies, immune checkpoint inhibitors, and cellular therapies, has transformed cancer treatment and improved survival across a wide range of malignancies. These advances have shifted many cancers toward chronic disease management, offering prolonged control and durable responses. However, this progress has been accompanied by an expanding spectrum of toxicities that can affect virtually every organ system. Such adverse effects may limit therapeutic efficacy, impair quality of life, and, in severe cases, necessitate treatment interruption or discontinuation. 

Identification of predictive biomarkers, refinement of monitoring strategies, and development of effective supportive care strategies to mitigate both acute and long-term complications of antineoplastic therapies continue to rise as key priorities in advancing modern cancer care. Continued high-quality research into the biological mechanisms underlying these toxicities and their clinical manifestations is essential to optimize therapeutic benefit, minimize harm, and ensure that advances in cancer therapy translate into meaningful improvements in patient outcomes. 

This Special issue aims to highlight recent advances in the characterization, mechanisms, and management of toxicities associated with antineoplastic therapies. 

We welcome original research articles and reviews.  

Dr. Ysabella Van Sebille
Dr. Hannah Wardill
Dr. Connor Williams
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • antineoplastic therpay
  • cancer treatment-related toxicities
  • cancer treatment adverse events
  • chemotherapy toxicity
  • targeted therapy toxicities
  • immunotherapy toxicity
  • hormonal therapy toxicity
  • radiation-induced toxicity
  • cellular and gene therapy toxicity
  • supportive cancer care
  • survivorship
  • patient-reported outcomes
  • toxicity management

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Published Papers

This special issue is now open for submission.
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