Oxidative Stress in Pregnant Women and Fetuses
A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Health Outcomes of Antioxidants and Oxidative Stress".
Deadline for manuscript submissions: 30 November 2025 | Viewed by 133
Special Issue Editors
Interests: pregnancy; lactation; nutrition; perinatal nutrition; oxidative stress; advanced maternal age; antioxidant system; inflammation; placenta; physical activity; endocrine function; early programming
Special Issues, Collections and Topics in MDPI journals
Interests: pregnancy; lactation; nutrition; perinatal nutrition; oxidative stress; antioxidant system; inflammation; physical activity; placenta; advanced maternal age; endocrine function
Special Issues, Collections and Topics in MDPI journals
Interests: physiology; nutrition; molecular biology; fermentation; food sciences; biochemistry; antioxidants; oxidative stress; pediatrics; maternal; prematurity; colostrum; neonatal nutrition; obstetrics and gynecology; perinatal nutrition
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
There is currently growing interest in the role of oxidative stress (OS) during pregnancy. The oxidant status of the cell influences angiogenesis, essential for follicular development, corpus luteum creation, endometrial differentiation, and embryonic growth. In addition, pregnancy naturally increases vulnerability to oxidative stress (OS), a state driven by a systemic inflammatory reaction that causes higher concentrations of reactive oxygen species (ROS) and reactive nitrogen species (RNS) in the bloodstream. Heightened OS during pregnancy can initiate a range of harmful effects in the mother and the fetus, including underdevelopment, irregular placental function, and various complications such as pre-eclampsia, embryonic loss, repeated pregnancy failure, fetal developmental issues, intrauterine growth restriction, and, in severe cases, fetal demise. Reducing the unchecked rise in RNS/ROS levels necessitates trace elements that are involved in both enzymatic and non-enzymatic defense mechanisms. Additionally, the placenta, once regarded merely as a passive link between mother and fetus, is recognized for its essential role in regulating the intrauterine environment, oxidative stress, and fetal growth. Biomarkers measuring the level of oxidative stress can provide indirect evaluations of complications during pregnancy. This Special Issue seeks to emphasize the significance of preserving oxidative and antioxidant equilibrium during pregnancy and the significance of oxidative stress in diseases related to pregnancy.
Prof. Dr. Javier Diaz-Castro
Prof. Dr. Julio J. Ochoa Herrera
Dr. Jorge Moreno-Fernandez
Guest Editors
Manuscript Submission Information
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Keywords
- metabolic programming
- oxidative stress
- antioxidants
- mitochondria
- inflammatory signaling
- reactive oxygen species
- reactive nitrogen species
- placenta
- trace elements
- nutrition
- gestation
- offspring
- pregnancy
- breastfeeding
- fetus
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