Advances in Mitochondrial Redox Biology—Second Edition
A special issue of Antioxidants (ISSN 2076-3921).
Deadline for manuscript submissions: 30 November 2025 | Viewed by 17
Special Issue Editor
Interests: reactive oxygen species; redox signaling; vascular endothelial growth factor; angiogenesis; endothelial cells; peripheral arterial disease; diabetes
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Mitochondria are not only the powerhouses of the cell but also central hubs of redox signaling, metabolic adaptation, and cell fate determination. The dynamic interplay between mitochondrial reactive oxygen species (ROS) production, antioxidant defenses, and redox-sensitive signaling pathways governs processes ranging from energy metabolism and inflammation to apoptosis and cellular regeneration. In recent years, mitochondrial redox biology has emerged as a critical field with broad implications for cardiovascular disease, cancer, neurodegeneration, aging, and immunity. Building upon the success of the first edition, this second edition of the Special Issue aims to highlight the latest breakthroughs in mitochondrial redox signaling, oxidative stress regulation, and mitochondrial–nuclear communication. We welcome original research and comprehensive reviews that explore novel mechanisms of redox regulation in mitochondria, the role of mitochondrial dynamics and quality control in redox homeostasis, innovative redox imaging and proteomic approaches, and therapeutic strategies targeting mitochondrial ROS. By gathering cutting-edge research across disciplines, this Special Issue will provide a platform for advancing our understanding of how mitochondrial redox biology drives health and disease. We invite investigators working at the interface of redox biology, bioenergetics, and translational medicine to contribute their work and shape the future of this rapidly evolving field.
Prof. Dr. Masuko Ushio-Fukai
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- mitochondria
- redox signaling
- reactive oxygen species (ROS)
- mitochondrial dynamics
- bioenergetics
- mitochondria–nuclear communication
- aging
- cell metabolism
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