Redox Signaling in Cancer: Mechanisms and Therapeutic Opportunities
A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Health Outcomes of Antioxidants and Oxidative Stress".
Deadline for manuscript submissions: 30 November 2025 | Viewed by 578
Special Issue Editor
Interests: ROS; cancer; natural compound; therapeutic; ferroptosis
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Oxidative stress plays a critical role in the development and progression of various cancers. Reactive oxygen species (ROS), when produced in excess, can damage DNA, proteins, and lipids, thereby promoting tumorigenesis. However, recent studies have highlighted the dual role of ROS in cancer, suggesting that elevated oxidative stress can also be exploited for therapeutic purposes by inducing cancer cell death. This Special Issue aims to present the latest research findings on the role of oxidative stress in cancer biology, including but not limited to ROS-mediated signaling pathways, redox regulation, antioxidant defense mechanisms, and oxidative stress-induced cell death (e.g., apoptosis, ferroptosis). We especially welcome original research and reviews that explore the therapeutic potential of natural compounds and targeted interventions that modulate oxidative stress in cancer. Contributions that elucidate the molecular mechanisms underlying oxidative stress-related processes and discuss clinical implications are also encouraged.
We look forward to receiving your valuable contributions to this Special Issue.
Prof. Dr. Myoung Ok Kim
Guest Editor
Manuscript Submission Information
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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed open access monthly journal published by MDPI.
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Keywords
- oxidative stress
- cancer
- reactive oxygen species (ROS)
- redox signaling
- natural compounds
- ferroptosis
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