The Role of Oxidative Stress in Environmental Toxicity—2nd Edition

A special issue of Antioxidants (ISSN 2076-3921).

Deadline for manuscript submissions: 10 December 2025 | Viewed by 44

Special Issue Editor


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Guest Editor
Laboratorio de Toxicología Ambiental, Facultad de Química, Universidad Autónoma del Estado de México, Toluca 50120, Mexico
Interests: ecotoxicology; aquatic toxicology; emerging contaminants; ecopharmacovigilance; oxidative stress; teratogenesis; geno- and cytotoxic effects
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Special Issue Information

Dear Colleagues,

The interaction between living organisms and the ever-changing environment, marked by the presence of various pollutants with different origins, constitutes a crucial field of study for understanding environmental and public health. Within this framework, oxidative stress emerges as a fundamental and transversal mechanism in the toxicity induced by a wide range of environmental agents. This Special Issue, titled “The Role of Oxidative Stress in Environmental Toxicity”, is dedicated to the exploration of the intricate relationship between pollutant exposure and alterations in redox balance in biological systems.

Exposure to xenobiotics, ranging from heavy metals, pesticides, and ultrafine particles to persistent organic compounds such as pharmaceuticals, emerging contaminants, and endocrine disruptors, can trigger the excessive generation of reactive oxygen species (ROS) and reactive nitrogen species (RNS). When the production of these species overwhelms the organism’s antioxidant defense systems, a state of oxidative stress is established. This condition can lead to significant molecular damage, affecting lipids, proteins, and nucleic acids and ultimately compromising cellular integrity and function.

In this second edition, we welcome cutting-edge research that contributes to elucidating the ways in which oxidative stress acts as a unifying mechanism of toxicity for diverse classes of environmental pollutants. By deepening our understanding of the molecular and cellular processes underlying this response, we can develop more effective strategies for risk assessment, disease prevention, and the mitigation of the negative impacts of pollution on the health of both ecosystems and populations.

Prof. Dr. Hariz Islas Flores
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • environmental pollutants
  • oxidative stress biomarkers
  • water/air/soil pollution
  • environmental toxicity
  • ROS and RNS

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Published Papers

This special issue is now open for submission.
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