Challenges and New Developments in the Diagnosis and Treatment of Sarcoma
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Therapy".
Deadline for manuscript submissions: 31 December 2025 | Viewed by 350
Special Issue Editor
Interests: prognostic and predictive biomarkers; novel therapeutic intervention through genomic and transcriptome sequencing; clinical, translational research, and clinical trials (breast/sarcoma)
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Due to its extreme rarity, heterogeneity, and complexity, sarcoma is considered one of the most challenging diseases and cancers to diagnose and treat, and it therefore presents a poor prognosis in most advanced or metastatic settings. We are currently facing many challenges in the diagnosis and treatment of sarcoma. With the availability of next-generation sequencing technology, novel fusions have been identified, facilitating the evolution of WHO classification, but the biology of these new fusions is not yet understood. Despite the fact that molecular targeted treatments and immunotherapy have revolutionized treatment in the majority of hematological and solid cancer types, they have not yet been applied to sarcoma. The purpose of this Special Issue is to provide opportunities for sarcoma research communities to contribute new ideas and options to promote better diagnosis and treatment in this deadly disease. For this Special Issue, we welcome the submission of reviews and original research articles, with a deadline of 31 December 2025.
Dr. Xiaolan Feng
Guest Editor
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Keywords
- bone and soft tissue sarcoma
- prognostic and predictive biomarker
- transcriptomic/genomic profiling
- immunotherapy
- targeted treatment
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