Phenolics as Antioxidant Agents—2nd Edition
A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Natural and Synthetic Antioxidants".
Deadline for manuscript submissions: 10 December 2025 | Viewed by 19
Special Issue Editor
Interests: crop production; cultural practices and influence in plant composition; plant composition and metabolomic analysis; plant composition and health effects; an agroecosystems
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This second edition of “Phenolics as Antioxidant Agents” offers a comprehensive and authoritative overview of the latest scientific and technological advancements in relation to phenolic compounds and their role as antioxidants. This Special Issue should transcend basic chemical characteristics into the mechanistic insights, functional properties, and interdisciplinary applications of phenolics in both food and biomedical sciences. Particular focus is given to recent innovations in sustainable extraction technologies that enhance the recovery and purity of phenolic compounds from natural sources, aligning with the principles of green chemistry. The exploration of structure–activity relationships (SARs) is crucial, providing a deeper understanding of how molecular configurations affect antioxidant capacity. Additionally, this Special Issue encompasses advanced analytical methodologies, including in vitro and in vivo models, omics technologies, and computational modeling, which collectively broaden our comprehension of phenolic behavior in complex biological systems. Of equal importance is the examination of phenolics’ therapeutic potential in mitigating oxidative stress-related conditions, such as cardiovascular diseases, metabolic disorders, and neurodegenerative illnesses. The comparison between natural and synthetic antioxidants is also timely, given the increasing shift towards clean-label products and naturally derived bioactives in both the food and pharmaceutical industries. This edition not only reflects on the current state of knowledge, but also identifies critical research gaps, proposes innovative applications, and offers strategic directions for future advancements in the field of phenolic antioxidants.
Dr. Alfredo Aires
Guest Editor
Manuscript Submission Information
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Keywords
- antioxidants
- bioactive compounds
- oxidative stress
- structure–activity relationships (SARs)
- sustainable extraction
- green chemistry
- therapeutic potential
- in vitro and in vivo models
- food and biomedical applications
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